LOCUS       NM_001044294            1719 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus GABA type A receptor associated protein like 1
            (Gabarapl1), mRNA.
ACCESSION   NM_001044294 XM_001072692
VERSION     NM_001044294.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1719)
  AUTHORS   Mandell,M.A., Jain,A., Arko-Mensah,J., Chauhan,S., Kimura,T.,
            Dinkins,C., Silvestri,G., Munch,J., Kirchhoff,F., Simonsen,A.,
            Wei,Y., Levine,B., Johansen,T. and Deretic,V.
  TITLE     TRIM proteins regulate autophagy and can target autophagic
            substrates by direct recognition
  JOURNAL   Dev Cell 30 (4), 394-409 (2014)
   PUBMED   25127057
REFERENCE   2  (bases 1 to 1719)
  AUTHORS   Popovic,D., Akutsu,M., Novak,I., Harper,J.W., Behrends,C. and
            Dikic,I.
  TITLE     Rab GTPase-activating proteins in autophagy: regulation of
            endocytic and autophagy pathways by direct binding to human ATG8
            modifiers
  JOURNAL   Mol Cell Biol 32 (9), 1733-1744 (2012)
   PUBMED   22354992
REFERENCE   3  (bases 1 to 1719)
  AUTHORS   Seguin-Py,S., Lucchi,G., Croizier,S., Chakrama,F.Z., Despouy,G., Le
            Grand,J.N., Ducoroy,P., Boireau,W., Boyer-Guittaut,M., Jouvenot,M.,
            Fraichard,A. and Delage-Mourroux,R.
  TITLE     Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting
            protein
  JOURNAL   Biochimie 94 (3), 748-758 (2012)
   PUBMED   22120110
REFERENCE   4  (bases 1 to 1719)
  AUTHORS   Behrends,C., Sowa,M.E., Gygi,S.P. and Harper,J.W.
  TITLE     Network organization of the human autophagy system
  JOURNAL   Nature 466 (7302), 68-76 (2010)
   PUBMED   20562859
REFERENCE   5  (bases 1 to 1719)
  AUTHORS   Kanki,T.
  TITLE     Nix, a receptor protein for mitophagy in mammals
  JOURNAL   Autophagy 6 (3), 433-435 (2010)
   PUBMED   20200478
REFERENCE   6  (bases 1 to 1719)
  AUTHORS   Mansuy,V., Risold,P.Y., Glauser,M., Fraichard,A. and Pralong,F.P.
  TITLE     Expression of the GABAA receptor associated protein Gec1 is
            circadian and dependent upon the cellular clock machinery in GnRH
            secreting GnV-3 cells
  JOURNAL   Mol Cell Endocrinol 307 (1-2), 68-76 (2009)
   PUBMED   19524128
  REMARK    GeneRIF: Gec1 expression is dependent upon the circadian clock
            machinery in GnRH-expressing neurons.
REFERENCE   7  (bases 1 to 1719)
  AUTHORS   Tolle,F., Risold,P.Y., Mansuy-Schlick,V., Rossi,E.,
            Boyer-Guittaut,M., Fraichard,A. and Jouvenot,M.
  TITLE     Specific regional distribution of gec1 mRNAs in adult rat central
            nervous system
  JOURNAL   Brain Res 1210, 103-115 (2008)
   PUBMED   18423580
  REMARK    GeneRIF: the putative role in the trafficking of receptor GABA(A)
REFERENCE   8  (bases 1 to 1719)
  AUTHORS   Wang,Y., Dun,S.L., Huang,P., Chen,C., Chen,Y., Unterwald,E.M.,
            Dun,N.J., Van Bockstaele,E.J. and Liu-Chen,L.Y.
  TITLE     Distribution and ultrastructural localization of GEC1 in the rat
            CNS
  JOURNAL   Neuroscience 140 (4), 1265-1276 (2006)
   PUBMED   16650615
REFERENCE   9  (bases 1 to 1719)
  AUTHORS   Simonsen,A., Birkeland,H.C., Gillooly,D.J., Mizushima,N., Kuma,A.,
            Yoshimori,T., Slagsvold,T., Brech,A. and Stenmark,H.
  TITLE     Alfy, a novel FYVE-domain-containing protein associated with
            protein granules and autophagic membranes
  JOURNAL   J Cell Sci 117 (Pt 18), 4239-4251 (2004)
   PUBMED   15292400
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105627.1.
            
            On Aug 24, 2006 this sequence version replaced XM_001072692.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105627.1, FQ213425.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1719
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1719
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /note="GABA type A receptor associated protein like 1"
                     /db_xref="GeneID:689161"
                     /db_xref="RGD:1596143"
     exon            1..266
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..530
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /note="GEC-1; glandular epithelial cell protein 1;
                     gamma-aminobutyric acid (GABA(A)) receptor-associated
                     protein-like 1; GABA(A) receptor-associated protein like
                     1"
                     /codon_start=1
                     /product="gamma-aminobutyric acid receptor-associated
                     protein-like 1"
                     /protein_id="NP_001037759.1"
                     /db_xref="GeneID:689161"
                     /db_xref="RGD:1596143"
                     /translation="MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDL
                     DKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEED
                     YFLYVAYSDESVYGK"
     exon            267..345
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /inference="alignment:Splign:2.1.0"
     exon            346..464
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /inference="alignment:Splign:2.1.0"
     exon            465..1694
                     /gene="Gabarapl1"
                     /gene_synonym="Gec1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccaggtccct ctctggacgt ttggtcacgt agtgcggcga ccagagcgtg ggagctgacg
       61 cgggtggagc gattgtgata aggctgacat tgactggggg tggccagacg ggagacgcgg
      121 tcaacagcgc gcgcagcagg ccccgtccgg ggagccccta catcctgcga tccatcatga
      181 agttccagta taaagaggac caccccttcg aatatcggaa aaaggaaggt gaaaaaataa
      241 ggaagaaata cccggacagg gtgccggtca tcgtggagaa ggctcctaaa gccagggtcc
      301 ccgatctgga taagaggaag taccttgtgc cctccgacct cactgttggc cagttctact
      361 tcttaatccg gaagaggatc cacctgagac ctgaggacgc cttattcttc tttgtcaaca
      421 acactatccc tcccaccagt gctaccatgg gacagctgta tgaggacaac catgaggaag
      481 actattttct gtatgtggcc tacagtgatg aaagtgtcta cgggaaatga ggcagaagcc
      541 cagcagatgg gagcgcctgg acttgggggt aggggagggg tgcgtgtggg acttggggaa
      601 ccagagggag ggctcccaac catggaggag acgcaaggtg aagacatcag gaaacatcac
      661 accgcacacg ctgtcgtctt ttattcacga gctcaattgt tactttttct ctgcttcccc
      721 agcccaggaa gaacttgtgt tggattggct gtgagagcgg gatggggaca acacgatcca
      781 cagccttgct gtgtgtgagc tttctttcgt gtagtttcat cagaggtttg ggagggggca
      841 ggtgaccgat agagaagaag acagttcagc agcaactctc gtcactttgg gcagaggttt
      901 gactttgtgg catttgtaca agccaccagg caaaggggga aagaatgctg taggggacca
      961 tacctaaggg accaaaagat acccactgtt actgaagcat ttcgaccttt gacctctgcc
     1021 ctaattcctt cctctcctag tccttttcct ccgcccaggt gtcatagcac cgccccagtt
     1081 gtggcagtag acattcgcac ggacatttag atggagtcct cttggaaaat agggctgttc
     1141 gcaatgtggt tgtgattgcc agcagtttgg atggcgttaa agtggagttc agggttgaac
     1201 atgtcccgct cttcttccca caagaacctt ggactttcag gagcctcagg atcagtcctc
     1261 tagcatttcc ttcacctttc tcatggacag ggacagcgtg tctgtgtgtg gagggtcggg
     1321 gttacaaggt aagctaggtc acacacctgc cgctcgtcct ccccctgctg cagtctctta
     1381 ggtctcactc gcactggaat gcaaagcgat ggccagctgt ctccctccgc ggcatctgct
     1441 atcgagagaa gatggaacga ggggcgccag agtttcatgg gggctttact cattcatttc
     1501 atttagggac tctgttgggg ggaggggcag gaatcgcatt cacacatgac atttcaattc
     1561 atctctacaa atgaagagcg tcctccccgt tgggagctat ctgtatgttc gctttgtcgg
     1621 catcaggttc tgggactttg aagtcaattg ctgtcaggcc agggaaataa aataattgct
     1681 taccttaaaa aatcaaaaaa aaaaaaaaaa aaaaaaaaa
//
