LOCUS       NM_001399652            2481 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus GATA zinc finger domain containing 1 (Gatad1),
            mRNA.
ACCESSION   NM_001399652 XM_575359
VERSION     NM_001399652.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Lomniczi,A., Wright,H., Castellano,J.M., Matagne,V., Toro,C.A.,
            Ramaswamy,S., Plant,T.M. and Ojeda,S.R.
  TITLE     Epigenetic regulation of puberty via Zinc finger protein-mediated
            transcriptional repression
  JOURNAL   Nat Commun 6, 10195 (2015)
   PUBMED   26671628
  REMARK    GeneRIF: GATAD1 delivery to hypothalamus delays puberty by
            impairing the transition of a transcriptional network from an
            immature repressive epigenetic configuration to one of activation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  AUTHORS   Theis,J.L., Sharpe,K.M., Matsumoto,M.E., Chai,H.S., Nair,A.A.,
            Theis,J.D., de Andrade,M., Wieben,E.D., Michels,V.V. and Olson,T.M.
  TITLE     Homozygosity mapping and exome sequencing reveal GATAD1 mutation in
            autosomal recessive dilated cardiomyopathy
  JOURNAL   Circ Cardiovasc Genet 4 (6), 585-594 (2011)
   PUBMED   21965549
REFERENCE   3  (bases 1 to 2481)
  AUTHORS   Vermeulen,M., Eberl,H.C., Matarese,F., Marks,H., Denissov,S.,
            Butter,F., Lee,K.K., Olsen,J.V., Hyman,A.A., Stunnenberg,H.G. and
            Mann,M.
  TITLE     Quantitative interaction proteomics and genome-wide profiling of
            epigenetic histone marks and their readers
  JOURNAL   Cell 142 (6), 967-980 (2010)
   PUBMED   20850016
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 12, 2022 this sequence version replaced XM_575359.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.2756304.1,
                                           SRR21887620.1185952.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-554               JAXUCZ010000004.1  31462309-31462862
            555-680             JAXUCZ010000004.1  31463356-31463481
            681-740             JAXUCZ010000004.1  31465368-31465427
            741-924             JAXUCZ010000004.1  31470009-31470192
            925-2481            JAXUCZ010000004.1  31472271-31473827
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q13"
     gene            1..2481
                     /gene="Gatad1"
                     /note="GATA zinc finger domain containing 1"
                     /db_xref="GeneID:500005"
                     /db_xref="RGD:1562004"
     exon            1..554
                     /gene="Gatad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             321..1115
                     /gene="Gatad1"
                     /codon_start=1
                     /product="GATA zinc finger domain-containing protein 1"
                     /protein_id="NP_001386581.1"
                     /db_xref="GeneID:500005"
                     /db_xref="RGD:1562004"
                     /translation="MPLGLKPTCSMCKTTSSSMWKKSPQGEILCHHCTGRGGGGGGAG
                     VAGGTGGGGGFGTATFATTSAGPSQSNGGGGGKQSKQEIHRRSARLRNTKYKSAPAAE
                     KKVSTKGKGRRHIFKLKNPIKAPESVSTIVTAESIFYKGVYYQIGDVVSVIDEQDGKP
                     YYAQIRGFIQDQYCEKSAALTWLIPTLASPRDQFDPASYIIGPEEDLPRKMEYLEFVC
                     HAPSEYFKSRSSPFPTVPTRPEKGYIWTHVGPTPAITMKETVANHL"
     exon            555..680
                     /gene="Gatad1"
                     /inference="alignment:Splign:2.1.0"
     exon            681..740
                     /gene="Gatad1"
                     /inference="alignment:Splign:2.1.0"
     exon            741..924
                     /gene="Gatad1"
                     /inference="alignment:Splign:2.1.0"
     exon            925..2481
                     /gene="Gatad1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctcgggacc cgggcggccc ggtccgcccc gggtagcgtc ccccgggtcc cccgagctgg
       61 ctttcccagg aggccgggac gagtttcggg cctccgtgcc ccgcgggcgg cccagctcca
      121 gagctggggc ccgggctgct ggggcccgct tcccgcctcc aggggccggc ggcggccgct
      181 gggtaccggc gcgggcggct cagcacctca gaccttgctc ttccagtcgc cgaggtggcg
      241 ggccgacccc tgggcggcca gtgcagacgg ccgccattcc cgtgtcgctg cgaccgcggg
      301 ggccgcccga gccgcccacc atgccgctgg gcctgaagcc cacctgcagc atgtgcaaga
      361 ccacgtcgtc ctccatgtgg aagaagagtc cacagggcga gatcctctgt catcactgca
      421 ccggccgggg cggcgggggc ggcggcgcgg gagtggcggg cgggaccggg ggcggaggcg
      481 gcttcggcac tgctaccttc gccaccacct cggccggtcc gtcgcagagc aacgggggcg
      541 ggggcggcaa gcagagtaag caagaaattc acagaaggtc tgctcggctc agaaatacca
      601 agtacaaatc tgctccagct gctgaaaaga aagtttccac taaaggaaaa gggagaagac
      661 atatttttaa gttaaaaaac cctatcaaag ctcctgagtc tgtttctacc atagtcactg
      721 cagagtcaat cttctacaag ggagtatatt accaaattgg tgatgttgtt tctgtgattg
      781 atgagcaaga tgggaagccg tactatgctc agatcagggg tttcattcag gaccagtatt
      841 gtgagaagag tgccgcactg acatggctca ttcccaccct cgctagtccc agagaccagt
      901 ttgatcctgc atcatatata atagggccag aggaagacct tccaaggaag atggagtacc
      961 tggaatttgt ctgccacgcc ccttctgagt atttcaagtc aaggtcatca ccatttccca
     1021 cagttcccac ccgaccagag aagggctaca tatggactca tgtcggacct actcctgcaa
     1081 taactatgaa ggaaacagtt gccaaccact tgtagttaca aaaccaaacc ggggcatgct
     1141 tacttagcta gtgtaaagct tcagttttaa tcctagaaca tacatacaga tcccaaaata
     1201 aagccggatt ttcagttttc ttatatttat aacaagatat gccacacatt ttctctttaa
     1261 aacttttttc tttaagtttt tgagataggg tctcatatgt cgcccaggct agcttgacct
     1321 tgagatcccc ctgcctcatc ctccttgagt gctggaatta caggtgtgtt agaccatagc
     1381 tggttaaagc cagctacttc ttcatgaagt tcttacatgg aaatatgact ggagaaaaat
     1441 tttaactacc cagtaagtat attaccttgc ttagtatctg ttgctttgaa aaccacaaag
     1501 tgaaaaaaga atgaattgcc gtcaaatact gtttaatgaa tattttccta ggcaaagtga
     1561 cagattccag agaaatcatt ataaacatgc agtgtctatt tttcttcata atttatttct
     1621 aggaactcat aaagtgaatt atatttttac aggtataaaa acattaagtt ttagactttt
     1681 tctgtctttt attttttttt aacccaggat ctcactatgc agccctggct gccctggaac
     1741 tcactctgta gaccagactg acattgatct taagagatct acctgcctct gcctcccaag
     1801 tgctgggact aaaggtgtgc accaccatgg caggtttaag ttttagattt ctgatcaagg
     1861 actaaaccaa aatgtgacca gtatgtctta caaagccaca cagacttttt ccttctttag
     1921 aagcagacct tgtctgcttt agtcctacag aaagcaacta gtgggtgatt gattagccct
     1981 ggctctgtat actttcatct cacgccatac cattcaactg ctttcagtag acatgccttt
     2041 gcctgtcatc agctacttct gtgggacttc agccaggcct ttggtctaca cacagtatag
     2101 atatccctcc tcctactgag gcagcagcag cagcctctgt gagggtagcc tgactatggc
     2161 taagacaggg actggtgact ggctatcttg aaagtgacta aaaggtcatt agttttggta
     2221 tgatggaggg aagtgggcgg gtacctgcct ctgtcctgat ctatccagac agacgttttt
     2281 agctgtagga atttataagg atttgacttg atcttgatga ttttcatcag aatgctttca
     2341 cctttttctt tgtcccaaag ttgggaagaa gcatcttcat gtttacataa ggtatcaaat
     2401 acagttcatt gtttatacta ttagaaatga ttttctaaat attaatattc cagtttctca
     2461 ttaaaaaaca tttttacagt g
//
