LOCUS       NM_001107633            6526 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus GRIP and coiled-coil domain containing 2 (Gcc2),
            mRNA.
ACCESSION   NM_001107633 XM_001053446 XM_228197
VERSION     NM_001107633.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6526)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 6526)
  AUTHORS   Burguete,A.S., Fenn,T.D., Brunger,A.T. and Pfeffer,S.R.
  TITLE     Rab and Arl GTPase family members cooperate in the localization of
            the golgin GCC185
  JOURNAL   Cell 132 (2), 286-298 (2008)
   PUBMED   18243103
REFERENCE   3  (bases 1 to 6526)
  AUTHORS   Efimov,A., Kharitonov,A., Efimova,N., Loncarek,J., Miller,P.M.,
            Andreyeva,N., Gleeson,P., Galjart,N., Maia,A.R., McLeod,I.X.,
            Yates,J.R. 3rd, Maiato,H., Khodjakov,A., Akhmanova,A. and
            Kaverina,I.
  TITLE     Asymmetric CLASP-dependent nucleation of noncentrosomal
            microtubules at the trans-Golgi network
  JOURNAL   Dev Cell 12 (6), 917-930 (2007)
   PUBMED   17543864
REFERENCE   4  (bases 1 to 6526)
  AUTHORS   Derby,M.C., Lieu,Z.Z., Brown,D., Stow,J.L., Goud,B. and
            Gleeson,P.A.
  TITLE     The trans-Golgi network golgin, GCC185, is required for
            endosome-to-Golgi transport and maintenance of Golgi structure
  JOURNAL   Traffic 8 (6), 758-773 (2007)
   PUBMED   17488291
REFERENCE   5  (bases 1 to 6526)
  AUTHORS   Reddy,J.V., Burguete,A.S., Sridevi,K., Ganley,I.G., Nottingham,R.M.
            and Pfeffer,S.R.
  TITLE     A functional role for the GCC185 golgin in mannose 6-phosphate
            receptor recycling
  JOURNAL   Mol Biol Cell 17 (10), 4353-4363 (2006)
   PUBMED   16885419
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474016.2.
            
            [WARNING] On Nov 15, 2024 this sequence was replaced by
            NM_001107633.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_228197.4, XM_001053446.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132285 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..6526
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..6526
                     /gene="Gcc2"
                     /note="GRIP and coiled-coil domain containing 2"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
     exon            1..67
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..5101
                     /gene="Gcc2"
                     /note="185 kDa Golgi coiled-coil protein; LIM and
                     senescent cell antigen-like domains 1"
                     /codon_start=1
                     /product="GRIP and coiled-coil domain-containing protein
                     2"
                     /protein_id="NP_001101103.1"
                     /db_xref="GeneID:309798"
                     /db_xref="RGD:1305732"
                     /translation="MEDSAQDAVTAAPSGTPKSKLETLPREDLIKFAKKQMMLLQKAK
                     ARCTELDKEVEELKSKPVDGGTDDMIKVLTERLDALLLEKAETEQQCLCLKKENIKMK
                     QEVEDSVTKLEETQKEFEQSHRNYVREMESVKNELIAVHSEHSKEKAALQRDLEGAVH
                     RQAELLEQLKSQSDSEDNVKKLQEEIQNITAAFEEQTSCLQKQLEATSDEKQQEIIHL
                     QKVIEDNAQHYQKDINTFQEEIVQLRATHKEEVNELMSQMETLAKEHEAAVNKLKENR
                     VTLCETSETIPENYQCESESLNEDTSDASQENQKCSVALQEDPFAEHTVYDKVRQLED
                     SLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQ
                     SYVVEKLKYEREDLNRQLCCTVEQHNKEIQRLQEHHQKEISELSETFMSGSEKEKLAL
                     MFEIQGLKEQCENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQQA
                     SDVHELQQKLRTAFNEKDALLETINRLQGENEKLLSQELVSELESTMKNLKADNSMYL
                     ASLGQKDTLLQELEAKISSLAEEKDDFISKIKTSREEIDDLHQKWEREQKLSVELREA
                     AEQAAQHNSELRQRVSELTGKLDEILREKSQNDQNIMVQMKTMTEDQEALSSKIKSLY
                     EENNRLHSEKVQLSRDLEALQSQQDFAYKEHVAEFEKKLQLMVEERDDLNKLLENEQL
                     QKSFVKTQLYEFLKQMRPSILEDNEEEDVVTVLKAVGESLVTVKEEKHNLVFEYDARV
                     LELERRIKCLQEESVVQCEELRALVRDSEQEKILLRKELDEVTSTKEALQCDILEMKN
                     TNEKTSLENQTLSTRVEELSRSLHSKNEVHNEKDLVIEHENLRLSLEQRESELQDVRA
                     ELMLLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEKISKIKLVAVRAKKEL
                     DSNRKEAQTLRDELESVQSEKDRLSASMKEFIQGAESYKNLLLEYDKQSEQLDVEKER
                     ANNFEHHIEDLTKQLRDSTCQYEKLTSDNEDLLARIETLQANARLLEAQILEVQRAKG
                     VVEKELEAEKLQKEQKIKEHVSTTNELEELQLQFQKEKKQLQKTMQELELVKKDAQQT
                     TLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEMKIQKQKQETLQEEMTSLQSSVQH
                     YEEKNAQIKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKIQLAEMT
                     SEKHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRTAKAEQAAVTSEFENYKVRVHN
                     VLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQNSLQISVSEFQTLQSEHD
                     TLLERHNRMLQETVTKEAELREKLCSAQSENTMLKSEHAQTMCQLTSQNEALRNSFRD
                     QVRHLQDEHRKTVETLQHQLSKVETQLFQLKSEPPTKSPASSHQPSKSLRERRTTDLP
                     LLDMHTVTREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDSKLERLTEASLWHTEFT
                     KEELAEKLSSTTKSADHLNGLLRETEATNAILMEQIKLLKSEIRRLERNQEREKSVAN
                     LEYLKNVLLRFIFLKPGSERERLLPVIDTMLQLSPEEKGKLATVAQGEEESASRSSGW
                     ASYLHSWSGLR"
     exon            68..121
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            122..206
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            207..274
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            275..379
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            380..2821
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2822..2894
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2895..2995
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            2996..3094
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3095..3214
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3215..3379
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3380..3484
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3485..3647
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3648..3748
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3749..3826
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3827..3964
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            3965..4086
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4087..4263
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4264..4481
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4482..4676
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4677..4828
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            4829..5030
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
     exon            5031..6526
                     /gene="Gcc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcagaggcg gagtacctag gacgcctgaa aaggccgagg tggccgcggg tcgctgccac
       61 gatggaggat tctgctcaag atgctgtgac tgcagcaccc tccgggaccc cgaaatccaa
      121 gctagaaaca ttgcccagag aagatctcat caagtttgcc aagaagcaga tgatgctcct
      181 acagaaagcc aaagcaaggt gtacagaatt agacaaagaa gttgaagagc tcaaatcaaa
      241 acctgttgac ggaggaactg atgatatgat taaggtgcta actgaacgct tggatgctct
      301 tcttctggaa aaagcagaga ctgaacaaca gtgtctgtgt ctcaaaaaag aaaatattaa
      361 aatgaagcaa gaggttgagg attctgtaac taaactggaa gagacacaaa aagagtttga
      421 acaatcacat agaaactacg taagagaaat ggaaagtgtt aaaaatgaac tgatagcagt
      481 acactcagag cacagcaaag aaaaggctgc cttacaaaga gacctggagg gagcagtcca
      541 taggcaagca gagctgttag aacagctcaa gtctcagagc gactctgaag ataatgttaa
      601 aaaactacag gaagagattc agaacattac agcagcattt gaggaacaaa cgtcatgtct
      661 acaaaagcaa ttagaagcta ccagtgatga aaaacagcaa gagattattc atctccagaa
      721 agtcattgag gacaacgctc agcactacca aaaagatatt aatactttcc aagaagagat
      781 tgtgcagctg agagctacac acaaagaaga agttaatgag ctgatgtctc aaatggaaac
      841 attagctaaa gaacatgagg cagcagtaaa taagctaaaa gagaacagag tgacactgtg
      901 tgagacaagt gagaccattc cagagaatta ccaatgtgaa tcagaaagct taaatgaaga
      961 cacctcagat gcaagccagg agaatcaaaa atgctctgtg gccttacagg aagatccttt
     1021 tgcagaacat acagtgtatg ataaagtcag acaattggaa gattcattaa aagaactgga
     1081 atctcaacat agtatcttaa aagatgaagt gacttatatg aataatctca agttaaaact
     1141 tgaaatggat gcccagcata taaaggatga gtttttccat gaaagagaag acttggagtt
     1201 taaaattaat gaactgttgc tggccaaaga agaacagagc tacgtagtag aaaaattaaa
     1261 atatgagcga gaagatttaa ataggcagct ttgctgtact gtggaacaac ataacaaaga
     1321 aatacagcgt cttcaggagc accatcagaa agaaatctct gaactaagtg agacatttat
     1381 gtcaggttca gaaaaagaaa agttagcatt aatgtttgaa atacagggac ttaaggaaca
     1441 gtgtgaaaat ctacaacatg aaaagcaaga ggtagttcta aattatgaga gtttacgaga
     1501 gatgatggaa attttacaaa cggaacttgg agaatctgct ggaaaaataa gtcaagagtt
     1561 tgaaacaatg aagcaacagc aagcatctga tgttcatgag cttcagcaga agctaagaac
     1621 tgcttttaac gaaaaagacg ctcttcttga aactataaat cgcctacaag gagaaaatga
     1681 aaaattatta tcacaagaat tggtatcaga actcgaaagt accatgaaga accttaaggc
     1741 agataatagc atgtacttag ccagccttgg tcaaaaagat accctgttac aagaattaga
     1801 agcaaagata agttctcttg ctgaagaaaa agatgatttt ataagtaaaa tcaaaacttc
     1861 ccgtgaagag atagatgatc tccatcagaa atgggaaagg gaacagaaac tgtctgtaga
     1921 actcagggaa gcagcagagc aagccgccca gcacaacagt gaactgagac aaagagtaag
     1981 tgaattaaca ggaaaactag atgaaatatt aagagaaaag agtcaaaatg accaaaacat
     2041 tatggttcaa atgaaaacca tgacagaaga ccaagaagca ttgtcatcta aaatcaagtc
     2101 tctttatgag gaaaacaata gactgcattc tgaaaaggtc cagttgagta gagatttaga
     2161 agctcttcag tctcaacaag attttgccta taaagagcat gttgctgaat tcgaaaagaa
     2221 actccagtta atggttgaag aacgagatga tttaaataaa ctgcttgaaa atgagcaact
     2281 tcagaagtca tttgtcaaaa ctcagttgta cgagtttctt aagcaaatga ggccaagcat
     2341 tttagaagat aatgaagagg aagatgttgt cacagttcta aaagctgtgg gtgaatcctt
     2401 agtgacagta aaggaagaaa agcataactt agtctttgaa tatgatgcga gagtattaga
     2461 attagaaagg aggattaagt gccttcaaga ggagagtgta gttcagtgtg aagaactaag
     2521 ggctttagta agagactctg aacaagagaa aattctccta agaaaagaat tagatgaagt
     2581 cacatcaaca aaagaggccc tgcagtgtga tattctagaa atgaagaata ctaatgaaaa
     2641 aacaagcctt gaaaatcaga ctctttcaac tcgggttgaa gaattatcgc ggtcattaca
     2701 cagcaaaaat gaagtccata atgaaaagga tcttgtcata gaacatgaaa acctgaggct
     2761 atcgcttgag cagagggagt ctgagctaca agatgtgaga gcagaattga tgctgctgaa
     2821 ggattcctta gagaaatcgc cttctgtaaa aaatgatcaa ctttcattgg taaaagagct
     2881 ggaagaaaaa atagaaagtc tggaaaaaga atccaaagac aaggatgaga aaatcagtaa
     2941 gataaaacta gtcgctgtga gagcaaagaa agaactagat tctaacagga aagaggccca
     3001 gacactacgg gacgaactcg agtccgtaca gtcagaaaag gaccgcttat ctgcttctat
     3061 gaaggagttt atccaaggag cagaaagcta taagaatctt ctgttagaat atgacaagca
     3121 gtcagaacag ctggatgtgg aaaaagaacg tgctaataat tttgaacatc acatagaaga
     3181 ccttaccaaa caattaagag attcgacttg ccagtatgaa aaactaactt ccgacaatga
     3241 ggatctcctg gctcgaattg agaccctgca ggctaatgcc aggttattag aagcacagat
     3301 cttagaggtc cagagagcca aaggagtagt agaaaaagaa ctggaagctg aaaaacttca
     3361 gaaagagcag aaaattaagg aacatgtcag tactacaaat gagcttgaag aacttcaact
     3421 ccaatttcaa aaggaaaaga agcagcttca gaaaacgatg caagaattag aactggttaa
     3481 aaaggatgcc caacagacca cgttgatgaa tatggaaata gcagattacg aacgtttgat
     3541 gaaagaatta aatcaaaagt taacaaataa aaacagtaag atagaagatt tggagcaaga
     3601 aatgaaaatt cagaaacaga aacaagaaac cctacaagaa gaaatgactt ccctgcagtc
     3661 ttcagtacag cactacgaag aaaagaacgc ccaaatcaag cagctgcttg tgaaaaccaa
     3721 aaaggaactg gcagatgcaa agcaagcaga aactgatcac ttactactcc aggcgtcttt
     3781 aaagggcgag ctggaagcaa gccagcagca agtagaagtc tataaaattc agctagctga
     3841 gatgacatct gagaaacaca aaatccatga gcacctgaag acttctgcgg aacagcacca
     3901 gcgcacacta agtgcatacc agcagagggt ggtggccctg caggaagaga gccgcactgc
     3961 caaggcagag caagctgctg tcacctctga atttgagaac tacaaagtcc gggttcataa
     4021 cgttctaaaa caacagaaaa ataaatctgt gtctcaggct gaaactgagg gagctaaaca
     4081 agaaagggaa cacctggaaa tgctgattga ccaactgaaa atcaagttac aggacagcca
     4141 aaacagctta caaatcagtg tgtcagagtt ccagacactg cagtctgagc atgacactct
     4201 gctagagagg cacaaccgga tgctgcagga aactgtgacc aaagaggcgg aacttcggga
     4261 aaagttatgt tcagctcaat ctgagaacac catgttgaag tctgaacacg cccagacaat
     4321 gtgtcagctg acatcccaga atgaggccct ccgtaacagc ttccgagacc aagttcgaca
     4381 cttgcaggat gagcacagaa agacagtgga gaccttgcag caccagctct ccaaggtgga
     4441 aactcagctc ttccagctca agagtgagcc acccacaaaa agccctgctt cttcccatca
     4501 accttcaaaa agcctccgag aaagacggac cacagacctc ccccttctgg acatgcacac
     4561 tgtgacccga gaggaggggg aagggatgga gacaactgac agtgagtctg tgtcttcggc
     4621 cggcacacac attcagtcct tggagcagct ccttagctct cctgacagca agcttgaacg
     4681 tcttacagag gcctccttat ggcatacaga atttaccaaa gaagaattgg ctgagaagct
     4741 cagttccacc acgaagagtg cagatcactt aaatggcctg cttcgggaga cagaggctac
     4801 caacgccatc cttatggagc aaattaagct tctcaaaagt gaaataagaa gactggaaag
     4861 aaaccaagag cgggagaagt ctgtggctaa cctggagtac ttgaagaatg tcctactgcg
     4921 gttcattttc ctgaagccgg gtagtgaaag agagaggctt cttcctgtga tagacacgat
     4981 gctgcagctc agccctgaag aaaagggaaa gcttgccaca gttgctcaag gtgaggaaga
     5041 aagtgcctct cgttcctctg gatgggcatc ctaccttcat agctggtctg gactgcgata
     5101 ggttgacaga aagaagattc tttagtgatg caacagaact cctttggaaa agctgggtat
     5161 catttgatca tgaagtgtgc atctctgttc acatcccctg atgattgtac atatgtatag
     5221 cccatgtata tagaatctca tcttgtagta aaaggacatc agcttgaagt agtggtacca
     5281 attgttcatg gtcctctaac tcagcatgtg gcctcatggt ctctgtgatc tccacccaca
     5341 gaggaaacgg ttcattcctg cactctggaa ccccaggaga cactcatttc taagtagtat
     5401 tgtgaatttt gatattgaac taaattttgg taccaaacca actggggaat ttaatctttt
     5461 aaaataatgt ttcaagattg aggaaatgct ttattgataa ggttgacatg tttattaaaa
     5521 gattatgaag taaatatgct atggtttaat tatgaggcta acttaaattg caattcagtc
     5581 agttacttta aaataaacct ccctcccatt tgtaattttc aaaattggcc ctagtcctgg
     5641 taatgtgaca ctgacagaat aggtgggctc cacctcagct gatgtgttct gtggtgtctc
     5701 caggcttgtt tgctgccact cataagccat gagtctcttt tgagaattcc ctacatctca
     5761 aaacagtgac tgtcttactc agcattaaat ctacatgtga acctggtgct tccagtattg
     5821 ttcaagtatt cttatttcct aagcaggacc ccagagggct cagaccctct attggtgaac
     5881 aagcctagct gggggagtgt ctctgtcctt atgtctctgg aaatactata ttgactagat
     5941 taaaattgtg ctcttaaatc agatttgggg gttatatttt aatatgtaat ttgttaatga
     6001 atagtgctgt ctggagtctt aagcttacgt ttattctcca gttgtcagtc tcagcttgaa
     6061 actgtccttt agtcactatg aatattggtt tccaacctgg tttgactgaa atttactgct
     6121 gacatgttga gtttgttctc ttaaagctgt ttgactctca gtgttcgctc tacctgtgtt
     6181 agaacagacc tagcaagtga gtgtgctgat tcaaacacat ctctctcagc tgactcttta
     6241 aggtaaggtt ttctaccttt ataaactgtg aatgtgagta tgcccagcgg aatcccatgt
     6301 aatttcagta ctatttaaat aaactccatg ttttctttgg gcctaatatg ccttttgaag
     6361 tctgtataaa cttgttttca aatctaatct gttcatatga atataataaa aatacctttt
     6421 gcatggtaaa aattactttg attacaaaag atatatatat gctttttgtg accagcaata
     6481 agaaactgta atgactgata tttctattaa atgcacttaa ctatat
//
