LOCUS       NM_173312               1991 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus glucosaminyl (N-acetyl) transferase 3, mucin type
            (Gcnt3), mRNA.
ACCESSION   NM_173312
VERSION     NM_173312.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Stone,E.L., Ismail,M.N., Lee,S.H., Luu,Y., Ramirez,K., Haslam,S.M.,
            Ho,S.B., Dell,A., Fukuda,M. and Marth,J.D.
  TITLE     Glycosyltransferase function in core 2-type protein O glycosylation
  JOURNAL   Mol Cell Biol 29 (13), 3770-3782 (2009)
   PUBMED   19349303
REFERENCE   2  (bases 1 to 1991)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 1991)
  AUTHORS   Zhang,T., Haws,P. and Wu,Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
REFERENCE   4  (bases 1 to 1991)
  AUTHORS   Korekane,H., Taguchi,T., Sakamoto,Y., Honke,K., Dohmae,N.,
            Salminen,H., Toivonen,S., Helin,J., Takio,K., Renkonen,O. and
            Taniguchi,N.
  TITLE     Purification and cDNA cloning of
            UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to
            Gal]beta1,6N-acetylglucosaminyltransferase from rat small
            intestine: a major carrier of dIGnT activity in rat small intestine
  JOURNAL   Glycobiology 13 (5), 387-400 (2003)
   PUBMED   12626393
  REMARK    GeneRIF: purification, cloning and sequencing of enzyme from small
            intestine; significant homology with human and virus enzyme
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB098520.1.
            
            [WARNING] On Aug 6, 2024 this sequence was replaced by NM_173312.3.
            
            On Aug 30, 2012 this sequence version replaced NM_173312.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB098520.1, CB778545.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1991              AB098520.1         2-1992
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..1991
                     /gene="Gcnt3"
                     /gene_synonym="beta-16-N-acetylglucosaminyltransferase;
                     dI/C2/C4GnT"
                     /note="glucosaminyl (N-acetyl) transferase 3, mucin type"
                     /db_xref="GeneID:286976"
                     /db_xref="RGD:631333"
     exon            1..164
                     /gene="Gcnt3"
                     /gene_synonym="beta-16-N-acetylglucosaminyltransferase;
                     dI/C2/C4GnT"
                     /inference="alignment:Splign:2.1.0"
     exon            165..1963
                     /gene="Gcnt3"
                     /gene_synonym="beta-16-N-acetylglucosaminyltransferase;
                     dI/C2/C4GnT"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..1531
                     /gene="Gcnt3"
                     /gene_synonym="beta-16-N-acetylglucosaminyltransferase;
                     dI/C2/C4GnT"
                     /EC_number="2.4.1.102"
                     /EC_number="2.4.1.150"
                     /EC_number="2.4.1.148"
                     /note="dIGnT; C2GnT-M; C2GnT-mucin type;
                     beta-1,6-N-acetylglucosaminyltransferase"
                     /codon_start=1
                     /product="beta-1,3-galactosyl-O-glycosyl-glycoprotein
                     beta-1,6-N-acetylglucosaminyltransferase 3"
                     /protein_id="NP_775434.1"
                     /db_xref="GeneID:286976"
                     /db_xref="RGD:631333"
                     /translation="MVSWRRFCWHYHGWTLGCYMLLAIIALKLSLRLKCDFDVMDLDS
                     KEFQSQYCRDLLYKTLELPAKSSINCSGVIRGEQKAVTQALLNNLELKRKRQSFTEAD
                     YLSMTADCEHFKTQRKFIQVPLSKEEANFPIAYSMVIHEKIENFERLLRAVYTPQNIY
                     CVHVDQKSSETFQQAVRAIVSCFPNVFIANKLVSVVYASWSRVQADLNCMEDLLQSPV
                     PWEYLLNTCGTDFPIKTNAEMVKALKLLNGQNSMESEVPPPHKTFRWKYHYEVADTLY
                     RTSKEKTPPPNNITMFTGNAYMVASRDFIEHVLSNSKARQLIEWVKDTYSPDEHLWAT
                     LQRASWMPGSDPLHPKFDLSDMRSIARLTKWQDHEGDIENGAPYTSCSGIHQRAICVY
                     GSGDLHWILQNHHLLANKFDPKVDDNVLQCLEEYLRHKAIYGTEL"
ORIGIN      
        1 gctctctcct ttgcataggt ctaacaggag cgttgagctc cttggagtct gggaggtaag
       61 aaggcaaagt gttaatttgt acctcgtaga accaaactaa ccttcactcc acagactcac
      121 aacgttggag agaactcccc taagcagcca agaaggtatc aaagagagcc cacccactcc
      181 tctgctgggc gaggcttgat ggttcccacc tgtgaagatg gtttcatgga ggaggttctg
      241 ttggcactat catgggtgga ccctgggctg ctacatgctg ctggctatca ttgccctgaa
      301 actgtccctc agattgaagt gtgatttcga tgtcatggat ctggactcaa aggaatttca
      361 aagccagtac tgcagggacc tcctgtacaa gaccctggag ctgccagcaa agagttccat
      421 caactgttca ggggtcatcc gaggggaaca gaaagcggtg acccaggctc tgctgaataa
      481 cctggaactt aagaggaagc ggcagtcctt cacagaggct gactacctta gcatgacggc
      541 agactgtgag cacttcaaga cccagaggaa gtttatacag gtcccactga gcaaagaaga
      601 ggccaacttc cccattgcgt actccatggt gattcatgag aagattgaga actttgaaag
      661 gctgctgcga gctgtgtaca cccctcagaa catatactgt gtccatgtgg accagaagtc
      721 ttcagaaact tttcagcagg cagtcagggc cattgtgtca tgcttcccca atgtcttcat
      781 agctaataag ctggtgtcag tggtctatgc ctcctggtcc agagtgcagg ctgatctgaa
      841 ctgcatggaa gacttgctcc agagccccgt gccgtgggag tacctcctga acacctgtgg
      901 gacagacttc cccatcaaaa ccaatgccga gatggtcaag gccctcaagc tactgaatgg
      961 gcagaacagc atggagtcag aggtaccacc tccacataaa acgttccgtt ggaaatacca
     1021 ctatgaggtg gccgacacac tatacagaac cagcaaggag aagaccccgc cccctaacaa
     1081 cataaccatg ttcactggca atgcctacat ggtggcttct cgagacttca ttgaacatgt
     1141 attaagtaac tcaaaagccc ggcaactgat cgaatgggta aaagacactt acagtcctga
     1201 tgagcacctt tgggccaccc tccagcgtgc ctcatggatg cctggatcag atcccttgca
     1261 ccccaaattt gacctatcag acatgagatc cattgcaaga ctaaccaagt ggcaggacca
     1321 tgagggagac attgagaatg gggcgcctta tacgtcttgc tcaggaatcc accagcgggc
     1381 tatctgtgtt tacgggtcag gggacctgca ctggatactt cagaaccatc acctcttggc
     1441 caacaagttt gatccaaagg tggatgacaa tgttcttcag tgtctagaag aatatttacg
     1501 tcacaaagcc atctatggga ccgagttatg agactcactg caagatgatt gttacctgtg
     1561 tggcaggaaa atgccaggac ctactggggc aatgtggggt aggcagctgg ggctcaagac
     1621 tccatgtgtc cctcaggatg aggggctgca attggacagt gggtaagtag acctctgccc
     1681 cttgtgagct gttgctggtg aatgtggccg ttctccagtt ctttccccaa caggctttct
     1741 ttagcttcct cacagagcta gaaaaagaaa tactgttact tgggaaagtg acggagggga
     1801 catgtggcca gggactctgg attctggctg aaggcttcct gtcaggttct ctacagagac
     1861 tttgtttcaa attcccctgg cttagtcttg ggaggggaac tttagtgcaa agaaccctcc
     1921 tcttttgtat tgttaattta aaataaatag cttctaaacc aaaaaaaaaa aaaaaaaaaa
     1981 aaaaaaaaaa a
//
