LOCUS       NM_199373               2419 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus guided entry of tail-anchored proteins factor 1
            (Get1), mRNA.
ACCESSION   NM_199373 XM_213646
VERSION     NM_199373.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2419)
  AUTHORS   Vogl,C., Panou,I., Yamanbaeva,G., Wichmann,C., Mangosing,S.J.,
            Vilardi,F., Indzhykulian,A.A., Pangrsic,T., Santarelli,R.,
            Rodriguez-Ballesteros,M., Weber,T., Jung,S., Cardenas,E., Wu,X.,
            Wojcik,S.M., Kwan,K.Y., Del Castillo,I., Schwappach,B.,
            Strenzke,N., Corey,D.P., Lin,S.Y. and Moser,T.
  TITLE     Tryptophan-rich basic protein (WRB) mediates insertion of the
            tail-anchored protein otoferlin and is required for hair cell
            exocytosis and hearing
  JOURNAL   EMBO J 35 (23), 2536-2552 (2016)
   PUBMED   27458190
REFERENCE   2  (bases 1 to 2419)
  AUTHORS   Yamamoto,Y. and Sakisaka,T.
  TITLE     Molecular machinery for insertion of tail-anchored membrane
            proteins into the endoplasmic reticulum membrane in mammalian cells
  JOURNAL   Mol Cell 48 (3), 387-397 (2012)
   PUBMED   23041287
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC062049.1.
            
            On Jan 11, 2004 this sequence version replaced XM_213646.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062049.1, DN937254.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2419
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..2419
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /note="guided entry of tail-anchored proteins factor 1"
                     /db_xref="GeneID:288233"
                     /db_xref="RGD:735104"
     exon            1..171
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..594
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /note="tryptophan-rich protein; tail-anchored protein
                     insertion receptor WRB; tryptophan rich basic protein"
                     /codon_start=1
                     /product="guided entry of tail-anchored proteins factor 1"
                     /protein_id="NP_955405.1"
                     /db_xref="GeneID:288233"
                     /db_xref="RGD:735104"
                     /translation="MSASETDRWAWLLVLCFVFGCNVLRILLPTLSSFISRVLQKDAE
                     QESQMRAEIQSMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKW
                     FISVAFYVLQAALMISLIWKYYSVPVAVVPSKWITPLDRLVAFPTRVAGGIGVTCWIL
                     VCNKVVAIILHPFS"
     exon            172..337
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /inference="alignment:Splign:2.1.0"
     exon            338..405
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /inference="alignment:Splign:2.1.0"
     exon            406..520
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /inference="alignment:Splign:2.1.0"
     exon            521..2406
                     /gene="Get1"
                     /gene_synonym="Wrb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgtaggcg agcgcggagg cgcggtctcc atggcgctgc tgtagcggtg caggtgcctg
       61 ggatccagaa tgagcgcgtc cgagacagat cgctgggcgt ggttgctggt gctgtgcttc
      121 gtgttcgggt gcaacgtgct gcgcatcctt ctgccgacct tgtcctcgtt tatttccagg
      181 gtgctgcaga aggatgcaga gcaggagtca cagatgagag cagagatcca gagcatgaag
      241 caggagctgt ccaccgtcaa catgatggat gagtttgcca gatacgccag gctggagaga
      301 aaaatcaaca aaatgacaga caaactcaaa actcacgtga aggcacggac agctcagttg
      361 gccaagatca agtggtttat aagtgttgct ttctacgtac tacaagcagc gttgatgatc
      421 tcactcatct ggaagtatta ctctgtccct gtggctgtgg tgcccagcaa gtggatcacc
      481 ccactagacc ggctggtggc ctttcctact cgagtagcag gtggaatcgg agtcacctgc
      541 tggattttag tctgcaacaa agtcgtggct atcattctcc accctttcag ctgaggggag
      601 gccagccaca gcctttaccc gagaattctg ttaggtgaag agcggattgc gcacaaggcc
      661 acagattgtt gttttttgtg ttctggagta cgattgcttt tgtgtgtcac ctgggattct
      721 tgttgaagtc aggatttcct atactcgcca ttgagccaga aagaccagtt acgtacggca
      781 ttcccgcact gtctgacgtc tgacgtaact ctggatcctt accgactggg aaccaccacg
      841 tggcatctgc tggtgcttgt tccgcagtga aagtcacact tgtaacagct ccgatagtgc
      901 cgtttctaac tttagaaaaa cccacacttt tgtaccacta ctaaacctcc tttttatctc
      961 acagttgccg agagtgacac atactagtgg atgtcactct gctgtaccct gttgaaatgc
     1021 cacacttcag tgtgtgaaaa gtatcgacgt ttgtctaagc ttgttaattt ttcatagttg
     1081 ctcctacatg tgttcacgag cctacgtata ttttatttaa agcatttcaa tgaagtctgt
     1141 ctttaaagca ttgggcgttt gtgctgtgca gagtggaata gggttaagca aggtgcggtc
     1201 tgatccagtt catctgagac tccagactca tgaagaattc tgccaagtct ggttgttttt
     1261 gttttgcttt tttgagacaa ggtctctcag tgtagctgtg gctgtcctga aatcctctgt
     1321 gtagaccagg cttgtctcaa accctcagag atccacctgc ctctgtctcc gagatggccg
     1381 gattacaggt gtgtgctgca ccaggtggtt ttgaagcact tttgctactt acagtgtttg
     1441 ccagtgctag cgtgactgtt ccagtagcca tactgcagga gtcgtctggg ctgcaagctg
     1501 tgggattgcc tctagggaag catagcatag aaaatccacc tgccagcact gcatgtctgc
     1561 acagctctgg ctgccctgga attacaatgt agaccaggat gacctggaat ttacagaagc
     1621 cctcttgcct ctgcctcaga gctgccggga ttaaaggcat gcactgggtt tcgaaggatc
     1681 gtatttatat tcctgcgttt cctaatctaa gacctcctaa gtagctcttt gttactttga
     1741 ctgtactgtg aatgcatgta ctgtgaagtg catggccctt gggttggttg taggctgagt
     1801 gccaccagag cagtccactg atttaaactc accagatgct gcagatagat ccacgtggta
     1861 ccaaggttac ttggctgtac ttgtaatggg cacgaatggg atacagcagt aggcacagct
     1921 agcaatgcca ggagaacctg cccactagct ccagcatgct caccccaagg aagcacttgg
     1981 tctacacaag attagttcag gacctgagga ggttggctgc agcatctggg ttccctccag
     2041 ggacccagcc cttggtgtgg ggagggtgtg tggtagtgaa ctgcagtctg aggtggtgct
     2101 ttttgcccat gtcatttagg tagccagggt cagtatctgg ctttcaccac tgaaagggtg
     2161 cccagaccag atgcctctca cagaactcat catttcagcc gatctgaagg aacaagcgac
     2221 tgttagtgtt cctgtgtgtg tataacatgg atgtcagcac ttccacatgc gtaatgtgtg
     2281 ttatgttccc atgtatgcag tgtatgtaac accaagtagg ggacatcagt gtgttttacc
     2341 cccaaattgt atttgtttaa aaatgggtaa taaacattga gttaaaaagg gactaggtca
     2401 acatcaaaaa aaaaaaaaa
//
