LOCUS       NM_001004218            1630 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus alpha-L-fucosidase 2 (Fuca2), mRNA.
ACCESSION   NM_001004218 XM_214788
VERSION     NM_001004218.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Liu,T.W., Ho,C.W., Huang,H.H., Chang,S.M., Popat,S.D., Wang,Y.T.,
            Wu,M.S., Chen,Y.J. and Lin,C.H.
  TITLE     Role for alpha-L-fucosidase in the control of Helicobacter
            pylori-infected gastric cancer cells
  JOURNAL   Proc Natl Acad Sci U S A 106 (34), 14581-14586 (2009)
   PUBMED   19666478
REFERENCE   2  (bases 1 to 1630)
  AUTHORS   Sanchez-Bernal,C., Martin-Gonzalez,A., Cabezas,J.A., Villar,E. and
            Perez-Gonzalez,N.
  TITLE     Age-related excretion of six glycosidases in rat urine
  JOURNAL   Mech Ageing Dev 66 (2), 121-129 (1992)
   PUBMED   1365839
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078933.1.
            
            On Sep 10, 2004 this sequence version replaced XM_214788.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078933.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..1630
                     /gene="Fuca2"
                     /note="alpha-L-fucosidase 2"
                     /db_xref="GeneID:292485"
                     /db_xref="RGD:1303053"
     exon            1..289
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..1469
                     /gene="Fuca2"
                     /EC_number="3.2.1.51"
                     /note="plasma alpha-L-fucosidase; alpha-L-fucoside
                     fucohydrolase 2; fucosidase, alpha-L- 2, plasma"
                     /codon_start=1
                     /product="plasma alpha-L-fucosidase precursor"
                     /protein_id="NP_001004218.1"
                     /db_xref="GeneID:292485"
                     /db_xref="RGD:1303053"
                     /translation="MRLGLLMFLPLLLLATRYRAVTALSYDPTWESLDRRPLPAWFDQ
                     AKFGIFIHWGVFSVPSFGSEWFWWYWQKERRPKFVDFMDNNYPPGFKYEDFGVLFTAK
                     YFNANQWADLLQASGAKYVVLTSKHHEGFTLWGSAHSWNWNAVDEGPKRDIVKELEVA
                     VRNRTDLHFGLYYSLFEWFHPLFLEDQSSAFQKQRFPVAKTLPELYELVTKYQPEVLW
                     SDGDGGAPDHYWNSTDFLAWLYNESPVRDTVVTNDRWGAGSICKHGGYYTCSDRYNPG
                     HLLPHKWENCMTIDKFSWGYRREAEIGDYLTIEELVKQLVETVSCGGNLLMNIGPTLD
                     GIIPVIFEERLRQMGTWLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPEKKLVYAIFL
                     KWPISGKLFLGQPIGSLGETEVELLGHGRPLTWTSSKPSGIVVELPRLSVHQMPCKWG
                     WTLALTNVT"
     exon            290..477
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     exon            478..817
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     exon            818..1028
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1219
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1328
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1602
                     /gene="Fuca2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcgctagg cagcctctgc ggctgacaga aaaggtcccc ggctttccca gtgacttgcg
       61 gttccccgga ggaccccagg ctggcgcgca tgcgcctggg gctcctgatg tttctgccgc
      121 tactgctgct ggcaacccgg taccgggccg tgacagccct tagctatgac cccacgtggg
      181 agtctctgga cagacgcccg ctgccagcct ggttcgacca ggccaagttc ggcatcttca
      241 tccactgggg agtgttttcc gtgcccagct ttggtagtga atggttctgg tggtattggc
      301 aaaaggaaag gagacccaag tttgtggact ttatggacaa taattatccc cctggcttta
      361 agtatgaaga ttttggagtg ttatttacag ccaagtattt taacgcaaac caatgggcag
      421 atcttctcca ggcctctggt gccaaatatg tggtcttaac ttccaaacat catgaaggat
      481 tcactctgtg gggttcggcc cattcttgga attggaacgc ggtcgatgag gggccgaaga
      541 gggacatcgt caaggagctt gaggtggctg tgaggaacag gactgacttg cactttggtc
      601 tgtactattc tctttttgaa tggttccacc cactctttct ggaggatcaa tccagcgcgt
      661 tccagaagca gcggtttccc gttgctaaga cgttgcctga gctctatgag ttggtgacca
      721 agtaccagcc ggaagttctg tggtcagacg gagatggggg agcgccagat cactactgga
      781 atagtactga cttcttggcc tggctctata acgaaagccc agttcgggac acagtagtca
      841 ccaatgatcg ctggggagct ggctctatct gcaaacacgg tggttactat acttgcagtg
      901 accgttataa tcccggacat ctcttgccac acaagtggga gaactgcatg acaatagaca
      961 agttctcctg gggctacaga cgggaggctg aaatcggtga ctatcttacc attgaagaat
     1021 tggtgaagca acttgtggaa acggtctcat gtggaggaaa tctcctgatg aatattggcc
     1081 ccacactaga tggcatcatt cctgtaattt ttgaggagcg cttaaggcaa atgggaacct
     1141 ggctgaaagt caacggggaa gctatttatg aaacacatac ttggaggtct cagaacgaca
     1201 ccgtcactcc tgacgtgtgg tacacatcta aacctgagaa gaaattagtc tatgctattt
     1261 ttctgaaatg gcccatctct ggaaagctgt ttcttggaca acccataggt agtctggggg
     1321 aaacagaggt agaactactg ggccacggac ggccactgac ttggacatct tcaaagccaa
     1381 gcggcattgt ggtggagttg ccccggctaa gcgttcatca gatgccctgt aaatggggat
     1441 ggactctggc actaaccaat gtcacttaac ctgcagcaga cagatgcgtt ctacaggagc
     1501 ctctaaccac aggaaacgtc agggtttcct ttttttgttg ttgttgttgt tacactaaag
     1561 agactaaatg atataaaaat gatataaaaa ctgaagccat taaaaaaaaa aaaaaaaaaa
     1621 aaaaaaaaaa
//
