LOCUS       NM_001399231            2767 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus glutamyl-tRNA amidotransferase subunit B (Gatb),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001399231 XM_003749312
VERSION     NM_001399231.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2767)
  AUTHORS   Echevarria,L., Clemente,P., Hernandez-Sierra,R., Gallardo,M.E.,
            Fernandez-Moreno,M.A. and Garesse,R.
  TITLE     Glutamyl-tRNAGln amidotransferase is essential for mammalian
            mitochondrial translation in vivo
  JOURNAL   Biochem J 460 (1), 91-101 (2014)
   PUBMED   24579914
REFERENCE   2  (bases 1 to 2767)
  AUTHORS   Nagao,A., Suzuki,T., Katoh,T., Sakaguchi,Y. and Suzuki,T.
  TITLE     Biogenesis of glutaminyl-mt tRNAGln in human mitochondria
  JOURNAL   Proc Natl Acad Sci U S A 106 (38), 16209-16214 (2009)
   PUBMED   19805282
REFERENCE   3  (bases 1 to 2767)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jan 5, 2022 this sequence version replaced XM_003749312.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.9248.1,
                                           SRR26643292.9202.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               JAXUCZ010000002.1  173228568-173228768
            202-352             JAXUCZ010000002.1  173230283-173230433
            353-466             JAXUCZ010000002.1  173256301-173256414
            467-665             JAXUCZ010000002.1  173258770-173258968
            666-788             JAXUCZ010000002.1  173259392-173259514
            789-902             JAXUCZ010000002.1  173265587-173265700
            903-987             JAXUCZ010000002.1  173267672-173267756
            988-1032            JAXUCZ010000002.1  173269423-173269467
            1033-1222           JAXUCZ010000002.1  173271131-173271320
            1223-1356           JAXUCZ010000002.1  173295281-173295414
            1357-1435           JAXUCZ010000002.1  173305625-173305703
            1436-1570           JAXUCZ010000002.1  173312527-173312661
            1571-2767           JAXUCZ010000002.1  173313948-173315144
FEATURES             Location/Qualifiers
     source          1..2767
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2767
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /note="glutamyl-tRNA amidotransferase subunit B"
                     /db_xref="GeneID:361974"
                     /db_xref="RGD:1307864"
     exon            1..201
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1699
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /note="glutamyl-tRNA(Gln) amidotransferase, subunit B;
                     PET112-like"
                     /codon_start=1
                     /product="glutamyl-tRNA(Gln) amidotransferase subunit B,
                     mitochondrial"
                     /protein_id="NP_001386160.1"
                     /db_xref="GeneID:361974"
                     /db_xref="RGD:1307864"
                     /translation="MAAPVLRSGFPGRRWALAWIDDCSRLRSGSQIGPISNWARRQSS
                     VAQPSLHTAQKPRKGEHKWAAVVGLEIHAQISSNSKLFSGAQVCFAAPPNSLVSYFDA
                     SLPGTLPVLNRRCVEAAVMAGLALNCHINKKSLFDRKHYFYSDLPAGYQITQQRLPIA
                     TNGHLTYSIYLGKKHSQVTTKTVRIKQIQLEQDSGKSLHDDLRSQTLIDLNRAGIGLL
                     EVVLEPDLCCGEEAALAVRELQLILQALGASQANMAEGQLRVDANISVHHPGEALGVR
                     TEVKNLNSLRFLAKAIDYEIQRQITELENGGEILNETRSFDYKRGCTMPMRDKEGKQD
                     YRFMPEPNLPPLVLYDDTSVPPDADPQQVISIDRLRDMLPELPSATRERLVQQYGMLP
                     EHSFALLNEVGLLEFFQNVIKETRAEPKKVTNWVLNTFLCYLKHQNLAVSESPVTPSA
                     LAELLDLLDSKAISSSAAKQVFEELWRGEGKTAAQIVSEQQLELIQDEEALEELCQAT
                     IEGHPQVVMDVKKRNPKAINKLVGLVRKASLSRADPALIKEILEKKLSL"
     exon            202..352
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            353..466
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            467..665
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            666..788
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            789..902
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            903..987
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1032
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1222
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1356
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1435
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1436..1570
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..2767
                     /gene="Gatb"
                     /gene_synonym="Pet112l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acctgacccg gtcttcggca atgcaatggc ggcacccgtg ctgcgttcgg gtttccctgg
       61 aagacgctgg gctttagcgt ggatagacga ctgttcccgc ctccgaagtg gctctcaaat
      121 tgggcccata tccaactggg ctaggagaca gagttcagtg gctcagcctt ccctccacac
      181 ggctcagaag ccgaggaaag gtgaacacaa atgggcagct gtagtaggat tggaaattca
      241 tgcgcagatt tcctccaact ctaaactctt ctctggagct caagtatgct ttgcagcacc
      301 tccgaattct ttggtttctt attttgatgc atctctgcct ggaactttac cggttctcaa
      361 caggaggtgt gtggaagccg cagtgatggc tggcttagca ctgaactgcc acataaacaa
      421 gaagtccttg tttgacagga agcactactt ctactcagac cttccggccg gctaccagat
      481 cacccagcag aggctcccga ttgctaccaa tggacacttg acctacagta tctatctagg
      541 gaagaaacac agtcaggtga ccaccaagac agtgaggatc aagcagatcc aactggagca
      601 ggacagtggc aaaagcctcc atgatgacct gaggtcgcag acactcattg atttgaacag
      661 agctggaatt ggccttcttg aagtggtcct ggagcctgac ctctgctgtg gagaagaggc
      721 agccctcgct gtcagggaac tgcagctgat ccttcaagcc ctgggcgcca gccaagccaa
      781 catggcagag ggtcagctga gagtggatgc caatatatcg gtacatcatc ctggagaagc
      841 cctgggcgtc cggactgaag taaagaatct caacagcctc agattcttgg ccaaagccat
      901 agactatgaa attcagaggc aaatcaccga acttgaaaat ggaggtgaaa ttctgaatga
      961 aacccgttca tttgattata agcgggggtg caccatgcca atgagagaca aagaagggaa
     1021 acaagactac aggtttatgc cggagcctaa cctgcccccc ttagtgctct acgatgacac
     1081 atctgtgcca ccagatgcag accctcagca ggtgatcagt attgaccggc tgagggacat
     1141 gctcccagag ctccccagtg caaccagaga aaggcttgtc cagcaatatg ggatgctgcc
     1201 ggagcacagc tttgccttac tgaatgaagt tggcctactg gagttcttcc agaatgtgat
     1261 aaaagaaact agggcagagc caaaaaaggt gactaactgg gtcctgaaca cttttctgtg
     1321 ctatttaaag caccagaatc tcgcagtcag tgagagtcct gtcacaccct ctgcacttgc
     1381 cgagctcctc gacctgctgg acagtaaagc aatttcttcc tcagcagcta agcaggtgtt
     1441 tgaggagctg tggaggggag aggggaagac agcagcacag atcgtgtcag agcagcagct
     1501 ggagctcata caggatgagg aggccctgga agaactctgc caggctacca tagagggaca
     1561 cccccaagtg gtgatggatg tgaagaaaag gaaccccaaa gccataaata agttggttgg
     1621 gttggtccgg aaagcaagcc taagccgagc agacccggct ctgataaagg agatactgga
     1681 gaagaagctg tcactgtgag gcctgtgagg gctgccgtcc acgtgctgta cagattgtat
     1741 ctcttagtcc ctagccaagc tccatctcct aggagactag gagataacaa cactttacac
     1801 atgcgtgtgt cctctcagac cccacgacct gagaggcagc cgtcatggaa gaccagcagc
     1861 cagagcatca gcctcactct ctggaaatgg tccatgatgg tggcagcagt gactaaagaa
     1921 atcgtcattc taaaactcag atgccatggg ttcttcctag agcccagcgg tggtccccag
     1981 ctgtactggc tgggtttgtg tgtcaacttg acacaagctg gaatcatcac agagaaagga
     2041 gcctcccgtg aggaaatgcc tccatgagat ccagctgtaa gtcattttct caatcagtga
     2101 tcaaggggga agggcccagc cccttgtgag cggtgccgtc cctgggctgg tggtcctggg
     2161 ctctataaga gagcaagctg agcaagccag gggaagcaag ccagtaagta acatcccttc
     2221 atggcctctg catcagctcc tgcttcctaa cctgcttgag ttccagtcct gacttccttt
     2281 ggtgatgaac agcaatgtgg aagtgtaagc tgaataaacc ctttctcccc aacttgcttc
     2341 ttggtcctga tgtgtgtgca ggaataggaa ccctcaccaa gatccatcct aaagggaaac
     2401 cgtgactaag acccatccga agggccaacg gacgagagcc atggcagcat gggcatggca
     2461 aagaagaaac aaaggaaatg ggcaaggagg gggcaggagg gtgctggcgc tcacctgcac
     2521 gtgtaggcac tactgcctgc tcagctccca gtgcatcaag gtgacactca agttctcaca
     2581 taaatttaat gaataaaata tataccaaaa tagcacataa aaattaactt ccacttaaga
     2641 gattgtatag tttacacccc tcccacacac aatgcctaga ccaaaaaaaa agaaaaattg
     2701 aagcattaag ttgtttacct gggaagaata agattatagt ctaataaatc agaatgctga
     2761 cctttaa
//
