LOCUS       XM_006234027            6409 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus GTPase activating protein and VPS9
            domains 1 (Gapvd1), transcript variant X1, mRNA.
ACCESSION   XM_006234027
VERSION     XM_006234027.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006234027.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006234027.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6409
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6409
                     /gene="Gapvd1"
                     /note="GTPase activating protein and VPS9 domains 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 77 ESTs, 2 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 175 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:311880"
                     /db_xref="RGD:1307479"
     CDS             169..4623
                     /gene="Gapvd1"
                     /codon_start=1
                     /product="GTPase-activating protein and VPS9
                     domain-containing protein 1 isoform X1"
                     /protein_id="XP_006234089.1"
                     /db_xref="GeneID:311880"
                     /db_xref="RGD:1307479"
                     /translation="MVKLDIHTLAHHLKQERLYVSSEKQLIQRLNADVLKTAEKLYRT
                     AWIAKQQRINLDRLIITSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSR
                     LRENPRLIASSLVAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFE
                     LKESDNPRRLLRRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETD
                     PNKLIERFSPAQQEKLFGEKGSDRFRQKVQEMVDSNEAKLVALVNKFIGYLKQNTYCF
                     PHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPIN
                     EVARFNLMQVGRLLQQLAMTGTEEGDPRTKNSLGKFDKGCVAAFLDVVIGGRAVETPP
                     MSSVNLLEGLSRTVVYISYSQLITLVNFMKSVMSGDQLKEDRMALDNLLANLPQAKPG
                     KSSSLDMTPYSTPQMSPATTPANKKNRLPIGQQLAAITAWDSSATNLTAHIPLVTPFA
                     TRSRSRSNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNMQ
                     LSDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVS
                     ELGAGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETW
                     STDVLGSDFDPNVDEDRLQEIAGAAAENVLGSLLCLPGSGSVLLDPCTGSTISETTSE
                     AWSVEVLPSDSEAPDLKQEERLQELESCSGLGSTSDDTDVREVSSRPSTPGLSVVSGI
                     SATSEDIPNKIEDLRSECSSDFGGKDSVTSPDVDDIAHGAHQLTSPPSQSESLLAMFD
                     PLSSHEGASAVVRPKVHYARPSHPPPDPPILEGAVGGNEARLPNFGSHVLTAAEMEAF
                     RQRHSYPERLVRSRSSDIVSCVRRPMSDPSWNRRPGNEELPPAAATGATSLVAAPHSS
                     SSSPSKDSSRGETEERKDSDDERSDRSRPWWRKRFVSAMPKAPIPFRKKEKQEKDKDD
                     LGPDRFSTLTDEPSPRLSAQAQVAEDILDKYRNAIKRTSPSEGALANDESTEVMGDGE
                     SAHDSPREELQNMSADDLPDSASQAAHPQDSALSYRDVKKKLRLALCSADSVAFPMLT
                     HSTRNGLPEHTDPEDNEIVCFLKVQIAEAINLQDKSLMAQLQETMRCVCRFDNRTCRK
                     LLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTTVCVRL
                     LLESKEKKIREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQDAQ
                     LAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLREA
                     PWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVL
                     IKANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTIDDRK"
ORIGIN      
        1 aggaggcaga gaaaccgact ggcgatctgt ggcggcggct gggcggcggt ggcagttcgc
       61 agcgagggcg acggctccga ggctgagtgg ccgtccggcg aggaccaggg cgccgtcctc
      121 cgcatgacct caccgtgatc aacctttgta ccttttccga attcaaagat ggtgaagcta
      181 gatattcaca cattggccca ccacctcaag caggagcgct tatatgtgag ctctgagaaa
      241 cagctcattc agaggctaaa tgcagatgtg ctgaagacag ccgagaagct gtatcggaca
      301 gcgtggattg caaagcagca gaggattaat ttggatcgtc tcattataac cagcgctgaa
      361 gcttcccctg ctgagtgttg ccagcatgct aagattttgg aagacacaca gtttgttgat
      421 ggatataagc aactgggatt tcaggaaaca gcctatggag aattcctgag tcggttaaga
      481 gagaatccgc gtcttattgc ctcctctttg gttgctggag aaaaactcaa tcaggagaac
      541 acacaaagtg ttatctacac tgtttttacc tccttgtatg gcaactgtat tatgcaagaa
      601 gatgaaagct acctccttca ggttttacga tacttgattg aattcgaact taaagaaagt
      661 gacaacccca ggcgcctttt gaggagagga acctgtgcct tcagcatctt atttaaactt
      721 ttttctgaag gactgttttc tgccaaactt ttccttacgg ctactttaca tgagccaatc
      781 atgcagctcc ttgtagaaga tgaggaccac ctggagacag atccaaacaa gctaatcgag
      841 aggttctctc cagcccagca ggaaaaactc tttggagaga aaggctcaga tagatttagg
      901 caaaaggttc aagaaatggt agattccaat gaggctaaac tagtggcttt ggtgaacaaa
      961 tttattggtt accttaagca aaatacgtac tgctttccac atagtttgag gtggattgta
     1021 tcacagatgt acaaaactct ttcttgtgta gacagattgg aggttgggga ggtcagagca
     1081 atgtgtacgg atcttctgtt ggcttgcttc atttgtcccg cagttgtcaa tccagaacag
     1141 tatggaataa tatctgatgc tcctattaat gaggtggcaa gatttaacct gatgcaggtt
     1201 ggccgccttt tgcagcagtt agcaatgact ggcactgagg aaggagatcc ccggaccaaa
     1261 aatagccttg ggaaatttga caaaggctgt gtcgctgctt tccttgatgt cgtaatcgga
     1321 ggccgtgcag tagagactcc accaatgtcc tctgttaatc ttctggaagg cttgagcaga
     1381 actgtggtgt atataagcta cagtcagctt attactctgg taaattttat gaagagtgtg
     1441 atgtctggag atcaactgaa agaagataga atggctcttg acaatttgtt ggcaaacttg
     1501 ccccaggcta agcccgggaa gagcagcagt ctagacatga ctccctacag cactcctcag
     1561 atgtctccag caaccactcc agccaataaa aagaatcggc tacctatagg acaacagtta
     1621 gcagccatca ctgcctggga ttcttcagcc accaatctta ccgctcacat tcctctagta
     1681 accccgtttg caactcggag ccgaagccga agtaatatgc taatggacct acatatggat
     1741 catgaagggt catctcaaga aaccatccag gaggtgcagc cagaagaggt gctggtcatt
     1801 tccttaggga caggtcctca gctcactcca gggatgatgt cagaaaatga ggttctaaac
     1861 atgcagcttt cggacggagg acaaggagat gtccctgttg atgaaaacaa actccacggt
     1921 aaacctgata aaaccttgcg cttttccctg tgcagtgata atctggaagg catatctgaa
     1981 ggtccttcca atcgctctaa ttcagtgtct tctctcgacc tggaaggaga gtctgtatct
     2041 gaacttgggg caggaccttc tgggagtaat ggagttgaag cactgcaact gttagaacac
     2101 gagcaagcta caacacaaga taatcttgat gataaactga ggaagtttga gattcgggat
     2161 atgatgggac taacagatga cagggacata tccgagacag tgagtgagac ctggagcacc
     2221 gatgtcctag gaagtgactt cgacccaaac gttgatgaag accgtttgca ggagattgca
     2281 ggtgcagcag cagagaatgt gctgggcagc ttgctgtgcc ttccaggttc cggctcagtt
     2341 ctccttgacc cttgcactgg ctcgaccata tcagagacca caagtgaagc ttggagtgta
     2401 gaggtgttgc ccagtgactc agaggctcca gacttaaagc aggaagagcg cctccaagag
     2461 ctggagagct gttctggact gggcagtaca tctgatgata cggatgtcag ggaggtcagt
     2521 tcccgcccca gcacaccagg cctcagtgtt gtgtccggca taagcgctac atcggaggat
     2581 attcccaata agatcgaaga cctgcgatct gagtgcagct ctgattttgg gggtaaagat
     2641 tctgtaacta gtccagatgt ggatgacata gcccatggcg cccaccagct gacctctcct
     2701 ccctctcagt cagagtctct gcttgccatg tttgacccac tgtcttcaca tgaaggggcc
     2761 tctgctgtgg taaggccgaa ggttcactat gcccggccct cgcatccacc tccagatcct
     2821 ccaatcctgg aaggtgcagt gggaggaaat gaagccaggc tgcccaactt cggttctcac
     2881 gttttaactg cagctgaaat ggaggcgttc aggcagaggc actcttaccc tgagagacta
     2941 gtgcgcagca gaagctctga tatagtgtct tgtgtgcggc ggcccatgag tgaccccagc
     3001 tggaaccgac gtccagggaa tgaagaactt ccaccagctg cagccactgg tgctacttct
     3061 ttggtggctg cacctcactc gtcatcttcg tccccgagta aggactcttc aagaggagag
     3121 actgaggagc gcaaggacag tgacgatgag aggtcagaca ggagcaggcc ttggtggaga
     3181 aagcgttttg tatcagctat gcctaaagct cctataccat ttagaaagaa agaaaaacaa
     3241 gaaaaagaca aagatgatct ggggcctgac agattctcaa cactcacaga cgagcccagc
     3301 cctaggctca gtgcacaagc tcaggttgcg gaagacattc tggacaaata ccgaaatgcc
     3361 attaaacgga ccagccccag tgaaggagca ctggcaaatg atgagagtac agaggtcatg
     3421 ggtgatggtg aaagtgctca cgattctcct cgtgaggagc tgcagaacat gtcagctgac
     3481 gacctcccag actctgcgag ccaagcagct caccctcagg actctgccct ctcttacaga
     3541 gatgtgaaaa agaagctgag gctcgcactt tgctctgcag actctgtggc cttccccatg
     3601 ctgactcatt caacaaggaa cggactgcca gagcacacag acccggaaga taatgaaatt
     3661 gtgtgcttct taaaagttca aatagctgaa gcaattaact tacaagataa gagcttaatg
     3721 gctcagcttc aagaaacaat gcgctgtgtc tgccgctttg acaataggac ttgtaggaag
     3781 ttgctggcat ccattgctga agactacaga aaaagagctc cgtatattgc gtatctcacc
     3841 cgctgtcggc aaggactgca gaccacacag gctcacctcg aaagactctt gcaaagagtt
     3901 ttgcgggaca aagaggtggc caatcggtat tttaccaccg tctgtgtgcg gttactgctt
     3961 gagagcaaag aaaagaagat cagggagttc attcaagact ttcagaaact tacggctgct
     4021 gatgataaga cggctcaagt ggaggatttc ctacagttcc tgtatggtgc gatggcgcag
     4081 gatgtcatat ggcagaatgc cagcgaggag cagctgcagg atgcccagct ggccatcgag
     4141 cggagcgtga tgaatcggat cttcaagctt gctttctacc ctaaccagga tggggacata
     4201 ctgcgtgacc aggttctgca tgaacacatc cagagattat ctaaagtagt gactgcaaac
     4261 cacagagctc tgcagatccc agaggtctat cttcgtgagg caccgtggcc atctgcacag
     4321 tcagaaatca ggactattag tgcttacaag acgccccggg acaaagtgca gtgcatcctg
     4381 agaatgtgct ccactatcat gaacctcctg agtctggcca atgaggactc tgtccccggg
     4441 gcagatgact ttgtccccgt gttggtgttt gtgttgataa aggcaaaccc accctgcctg
     4501 ctgtccaccg tgcagtacat cagcagcttc tatgccagct gtctgtctgg agaggagtcc
     4561 tactggtgga tgcagttcac tgcggccgtg gagtttatta aaaccatcga tgacagaaag
     4621 tgaccaagac caggcccacc aaggcagcag actgtagcca ggaaacagat ctctaagagt
     4681 gtgtagcagc ttccttgaaa gctgaacacc gttttgtcta aggctgtaca gatgtctcct
     4741 cacggctctt cctagcagac taacaagcta acagcaggtc ctcgctcctc tcggcctttc
     4801 tgagttgcct attttatttc ctgtccccac gtagagtagt actacaaaag ggaccatgtt
     4861 tttcaggtgt tttaaatttt taaaaaccac aacagaatct tttagggaac atctagatct
     4921 cggttcatga gttccctgtc cgtcgctttc atttctggaa agaacagtgt gcctcttcca
     4981 agtctctgtg tgagcgtgct cgctcaggag gccacctgca ctgagggtct cggagataca
     5041 gtctcctaag gaagagctga gaaggacatg tagatgtaat atatatttat atttgatgtg
     5101 atatgacatc ttcagactct aataaacaag agcagctgct gagagtagcg tgacattccc
     5161 tctgtgacat ggcttccttg acaaaactta agctgagctc aaaagcaaaa gcagagctat
     5221 ttattagtgt ggacacagtt tatcactctc catgtgtgca gtttgatggg gaagtcatgt
     5281 aggtgtgggc caccatggta tatgttgagc ctgcacactg gggcaggctc caccatgcat
     5341 tgcccagggc gagcagtgcg tggcagggtg cacgtgcgtc cttccttcac acctgctcac
     5401 cgagcctcag ccgtcctccg tctctgagga tggttcacat cgagtgcaca gaccaggaat
     5461 tcagtgaatg tcatttttta aaactcattt gtatcgtctg ctctactgat ccaggtttta
     5521 ctagtgttaa gcgattttga tcagccacac tattctatgg gaaatctatt ttggcggttt
     5581 ctgtgccttt attgccctct tctggaaaaa aaaaacaaaa aacaaaaaaa atcgtgtctg
     5641 tggtttggtc tgcgctgtac atcagtaatt aatcaggcat gggcgttggt gcctgagcgg
     5701 ctgcccaggg aggcacacca gagcttcaag cacaagtcct gtacataggc catcgcccat
     5761 ggtttcacct tgtatgtttc ctaaacctgt ttagcttttt tgacaaatgc tgcaatctca
     5821 tacttccgag gcccttgtgg cagcaataca ggcatcttct aaggggcccg tggcagccag
     5881 ccgtgagcag acgggtagag gccgtgtgct cccgctctga gtactgggcc acactgtgcc
     5941 aaaagaagct gggctttctc atgctcccct ctccttccct ttcatcccca agacgggttt
     6001 gcacaggcct gggagatgtg ctttctgcct gttagggaga gatcagaact aaactggcat
     6061 cacagacacc cgttcagatg ttggtcagga aatctgtgta cttcatgggc tgtcgtccac
     6121 cttgccttgg ggttagaagt cacttccctt ccttagtaca ttgcaagcca aactgtgact
     6181 cggttctgca gctagaaggg agtctgacat ctacgtcagc gctgattcaa taaatgttaa
     6241 gtcaacagaa gatttcgaat agttggaatt aattcattgt tatgggactt aacttgtaaa
     6301 tcaatgagag atttctctct ctctctctct ctctctctct ctctctctct gtaatggtag
     6361 ctaaatatat tccatgttat cactgtggaa ataaatatga agatgtgga
//
