LOCUS       NM_001024306            1386 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus GAR1 ribonucleoprotein (Gar1), mRNA.
ACCESSION   NM_001024306 XM_575037
VERSION     NM_001024306.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1386)
  AUTHORS   Nguyen,T.H.D., Tam,J., Wu,R.A., Greber,B.J., Toso,D., Nogales,E.
            and Collins,K.
  TITLE     Cryo-EM structure of substrate-bound human telomerase holoenzyme
  JOURNAL   Nature 557 (7704), 190-195 (2018)
   PUBMED   29695869
REFERENCE   2  (bases 1 to 1386)
  AUTHORS   Grolimund,L., Aeby,E., Hamelin,R., Armand,F., Chiappe,D.,
            Moniatte,M. and Lingner,J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   3  (bases 1 to 1386)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1386)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1386)
  AUTHORS   Watkins,N.J. and Bohnsack,M.T.
  TITLE     The box C/D and H/ACA snoRNPs: key players in the modification,
            processing and the dynamic folding of ribosomal RNA
  JOURNAL   Wiley Interdiscip Rev RNA 3 (3), 397-414 (2012)
   PUBMED   22065625
  REMARK    Review article
REFERENCE   6  (bases 1 to 1386)
  AUTHORS   Egan,E.D. and Collins,K.
  TITLE     Specificity and stoichiometry of subunit interactions in the human
            telomerase holoenzyme assembled in vivo
  JOURNAL   Mol Cell Biol 30 (11), 2775-2786 (2010)
   PUBMED   20351177
REFERENCE   7  (bases 1 to 1386)
  AUTHORS   Dejardin,J. and Kingston,R.E.
  TITLE     Purification of proteins associated with specific genomic Loci
  JOURNAL   Cell 136 (1), 175-186 (2009)
   PUBMED   19135898
REFERENCE   8  (bases 1 to 1386)
  AUTHORS   Fu,D. and Collins,K.
  TITLE     Purification of human telomerase complexes identifies factors
            involved in telomerase biogenesis and telomere length regulation
  JOURNAL   Mol Cell 28 (5), 773-785 (2007)
   PUBMED   18082603
REFERENCE   9  (bases 1 to 1386)
  AUTHORS   Wang,C., Query,C.C. and Meier,U.T.
  TITLE     Immunopurified small nucleolar ribonucleoprotein particles
            pseudouridylate rRNA independently of their association with
            phosphorylated Nopp140
  JOURNAL   Mol Cell Biol 22 (24), 8457-8466 (2002)
   PUBMED   12446766
REFERENCE   10 (bases 1 to 1386)
  AUTHORS   Dragon,F., Pogacic,V. and Filipowicz,W.
  TITLE     In vitro assembly of human H/ACA small nucleolar RNPs reveals
            unique features of U17 and telomerase RNAs
  JOURNAL   Mol Cell Biol 20 (9), 3037-3048 (2000)
   PUBMED   10757788
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079131.1.
            
            On May 27, 2005 this sequence version replaced XM_575037.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079131.1, SRR8487231.23953.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676808 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1386
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q43"
     gene            1..1386
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /note="GAR1 ribonucleoprotein"
                     /db_xref="GeneID:499709"
                     /db_xref="RGD:1563995"
     exon            1..257
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     exon            258..489
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..950
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /note="snoRNP protein GAR1; nucleolar protein family A
                     member 1; GAR1 homolog, ribonucleoprotein; nucleolar
                     protein family A, member 1 (H/ACA small nucleolar RNPs);
                     GAR1 ribonucleoprotein homolog"
                     /codon_start=1
                     /product="H/ACA ribonucleoprotein complex subunit 1"
                     /protein_id="NP_001019477.1"
                     /db_xref="GeneID:499709"
                     /db_xref="RGD:1563995"
                     /translation="MSFRGGGRGGFNRGGGGGGFNRGGGSNNHFRGGGGGGGGGGNFR
                     GGGRGGFGRGGGRGGFNKFQDQGPPERVVLLGEFMHPCEDDIVCKCTTEENKVPYFNA
                     PVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFL
                     PRPPGEKGPPRGGGGGGGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGFRGGRGGG
                     GGFRGRGH"
     exon            490..644
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     exon            645..704
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     exon            705..864
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     exon            865..936
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
     exon            937..1352
                     /gene="Gar1"
                     /gene_synonym="Nola1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccctagcga ggtggacctt gcgcgggtga ggtgggggtc acgctgggtg ctattgtttc
       61 tcttccggtg ctgtatgctc tcttcgggaa ggcattagga ccgttgcgtc taagtagtga
      121 cagcctcttc ctgcaaacca gcccttccaa tatctagtct ggtaaaattg taccgtacgg
      181 tggccgagga ggtttaagcg cgccggaagt atcgctccgc gcgcgcgccc agctgagcta
      241 gagacgcacg tggcgcggcc ggagagagca tgtctttccg aggcggaggt cgcggaggct
      301 ttaatcgcgg tggtggaggt ggaggcttca atcgtggcgg cggcagcaac aaccacttcc
      361 gagggggcgg cggcggtggt ggcggcggcg gcaatttcag gggcggcggc cgaggaggat
      421 ttggacgagg gggcggtcgt ggaggcttca ataaattcca agatcaaggg cctccagaac
      481 gagtcgtctt attaggagag ttcatgcatc cctgtgaaga tgacatcgtt tgtaaatgta
      541 ccacagaaga aaacaaggtg ccttacttca atgctcctgt ttatttagaa aacaaagaac
      601 aaatcgggaa agtggatgaa atatttggac aacttagaga tttttatttt tcagttaaat
      661 tgtcagaaaa catgaaggca tcttctttta aaaagctaca gaagttttac atagacccat
      721 ataagctgct gccactgcag aggtttctgc ctcggcctcc tggtgagaaa ggacctccca
      781 gaggtggtgg cggtggaggt ggtggtggca ggggaggtcg aggaggagga agaggaggcg
      841 gtggccgagg tggtggaaga ggtggtggtt ttagaggtgg aagaggagga ggtgggggct
      901 tcagaggagg aagaggagga ggcggcggat tccgaggaag gggacattag atgtccagtt
      961 ggcagacctg accacttctg tttccgctgc gtggcctgcc tctgctgtgg ctggcgtctg
     1021 tctggagcag tcttgagggt gccattctgt cagtggaact ggatcgccag catcgagtca
     1081 gatccagggg aacaggacag tcaattttgc tcagaaggag gagaacccct gctttgtaca
     1141 gtatctggca ctctgtgggt gcttaaagaa ccatgggact tttcatttga agcatatttg
     1201 gattttttaa ataaaatttt taatttcctt aacttatgtt tattgaacca aatctatttc
     1261 ttgaagtttg aagggctaaa agttttctga acatttttta catgaaagac tgacatgctg
     1321 tcttcatttt aaataaatac ttgcctgtcc caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaa
//
