LOCUS       NM_001106483            3232 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus grancalcin (Gca), mRNA.
ACCESSION   NM_001106483 XM_001055585 XM_229977
VERSION     NM_001106483.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3232)
  AUTHORS   Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M and
            Stoorvogel W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   2  (bases 1 to 3232)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 3232)
  AUTHORS   Hansen C, Tarabykina S, la Cour JM, Lollike K and Berchtold MW.
  TITLE     The PEF family proteins sorcin and grancalcin interact in vivo and
            in vitro
  JOURNAL   FEBS Lett 545 (2-3), 151-154 (2003)
   PUBMED   12804766
REFERENCE   4  (bases 1 to 3232)
  AUTHORS   Jia J, Borregaard N, Lollike K and Cygler M.
  TITLE     Structure of Ca(2+)-loaded human grancalcin
  JOURNAL   Acta Crystallogr D Biol Crystallogr 57 (Pt 12), 1843-1849 (2001)
   PUBMED   11717497
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000115.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001106483.5.
            
            On Mar 3, 2022 this sequence version replaced NM_001106483.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132264 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               JACYVU010000115.1  40754151-40754319
            170-343             JACYVU010000115.1  40764229-40764402
            344-413             JACYVU010000115.1  40773066-40773135
            414-457             JACYVU010000115.1  40778794-40778837
            458-605             JACYVU010000115.1  40779101-40779248
            606-719             JACYVU010000115.1  40782627-40782740
            720-778             JACYVU010000115.1  40783059-40783117
            779-3232            JACYVU010000115.1  40784281-40786734
FEATURES             Location/Qualifiers
     source          1..3232
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q21"
     gene            1..3232
                     /gene="Gca"
                     /note="grancalcin"
                     /db_xref="GeneID:295647"
                     /db_xref="RGD:1306589"
     exon            1..169
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     CDS             143..805
                     /gene="Gca"
                     /codon_start=1
                     /product="grancalcin"
                     /protein_id="NP_001099953.1"
                     /db_xref="GeneID:295647"
                     /db_xref="RGD:1306589"
                     /translation="MAYPGYGGAFGNFGGQIPGMQVQMGQPVPGAGPNMFSGGYPGYL
                     TYSDSYSPADDSMWTYFTAVAGQDGEVDAEELQRCLTQSGISGSYAPFSLETCRIMIA
                     MLDRDYTGKMGFNEFKELWAALNAWKQNFMSIDQDQSGTVEHHELSQAIALMGYRLSP
                     QTLAAIVRRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDFLQGTM
                     TI"
     exon            170..343
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            344..413
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            414..457
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            458..605
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            606..719
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            720..778
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
     exon            779..3232
                     /gene="Gca"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actctaggag gaggtggctc gcccagcggt ggtgcgcgat acagcgctcg gaccttccgc
       61 acctgtcgca cacacttgtg ccttcctcac agcagcgctg acgccgactt actggtgacg
      121 cgtgactttc gatctcctgg tcatggccta cccgggatac ggaggggcgt ttggaaactt
      181 cggcggtcag attccaggga tgcaagtgca aatgggccag cctgtgccag gcgcagggcc
      241 caatatgttc tctggtggtt accctgggta ccttacatac tctgacagct actcccctgc
      301 cgatgactcc atgtggactt acttcacggc tgttgctggg caggatggtg aggtggatgc
      361 tgaagagctg cagagatgct tgacacagtc tggaatcagt ggatcttatg ctcctttcag
      421 cttggaaacc tgcagaatta tgattgccat gttggataga gactacacag gaaaaatggg
      481 attcaacgag ttcaaggagc tttgggcagc tctcaatgcc tggaagcaga acttcatgag
      541 cattgaccag gatcaaagtg gcaccgtaga gcatcatgag ctgagtcaag ccatcgcgct
      601 catgggttac aggttgagtc cacagacatt agcagcgatt gttagacgct acagcaagaa
      661 tggccggatt ttctttgatg actatgtcgc ctgctgtgtg aagctccgtg ccctcacaga
      721 tttctttagg cgaagagacc acttgcaaca agggatcgtg aacttcatgt atgaagattt
      781 tttgcagggc accatgacaa tttgaaagcc tagcattcca aaggtggaga cagactgcga
      841 atccttctgc ttcattgaaa cagactggac tacctaaaat taaaagctcg cggaactttt
      901 ttgtatacct tcctgtgaaa gcaccccctt tcttttattt aaccttaaag cacagttcaa
      961 tgcaataact tttgtatttg ggatatatta tttttggaaa agttatgatg ttgcagatat
     1021 atgcacactc tcttggaatg aactaatggt gtgtagctaa ccgttaccag cgtacctgag
     1081 ccttagttct taacaattga gcatgtcaga atgtagtcat gtgacaggtt gtctttgaag
     1141 ccaaataaag aaagtctaga ttatctaaag gctacaagtt atagattttg ttggtacctg
     1201 tgggtgtttc tgggagtgag tcagagggga catctgcact ttgtgctgtc tttgggtttt
     1261 gataaacggt cagagaacat aacacatatt ctttcctgtg aatgagggat ctgtagctcc
     1321 taagactgtg tccttcctag attctgtcag cctagagcag taggcattgt ctcaccatct
     1381 ttgttgcatt gtttattgtc tacaatatgt tttatcatct tccactattg cctttgtttt
     1441 taaacttcaa ttttttttgt gttttgtgag acagggtctc tctgtgtaac ccagtggaac
     1501 agaaactcgt ggacctccta ccttgtgccc cattgtttgc agaaattcaa gacttgcaaa
     1561 cccttggcca tactaaagat ttcaactgaa gatgcctttc tctttcatta gtgaaggcat
     1621 agataacctg aaatgtcaac tgtctttgaa tcaaggagtt ttgaggactg ggtcatttta
     1681 gtgatgggtc agcattcatt cacctttttt tctgttacag cctggtgctg ctcctagtga
     1741 atggcaacag tttaaagaaa agcaagtaat ctgttactgt ttaactgttc agaaattcta
     1801 tgttgaattg gtagtgtgga cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     1861 tgtgtgtgta tcaaaaccca ccaagaaggg ttttgatatt tttctcttat atttttcccc
     1921 ctcctcctcc tcctccttct cttcctcccc ctcctcctcc tcctctccct tcctcctcct
     1981 cccccttcct cctcttctcc cttcctcctc ctctcccttc ctcctcctct cccttcctcc
     2041 tcctctccct cctgcccctc ctcctcccct tcttctacct cctcctcctg cttatggaaa
     2101 gcagcattcc tggtgaaatt ttctgtaaag atttcaagga gtgactaggt tctttgcatt
     2161 aagttgtctg ctctaagatg tcagagttag tttaatttct gaattttcat gtattttaac
     2221 taaatatact ctagctgaat tcagatgcaa atagataaaa ttttagttta gcttgtggca
     2281 aaattgaata tttgaaacag aacttcttga tttttaaaaa tattttttaa agaaaactcc
     2341 cccaaagtgc aacctctttt tataaataca gaaaacttaa caattagctt ttacttcaaa
     2401 agatcctgga aaggaaatga tgtctaatca ctctgacatt gattaatatg taacttgata
     2461 tcaaacccac tctgtcagtt ttctaaggat aggtcagtga gtaatccaca cacactgccc
     2521 tctgcctgct cgttcatgac catatactca gtagcctgaa gcagcattaa gagaaccact
     2581 gaatgcagaa tctgaagctg tgatagaaca cagaagccac atcatgatgt tgcaagtcac
     2641 tgagcaatgt acacccttaa tgtataagtg cttttatttg tacagtaaac atgtttccat
     2701 gtcgctttga gaatttttaa ataaacattc aaatagcttg ctgtaaagtt ttgtatcata
     2761 caaaatttgt tacgtatcta ctgtaatgag atgcttcagt tcaaacagcg gtgcattaat
     2821 tcaaccatta tctaaaagat tgccaaatgg gtaaatgtca cgtattgcac ttctagtctg
     2881 agtggcagtt tacacatttt aaattacatc aagggaaaat caatactatg ggaatcttga
     2941 tttggtccac tttaaatgta ttttaaggac tgtgctcatt aacctatttt aggcatgcat
     3001 tcagaaaagg aaagttaaca aatatatatt caagttatat atttatttcc agaaaaggcc
     3061 tttagcctgg aagaaagtag aatttatcaa ggtagtttaa actctgtgca attaaaaaaa
     3121 taacaaaaat caatttgtgg tatttcttta attaaaatat acaaatcatg ttcacttgta
     3181 accttatgat attactaatt gaacaaccaa aataaatact atttgtgaga aa
//
