LOCUS       NM_130742               4686 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus polypeptide N-acetylgalactosaminyltransferase 10
            (Galnt10), mRNA.
ACCESSION   NM_130742
VERSION     NM_130742.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4686)
  AUTHORS   Perrine,C.L., Ganguli,A., Wu,P., Bertozzi,C.R., Fritz,T.A.,
            Raman,J., Tabak,L.A. and Gerken,T.A.
  TITLE     Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc
            T10), involved in mucin-type O-glycosylation, has a unique
            GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in
            ppGalNAc T1 or T2
  JOURNAL   J Biol Chem 284 (30), 20387-20397 (2009)
   PUBMED   19460755
REFERENCE   2  (bases 1 to 4686)
  AUTHORS   Raman,J., Fritz,T.A., Gerken,T.A., Jamison,O., Live,D., Liu,M. and
            Tabak,L.A.
  TITLE     The catalytic and lectin domains of UDP-GalNAc:polypeptide
            alpha-N-Acetylgalactosaminyltransferase function in concert to
            direct glycosylation site selection
  JOURNAL   J Biol Chem 283 (34), 22942-22951 (2008)
   PUBMED   18562306
REFERENCE   3  (bases 1 to 4686)
  AUTHORS   Cheng,L., Tachibana,K., Zhang,Y., Guo,Jm., Kahori Tachibana,K.,
            Kameyama,A., Wang,H., Hiruma,T., Iwasaki,H., Togayachi,A., Kudo,T.
            and Narimatsu,H.
  TITLE     Characterization of a novel human UDP-GalNAc transferase,
            pp-GalNAc-T10
  JOURNAL   FEBS Lett 531 (2), 115-121 (2002)
   PUBMED   12417297
REFERENCE   4  (bases 1 to 4686)
  AUTHORS   Ten Hagen,K.G., Bedi,G.S., Tetaert,D., Kingsley,P.D., Hagen,F.K.,
            Balys,M.M., Beres,T.M., Degand,P. and Tabak,L.A.
  TITLE     Cloning and characterization of a ninth member of the
            UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family,
            ppGaNTase-T9
  JOURNAL   J Biol Chem 276 (20), 17395-17404 (2001)
   PUBMED   11278534
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 27, 2022 this sequence version replaced NM_130742.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.25967.1,
                                           SRR21887622.435080.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               JAXUCZ010000010.1  42322519-42322794
            277-379             JAXUCZ010000010.1  42398313-42398415
            380-518             JAXUCZ010000010.1  42402477-42402615
            519-685             JAXUCZ010000010.1  42413993-42414159
            686-871             JAXUCZ010000010.1  42445770-42445955
            872-1055            JAXUCZ010000010.1  42449573-42449756
            1056-1173           JAXUCZ010000010.1  42451886-42452003
            1174-1281           JAXUCZ010000010.1  42458834-42458941
            1282-1503           JAXUCZ010000010.1  42461855-42462076
            1504-1620           JAXUCZ010000010.1  42462940-42463056
            1621-1770           JAXUCZ010000010.1  42464523-42464672
            1771-4686           JAXUCZ010000010.1  42465172-42468087
FEATURES             Location/Qualifiers
     source          1..4686
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..4686
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /note="polypeptide N-acetylgalactosaminyltransferase 10"
                     /db_xref="GeneID:170501"
                     /db_xref="RGD:69409"
     exon            1..276
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1929
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /EC_number="2.4.1.41"
                     /note="galNAc-T10; pp-GaNTase 10; polypeptide GalNAc
                     transferase 10; protein-UDP
                     acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide
                     N-acetylgalactosaminyltransferase 10; GalNAc-T9;
                     UDP-N-acetyl-alpha-D-galactosamine: polypeptide
                     N-acetylgalactosaminyltransferase 9;
                     UDP-N-acetyl-alpha-D-galactosamine:polypeptide
                     N-acetylgalactosaminyltransferase 10 (GalNAc-T10)"
                     /codon_start=1
                     /product="polypeptide N-acetylgalactosaminyltransferase
                     10"
                     /protein_id="NP_570098.1"
                     /db_xref="GeneID:170501"
                     /db_xref="RGD:69409"
                     /translation="MRRKEKRLLQAVALALAALVLLPNVGLWALYRERQPDGSPGGSG
                     AAVAPEAIQELHSRQKKTLFLGAEQRLKDWHNKEAIRRDAQRVGNGEQGKPYPMTDAE
                     RVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSS
                     LLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLI
                     RTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRY
                     ETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGG
                     YDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKR
                     VAEVWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFY
                     PPVEPPAAAWGEIRNVGTGLCTDTKHGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWR
                     EDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDC
                     SESDHRIFMNTCNPSSLTQQWLFEHTNSTVLENFNRN"
     exon            277..379
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            380..518
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            519..685
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            686..871
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            872..1055
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1173
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1174..1281
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1503
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1620
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1770
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..4686
                     /gene="Galnt10"
                     /gene_synonym="Galnt9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagttggag cggggccggc gccgcggccg cttctgctgg ccgaactgct gccgccgccg
       61 ggcggacggg cggacgcgca aagccggggg cgggcgcggc ggggcggacc ggccccgatg
      121 aggcgcaaag agaagcggct cttgcaggcg gtggcgctgg ctctggcggc ccttgtcctg
      181 ctgcccaacg tggggctctg ggctctgtac cgcgagcggc agccggacgg cagtcctggg
      241 ggatccgggg cggcggtggc cccggaggcg atacaggaat tacacagtcg gcaaaaaaag
      301 acacttttct tgggagctga acaaaggctg aaggactggc ataacaagga ggctatcagg
      361 agggatgcgc agcgcgtagg aaatggagaa caggggaagc cttaccccat gaccgatgct
      421 gagagagtgg accaggcata ccgggaaaac ggatttaaca tctacgtcag tgataaaatc
      481 tccctgaatc gctctctccc cgatatccgg cacccaaact gcaacagtaa gctttacctg
      541 gagacgcttc ccaacaccag catcatcatc cctttccaca acgagggctg gtcctcactg
      601 ctgcgcaccg ttcacagcgt gctcaaccgc tcgcccccag aactcgtggc ggagatcgtg
      661 ttggtcgatg acttcagtga ccgagaacac ctgaagaagc cactagaaga ctacatggcc
      721 ctgttcccca gcgtgaggat tctccggaca aagaaacggg aaggcctgat aaggacccga
      781 atgctggggg cttcggccgc caccggagat gtcatcacat tcttagattc acactgtgaa
      841 gccaacgtca actggctccc ccctttgctt gaccgcatcg ctcggaaccg aaagaccatc
      901 gtgtgcccaa tgattgacgt catcgaccac gatgacttcc ggtacgagac acaagccggg
      961 gacgccatgc ggggtgcctt tgactgggaa atgtattaca aacgaatccc aatccctcca
     1021 gagctgcaga aggcggaccc tagtgaccca tttgagtctc ctgtgatggc cggagggctg
     1081 ttcgctgtgg atcggaaatg gttctgggag ttgggcggat acgaccctgg cttggagatc
     1141 tggggagggg agcagtatga gatctccttc aaggtgtgga tgtgtggggg ccgcatggag
     1201 gacatcccct gctccagagt gggccacatc tacaggaagt atgtgcccta caaggtccct
     1261 gccggagtca gcctggccag gaacctgaag agagtggctg aggtgtggat ggatgagtat
     1321 gcagaataca tctaccagcg cagaccggaa taccgccacc tctcagctgg agacgttgtg
     1381 gcccagaaaa aactccgagg ctccctcaac tgtaagagct tcaagtggtt tatgaccaaa
     1441 attgcctggg acctgcccaa gttctaccca cctgtggaac ccccggctgc ggcctggggg
     1501 gagattcgca atgtgggcac aggactgtgc acagacacga agcatggcac attaggctcc
     1561 ccgctgaggc ttgagacctg cattcggggc cgtggggagg ctgcctggaa cagcatgcag
     1621 gtcttcacct tcacctggcg ggaggacatc cggcctggag accctcaaca taccaagaag
     1681 ttctgcttcg acgctgtttc ccacaccagc ccagtcaccc tctatgactg ccacagcatg
     1741 aagggcaacc agctgtggaa ataccgcaag gacaagaccc tgtaccaccc tgttagcggc
     1801 agctgcatgg actgcagcga aagtgaccac aggatcttca tgaacacctg caatccctcc
     1861 tccctcaccc agcagtggct ctttgaacat accaactcca cggtcttaga aaatttcaac
     1921 cgaaactgag tccttagacc tccttgacaa gcccctcagg ttgctgtggc actcatagac
     1981 cttcctcctg tgggagaaga ggcatccgtg ggcaccaagg tgctgggcca agtggcttgg
     2041 gacagagggt tcttgaagta cttgcgtggt ggggccatgg ggagaagaga ccacacgaac
     2101 agctctccaa gaaggtagag cctgcttaca tagtagcaga gttcaccagc ctgtcagcat
     2161 tgtctcctaa aggttagggt tgaaccagaa aatcagtcct acgaggttgc ctagcccttg
     2221 ggctactgcc agacaagaca gtgccctaga aggaaaggtg gtattggcct tgggacagat
     2281 tttaagcctg tgtgctagct actggcaagg atgtctgccc gtgctgaggg gagactgcca
     2341 gtactgccca gcttctatgt tggtccaggg cactgagagc ccactgggac ctcagagtgc
     2401 tctgtagcta gcgctggcca gcaaccagac aaggagcttc tttctctgca gccaaatgta
     2461 aggggtgtct tccctggctc tctgggtatt tcagatgccc gttctagtta cagggctatc
     2521 cgggtaccag gttttcgggg ctggttcagc tggctcagta gacctccaga ccaaacagct
     2581 cccagccaat gcttccaaag ccctttctct gtgctttcct tggcagctcc cctgccttgg
     2641 agaggaacgg gtgctgcgag atgctcacct ccagagttcc cctgggggtg gcggcttccc
     2701 ccagataatg accgttgtgg ttccaacctc acagaaccct ggagtttctg aaaagtgctg
     2761 caaacaaaga tgagccatgg catgcgtggg cacagagcgc aagcatccag gtgtcaggca
     2821 acccctcacc cgagcggagg cagtgggaca ccggaagctt tggtacaacc cagtgccctg
     2881 tgaggagtga ggacgtcccc tttaacccca tgtctcaaat gagaacttac cctccaagga
     2941 tgtggttact tgaccttgtc atttgccagt gaagtaactg agatgtggtc ctggggacag
     3001 agccctgcct tagagatgct gggatcaggg tcatccagtc ctcaggtcgg ccagatggct
     3061 ggtgtagagt cacctccatg caacccctgc gctgtcacag ctcccttgtg gatttctagt
     3121 gtccttttcc atatgagcat tctacctgac aaatgaccag ctgggaagga gtcagagggg
     3181 gtggggggtg agcgtctaga atccagtggg gacacgtgtt gcagccaagg ggagtcgagt
     3241 cctcggagag caatgcggcc tcatttcaat aaaaaccgtg ccttttacaa agagaaaatg
     3301 cagtcgagca gctgactccc taaacttgaa ccacttctta gtgccttgct agacagacgg
     3361 gtgggggggg gggggcttac gcaggtccta tgagcagact gggtgtcttt atatctgact
     3421 tcaagcagaa agtgctaggc ttggagcaga actgagaccc agaggccccc cacagtaggg
     3481 aaactgccta tctgtgcagc cctccctgag actggacagc tctagtagcc tacaagttct
     3541 agagacctga caaccctgtg ggtaggaggt gctgatcccc ccagaagtgc tctgcccgtc
     3601 cctcgctatc aggggcgagc tgtatttcca ggtgatgtta agccggtggt taaagcagat
     3661 gctgccacaa gccatccctg gccttgcttg ccccattcat ttccattctc atctggtttg
     3721 ccccctcctc cagtggtcac ttcctctgag ctcacctcag catctgtgac tgctggactc
     3781 tgaccttaaa gcataagact tgaggaggtg tgtcacagga aggaccaggc gggcctagtg
     3841 gctggctaca ggtacttcaa tccccacctt gttttggctt caggtgtgga aacccttgtc
     3901 cagaagagtc aggtttctac tctgcacagg caggaaggcc tgtggacacg ccacagccaa
     3961 gcaacaagcc aggcagctgg cctctcttcc tccaaagctt tacttcaagg ctaagactgc
     4021 aaaacaaaat gcggttagaa agtcacctcc caaatgttcc agaaacattt ttggaatgca
     4081 gtgtccttgc tacgaggcct ttgtgtggca agctgtctta ccctgtcctg ccacctggag
     4141 tgtctggctt taaaagcagc cggcaatggt ggaccttcag ttgtggcggg agctgctctg
     4201 atgggcaagc ctagtggatt cccagagtca gcaccacgac tccccttcag tccttcctgt
     4261 tacgcttctc cctgcgtgta gccaagaagt ggtggcgtgt ttaactgaag acaggcagtg
     4321 ggaaagggac aaggagtgca gttccaccct gcatccggtc aacacttgct gctggtgctt
     4381 tctacgacaa atcctagtca tattttggtt taaggttttg atgctgaatc agggccctgc
     4441 tgcccccatt gggtgagagt aatagctgtt tcgagatctt aacaggttcc actctgctct
     4501 gacgggaagg ctggggtccc ctggggtggg ggggctgcag gcagggaagc tgggcactga
     4561 gacagggttc tgtgggggaa gcccaagacc acccacctct cctggaagag tgagctctgt
     4621 aaaagatgac ttaccatgtt cagttgtgac tgtgattgtt caataaatct ccagagtttc
     4681 tctaaa
//
