LOCUS       NM_001271185            2820 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus frizzled class receptor 7 (Fzd7), mRNA.
ACCESSION   NM_001271185 XM_002727203 XM_002730032
VERSION     NM_001271185.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2820)
  AUTHORS   Voloshanenko,O., Gmach,P., Winter,J., Kranz,D. and Boutros,M.
  TITLE     Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting
            of receptor gene families
  JOURNAL   FASEB J 31 (11), 4832-4844 (2017)
   PUBMED   28733458
REFERENCE   2  (bases 1 to 2820)
  AUTHORS   Egea-Jimenez,A.L., Gallardo,R., Garcia-Pino,A., Ivarsson,Y.,
            Wawrzyniak,A.M., Kashyap,R., Loris,R., Schymkowitz,J., Rousseau,F.
            and Zimmermann,P.
  TITLE     Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports
            Frizzled 7 trafficking and signalling
  JOURNAL   Nat Commun 7, 12101 (2016)
   PUBMED   27386966
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2820)
  AUTHORS   Lu,T.Y., Lin,B., Li,Y., Arora,A., Han,L., Cui,C., Coronnello,C.,
            Sheng,Y., Benos,P.V. and Yang,L.
  TITLE     Overexpression of microRNA-1 promotes cardiomyocyte commitment from
            human cardiovascular progenitors via suppressing WNT and FGF
            signaling pathways
  JOURNAL   J Mol Cell Cardiol 63, 146-154 (2013)
   PUBMED   23939491
REFERENCE   4  (bases 1 to 2820)
  AUTHORS   Wheeler,D.S., Barrick,S.R., Grubisha,M.J., Brufsky,A.M.,
            Friedman,P.A. and Romero,G.
  TITLE     Direct interaction between NHERF1 and Frizzled regulates
            beta-catenin signaling
  JOURNAL   Oncogene 30 (1), 32-42 (2011)
   PUBMED   20802536
REFERENCE   5  (bases 1 to 2820)
  AUTHORS   Ueno,K., Hazama,S., Mitomori,S., Nishioka,M., Suehiro,Y.,
            Hirata,H., Oka,M., Imai,K., Dahiya,R. and Hinoda,Y.
  TITLE     Down-regulation of frizzled-7 expression decreases survival,
            invasion and metastatic capabilities of colon cancer cells
  JOURNAL   Br J Cancer 101 (8), 1374-1381 (2009)
   PUBMED   19773752
REFERENCE   6  (bases 1 to 2820)
  AUTHORS   Li,C., Chen,H., Hu,L., Xing,Y., Sasaki,T., Villosis,M.F., Li,J.,
            Nishita,M., Minami,Y. and Minoo,P.
  TITLE     Ror2 modulates the canonical Wnt signaling in lung epithelial cells
            through cooperation with Fzd2
  JOURNAL   BMC Mol Biol 9, 11 (2008)
   PUBMED   18215320
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2820)
  AUTHORS   Dufourcq,P., Leroux,L., Ezan,J., Descamps,B., Lamaziere,J.M.,
            Costet,P., Basoni,C., Moreau,C., Deutsch,U., Couffinhal,T. and
            Duplaa,C.
  TITLE     Regulation of endothelial cell cytoskeletal reorganization by a
            secreted frizzled-related protein-1 and frizzled 4- and frizzled
            7-dependent pathway: role in neovessel formation
  JOURNAL   Am J Pathol 172 (1), 37-49 (2008)
   PUBMED   18156211
REFERENCE   8  (bases 1 to 2820)
  AUTHORS   Vincan,E., Darcy,P.K., Farrelly,C.A., Faux,M.C., Brabletz,T. and
            Ramsay,R.G.
  TITLE     Frizzled-7 dictates three-dimensional organization of colorectal
            cancer cell carcinoids
  JOURNAL   Oncogene 26 (16), 2340-2352 (2007)
   PUBMED   17016432
REFERENCE   9  (bases 1 to 2820)
  AUTHORS   Staal,F.J., Meeldijk,J., Moerer,P., Jay,P., van de Weerdt,B.C.,
            Vainio,S., Nolan,G.P. and Clevers,H.
  TITLE     Wnt signaling is required for thymocyte development and activates
            Tcf-1 mediated transcription
  JOURNAL   Eur J Immunol 31 (1), 285-293 (2001)
   PUBMED   11265645
REFERENCE   10 (bases 1 to 2820)
  AUTHORS   Tanaka,S., Akiyoshi,T., Mori,M., Wands,J.R. and Sugimachi,K.
  TITLE     A novel frizzled gene identified in human esophageal carcinoma
            mediates APC/beta-catenin signals
  JOURNAL   Proc Natl Acad Sci U S A 95 (17), 10164-10169 (1998)
   PUBMED   9707618
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Sep 7, 2012 this sequence version replaced
            XM_002730032.1, XM_002727203.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26643429.33898.1,
                                        SRR26643298.49020.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2820              JAXUCZ010000009.1  68425538-68428357
FEATURES             Location/Qualifiers
     source          1..2820
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q31"
     gene            1..2820
                     /gene="Fzd7"
                     /note="frizzled class receptor 7"
                     /db_xref="GeneID:100360552"
                     /db_xref="RGD:2321905"
     exon            1..2820
                     /gene="Fzd7"
                     /inference="alignment:Splign:2.1.0"
     CDS             363..2081
                     /gene="Fzd7"
                     /note="frizzled family receptor 7; frizzled-7;
                     rCG22430-like"
                     /codon_start=1
                     /product="frizzled-7 precursor"
                     /protein_id="NP_001258114.1"
                     /db_xref="GeneID:100360552"
                     /db_xref="RGD:2321905"
                     /translation="MRGPGTEASHSPLGLCALVLALLGALPTDTGAQPYHGEKGISVP
                     DHGFCQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFL
                     CSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEIC
                     VGQNTSDGSGGAGGSPTAYPTAPYLPDPPFTAMSPSDGRGRWSFPFSCPRQLKVPPYL
                     GYRFLGERDCGAPCEPGRANGLMYFKEEERRFARLWVGVWSVLCCASTLFTVLTYLVD
                     MRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGYRTVAQGTKKEGC
                     TILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTI
                     TILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRT
                     IMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTWLLQTCKS
                     YAVPCPPGHFSPMSPDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRLSHSS
                     KGETAV"
ORIGIN      
        1 tttgaagggt aaccggagac gcttgttgct cgtcgccgca gagaaagccg caccgttacg
       61 tctcggcggg gagggtaagg cgacaccccc ctcggtcccc ccactccagg cccaggagtt
      121 tgaacccctg gaggccgcgt gagtgccacg cggaggcggc tgcggcgccc cctcggctgg
      181 cggcctcgcc cccgctgtgc aggcacccta gcaccctcgg ctccgcgccg cccacggccc
      241 ggccccggcg ccgggaggac tctcatgcgc cgggcgcggc ggcgcctccc tgcatccaag
      301 ccgctcccca gcgccccgtc tttttcctcc agctgagaac gccgctgcac tctcggccgg
      361 cgatgcgggg ccccggcacg gaggcgtcgc actcgcccct gggcctctgt gccttggtgc
      421 ttgctcttct gggcgcgctg cccacggaca ccggagctca accataccac ggcgagaaag
      481 gcatctcggt accggaccac ggcttctgcc agcccatctc catcccgttg tgcacggata
      541 ttgcctacaa ccagaccatc ctgcccaacc tgctgggcca cacgaaccaa gaggacgcgg
      601 gcctcgaggt gcaccagttc taccctctgg taaaggtgca gtgttctccc gagctgcgct
      661 tcttcttatg ctctatgtac gcacccgtgt gcaccgtgct cgaccaagcc attcctccgt
      721 gccgttcctt gtgcgagcgc gcccgacagg gctgcgaggc gctcatgaac aagttcggtt
      781 tccagtggcc ggagcggctg cgctgcgaga acttcccggt gcacggcgcc ggcgagatat
      841 gcgtggggca gaacacgtcc gacggctccg ggggcgcagg cggtagtccc accgcctacc
      901 ctactgctcc ctacctgcca gacccgcctt tcactgcgat gtccccctca gatggcagag
      961 gccgctggtc tttccccttc tcttgcccgc gtcagctcaa ggtccccccc tacctgggct
     1021 accgtttcct aggcgagcgt gactgcggtg ccccgtgtga gccaggccgt gctaacggcc
     1081 tcatgtactt taaagaagag gagagacgtt tcgcccgcct ctgggtaggt gtgtggtcag
     1141 tgctgtgctg tgcctcgacg ctcttcacgg tgctcaccta cctagtggac atgcgtcgct
     1201 tcagctatcc agagcgaccc attatcttcc tgtcgggctg ctacttcatg gtggcagtgg
     1261 cgcacgtggc gggcttcctg ctagaggacc gtgccgtgtg cgtggagcgc ttctcggacg
     1321 atggctaccg cacggtggcg cagggcacca agaaggaggg ctgcaccatc ctcttcatgg
     1381 tgctttactt cttcggcatg gccagctcca tctggtgggt cattctttcc ctcacttggt
     1441 tcctggcagc tggcatgaag tggggccacg aggccatcga ggccaactcg cagtactttc
     1501 atctggccgc gtgggctgtg ccagcggtca agacaatcac catcttggcc atgggccagg
     1561 tggatggtga cctactcagt ggagtgtgct acgtgggcct gtctagtgtg gatgcactgc
     1621 ggggcttcgt gctggcgccc ttgttcgtct acctcttcat cggtacgtcc ttcctgttgg
     1681 ccggctttgt gtctctcttt cgcatccgca ccatcatgaa gcacgatggc accaagacgg
     1741 agaagctgga gaagctcatg gtgcgcattg gcgtcttcag cgtgctctac acggtcccag
     1801 ccaccatcgt gctggcgtgc tacttttacg agcaggcctt ccgcgagcac tgggagcgca
     1861 cctggctcct gcagacctgc aagagctacg ctgtgccctg ccccccgggc cacttctcgc
     1921 ccatgagccc cgactttaca gtcttcatga tcaagtacct gatgaccatg atcgtgggca
     1981 tcactaccgg cttctggatc tggtcgggca agaccctgca gtcatggcgt cgcttctacc
     2041 acagactcag ccacagcagc aagggggaga ctgcggtatg agccctggtc cttaccccac
     2101 ccttgccact tctactcttt cgcaggagga gaggcatggt agggaaagaa ctgttgggtg
     2161 gggggcttgt ttctgtaaac tccctgcccc ctccactgag ctttaatctg gaagtgagaa
     2221 gttatttgga ggtgagaaga aatttggggt gagagatggt cttgagagga ggcccaaatg
     2281 aaaaggcgaa ggcagtggct gaaaagactc ctggctaaga cttgcaggac gatgctaact
     2341 gtgaaagaca tgggctggct agggtctaag ggaaaggctg agatcagaga ctgagttcgt
     2401 caggcaccag agatgagcca gggttgtgag tccaatcccc tgctgcaagg caagtggctg
     2461 tcctcactcc agtgagggag ggggtgaggg tgggggagga taccgctctg tctgcagcct
     2521 aggctttgtg gccaaaatgg ggaccccctg cggtgccctt gtcaagcggt ggtcaaacca
     2581 taatctcttt tcactggggc caaactggag cccagatggg ttaatttcca gggtcagacc
     2641 ccttacagtc ctcctcccgg accccctccc gcctgttttt ccttccctac tcctttcaag
     2701 tctagtaaaa taagcatttg gaaggcgggg gagtcctgtc tgctagagtc ctaacgcaga
     2761 gatgcccgag aaggtttcgg agaggaggcc aaagagccga gtggtagata cagtctgcta
//
