LOCUS       NP_001093972             702 aa            linear   ROD 22-MAR-2023
DEFINITION  1,4-alpha-glucan-branching enzyme [Rattus norvegicus].
ACCESSION   NP_001093972 XP_001064453 XP_221747
VERSION     NP_001093972.1
DBSOURCE    REFSEQ: accession NM_001100502.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 702)
  AUTHORS   Radhakrishnan P, Moirangthem A, Nayak SS, Shukla A, Mathew M and
            Girisha KM.
  TITLE     Novel pathogenic variants in GBE1 causing fetal akinesia
            deformation sequence and severe neuromuscular form of glycogen
            storage disease type IV
  JOURNAL   Clin Dysmorphol 28 (1), 17-21 (2019)
   PUBMED   30303820
REFERENCE   2  (residues 1 to 702)
  AUTHORS   Hong EP, Go MJ, Kim HL and Park JW.
  TITLE     Risk prediction of pulmonary tuberculosis using genetic and
            conventional risk factors in adult Korean population
  JOURNAL   PLoS One 12 (3), e0174642 (2017)
   PUBMED   28355295
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 702)
  AUTHORS   Froese DS, Michaeli A, McCorvie TJ, Krojer T, Sasi M, Melaev E,
            Goldblum A, Zatsepin M, Lossos A, Alvarez R, Escriba PV, Minassian
            BA, von Delft F, Kakhlon O and Yue WW.
  TITLE     Structural basis of glycogen branching enzyme deficiency and
            pharmacologic rescue by rational peptide design
  JOURNAL   Hum Mol Genet 24 (20), 5667-5676 (2015)
   PUBMED   26199317
REFERENCE   4  (residues 1 to 702)
  AUTHORS   Kakhlon O, Glickstein H, Feinstein N, Liu Y, Baba O, Terashima T,
            Akman HO, Dimauro S and Lossos A.
  TITLE     Polyglucosan neurotoxicity caused by glycogen branching enzyme
            deficiency can be reversed by inhibition of glycogen synthase
  JOURNAL   J Neurochem 127 (1), 101-113 (2013)
   PUBMED   23607684
REFERENCE   5  (residues 1 to 702)
  AUTHORS   Murphy RM, Xu H, Latchman H, Larkins NT, Gooley PR and Stapleton
            DI.
  TITLE     Single fiber analyses of glycogen-related proteins reveal their
            differential association with glycogen in rat skeletal muscle
  JOURNAL   Am J Physiol Cell Physiol 303 (11), C1146-C1155 (2012)
   PUBMED   23015546
REFERENCE   6  (residues 1 to 702)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (residues 1 to 702)
  AUTHORS   Hong SJ, Li H, Becker KG, Dawson VL and Dawson TM.
  TITLE     Identification and analysis of plasticity-induced late-response
            genes
  JOURNAL   Proc Natl Acad Sci U S A 101 (7), 2145-2150 (2004)
   PUBMED   14766980
REFERENCE   8  (residues 1 to 702)
  AUTHORS   Bao Y, Kishnani P, Wu JY and Chen YT.
  TITLE     Hepatic and neuromuscular forms of glycogen storage disease type IV
            caused by mutations in the same glycogen-branching enzyme gene
  JOURNAL   J Clin Invest 97 (4), 941-948 (1996)
   PUBMED   8613547
REFERENCE   9  (residues 1 to 702)
  AUTHORS   Satoh,K. and Sato,K.
  TITLE     Glycogen-binding protein components of rat tissues
  JOURNAL   Biochem Biophys Res Commun 96 (1), 28-33 (1980)
   PUBMED   6449198
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB724963.1, CB546687.1, BC090037.1 and BI284270.1.
            
            On or before Dec 18, 2009 this sequence version replaced
            XP_221747.4, XP_001064453.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11p11"
     Protein         1..702
                     /product="1,4-alpha-glucan-branching enzyme"
                     /EC_number="2.4.1.18"
                     /note="glucan (1,4-alpha-), branching enzyme 1"
                     /calculated_mol_wt=80288
     Region          15..699
                     /region_name="PLN02447"
                     /note="1,4-alpha-glucan-branching enzyme"
                     /db_xref="CDD:215246"
     CDS             1..702
                     /gene="Gbe1"
                     /coded_by="NM_001100502.1:128..2236"
                     /db_xref="GeneID:288333"
                     /db_xref="RGD:1309968"
ORIGIN      
        1 maapaapaae ekgseaqlka aladvpelgr lleidpylkp yaadfqrryk kfnqvlhdig
       61 eneggidkfs rgyesfgihr csdggiycke wapgaegvfl tgefsgwnpf shpykkleyg
      121 kwelyippkq nksppiphgs klkvvitsks geilyrispw akyvvrennn vnydwihwdp
      181 enpykfrhsr pkkprslriy eshvgisshe gkiasykhft snvlprikdl gynciqlmai
      241 mehayyasfg yqvtsffaas srygtpeelk elvdtahlmg ivvlldvvhs hasknsedgl
      301 nmfdgtdscy fhsgprgthd lwdsrlfiys swevlrflls nirwwleeyc fdgfrfdgvt
      361 smlyhhhgmg qgfsgdysey fglqvdedal vylmlanhlt htmypdsiti aedvsgmpal
      421 csptsqgggg fdyrlamaip dkwiqllkef kdedwnmgni vytltnrrhl ekcvayaesh
      481 dqalvgdktl afwlmdaemy tnmsvlapft pvidrgiqlh kmirlithgl ggegylnfmg
      541 nefghpewld fprkgnnesy hyarrqfnlt dddllrykfl nnfdrdmnrl eetcgwlsap
      601 qayvsekheg nktitferag llfifnfhps ksytdyrvgt ampgkfkivl dsdaaeyggh
      661 qrldhstdyf aeafehngrp ysllvyipsr valilqnvdl pn
//
