LOCUS       NP_001102646             820 aa            linear   ROD 29-JUL-2024
DEFINITION  FYN-binding protein 1 [Rattus norvegicus].
ACCESSION   NP_001102646 XP_001054436 XP_574859
VERSION     NP_001102646.1
DBSOURCE    REFSEQ: accession NM_001109176.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 820)
  AUTHORS   Menasche,G., Kliche,S., Chen,E.J., Stradal,T.E., Schraven,B. and
            Koretzky,G.
  TITLE     RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating
            T-cell-receptor-mediated integrin activation
  JOURNAL   Mol Cell Biol 27 (11), 4070-4081 (2007)
   PUBMED   17403904
REFERENCE   2  (residues 1 to 820)
  AUTHORS   Wu,J.N., Jordan,M.S., Silverman,M.A., Peterson,E.J. and
            Koretzky,G.A.
  TITLE     Differential requirement for adapter proteins Src homology 2
            domain-containing leukocyte phosphoprotein of 76 kDa and adhesion-
            and degranulation-promoting adapter protein in FcepsilonRI
            signaling and mast cell function
  JOURNAL   J Immunol 172 (11), 6768-6774 (2004)
   PUBMED   15153494
REFERENCE   3  (residues 1 to 820)
  AUTHORS   Fujii,Y., Wakahara,S., Nakao,T., Hara,T., Ohtake,H., Komurasaki,T.,
            Kitamura,K., Tatsuno,A., Fujiwara,N., Hozumi,N., Ra,C., Kitamura,D.
            and Goitsuka,R.
  TITLE     Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor
            complex in mast cells
  JOURNAL   FEBS Lett 540 (1-3), 111-116 (2003)
   PUBMED   12681493
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474048.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_574859.2, XP_001054436.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132291,
                              SAMD00132295 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..820
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q16"
     Protein         1..820
                     /product="FYN-binding protein 1"
                     /note="FYN binding protein (FYB-120/130); FYN-binding
                     protein; FYN-T-binding protein; SLP-76-associated
                     phosphoprotein; adhesion and degranulation promoting
                     adaptor protein"
                     /calculated_mol_wt=90206
     Region          <40..416
                     /region_name="PHA03247"
                     /note="large tegument protein UL36; Provisional"
                     /db_xref="CDD:223021"
     Region          489..592
                     /region_name="hSH3"
                     /note="Helically-extended SH3 domain; pfam14603"
                     /db_xref="CDD:464216"
     Region          732..820
                     /region_name="hSH3"
                     /note="Helically-extended SH3 domain; pfam14603"
                     /db_xref="CDD:464216"
     CDS             1..820
                     /gene="Fyb1"
                     /gene_synonym="ADAP; Fyb; p120/p130; RGD1563421; SLAP-130"
                     /coded_by="NM_001109176.1:103..2565"
                     /db_xref="GeneID:499537"
                     /db_xref="RGD:1563421"
ORIGIN      
        1 makfntgsnp teevstssrp fkvagqnsps giqskknlfd nqgnasppag psnmskfgtt
       61 kpplaakpty eeksekepkp pflkptgvsp rfgtqpnsvs rdpevkvgfl kpvspkptsl
      121 tkedskpvil rppgnklhnl nqesdlktlg pkpgstppvp endlkpgfsk iagakskfmp
      181 apqdadskpr fprhtygqkp slstedaqee esipkntpvq kgspvqlgak srgspfkpak
      241 edpedkdhgt psspfagvvl kpaasrgspg lsknseekke erktdipkni flnklnqeep
      301 arfpkapskl tagtpwgqsq ekegdkdsat pkqkplppls vlgpppskps rppnvdltrf
      361 rkadsanssn ksqtpystts lppppptqpa sqpplpashp ahlpapslpp rnikppldlk
      421 hpineenqdg vmhsdgtgnl eeeqesdgem yediessker dkkrekeekk rlelerkeqk
      481 erekkeqelr kkfkltgpiq vihhakaccd vkggknelsf kqgedieiir itdnpegkwl
      541 grtargsygy ikttavkidy dslkrkknti navpprpvee dqdvyddvae qdapnshsqs
      601 gsggmfpppp adddiydgie eedaddgsvp qvdektnaws wgilkmlkgk derkksirek
      661 pkvsesdsne gssfpsphkq ldvgeevydd vdasdfpppp aemsqgmsvg ktkaeekdpk
      721 klkkqekeek dlrkkfkydg eirvlystkv assltskkwg trdlqikpge sleviqstdd
      781 tkvlcrneeg kygyvlrsyl vdndgeiydd iadgciydnd
//
