LOCUS       NM_001024316            2110 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus GATA binding protein 5 (Gata5), mRNA.
ACCESSION   NM_001024316 XM_575299
VERSION     NM_001024316.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Song Z, Chen L, Pang S and Yan B.
  TITLE     Molecular genetic study on GATA5 gene promoter in acute myocardial
            infarction
  JOURNAL   PLoS One 16 (3), e0248203 (2021)
   PUBMED   33684162
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2110)
  AUTHORS   Wu GJ, Wang W, Lin YL, Liu SH and Chen RM.
  TITLE     Oxidative stress-induced apoptotic insults to rat osteoblasts are
            attenuated by nitric oxide pretreatment via GATA-5-involved
            regulation of Bcl-X L gene expression and protein translocation
  JOURNAL   Arch Toxicol 90 (4), 905-916 (2016)
   PUBMED   25726415
REFERENCE   3  (bases 1 to 2110)
  AUTHORS   Messaoudi S, He Y, Gutsol A, Wight A, Hebert RL, Vilmundarson RO,
            Makrigiannis AP, Chalmers J, Hamet P, Tremblay J, McPherson R,
            Stewart AFR, Touyz RM and Nemer M.
  TITLE     Endothelial Gata5 transcription factor regulates blood pressure
  JOURNAL   Nat Commun 6, 8835 (2015)
   PUBMED   26617239
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2110)
  AUTHORS   Zhang XL, Dai N, Tang K, Chen YQ, Chen W, Wang J, Zhao CM, Yuan F,
            Qiu XB, Qu XK, Yang YQ and Xu YW.
  TITLE     GATA5 loss-of-function mutation in familial dilated cardiomyopathy
  JOURNAL   Int J Mol Med 35 (3), 763-770 (2015)
   PUBMED   25543888
REFERENCE   5  (bases 1 to 2110)
  AUTHORS   Shi LM, Tao JW, Qiu XB, Wang J, Yuan F, Xu L, Liu H, Li RG, Xu YJ,
            Wang Q, Zheng HZ, Li X, Wang XZ, Zhang M, Qu XK and Yang YQ.
  TITLE     GATA5 loss-of-function mutations associated with congenital
            bicuspid aortic valve
  JOURNAL   Int J Mol Med 33 (5), 1219-1226 (2014)
   PUBMED   24638895
REFERENCE   6  (bases 1 to 2110)
  AUTHORS   Rojas A, De Val S, Heidt AB, Xu SM, Bristow J and Black BL.
  TITLE     Gata4 expression in lateral mesoderm is downstream of BMP4 and is
            activated directly by Forkhead and GATA transcription factors
            through a distal enhancer element
  JOURNAL   Development 132 (15), 3405-3417 (2005)
   PUBMED   15987774
REFERENCE   7  (bases 1 to 2110)
  AUTHORS   Ren CY, Akiyama Y, Miyake S and Yuasa Y.
  TITLE     Transcription factor GATA-5 selectively up-regulates mucin gene
            expression
  JOURNAL   J Cancer Res Clin Oncol 130 (5), 245-252 (2004)
   PUBMED   14986113
REFERENCE   8  (bases 1 to 2110)
  AUTHORS   Di Lisi R, Millino C, Calabria E, Altruda F, Schiaffino S and
            Ausoni S.
  TITLE     Combinatorial cis-acting elements control tissue-specific
            activation of the cardiac troponin I gene in vitro and in vivo
  JOURNAL   J Biol Chem 273 (39), 25371-25380 (1998)
   PUBMED   9738004
REFERENCE   9  (bases 1 to 2110)
  AUTHORS   Gao X, Sedgwick T, Shi YB and Evans T.
  TITLE     Distinct functions are implicated for the GATA-4, -5, and -6
            transcription factors in the regulation of intestine epithelial
            cell differentiation
  JOURNAL   Mol Cell Biol 18 (5), 2901-2911 (1998)
   PUBMED   9566909
REFERENCE   10 (bases 1 to 2110)
  AUTHORS   Morrisey EE, Ip HS, Tang Z, Lu MM and Parmacek MS.
  TITLE     GATA-5: a transcriptional activator expressed in a novel temporally
            and spatially-restricted pattern during embryonic development
  JOURNAL   Dev Biol 183 (1), 21-36 (1997)
   PUBMED   9119112
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085855.1.
            
            On May 27, 2005 this sequence version replaced XM_575299.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085855.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN11044071, SAMN16676784
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..2110
                     /gene="Gata5"
                     /note="GATA binding protein 5"
                     /db_xref="GeneID:499951"
                     /db_xref="RGD:1561365"
     exon            1..842
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..1513
                     /gene="Gata5"
                     /codon_start=1
                     /product="transcription factor GATA-5"
                     /protein_id="NP_001019487.1"
                     /db_xref="GeneID:499951"
                     /db_xref="RGD:1561365"
                     /translation="MYQSLALAQSPGQGTYADSGPFLHSSGAGSPVFVAPTRVPSMLP
                     YLPSCEPGSQPPALAAHSSWTQAVSAESSAFGSGSPHPPATHPPGATAFPFAHSPSGS
                     GSGGSAGVRDGAAFQSALLAREQYPTALGRPMSASYPTTYPAYVSPDVAPSWTSGPFD
                     SSILHGLQGRPGGLPGRRTTFVPDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCN
                     ACGLYHKMNGVNRPLVRPQKRLSSSRRSGLCCSNCHTATTTLWRRNAEGEPVCNACGL
                     YMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANSTASSPTLLNTESSATTL
                     KAESSLASPGCAGPTITSQASSPADESLASSHLEFKFEPEDFVFTSSSLSPQAGLSGV
                     LRQEAWCALALA"
     exon            843..1018
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1144
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1232
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1357
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..2087
                     /gene="Gata5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctacaaccca ctggtcaccc gccctgggcc agcgccgcgc tttcctgtga gggttttggc
       61 cggtgatctc tgctcgaagc aaggaccgtg ttcctggggt cctgcgcctc atctaacctc
      121 tcgttccacc cggagaaccc cgggacctgt gccggtgaac cgactcagaa aagtggagtg
      181 tgcaagccga gcagcagcac ctgcccacgg cgagcgcaat agctgatgga gggggcccag
      241 tgatcctgcc ctagacgcct gtctttcttc tctgcaggtc aagctcgctc agggaaaaat
      301 gtaccagagc ttggcgctgg cccagagccc cggccagggt acctacgccg attctggacc
      361 ctttctgcat tcttcgggag ccggttcccc ggtgttcgtg gcacccactc gcgtgccctc
      421 catgctgccg tacctgcctt cgtgtgagcc gggctcgcag cctcccgcgc tcgccgcgca
      481 ctctagctgg acgcaagcgg tttccgctga atcctcagcc ttcggctccg gaagcccgca
      541 cccgccagcc acacacccac cgggagccac cgccttcccg ttcgctcaca gcccctcggg
      601 gtcgggcagc ggcggcagcg cgggagtccg ggacggcgcc gccttccaga gcgccctgct
      661 ggctcgcgaa cagtatccga ctgcgctcgg gaggcccatg agcgcctcgt accccacaac
      721 ctacccagca tacgtgagtc ccgacgtagc cccttcgtgg acctctggac ccttcgacag
      781 cagcatcctg cacggtctgc aaggtcgccc tggtggcctc cctggccgca ggaccacctt
      841 cgtacctgac ttcttggagg agttccctgg tgagggccgg gagtgtgtca actgtggagc
      901 cctgtctaca ccactgtggc gcagggatgg caccggacac tatctatgca acgcctgtgg
      961 cctctatcac aagatgaatg gggtcaaccg accgctagtg aggccccaga agcgtctgtc
     1021 ctcatcccgt cgatctggcc tctgctgttc caactgccac actgctacca ccaccctctg
     1081 gaggcgcaac gcagaggggg aaccagtgtg caacgcctgt ggcctctaca tgaagctcca
     1141 tggggtgcca aggccactgg cgatgaaaaa ggagagtatc cagacaagaa aacggaagcc
     1201 gaagaaccct gccaaaatca agggctcctc gggatccaca gccaacagca cagcctcttc
     1261 tcccactctc ctcaacaccg agagctcagc caccactttg aaggcagagt ccagtctggc
     1321 atctccaggg tgtgctggac ccactatcac ctcccaggcc tccagcccag cggacgaatc
     1381 cctggcctcc agccatttgg agttcaagtt cgaacctgaa gactttgtct tcacctcctc
     1441 gtccctgagc ccccaggctg gtctcagtgg ggtcctacgt caggaggcct ggtgtgccct
     1501 ggccttggcc taggtgctca ggaaactgtt accacagtgt atctcaggaa cagaagttag
     1561 ttcctgaacc agcagcccca gaggtccctc accactgtgc tggggaaact tttctgtgcc
     1621 aattgcctag agaaaaaagc aggctggtgg acgaagggtt ggagcctcgg ctagggtagt
     1681 aatggactcc ccaggcccct cgtggacctc tctgcagcca agatgactgg agatacccac
     1741 caattacttg aattcagctc ttgacatcga tggtcaaaat ttaaagtttg tagcagctgg
     1801 caacggttca cagcatccca cagtaaaatc cgatccaagt gaaacaaaca tagtccgggc
     1861 aggcaataag aaacagggcc tctgggccct cgaggtcttc atttctcatg tttgactgtg
     1921 cacagcttgc ttatggacgc aggactgcca gagaccagtg tacaggttga gcactgtacc
     1981 agggcactgc cccaaggcaa acgcattcct ccagccgtct tcacagactt ctgtatttat
     2041 ttgtatgttg gtttggggcc aggtagtaaa gggccttttt ctgtcaaaaa aaaaaaaaaa
     2101 aaaaaaaaaa
//
