LOCUS       NM_001271192            3196 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus frizzled class receptor 10 (Fzd10), mRNA.
ACCESSION   NM_001271192 XM_003751177 XM_003752587
VERSION     NM_001271192.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3196)
  AUTHORS   Zhan,Y., Wen,Y., Zheng,F., Du,L.J., Chen,T.Y., Shen,X.L., Wu,R. and
            Tang,X.G.
  TITLE     MiR-26b-3p Promotes Intestinal Motility Disorder by Targeting FZD10
            to Inhibit GSK3beta/beta-Catenin Signaling and Induce Enteric Glial
            Cell Apoptosis
  JOURNAL   Mol Neurobiol 61 (3), 1543-1561 (2024)
   PUBMED   37728849
  REMARK    GeneRIF: MiR-26b-3p Promotes Intestinal Motility Disorder by
            Targeting FZD10 to Inhibit GSK3beta/beta-Catenin Signaling and
            Induce Enteric Glial Cell Apoptosis.
REFERENCE   2  (bases 1 to 3196)
  AUTHORS   Voloshanenko,O., Gmach,P., Winter,J., Kranz,D. and Boutros,M.
  TITLE     Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting
            of receptor gene families
  JOURNAL   FASEB J 31 (11), 4832-4844 (2017)
   PUBMED   28733458
REFERENCE   3  (bases 1 to 3196)
  AUTHORS   Fukukawa,C., Nagayama,S., Tsunoda,T., Toguchida,J., Nakamura,Y. and
            Katagiri,T.
  TITLE     Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled
            homologue 10 in human synovial sarcoma
  JOURNAL   Oncogene 28 (8), 1110-1120 (2009)
   PUBMED   19137009
REFERENCE   4  (bases 1 to 3196)
  AUTHORS   Fukukawa,C., Hanaoka,H., Nagayama,S., Tsunoda,T., Toguchida,J.,
            Endo,K., Nakamura,Y. and Katagiri,T.
  TITLE     Radioimmunotherapy of human synovial sarcoma using a monoclonal
            antibody against FZD10
  JOURNAL   Cancer Sci 99 (2), 432-440 (2008)
   PUBMED   18271942
REFERENCE   5  (bases 1 to 3196)
  AUTHORS   Nagayama,S., Fukukawa,C., Katagiri,T., Okamoto,T., Aoyama,T.,
            Oyaizu,N., Imamura,M., Toguchida,J. and Nakamura,Y.
  TITLE     Therapeutic potential of antibodies against FZD 10, a cell-surface
            protein, for synovial sarcomas
  JOURNAL   Oncogene 24 (41), 6201-6212 (2005)
   PUBMED   16007199
REFERENCE   6  (bases 1 to 3196)
  AUTHORS   Wang,Z., Shu,W., Lu,M.M. and Morrisey,E.E.
  TITLE     Wnt7b activates canonical signaling in epithelial and vascular
            smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5
  JOURNAL   Mol Cell Biol 25 (12), 5022-5030 (2005)
   PUBMED   15923619
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On or before Sep 7, 2012 this sequence version replaced
            XM_003752587.1, XM_003751177.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the genome
            assembly. The genomic coordinates used for the transcript record
            were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3196              JAXUCZ010000012.1  33734364-33737559   c
FEATURES             Location/Qualifiers
     source          1..3196
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q13"
     gene            1..3196
                     /gene="Fzd10"
                     /gene_synonym="Fzd10-ps1"
                     /note="frizzled class receptor 10"
                     /db_xref="GeneID:363913"
                     /db_xref="RGD:1583825"
     exon            1..3196
                     /gene="Fzd10"
                     /gene_synonym="Fzd10-ps1"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..2122
                     /gene="Fzd10"
                     /gene_synonym="Fzd10-ps1"
                     /note="frizzled homolog 10, pseudogene 1; frizzled family
                     receptor 10; frizzled-10"
                     /codon_start=1
                     /product="frizzled-10 precursor"
                     /protein_id="NP_001258121.1"
                     /db_xref="GeneID:363913"
                     /db_xref="RGD:1583825"
                     /translation="MQHPGPRLWLMLQVMMGSCAAISSMDLERPGDGKCQPVEIPMCK
                     DIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVST
                     PIPACRVMCEQARLKCSPIMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAPNNGSDEPS
                     RGSGMFPPLFRPQRPHSAQEHPLKDGGPGRAGCDNPGKFHHVEKSESCAPLCTPGVDV
                     YWSRDDKRFAVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSV
                     GYIIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLT
                     WFLAAGRKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDV
                     NALTGFVLVPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGVFSL
                     LYTVPATCVIACYFYERLNMDYWKMLATQHKCKTNNQTKTADCLMTTSIPAVEVFMVK
                     VSMLLVVGITSGVWVWTSKTLQSWQQVCSRGLKRKSRRKPASVVTSAGIYKKAQHPQK
                     PHLGKYELPAQPSACV"
ORIGIN      
        1 tcccgggacg ccgagctcaa aacagctgcg ggcgccggga gggaggagct ccggggcccg
       61 gggccacggt gcgcccgcgc tgccccactg aggtccgcga tcgcgcgcgc ccggaagaag
      121 aggccaaagt ttgcgcgcag agccgcgctc gctctgccgt attgtttgca aacttcgttc
      181 ccctcccccg ccgccccgga ctcggccgag gccgctcgcc caccgcggtg gccccgggcg
      241 ccgcgagcgc tccagccaga ctggatgggc atgcgcgggg gcccgagccg gggcgcggag
      301 ccgcgggcag cagcaacagc cggtgcccgg gagcggcggc cctgagcggc gcagggacac
      361 cgcgggcgcc accatgcaac acccgggccc acgcctgtgg ctgatgctgc aggtaatgat
      421 gggttcgtgc gcggccatca gctccatgga cttagagcgc cctggagacg gcaagtgcca
      481 gccggtggag attcccatgt gcaaggacat cggctacaac accacccgca tgcccaacct
      541 gatgggccac gagaaccagc gggaggcggc catccaactg catgagttcg cgccgctcgt
      601 ggagtacggc tgccacggcc acctccgctt cttcttgtgc tcgctgtacg cgcccatgtg
      661 caccgagcag gtctccacac ccatccctgc ttgccgggtc atgtgcgagc aggcccggct
      721 caagtgctcg ccgatcatgg agcagtttaa attcaggtgg ccggactccc tggattgcag
      781 caaactcccc aacaagaacg atcccaacta cctgtgcatg gaggcaccca acaacggctc
      841 cgatgagccc agccgtggct ctggcatgtt ccctccgctc ttcaggcccc agaggcccca
      901 cagcgcgcaa gagcacccac taaaggacgg gggtcccggg cgcgcaggct gtgacaaccc
      961 aggcaagttc caccacgtgg agaagagcga atcctgcgca ccgctctgca ctccgggggt
     1021 ggatgtgtat tggagccgcg acgacaagcg cttcgctgtg gtctggctgg ccatctggtc
     1081 cgtgctgtgt ttcttctcca gcgccttcac cgtgctcacc ttcctcatcg acccatcacg
     1141 cttcaggtac cccgaacgtc ccatcatctt tctctccatg tgctactgcg tttattctgt
     1201 gggctatatc atccgcctct tcgcgggcgc ggagagcatt gcctgcgacc gggacagtgg
     1261 gcagctgtat gttatccagg aagggctgga gagcacgggc tgtaccttag tcttcttggt
     1321 actttactac ttcggcatgg ccagctcttt atggtgggtg gttctcaccc tcacttggtt
     1381 cctggctgct ggcaggaagt ggggccatga ggccattgaa gccaacagca gctactttca
     1441 cctggcagcc tgggccatcc cggctgtgaa gaccatcttg atcctggtga tgcgcagggt
     1501 ggcaggggat gagctcactg gtgtgtgtta tgtgggcagc atggatgtca atgctctgac
     1561 cggcttcgtg ctggtcccgc tggcttgcta cctagtcatc ggcacttcct tcatcctgtc
     1621 tggctttgtg gctttattcc acatccggag ggtgatgaaa acaggtgggg agaacacgga
     1681 caagctggag aagctcatgg tacgcatagg ggtcttctcc ctcctctaca ccgtgccggc
     1741 cacctgtgtg attgcttgtt acttttatga acgcctcaac atggattact ggaagatgct
     1801 ggccacccag cacaagtgta aaacgaacaa tcagaccaag acagccgact gcctgatgac
     1861 cacctccatc cctgctgtgg aggtcttcat ggtcaaagtg tccatgcttc tggtggtggg
     1921 cattaccagt ggggtgtggg tctggacttc caagaccctg caatcctggc aacaggtatg
     1981 cagccggggg ttaaagagaa aaagccggag gaaaccagcc agtgtggtca ccagtgcagg
     2041 gatctacaaa aaagcccagc acccccaaaa acctcatctt gggaagtatg agcttcctgc
     2101 tcagccttca gcctgcgtgt gaaggctgct gactgcaaga acaggagagg caaagcccaa
     2161 atgggcagct tttcttcgtt ggctgattgt tggtaaatca aagtaaaaag tatatacaca
     2221 tatatgtgta tgcatgtgtg tatagatata cttacacaca catatatgga gtctaccttg
     2281 aatttcagaa ctacgtcata ggctgcaggt aaagggttct gttcagtttg ctgtctccct
     2341 gaagggtcgc tcattaagga aggagcctct cgtgtaactc atttgtggta aagtcgatga
     2401 ttcaaccacc ctctggaaaa cttttgttta ggcctcaaac acacgtgtgt gcattcagaa
     2461 gactgccgcc tgtgtacaaa cttgaggctg tgtgagctcc tttgccagcc aaagagcttc
     2521 ctttggacca gcaaatgaac caccccagtc tgctctccct ccctccccgc agctgtattg
     2581 agggggaggg agtgaggggg aggaggtaaa agaagggacc ctgagcccaa ggcctgcctg
     2641 caggtccctt ctttatagcc gtgtttctcc cgacacagaa cccaccctac cctcccatcc
     2701 cactgcaact ctaacacggg agaactcaaa tggtgtgcaa tactggtttg tttttttttt
     2761 tttttacatt cccccccctc cctatgaaaa caaatgagag gggggggggg aagtattctg
     2821 ttgtaaataa aaggcaacaa aagaaatcat ccaacaaaag aattaagagg cccaagcctc
     2881 aggggggaaa aaaaaccctt cagcctgata cattttgtgg ctttttaatg gaaaccaagc
     2941 cagtgtgttc tactcgtttg ggacttattt gtggagagga gaggggaggg ggggaaacca
     3001 gtggagagca ccagagggct tattgactct gaattgttaa acaaatgatt tccatgagtg
     3061 gtgttggagc acttgggaag acaaactttg tttccagcca gggagggcga tgcctgcctc
     3121 tgtatatctg taatatatga tatttttcat gctccactat tttattaaaa ataaaatagt
     3181 ttgctgctgc tagtca
//
