LOCUS       NM_031733               6127 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus gamma-aminobutyric acid type A receptor subunit
            theta (Gabrq), mRNA.
ACCESSION   NM_031733 XM_006229516 XM_343838
VERSION     NM_031733.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6127)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   2  (bases 1 to 6127)
  AUTHORS   Pape,J.R., Bertrand,S.S., Lafon,P., Odessa,M.F., Chaigniau,M.,
            Stiles,J.K. and Garret,M.
  TITLE     Expression of GABA(A) receptor alpha3-, theta-, and epsilon-subunit
            mRNAs during rat CNS development and immunolocalization of the
            epsilon subunit in developing postnatal spinal cord
  JOURNAL   Neuroscience 160 (1), 85-96 (2009)
   PUBMED   19249336
  REMARK    GeneRIF: Our findings suggest that various combinations of GABA(A)
            alpha3-, theta- and epsilon-subunits may be assembled at a regional
            and developmental level in the brain.
REFERENCE   3  (bases 1 to 6127)
  AUTHORS   Sinkkonen,S.T., Hanna,M.C., Kirkness,E.F. and Korpi,E.R.
  TITLE     GABA(A) receptor epsilon and theta subunits display unusual
            structural variation between species and are enriched in the rat
            locus ceruleus
  JOURNAL   J Neurosci 20 (10), 3588-3595 (2000)
   PUBMED   10804200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On or before Sep 2, 2022 this sequence version replaced
            XM_006229516.4, NM_031733.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.3096703.1,
                                           SRR26360190.1781317.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16418986, SAMN16418988
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-134               JAXUCZ010000021.1  155738436-155738569
            135-316             JAXUCZ010000021.1  155738669-155738850
            317-405             JAXUCZ010000021.1  155740820-155740908
            406-473             JAXUCZ010000021.1  155744921-155744988
            474-694             JAXUCZ010000021.1  155746016-155746236
            695-777             JAXUCZ010000021.1  155747810-155747892
            778-912             JAXUCZ010000021.1  155748373-155748507
            913-1065            JAXUCZ010000021.1  155748878-155749030
            1066-1322           JAXUCZ010000021.1  155749525-155749781
            1323-6127           JAXUCZ010000021.1  155750419-155755223
FEATURES             Location/Qualifiers
     source          1..6127
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq37"
     gene            1..6127
                     /gene="Gabrq"
                     /note="gamma-aminobutyric acid type A receptor subunit
                     theta"
                     /db_xref="GeneID:65187"
                     /db_xref="RGD:68331"
     exon            1..134
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            135..316
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     CDS             168..2090
                     /gene="Gabrq"
                     /note="gamma-aminobutyric acid A receptor, theta;
                     gamma-aminobutyric acid (GABA) A receptor, theta;
                     gamma-aminobutyric acid type A receptor theta subunit;
                     gamma-aminobutyric acid (GABA-A) receptor, subunit theta;
                     gamma-aminobutyric acid receptor subunit theta;
                     gamma-aminobutyric acid (GABA) receptor, theta"
                     /codon_start=1
                     /product="gamma-aminobutyric acid receptor subunit theta
                     precursor"
                     /protein_id="NP_113921.2"
                     /db_xref="GeneID:65187"
                     /db_xref="RGD:68331"
                     /translation="MGIRGMLRAAALLLLIRTWLAESNDPSPTPKFHFELSSSMPEVI
                     LDLFNCKNCANEAVVQKILDRVLSTYDVRLRPNFGGAPVPVSISIYVSSIEQISEINM
                     DYTITMFLHQTWKDTRLAYYETNLNLTLDYRMHEKLWVPDCYFVNSKDAFVHDVTAEN
                     RVFQLHPDGTVQYGIRLTTTAACSLDLQKFPMDKQSCKLEVESYGYTVEDIVLSWEDD
                     NAIHITDELHIPQYTYLGRTITSKEVYFYTGSYMRLIVKFQVQREVRSYLVQVYWPTV
                     LTTILSWISFWMNYGSSAARVTIGLTSILVLTTIDSHMRDKLPHISCIKAIDIYILVC
                     LFFVFLSLLEYVYINYLFFSQAPRRNHRRCRKPRRVVARYRYQEVVVANVQDGLINVE
                     DRVEDRAGPLPDSPMQAHLASQESLGSLMFTSEEAQLATSESLSLLSSASSQVQLATG
                     ESLGDLPSTSEQTLPDYTIHFHGFLTNDSILPIKIRSHSDALGDEDSEESLSSEESYG
                     HGGSPTGRLKLQISQRCVQEASWDIDKIESLQDDISIKSSWLGLDEQRKGDADSIWSL
                     TDEELMACDQEKDSSSSSESEESCSPSPGCSFNEGFSFQLFNPNRVPKVDRWSRFLFP
                     LSFGLFNVVYWLYHIY"
     exon            317..405
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            406..473
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            474..694
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            695..777
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            778..912
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1065
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1322
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..6127
                     /gene="Gabrq"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagcggtgc cagacgaagc gcaccttgca gtggcacgcc ctgtggaccg ctgcgtgggg
       61 aagagctgct gcggagctgc tgttctttca ggccctgggc tccggaacga ccccttactc
      121 cctgcttcct tcagctgtcc gctgcggtcc ccaagagcac cgcagccatg ggcatccgag
      181 gcatgctgcg agccgctgcg ctcctgctgc tcattaggac ttggctggca gagagtaacg
      241 accccagtcc caccccaaaa ttccacttcg agctctcctc cagcatgcct gaagtcatcc
      301 tggatctctt caactgcaaa aattgtgcaa atgaagctgt tgttcaaaag attttggaca
      361 gggtcctgtc aacatatgat gtccgactga gaccaaattt tggaggagca cctgtgcctg
      421 tgtcaatatc tatctatgtc tccagtattg aacagatctc agaaataaac atggactata
      481 ccatcacaat gtttctgcat cagacttgga aggacacgcg cttagcttac tatgagacca
      541 acctgaacct gactctggac tatcggatgc atgagaagct ctgggtccct gactgctact
      601 ttgtgaatag caaagatgcc tttgtgcatg atgtaactgc ggagaatcgt gtatttcaac
      661 ttcacccaga tgggacagtg caatatggca tccgacttac cacaacagca gcctgttccc
      721 tggatctgca aaaattccct atggacaaac aatcctgcaa gctggaggtg gagagctatg
      781 gctacactgt cgaagacatt gtgttatcct gggaagatga taatgccatc cacattactg
      841 acgagctaca catccctcag tacacctacc tggggaggac aattaccagc aaggaggtgt
      901 acttctacac aggctcctac atgcgcctga tagtgaagtt ccaggttcag agggaagtcc
      961 gcagttacct tgtgcaggtc tattggccca cagtcctcac caccattctc tcctggatat
     1021 cattttggat gaactatggt tcctctgcag ccagggtaac tattggacta acttcaatcc
     1081 ttgtcctgac taccatcgac tcacatatgc gggataaact cccccatatt tcctgtatca
     1141 aagccattga catctacatc cttgtgtgcc tgttcttcgt tttcctgtcc ctgctggagt
     1201 atgtctacat caactacctt ttcttcagcc aagcacctcg gcgtaatcac aggagatgca
     1261 ggaaacccag gagagttgtt gcccgatacc gctaccaaga agtggtggta gcaaatgtgc
     1321 aggatggcct gataaatgtg gaagacagag tggaagacag agctggtccc cttcctgaca
     1381 gccccatgca ggctcatctg gcaagccagg aaagtctagg atctttgatg ttcacttcag
     1441 aggaggctca actggctact tcagaaagcc tcagcctact ctcgtctgcc tcaagccagg
     1501 tccaattggc cactggagaa agcctgggtg atctgccctc cacctctgag caaacactgc
     1561 ctgactatac cattcacttt catggttttc tcactaatga cagtattctc cccatcaaaa
     1621 tccgcagcca ttctgatgcc ctgggtgatg aagactccga agaaagccta agctctgagg
     1681 agagctatgg ccatggaggc agccccactg gaaggctcaa gctccagatt agccagaggt
     1741 gtgtgcaaga agcaagttgg gacattgata agattgagag cttacaggat gacatcagta
     1801 tcaagagcag ctggcttggc cttgatgaac aacgcaaagg ggatgctgac agtatctgga
     1861 gccttactga tgaggagctc atggcctgtg accaagagaa ggacagtagc agtagctcag
     1921 agtctgagga gagttgctcc ccaagccctg ggtgctcctt caatgaaggg ttctcttttc
     1981 agctctttaa ccctaaccgg gtccctaagg ttgacaggtg gtcccgtttc ctcttccctc
     2041 tttcctttgg gttgttcaat gtggtttact ggttatacca catctattag tttctcatac
     2101 accacagcag cagggatatg atgatgtgtt tcctttgtgt tcattcagtt ttatttttcc
     2161 ctcttcccct ttttcatttt atctggcaaa gtttcttttt ttggtttggg gatggggttg
     2221 ttttgtttgg aagggtcaat caaatccatt gggcactttt ctttattatg aggtggggag
     2281 gagatagaga aaacatgtaa ccagagaaga aagagtgagg aagacttgga gataaattgc
     2341 acattgattt cctcctacca gaaaattctc acctttcact ttaaacagtc catccaccta
     2401 gaaatgccta tggaagtatt tagaggaaag agaagaccca tgctgaggaa tgaggataat
     2461 ctggttcaca aatattcctg ggactttcat tttttagtcc cctcaaaatg ttgaaattgc
     2521 ttttgcatca ctttttcctt cctcctgggt gccatgcacc ctgtctgtct gcatggggag
     2581 aagaagtcaa accaagttgg cctggggtat gcagaggagg ggctaggcat ggcttggcta
     2641 ttctgacaaa gttgggaatt atttgtaagt actttgtact ttgagtgtag agttgtgata
     2701 cagaagtggg aagggcagct gggtaggaag gactgccaac gagatatagc agagtgagtg
     2761 agaaagcatg ctttccagca ggggtatgca tgacaggggg aagattgtca gctgaagtct
     2821 gcacatgttc agctattccc ttttaagtta ctagaccttc ccttgtccat atttcccctt
     2881 cacgttgcct gacagtaggg acttagtact tctgttcaat tatgagttag gtttctatca
     2941 attgctgggt tgattactag ttacagtaga cacacaactt ggtgagtaag cattagttga
     3001 gaaagttcag atttgctatt ccaccatcgg cctagaatag catatgaaca actactgtga
     3061 atctatatac taatcctttc tgtttgtcta gtgcatagta agtgtcaacg aggtccctga
     3121 cccatcacat cgttggatcc tcacaggagc cctgtgagcc agggaagaaa agacaccttg
     3181 tccccagtgt tccaaggaca atgtggagct tgtgtgccat gcttaaagat gcttgttctt
     3241 tctccttatc tgcctaactc tcaactagct gcccattccc tgtgctcaaa ggggcacccc
     3301 tacagaatct acctgttggt ctgctaagct cactggacag cacctggagc atctctatat
     3361 gaagaggcta ctgaccagcc actgaacatg gagcccactc agcaggattc ctgatgagag
     3421 taggatgagc ctgcacacca actttctagg aagcaccagc tcattgatgg aggtcatgag
     3481 ggagcttttc caagcattca acctataacc ccctccctct ataggcagcc tctccttcag
     3541 cccacccacc tccttaacta tacttctatg tgtatatatt tctgtgtatc tctgaggatg
     3601 agtgtgtatg tatccaggta ggtctaagtg ctagccatac aaccatttga gacgctgtac
     3661 tactgtcaat ctacattagt gtatatgagt gcatatctgc gctgtgtggg tgaatagtat
     3721 gtatgcatct gtatgagagt gtcacttgtg tacttatatt agcgtagctg aatgcattct
     3781 gtatatatgc atggaatgtg tctgtctgta tacctgtgtt tgtcaaactt agttggtgta
     3841 aaaggacata catcaaaggg aaaccacatg tgttccctgt aagaggtttt tgtagaaaca
     3901 gcatgactct agtgacatgt tttggcacag tggggaaaat cttatttagc tggactgatt
     3961 gactgttctc ttcagttcta gagagccagg gggacctact aggaaagtaa atttgtagct
     4021 aatcctagga cagactctgc tgcttgacta ggccccaaaa cctatcttgt gtttggagtt
     4081 caaatgtttc tttctttaac tcaattcagg gaaagagtca gagaattaaa aatggaaagg
     4141 agcaccaggt attgaataga tggtctcggt attgtctctt ctccatgcat aggcacaatt
     4201 ctagcctttt atacatacac acagacacac acccactcca tcacacgtgc acatatacat
     4261 accaggagca cccatgctct gagttctatt tacaggcatg tccagacata tacatgcaca
     4321 agtaaacatg tacacacaca cattttaaaa caactcaaaa caaggaaatt ctaccaaaat
     4381 atctatgatt gtctattttg ttttaggaac ccagcacaaa gagctccaaa ttaatgggag
     4441 agcagagagt tctcatctgg aatctgagca ttcattggat gtgtgcttgt atttggagac
     4501 ctttaacctt gtagagttgg acacatcact ggagttacaa agagagatta cagtgatggg
     4561 aacaaagaaa cggcagagag gccagttgta aatatccaca tagatatagc ataccctaaa
     4621 agactatttt gccctaatgt gctgcaatga aagcagttaa actctactgc gattcatact
     4681 atgtgaagtg acatgtcaaa gtaccatgga ggtctggcaa tgacagcttt tcaggaactt
     4741 gaatcttctg gttttttcat gactatggtt tttcttactt gaaagttgcc agatcttccc
     4801 ttgtattctg tgtgtggttc atctttttca agccctgtct cctgctgctc ccagcccttt
     4861 tccagccata caggcatacc ctctctatct ggctgcctat atctcctctg gaacttcctc
     4921 cttcactaag tagttgtgac agtgcagagc atctgaacag tgctcctggg gttcaacctg
     4981 tctaacagct tggacagaag gaagagcctt actaagtctg ggatggaaca accccacttt
     5041 actactctat tctgccttgc cttgccctct cccctccccc tagaattcct gtctgagaaa
     5101 gacaccagct ttctgtcttg ccaatgcatc attttattgt agaaatatgt ggtgtatttc
     5161 ctgcccagtt tggtttgcat tgtggggtat ctctgcacaa tgggtctcaa tggagtttgc
     5221 ccaatgtatt cttacaattt gtatcatcct cattcatagc aaggttgcaa actcttgata
     5281 tacttagaac caactttggc tgagattgtg accattccta atgaggtttc cttactctgt
     5341 atatacagca gcaacacttt caagctatta agtactgaag gcattcacta agcactccat
     5401 ctgcatgata ccctgtgata gcaagcagga actctagcta ttctacaacc cagcatctta
     5461 agcaattgta acttgtccta ctgaaagtgc agtgtgtttg tgtttgttgt atagtgtcct
     5521 gagattaata tgagtctaca ttatcagtgt tgggttttca ggggagggag ggaatgatgt
     5581 taaaatatcg gatagttcaa taatgaaata ggccagctgg tcagggccat ccatgtagaa
     5641 ctctgtcaga atttgcaccc actatcatac tagactgtgt ccctgggatc agtattcatt
     5701 agcaaaggta aagataccag aattttgcac agtaatagaa aatgacttca gataattcca
     5761 gaggattctt tcaatggtaa ttaagtcatt ggctcccatt ctgggagcat atgaactatg
     5821 ataaagtcac atacatacag atcttcggta gtggtgttag gccaagacag taaaaggtaa
     5881 gaaaagagaa ttaccaacag ccaggtaacc taggtgacct gacctgcaag ggccacagta
     5941 gcagagcctt actagataag tgggtgctca cgttgaactc attaaatgac attcctgtga
     6001 aaaaggacct tgaccggtcc tgacttcaag aaagtgaaac gtgaaagagc atatgattat
     6061 gcttctgaaa atgaggcttt aaaacatgta aatagcaaac agcaaaataa agatctatac
     6121 tagcaaa
//
