LOCUS       NM_022276               5005 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus glucosaminyl (N-acetyl) transferase 1 (Gcnt1),
            mRNA.
ACCESSION   NM_022276 XM_346572
VERSION     NM_022276.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5005)
  AUTHORS   Ali,M.F., Chachadi,V.B., Petrosyan,A. and Cheng,P.W.
  TITLE     Golgi phosphoprotein 3 determines cell binding properties under
            dynamic flow by controlling Golgi localization of core 2
            N-acetylglucosaminyltransferase 1
  JOURNAL   J Biol Chem 287 (47), 39564-39577 (2012)
   PUBMED   23027862
REFERENCE   2  (bases 1 to 5005)
  AUTHORS   Stone,E.L., Ismail,M.N., Lee,S.H., Luu,Y., Ramirez,K., Haslam,S.M.,
            Ho,S.B., Dell,A., Fukuda,M. and Marth,J.D.
  TITLE     Glycosyltransferase function in core 2-type protein O glycosylation
  JOURNAL   Mol Cell Biol 29 (13), 3770-3782 (2009)
   PUBMED   19349303
REFERENCE   3  (bases 1 to 5005)
  AUTHORS   VanderElst,I.E. and Datti,A.
  TITLE     beta1,6 N-acetylglucosaminyltransferase (core 2 GlcNAc-T)
            expression in normal rat tissues and different cell lines: evidence
            for complex mechanisms of regulation
  JOURNAL   Glycobiology 8 (7), 731-740 (1998)
   PUBMED   9621114
REFERENCE   4  (bases 1 to 5005)
  AUTHORS   Nishio,Y., Warren,C.E., Buczek-Thomas,J.A., Rulfs,J., Koya,D.,
            Aiello,L.P., Feener,E.P., Miller,T.B. Jr., Dennis,J.W. and
            King,G.L.
  TITLE     Identification and characterization of a gene regulating enzymatic
            glycosylation which is induced by diabetes and hyperglycemia
            specifically in rat cardiac tissue
  JOURNAL   J Clin Invest 96 (4), 1759-1767 (1995)
   PUBMED   7560067
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_022276.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: S79797.1, SRR26360194.2345792.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5005              JAXUCZ010000001.1  224145104-224150108 c
FEATURES             Location/Qualifiers
     source          1..5005
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..5005
                     /gene="Gcnt1"
                     /gene_synonym="core 2 GlcNAc-T"
                     /note="glucosaminyl (N-acetyl) transferase 1"
                     /db_xref="GeneID:64043"
                     /db_xref="RGD:621370"
     exon            1..5005
                     /gene="Gcnt1"
                     /gene_synonym="core 2 GlcNAc-T"
                     /inference="alignment:Splign:2.1.0"
     CDS             798..2084
                     /gene="Gcnt1"
                     /gene_synonym="core 2 GlcNAc-T"
                     /EC_number="2.4.1.102"
                     /note="beta1,6 N-acetylglucosaminyltransferase;
                     glucosaminyl transferase 1, core 2; enzymatic
                     glycosylation-regulating; glucosaminyl (N-acetyl)
                     transferase 1, core 2
                     (beta-1,6-N-acetylglucosaminyltransferase)"
                     /codon_start=1
                     /product="beta-1,3-galactosyl-O-glycosyl-glycoprotein
                     beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="NP_071612.1"
                     /db_xref="GeneID:64043"
                     /db_xref="RGD:621370"
                     /translation="MLRNLFRRRLFSYPTKYYFMVLVLSLITFSVVRIHQKPEFVSVS
                     HLELSGDDPNSNVNCTKVLQGDPEEIQKVKLEILTVQFKKRPRRTPHDYINMTRDCAS
                     FIRTRKYIMEPLTKEEVGFPIAYSIVVHHKIDMLDRLLRAIYMPQNFYCIHVDRKAEE
                     SFLAAVQGIASCFDNVFVASQLESVVYASWSRVKADLNCMKDLYRMNANWKYLINLCG
                     MDFPIKTNLEIVRKLKSFTGENSLETEKMPPNKEERWKKRYTVVDGKLTNTGVVKAQP
                     PLKTPLFSGSAYFVVTREYVGYVLENKNIQKFMEWAQDTYSPDEFLWATIQRIPEVPG
                     SLPSSHKYDLSDMNAVARFVKWQYFEGDVSNGAPYPPCSGVHVRSVCVFGVGDLSWML
                     RKHHFFANKFDMDVDPFALQCLEEHLRHKALETLER"
ORIGIN      
        1 agttcagcaa ggccttttaa gtccattttg aatactcagc agaatgaatt gtcttgcttc
       61 cagatgtgga tcacattcac gattgttctt aaccttttct ctaagtgagt caccgtccta
      121 agtcagcaaa aggcagaatg gatctgaccc ttgcaagcgt cttctgcctg ttgatgtcac
      181 caggaggaac ttggtgacga tatgaagata gaggtgctga ttcttaggac ctgcagagtc
      241 ctgtgctcct gtatagccat aggtccagct tttgagacag tttctttttt tatagtcctg
      301 gttgtcctgg aactcactac atagaccaga cttgcctctg ccccctaggt gctgggataa
      361 aggtgtgtgt tacctcgtgg gatctcagat gtctatggta ggatatttta ggacgtcctt
      421 gttttaggtt cggtgcctat ttttaccccc agtttccggc ttcaatttga gaacaatggg
      481 tcttctatga agcgatctct attctctaat taagacaacc tctttttttt tttttttttc
      541 taaataaaat ctggtctcat agcaaagggg atagttttga gcctgagaag acgctgtaaa
      601 cagttgcatt tactaagtgt gttctttgct atattttctt ttgcttttag ctctgtcctg
      661 tgtggtgctc tattgtccct cttacaaact ggcaacttat ctggccacaa cagaaggaca
      721 ctggaggaaa cctcactggc gtccaaggcc tagaagattg ttccaccacc ccagggagcc
      781 tctgagtgtt ctttgaaatg ctgagaaact tgtttcggag gagacttttt tcttatccta
      841 caaaatacta cttcatggtt cttgttctgt ctctaattac cttctctgtt gtaagaattc
      901 atcagaagcc tgaatttgtt agtgtcagtc acttggagct ttctggagat gatcccaata
      961 gcaatgttaa ttgcaccaaa gttttacagg gtgacccaga agaaatccag aaggtgaagc
     1021 ttgagatact aacagtgcaa ttcaagaagc gtccgaggcg gacaccgcat gactatataa
     1081 acatgacccg ggactgcgcc tccttcatca ggacacgcaa atatattatg gagcccctta
     1141 ctaaagaaga ggttggcttt ccaattgcat attccatagt ggttcatcat aagattgaca
     1201 tgcttgacag gctcctgagg gccatctata tgcctcagaa tttctactgc attcacgtgg
     1261 acagaaaagc agaggaatcc tttttagccg cggtgcaggg cattgcatcc tgctttgata
     1321 atgtctttgt ggccagccag ttggagagtg ttgtatacgc ctcctggagt cgggttaagg
     1381 ctgacctcaa ctgcatgaag gacctgtaca gaatgaatgc aaactggaag tacttgatca
     1441 atctttgtgg tatggatttc cctattaaaa ccaacctgga aattgtcagg aagctcaagt
     1501 ccttcacagg ggaaaacagc ctggaaactg agaagatgcc tcccaacaag gaagagaggt
     1561 ggaaaaaacg atacacggtt gtggacggga agctgacaaa cactggagtt gtcaaggcgc
     1621 agcctccact caaaactcct ctcttttcag gcagcgccta tttcgtggtc actagggaat
     1681 atgtaggcta tgtgctggaa aataaaaata ttcaaaagtt catggaatgg gcacaggaca
     1741 catacagccc ggatgagttc ctctgggcca ccatccaaag gatccctgaa gtccctggtt
     1801 ctctcccctc aagccataag tatgacttgt ctgacatgaa tgctgtcgct aggtttgtca
     1861 agtggcaata cttcgaaggc gatgtttcca atggcgcgcc ttatccaccg tgcagtggag
     1921 tccatgtgcg ctctgtgtgc gtctttggag ttggtgactt gagctggatg ctgcgcaaac
     1981 accacttttt tgccaataag tttgacatgg atgtggatcc ctttgccctc cagtgtttgg
     2041 aagaacatct gaggcataaa gccctggaga ccttagaacg ctaagcactg ttggcagtcc
     2101 tggggaagat aaagacacac aagctgtacc ctcatctgct tcccttctct cctatcgggt
     2161 cctcctattg gggcgatgac ttcaaagtct tcctgtcagg gaagctgcgt ggatcctaca
     2221 gaacatagct acaagagaga ttgatacatt gcgtgctcta gagtaaatgc aaggacggag
     2281 ttaggatggc tggaggctgg ggaagatttt gtggacagag aggctctggg taattgagaa
     2341 agaggccaat gaaaagcgtc agccttgaga actaatcaaa gaacccaggt acttaatcta
     2401 aatgagattt gatttgtgcc aaaagtcgct tgaaaacgtt aagcataatt ttcttgacag
     2461 gaataaattt gtagcaacaa ccaatcacag agataggatt tctcttgtat gttttttgga
     2521 acagacgttt ggtcttactc taacttatcc ttgtaaataa tttccttcct gctgtgattt
     2581 tgggtagggg gtctcaggga gcttaaaata tgtttggcat gaatagctct gtcttaattt
     2641 tcgcttataa ctacacatac atgttttcaa aagcaagagg acagtttcta gttccccgac
     2701 ttctttgagt attcctttat taaaaaagaa ccagctgggt gtgtcacctg tgcctgtgaa
     2761 gcagggcagt tgtttaatct cgagtgatat cggccaagct ggacaacaaa acaagaagtt
     2821 gtctctttaa aaaggagaag aagatcaact cgattttaca aatacatagt tttttcctta
     2881 tcttgtcttc ccagactgct tatactgtca agctgcacac atgtcgctgt ttaaggaccc
     2941 tatatctgtg ttttgggtct tcgatgggaa ccagtcacct gtaactagtg caaaaaatta
     3001 gggagggtga agtaggcatc caaggggaga tgggaatcta ctaaggctgt tgctaagccc
     3061 ctggcacaag ttttgtccca agaaattaag gtttctgcct actggatccg attgtgtctc
     3121 atgtggccac attctggcct tgagtattca tgttatctgc ccattggctt ttcttaacct
     3181 gccagtttcc tcctctctca cggccttgat gagggggaaa gaagtagaga aaaatgcctg
     3241 tgtccacact aagtgtttga aaagagttgt ggtatcataa tatgttttca ccaaaagaca
     3301 aacggtctag ggtttcttca actctttctc ttgtctctag tgcagggttg tttgtttgtt
     3361 ttctcttaat atttagctaa atctaaacag gattctagtg aaatgtgaag acttgccatt
     3421 tgattttaaa taagaatcat taccacgtac tttcatttac tttcataatc cagaagaaaa
     3481 tcatagtatc agacagtttt aaggtattca gcagagaaag tgtgttttct gcctcaaagc
     3541 tatgaagtgt tttaggatca ggagataagc tgggttttgt gttggaccaa tagaaatgcg
     3601 tttgccacag ggtcaccagc gatgatggcg gtgcagctga cgccatctac acaatctggc
     3661 ttctgctttc ttttttaggt ttgtaaccaa gatttgtcca atggtccttt tagtagaaag
     3721 gcttttactt atgagacagg gcatctttta aatctaaaac cagtggtacc tggtgacata
     3781 tcatttgggt aagccgctgt gacttcagca gattttcttt ttccatcttg aaagtgcagg
     3841 gttaaagcag tagtcttggg atccaacaaa cggcaacccc aacctggggt agccggtggt
     3901 caacacatcc agcccgattt gctttatact caatgagctc ttgaactttg caaaactgga
     3961 aatttttttt ttaattacaa gtactttttt tcttaaaaaa aaatcaacta tttgatgtta
     4021 ttcatctaaa cactcttaat tgtagtggtg ctccatttca gttaaatggc aagtttgagg
     4081 attgtttatt tttattgttt gcccctctac aggagtaaaa ctaggattct agaattccag
     4141 agcctcaagt caatgctgtg aagcctccta cttcctgtta cctcaccttt gtagcattgc
     4201 acttgttcaa aggatgctgt agcgcccaat gcctgccaca gggcttgtac agtgtctgtt
     4261 tactgtgact caatggattt tatttttgga gcttttcaat atgacttaaa gcaaaagaaa
     4321 ttcatacggt ggggtaaata attcaaagaa ctaaaaaggg gacttggaaa tgaatacata
     4381 agactccaga agagtacaat tgcagctcat ttggagagat aggctttgtt catgttgaag
     4441 tcatgtttct agtaaacact aattttaatg ctatccttga ggtttcttat agacattttt
     4501 tttttttttt tttttttttg gagctgggga ctgaacccag ggcaagcgct ctaccgctga
     4561 gctaaatccc caacccctta tagagaattt tcagcaatca cattcacaaa taaaatggga
     4621 ttctagttac taagtcaatc aagattatat gtatcatttg ttagaaataa gttaatttaa
     4681 aaatattagt ttatagtcaa ttgcctaggt tcttctgatg ctgaggttta aaaaaacaaa
     4741 acaaaaaaag atttcacttt gaaacctggg aatattatta tttctaaaca tgtgtttgtg
     4801 tcgttcatct agtacagttc atttaagtga ctttatttcc tcttctcatg attttagttg
     4861 gaagaggctg gctgggtagg gtagacggaa ctggatgttt ttagttgctt aaataattat
     4921 tgtcatgaag tatataatgc aaaactattt atgtttttga atgaattggt catatcacca
     4981 ataaaatcag ttgttgagaa accaa
//
