LOCUS       NM_001109152            4419 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus glycerophosphodiester phosphodiesterase domain
            containing 5 (Gdpd5), mRNA.
ACCESSION   NM_001109152 XM_001065823 XM_574499
VERSION     NM_001109152.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4419)
  AUTHORS   Park,S., Lee,C., Sabharwal,P., Zhang,M., Meyers,C.L. and
            Sockanathan,S.
  TITLE     GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor
            cleavage of RECK
  JOURNAL   Science 339 (6117), 324-328 (2013)
   PUBMED   23329048
REFERENCE   2  (bases 1 to 4419)
  AUTHORS   Rodriguez,M., Choi,J., Park,S. and Sockanathan,S.
  TITLE     Gde2 regulates cortical neuronal identity by controlling the timing
            of cortical progenitor differentiation
  JOURNAL   Development 139 (20), 3870-3879 (2012)
   PUBMED   22951639
REFERENCE   3  (bases 1 to 4419)
  AUTHORS   Sabharwal,P., Lee,C., Park,S., Rao,M. and Sockanathan,S.
  TITLE     GDE2 regulates subtype-specific motor neuron generation through
            inhibition of Notch signaling
  JOURNAL   Neuron 71 (6), 1058-1070 (2011)
   PUBMED   21943603
REFERENCE   4  (bases 1 to 4419)
  AUTHORS   Gallazzini,M., Ferraris,J.D. and Burg,M.B.
  TITLE     GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically
            regulates the osmoprotective organic osmolyte GPC
  JOURNAL   Proc Natl Acad Sci U S A 105 (31), 11026-11031 (2008)
   PUBMED   18667693
REFERENCE   5  (bases 1 to 4419)
  AUTHORS   Yanaka,N., Nogusa,Y., Fujioka,Y., Yamashita,Y. and Kato,N.
  TITLE     Involvement of membrane protein GDE2 in retinoic acid-induced
            neurite formation in Neuro2A cells
  JOURNAL   FEBS Lett 581 (4), 712-718 (2007)
   PUBMED   17275818
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Sep 11, 2019 this sequence version replaced NM_001109152.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. This RefSeq transcript is based on
            alignments from orthologous transcripts.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.3441.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-681               JAXUCZ010000001.1  163091844-163092524
            682-767             JAXUCZ010000001.1  163097427-163097512
            768-849             JAXUCZ010000001.1  163122576-163122657
            850-1026            JAXUCZ010000001.1  163135322-163135498
            1027-1130           JAXUCZ010000001.1  163148935-163149038
            1131-1224           JAXUCZ010000001.1  163152496-163152589
            1225-1284           JAXUCZ010000001.1  163153221-163153280
            1285-1383           JAXUCZ010000001.1  163159379-163159477
            1384-1477           JAXUCZ010000001.1  163159746-163159839
            1478-1623           JAXUCZ010000001.1  163160192-163160337
            1624-1706           JAXUCZ010000001.1  163162891-163162973
            1707-1857           JAXUCZ010000001.1  163164218-163164368
            1858-2076           JAXUCZ010000001.1  163165000-163165218
            2077-2234           JAXUCZ010000001.1  163165692-163165849
            2235-2382           JAXUCZ010000001.1  163166126-163166273
            2383-2465           JAXUCZ010000001.1  163168098-163168180
            2466-2578           JAXUCZ010000001.1  163170534-163170646
            2579-4419           JAXUCZ010000001.1  163171719-163173559
FEATURES             Location/Qualifiers
     source          1..4419
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..4419
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /note="glycerophosphodiester phosphodiesterase domain
                     containing 5"
                     /db_xref="GeneID:499211"
                     /db_xref="RGD:1559673"
     exon            1..681
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            682..767
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            768..849
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            850..1026
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     CDS             910..2727
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /EC_number="3.1.4.11"
                     /codon_start=1
                     /product="glycerophosphodiester phosphodiesterase
                     domain-containing protein 5"
                     /protein_id="NP_001102622.2"
                     /db_xref="GeneID:499211"
                     /db_xref="RGD:1559673"
                     /translation="MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLW
                     FLLLVCTFSLTLTWLYFWWGVHNDYDEFNWYLYNRMGYWSDWSVPILVTTAAAFTYIA
                     GLLVLALCHIAVGQQMNLHWIHKMGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGT
                     APFLHIGALVAITALSWIVAGQFARAERSSSQLTILCTFFAVVFTFYLVPLTISSPCI
                     MEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHD
                     TTLRRTTNVEQVFPELARRPAAMLNWTSLQRLNAGQWFLKTDPFWTASSLSPSDHREV
                     ENQSICSLAELLELAKGNATLLLNLRDPPHDHPYRGSFLNITLEAVLRSGFPQHQVMW
                     LFNRQRPLVRKMAPGFQQTSGSKEAIASLRRGHIQKLNLHYTQVSHQELRDYASWNLS
                     VNLYTVNAPWLFSLLWCAGVPSVTSDNSHTLSRVPSPLWIMPPDEYCLMWVTADLISF
                     SLIIGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSD
                     ELSVCSDSSYDTYANSTVTPMGPQSAGSRAKTFTEQGGH"
     exon            1027..1130
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1224
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1284
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1383
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1477
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1478..1623
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1706
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1857
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            1858..2076
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            2077..2234
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            2235..2382
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2465
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2578
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..4419
                     /gene="Gdpd5"
                     /gene_synonym="RGD1559673"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggtagta gaggctgcgg cgcggggctg agcaagcggc gagcgcggtg ccggtaatag
       61 gaggaagtgg agcggccccc cggagctccg gagtccgctg ccgggcaggt ccgcccagat
      121 ttgcagagta agccgcgtcg ggacctgggc agacttcttc gtcttgctcc ggccgctggc
      181 gccccgcctg ccctgccctg ccctgccctg cttgtccgag ccccgcattc cgcgcctgta
      241 ctttctcagc cccgtggtcc gaacctgctg ggacgttcga gccccggcct tgatccggag
      301 ctccgagacg ggacattctc ggccccatca tactgaccca tctctgccgg agtgtcctcc
      361 gcccccgggt cggcgcaagg tggcccgggc tctcggactt gagtgtaaag gagccgggac
      421 acccaccggc ctccagctcc cggaaaacca aatcttgagc tgccttggac cgaactgctt
      481 gaaactgtac tggcgccgcc cgggtccagc gcacagtgag gggtcccaag ctggcaggac
      541 agtcgaactg aacccctgga ctggtgctgc gaaccgaagc tgccaccttt cttcgtccta
      601 ggcaaaggat ttggaggtgc ttgccccaag gcgaacacag gggtttctcc tgccacagtc
      661 tccagagagc cgaggttgca gagaggtagc atttccacac tcttcatcca ccgacaacag
      721 gtgacaccac tggagactgg gctgtggagg aaacatacgg accacagctc ttcgactgaa
      781 gtgacatcac catctctctg gataggacac ccctggagtg cagcccctag ccaccggatc
      841 ttcttccagc accagccagt ggcctccatg ggcgcttgag ggccaggcac cagggctgcg
      901 ggcacgagca tggtgagaca ccagcccctg cagtactacg agccccaact gtgcctctcg
      961 tgcctcaccg gcatctatgg ctgccgctgg aagcgctacc aacgctcaca cgatgacaca
     1021 actccgtggg aacgcctgtg gttcctgctc cttgtctgca ccttcagcct cacgctcacc
     1081 tggctctact tctggtgggg agtccacaac gactacgatg agttcaactg gtacctctac
     1141 aaccgcatgg gctactggag cgactggtct gtgcccatcc tggtgaccac agctgcggcc
     1201 ttcacataca ttgcaggact cctggtcctg gcactatgtc acatcgctgt ggggcagcag
     1261 atgaacctgc actggataca caagatgggg ctggtggtca tcttggcctc cacagtggtg
     1321 gccatgtctg cagtggccca gctatgggag gatgagtggg aggtgctgct gatctccctg
     1381 cagggcacag caccattcct gcatataggg gccctggtgg ccatcactgc gctctcttgg
     1441 atcgtggccg gacagttcgc ccgtgcagag cgctcttcct ctcagcttac aattctttgt
     1501 accttcttcg ccgtggtctt caccttctac ctggtccctc tcaccatctc ctctccctgc
     1561 atcatggaga aaaaagacct gggccccaaa cctgccctca tcggccaccg aggggctccc
     1621 atgctggctc cagaacacac actgatgtcc ttccggaagg ccctggagca gaagctgtat
     1681 gggctgcaag ctgacatcac catcagcctg gatggtgtgc cctttctcat gcatgacact
     1741 accctgaggc ggaccaccaa tgtggagcag gtgttcccgg agcttgcccg aaggcctgct
     1801 gccatgctca actggacttc tctgcagagg ctcaatgccg gccagtggtt cctcaagact
     1861 gaccccttct ggacagccag ctccctgtca ccctccgacc acagggaggt tgagaaccag
     1921 tccatctgca gcctggcaga gctcctggag ctagccaaag gcaacgctac tctgctgctc
     1981 aaccttcggg acccacccca tgatcacccg taccgtggca gcttcctcaa catcacactg
     2041 gaggccgtgc tccgttcagg ctttccacag caccaggtca tgtggctgtt taacaggcag
     2101 aggcctttgg tacggaagat ggctcctggc ttccagcaaa catctgggtc taaagaagcc
     2161 atcgccagcc tacggagagg tcacatccag aagctcaacc tccactatac tcaggtgtcc
     2221 caccaggagc tcagggacta tgcatcctgg aacctgagtg taaacctcta cactgtcaat
     2281 gccccgtggc tcttctccct gctgtggtgt gccggggtcc cctctgtcac ttccgacaac
     2341 tcccataccc tttctcgggt gccttctcca ctctggatca tgcccccaga tgagtactgc
     2401 ctcatgtggg tcactgctga cctgatctcc ttcagcctca tcattggcat cttcgtgctc
     2461 cagaagtggc gcctgggtgg tatacggagt tacaacccag agcagatcat gctgagtgcc
     2521 gccgtacgcc ggaccagccg ggatgtcagc atcatgaaag agaaactcat cttctcagag
     2581 atcagtgatg gtgtggaagt ctctgatgag ctctccgtat gttcagacag cagttacgac
     2641 acctatgcca acagcacagt cacccccatg ggccctcaaa gtgctggcag ccgtgccaag
     2701 accttcacag agcagggtgg gcattagctg aagatctgtc tacccaactt gtacccaagg
     2761 tagaatctag aagagaggaa ggactgacga cagaaacggc acctcgagtg cctgggagct
     2821 ggcacccact tgtgtgctcc cagctctttt gtctgttcca gcctctcttg catgagtggt
     2881 ggggaccagg ggagccctct ccactgaggc tggaccagga ctccagcctc tcagatgccc
     2941 ctgcaggcct ggggcttttc atccaggaaa tgagggcctg ctctccactc agtcatcctt
     3001 ggcctcccag cctggaaggt ttggtgagtc actgggctgt gccatgtgcc ccatgcaagt
     3061 ggaggacgtg gatgtccccc tgtgcccaca cctatttatc tgtctgtgct gtaagatgac
     3121 taactgttct cacccctgcc tgggggctct actcttggca cctatctcaa agcacaagga
     3181 agttcatctc aggagaaacc agtggctgcg gtggagacat gttcctccca actagcttcc
     3241 ctccaccaca ggcctctctg tccctgagaa gcagctaaag atgaccagaa tcacacactc
     3301 agggctgttc tgcctcacac ccaggtgtcc agcaggggca gaagaagcct tgaggaccag
     3361 gtgaacgaca gactgatatg acctcaggtt cccacagcag tggccacagg gcaatgggcc
     3421 acctgggcaa agcgctctgg gctcagtcaa gcatgggcct ctggccaaag ttgcctatag
     3481 tagaaggaac ctaagggcaa aaacaattaa atctgccatc gtgatgtgtg ttgtctctga
     3541 attgtcagtg gcagtttggg gaaccagcaa gcaggggttg gggtcaggtg ttggccctgg
     3601 gttttgagga tgagccattt cacagataaa agtaaaaacg actggatgtc tgagtcctac
     3661 ccttgatccg ccatgattct gggacctcag cagcccttgg attgtaaaac caatgaacac
     3721 ccttgcatta tgggaggcag gatgccaatg tgaccatcca aagtcacata ggcaaagcca
     3781 gggctactct ttttaagaag cccacatcca cactcttaac tctcatgctt aaaaatgtct
     3841 tttagggtgt ggggtggtgg cacgtgattt tattttaaat tacctttttg aattttaaga
     3901 agtatgtatt tgtatttgtg ggtatgcata ctcatgagga gcaccctcag agtgtagaag
     3961 agtgtgttga tctcctggag ctggaggtac aagcagtggt gagccacttg atagaggtgt
     4021 taggaaccga actcgggtcc tctagaacag cagccaaggt ccttaaccac tgagccttcc
     4081 ctcagccccc aaagtgtctt tctagaaaaa taaactccag tgggatgggg agatggctca
     4141 gcagttaaga accacagttc agtacccaat gccagaactc tcacagctgc ctgcaactgg
     4201 ccttcattgc acacacgtgg tatggacaca gtacaggcca aacactctac ataaaataat
     4261 ttgagtcagg gactctctgt atagcccaag ctgtcctgga attcattatg tagaccagac
     4321 tagccttgaa cagagatctg ccttcctctg attccctagt tctggggtta aaggtgtgtt
     4381 ccatcattcc tggctcttaa taaaaagcga aacaacaaa
//
