LOCUS       NM_001013919            1797 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus galactokinase 2 (Galk2), mRNA.
ACCESSION   NM_001013919 XM_215827
VERSION     NM_001013919.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1797)
  AUTHORS   Ai,Y., Basu,M., Bergsma,D.J. and Stambolian,D.
  TITLE     Comparison of the enzymatic activities of human galactokinase GALK1
            and a related human galactokinase protein GK2
  JOURNAL   Biochem Biophys Res Commun 212 (2), 687-691 (1995)
   PUBMED   7542884
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083716.1.
            
            [WARNING] On May 3, 2024 this sequence was replaced by
            NM_001013919.2.
            
            On Apr 1, 2005 this sequence version replaced XM_215827.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083716.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1797
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..1797
                     /gene="Galk2"
                     /note="galactokinase 2"
                     /db_xref="GeneID:296117"
                     /db_xref="RGD:1308691"
     exon            1..129
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1453
                     /gene="Galk2"
                     /EC_number="2.7.1.157"
                     /note="galNAc kinase"
                     /codon_start=1
                     /product="N-acetylgalactosamine kinase"
                     /protein_id="NP_001013941.1"
                     /db_xref="GeneID:296117"
                     /db_xref="RGD:1308691"
                     /translation="MAAEDPATRRVQVAEHPRLLKLKEMFNSKFGSTPKFYVRAPGRV
                     NIIGEHIDYCGYSVLPMAVEQDMLIAVGPVKTQTLQLANTDPLYPDFSTTANNICIDK
                     TQPLWHNYFLCGFKGIQEHFGLTQLPGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLT
                     VLGMRLSKVELAEICAKSERYIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLP
                     SGAVFVIANSCVEMNKAATSHFNVRVMECRLAAKVLAKHKGLQWDKVLRLEEVQSELG
                     ISLEEMLLVTEDALHAEPYSREEICKCLGISLEELRTQILSPNTQGELTFKLYQRAKH
                     VYSEAARVLQFKQVCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF
                     GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAYYQGNMSRLAREKHSLFATKPGG
                     GALVFLEA"
     exon            130..218
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            219..342
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            343..433
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            434..580
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            581..679
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            680..832
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1043
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1245
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1246..1774
                     /gene="Galk2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctattcctg ccactttaat ctcgtgatcc ttagctgtgc tgcacttctg gaaaccgcat
       61 agggatctag caaaatatgg ctgcggagga ccccgccacg cgacgagtcc aagtggcaga
      121 acaccccaga ttgctgaagc taaaagagat gttcaactct aagtttgggt ccacacccaa
      181 gttttatgtt cgagccccag gaagagtgaa cataataggt gagcacatag attactgtgg
      241 gtactctgtt ctccccatgg ctgtggagca ggacatgcta atagctgtgg gacctgtgaa
      301 aacccagact ctccaactgg ccaatacaga ccccttgtat ccagacttca gtactacagc
      361 taataacatc tgtatcgaca agacccaacc tctatggcac aactacttcc tatgtggatt
      421 taagggaatt caggaacact ttggtcttac tcagctgcct ggaatgaatt gcctggtgga
      481 tggaaatata cccccgagtt caggcctctc cagctccagt gctctggttt gctgcgctgg
      541 gttagtgact ctcacagtgc tgggaatgag actatccaag gtggaacttg cagaaatctg
      601 tgccaagagt gagcgttaca taggcaccga aggcggaggc atggaccagt ccatatcatt
      661 tcttgcagaa gaaggaactg ccaagttaat agaatttagt cctctgagag cgactgatgt
      721 gaagctcccc agtggagcag tcttcgtgat tgccaacagc tgtgtggaaa tgaacaaggc
      781 agccacttca catttcaacg tcagggtgat ggagtgtcgg ctggcggcaa aggtccttgc
      841 taaacacaaa ggcttgcaat gggataaagt cctgaggcta gaggaagtac aaagcgaact
      901 aggaattagt ctggaagaga tgctattggt cacagaggat gcccttcatg cagaacccta
      961 ctcaagggag gagatctgta agtgcctggg aattagcctg gaggaactcc gcacccaaat
     1021 cctgagtcca aatactcaag gcgaactcac cttcaagctc taccagcggg ccaagcatgt
     1081 gtacagtgag gctgcacgtg tgctgcagtt caagcaggtg tgcgaagcag caccagacaa
     1141 cgccgtccag ctgctgggcg agctgatgaa ccagagccac agaagctgcc gggacatgta
     1201 tgagtgcagc tgcccggaat tggatcagct agtggacatc tgccggaagt ttggggccaa
     1261 aggctcacga cttactggag ccggatgggg aggctgcact gtgtccctcg tgcctgctga
     1321 cacgctgtcc agcttcctcg caagcgtgca tgaggcttac taccagggga acatgtcccg
     1381 cctggctcgg gagaagcata gcttgtttgc taccaagcct ggaggtgggg ccttggtttt
     1441 ccttgaggcc taaacaatgt caaacatctc agagaaacta tttcaggcat tctggagctg
     1501 gcaggacttc ctgtgccaca gtaaatcagc cccctttcta ttttgtgttg tgaagtatga
     1561 ttgctattat caaggtgcat ttccaaagaa atggaaaacg aggcttcgtg atgacttctt
     1621 ttccttcttc catgtatttt tatgaatcag agccaaggat atgcttacat ctttgaagta
     1681 tgattaagat ttattgatgt gaagatttta aagatgaaca gcaaaatgta cttttagttg
     1741 tacactctcc tccaattaaa ttgatagagc tgaaaaaaaa aaaaaaaaaa aaaaaaa
//
