LOCUS       NM_001009466            1201 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus gem (nuclear organelle) associated protein 6
            (Gemin6), transcript variant 1, mRNA.
ACCESSION   NM_001009466 XM_343004
VERSION     NM_001009466.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Yong,J., Kasim,M., Bachorik,J.L., Wan,L. and Dreyfuss,G.
  TITLE     Gemin5 delivers snRNA precursors to the SMN complex for snRNP
            biogenesis
  JOURNAL   Mol Cell 38 (4), 551-562 (2010)
   PUBMED   20513430
REFERENCE   2  (bases 1 to 1201)
  AUTHORS   Chari,A., Golas,M.M., Klingenhager,M., Neuenkirchen,N., Sander,B.,
            Englbrecht,C., Sickmann,A., Stark,H. and Fischer,U.
  TITLE     An assembly chaperone collaborates with the SMN complex to generate
            spliceosomal SnRNPs
  JOURNAL   Cell 135 (3), 497-509 (2008)
   PUBMED   18984161
REFERENCE   3  (bases 1 to 1201)
  AUTHORS   Pellizzoni,L., Baccon,J., Rappsilber,J., Mann,M. and Dreyfuss,G.
  TITLE     Purification of native survival of motor neurons complexes and
            identification of Gemin6 as a novel component
  JOURNAL   J Biol Chem 277 (9), 7540-7545 (2002)
   PUBMED   11748230
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jun 6, 2021 this sequence version replaced NM_001009466.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY053516.1, FN806219.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN12840108
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-225               JAXUCZ010000006.1  20542628-20542852   c
            226-369             JAXUCZ010000006.1  20541718-20541861   c
            370-1201            JAXUCZ010000006.1  20538325-20539156   c
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..1201
                     /gene="Gemin6"
                     /note="gem (nuclear organelle) associated protein 6"
                     /db_xref="GeneID:362688"
                     /db_xref="RGD:1311168"
     exon            1..225
                     /gene="Gemin6"
                     /inference="alignment:Splign:2.1.0"
     exon            226..369
                     /gene="Gemin6"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..745
                     /gene="Gemin6"
                     /note="isoform 1 is encoded by transcript variant 1;
                     gem-associated protein 6"
                     /codon_start=1
                     /product="gem-associated protein 6 isoform 1"
                     /protein_id="NP_001009466.2"
                     /db_xref="GeneID:362688"
                     /db_xref="RGD:1311168"
                     /translation="MSEWTKKSPLEWEDYVYKEVRVIASEKEYKGWLLTTDPVSANIV
                     LVNFLEDGRLCVTGIMGHSVQTVETVSEGDHRVREKLMHLFTSADCKGYSPEDLEKKK
                     TSLKKWLEKNHIPVTEEGDTQRTLCVAGVLTIDPPYAPENCSSSNEIILSRIQDLIQG
                     HLSASQ"
     exon            370..1201
                     /gene="Gemin6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgctgggct caggcgggcc gactcaagac tgttccgtgg cgtgtgagct aagtcggact
       61 ttagtcaggc gtctcttcgg cttttccctg cattgcgcac agctctgggt atggcggcct
      121 caaggcagga cccagtcttc gagctctaga gcttcgctgg agcgtcctca gcgctttatg
      181 aggaaattgg cgcaaacccc gcggagaatc atctagaaag agtagatcta gccagctggt
      241 aaccatgagt gaatggacga agaaaagccc cttagaatgg gaggattacg tttacaaaga
      301 agtgagagtg atagccagtg agaaggagta taaaggatgg ctgctaacca cagacccagt
      361 ctctgccaac attgtcctcg tgaacttcct tgaagatggc agactatgtg tgactggaat
      421 tatgggacat tctgtgcaga cagtggaaac tgtaagcgaa ggggaccaca gagtaagaga
      481 gaagctgatg catctgttca catctgcaga ttgtaaaggg tacagccctg aggatctgga
      541 aaagaagaaa accagcctaa agaaatggct tgagaagaac cacatccctg tcactgaaga
      601 gggagacaca caaaggactc tctgtgtggc tggggttctt actatagacc caccatatgc
      661 tccagaaaat tgcagcagct ctaacgagat tattctgtcc cgaattcagg atcttattca
      721 aggccatctt tcagcttccc agtgagaggc cgcacgagga gcacactgac ttcactgttt
      781 ggttctgtat taaattcttc cagtgtaagt tgattatatt acaagacttc aaagcacatg
      841 actactatgt gtatatgcgc acattttttt ttttcttttt cttttttttc ggagctgggg
      901 accgaaccca gggccttgcg tttgctaggc aagcgctcta ccactgagct aaatccccaa
      961 ccccatatgc gtacatttta agtttttgtt taggtcaaat cagaggaagt gaaggcacca
     1021 gaacagtgtc ccttgtcctg aaaagaacac aggagagtca aatttggaag gagatttcct
     1081 tgcatatgat ttaagataaa tcaccctatt tgtgagacaa gggtgcattt tgaataggtg
     1141 taacaatgtg aaataaactt gtaaatttca atataagata ttaaagtaaa aatcagtctc
     1201 a
//
