LOCUS       NM_199393               2584 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus polypeptide N-acetylgalactosaminyltransferase 11
            (Galnt11), transcript variant 2, mRNA.
ACCESSION   NM_199393 XM_231275
VERSION     NM_199393.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2584)
  AUTHORS   Boskovski,M.T., Yuan,S., Pedersen,N.B., Goth,C.K., Makova,S.,
            Clausen,H., Brueckner,M. and Khokha,M.K.
  TITLE     The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia
            type and laterality
  JOURNAL   Nature 504 (7480), 456-459 (2013)
   PUBMED   24226769
REFERENCE   2  (bases 1 to 2584)
  AUTHORS   Young,W.W. Jr., Holcomb,D.R., Ten Hagen,K.G. and Tabak,L.A.
  TITLE     Expression of UDP-GalNAc:polypeptide
            N-acetylgalactosaminyltransferase isoforms in murine tissues
            determined by real-time PCR: a new view of a large family
  JOURNAL   Glycobiology 13 (7), 549-557 (2003)
   PUBMED   12651884
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1 and BC062004.1.
            
            On Sep 15, 2012 this sequence version replaced NM_199393.1.
            
            Transcript Variant: This variant (2) lacks an exon in the 5' UTR,
            compared to variant 1. Both variants 1 and 2 encode the same
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062004.1, SRR26360186.2140050.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                JAXUCZ010000004.1  10604909-10604974   c
            67-2578             BC062004.1         1-2512
            2579-2584           JAXUCZ010000004.1  10571464-10571469   c
FEATURES             Location/Qualifiers
     source          1..2584
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q11"
     gene            1..2584
                     /gene="Galnt11"
                     /note="polypeptide N-acetylgalactosaminyltransferase 11"
                     /db_xref="GeneID:311952"
                     /db_xref="RGD:735097"
     exon            1..178
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            179..511
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..2043
                     /gene="Galnt11"
                     /EC_number="2.4.1.41"
                     /note="galNAc-T11; pp-GaNTase 11; polypeptide GalNAc
                     transferase 11; protein-UDP
                     acetylgalactosaminyltransferase 11; UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase 11;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 11 (GalNAc-T11);
                     :polypeptide N-acetylgalactosaminyltransferase 11"
                     /codon_start=1
                     /product="polypeptide N-acetylgalactosaminyltransferase
                     11"
                     /protein_id="NP_955425.2"
                     /db_xref="GeneID:311952"
                     /db_xref="RGD:735097"
                     /translation="MMGSVTIRYFCYGCLFTSATWTVLLFIYFNFSEVTQPLRNVPIK
                     GSGPHGPFPKKFYPRFTRGPGRVLEPQFKANRMDDLMNNNIEDPDKGLSKSSSELGMI
                     FNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRGKSYPTDLPTASVVICF
                     YNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLPAKVKVI
                     RNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVID
                     IISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSDLGGADSATAPIRSPTMAGGLFAMN
                     RQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFRKRRPYGSPEG
                     QDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKTKSFGNISERVELRKKLGCQSFKWYLD
                     NVYPEMQVSGPKARLQQPVFINRGPKRPRVLLRGRLYHLQTNKCLVAQGRSSQKGGLV
                     LLKACDYGDPTQVWIYNEEHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFG
                     KNNRLYQVSVGQCLRVVDQMDQKGYVGMAICDGSSSQQWRLEG"
     exon            512..635
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            636..802
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            803..928
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1178
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1296
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1449
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1668
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1773
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1774..1911
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2584
                     /gene="Galnt11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcggaggcg ggggcatgcg tgccgtgacg tgagccctgg agcgcggctc cgtaaggctg
       61 cgtgtcgtgg gccgcgttgc gcggcgcggc tcgtgcggct cggcccgggc tgtggcggga
      121 gcgaagatgc cacagcccgt gccccggagc gccgctatcc cggcctgcgg gtgtcgcggg
      181 aactgaaaat ggcctttgag ctatgctagg tctatgatgg gcagtgtcac aattcgatat
      241 ttctgctacg ggtgcctctt tacatctgct acctggacag ttctgctttt catttatttt
      301 aacttcagtg aagtgactca gccccttagg aatgtgccca tcaaggggtc tgggccccat
      361 gggccgtttc ccaaaaaatt ctacccacgt ttcactcgag gtccaggccg agtattagag
      421 ccacagttca aagcaaacag aatggacgat ttgatgaata ataacattga agatccagat
      481 aaaggcctct caaaatcttc ctctgagcta ggtatgattt tcaatgaacg tgatcaggaa
      541 ttgagagacc tgggctacca gaaacacgcc tttaatatgc tcattagtaa ccgcttgggg
      601 taccacagag acgtgccaga caccaggaat gcagagtgta gggggaagtc ctacccaact
      661 gacctgccaa ctgctagcgt tgttatctgt ttctacaacg aagctttttc tgccttgttg
      721 cggactgtgc acagtgttgt ggaccgcacg ccggcacacc ttctccatga gatcatcctc
      781 gtggatgaca gcagtgactt tgatgattta aaaggagaac tagatgagta catccaaaga
      841 tacctgcccg caaaggtcaa ggtcataaga aatatgaagc gagagggact gatccgagga
      901 agaatgattg gagcagccca cgctacagga gaagtcctgg tcttcctgga cagccactgc
      961 gaagtgaatg tgatgtggtt acagcccctt ctggccatca tccttgaaga cccacataca
     1021 gtggtgtgcc ctgtgattga catcatcagt gctgacacac tcgcttacag ttcatcccca
     1081 gtggttcggg gaggtttcaa ctgggggctg cacttcaagt gggatctagt tcctgtatct
     1141 gacctgggag gcgcagacag tgccacagcc ccaatacggt cacctacaat ggccggagga
     1201 ctgtttgcca tgaacagaca gtatttcaat gatcttggac agtatgacag tggcatggat
     1261 atctggggag gagaaaatct ggaaatctca tttcggatct ggatgtgcgg cggcaagctc
     1321 ttcatcatcc cttgctcaag agtcgggcac atttttcgga aaaggcgacc gtatggatct
     1381 cctgaaggcc aggacaccat gacacacaac tcgctgagac tggcacatgt gtggctggat
     1441 gagtacaagg agcagtattt ttccttaaga cctgatttga agaccaaaag ctttgggaat
     1501 atcagcgagc gtgttgaatt gaggaagaaa ctgggctgtc agtcgttcaa gtggtatttg
     1561 gataatgttt accctgagat gcaggtgtct ggtccgaagg ccagactgca gcagcccgtg
     1621 ttcatcaaca gaggaccgaa gcgccccaga gtcctgctgc gtggaaggct ctaccacttg
     1681 cagaccaaca aatgcctggt ggcccagggc cgctccagcc agaaaggagg cctggtgctg
     1741 cttaaggcct gtgactacgg agacccaact caggtctgga tttacaacga agagcatgaa
     1801 ttgatcttaa acaacctcct ttgcctcgac atgtcagaaa cccgctcgtc agaccctcct
     1861 cgactcatga agtgccacgg gtcaggaggg tcgcagcagt ggacctttgg gaagaacaat
     1921 cggctgtacc aagtgtcggt tgggcagtgc ctgagagttg tggaccagat ggatcagaag
     1981 ggctacgtcg gcatggcgat ctgtgatggc tcctcttccc aacagtggcg cctagaaggc
     2041 taaaggtggg cgggccctgg ctgggggcaa ctaattcacc tggttttgtc acgcctgcca
     2101 taagtcaagg tgctttgtaa aagatgttgt tgactgcaaa aggcaagaac ctgctgcagg
     2161 gcagccatct cagggtcttc actggaattg gttaatttcc gggctgctgt taagggattc
     2221 ttatttatcc agggaagaca gaaaataact gtaaagagtt ggtctaccta ggataaaccc
     2281 aggaagtagg tgtttctgtt catattcatg tttctcttgt tctcccttgg agatggaatg
     2341 gtttctgtct taacaggaac ttgtcacaat ttcctttcgt agaggacttc ataagagatt
     2401 ttttttctac ttttatcatg tttaatgttc caaatagatt ttaaaaactg gttgagtgca
     2461 tattactttt agcttcagaa gataacatgt atatttaaga ggcatctaac tattataaat
     2521 tattttgatg acttactagg ctgtctacat taaataaagg atctctttga tcatttaaca
     2581 agga
//
