LOCUS       NM_001401166            1856 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus FtsJ RNA 2'-O-methyltransferase 1 (Ftsj1),
            transcript variant 2, mRNA.
ACCESSION   NM_001401166 XM_039100464
VERSION     NM_001401166.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1856)
  AUTHORS   Guy,M.P., Shaw,M., Weiner,C.L., Hobson,L., Stark,Z., Rose,K.,
            Kalscheuer,V.M., Gecz,J. and Phizicky,E.M.
  TITLE     Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in
            Nonsyndromic X-Linked Intellectual Disability due to Mutations in
            FTSJ1
  JOURNAL   Hum Mutat 36 (12), 1176-1187 (2015)
   PUBMED   26310293
REFERENCE   2  (bases 1 to 1856)
  AUTHORS   Guy,M.P. and Phizicky,E.M.
  TITLE     Conservation of an intricate circuit for crucial modifications of
            the tRNAPhe anticodon loop in eukaryotes
  JOURNAL   RNA 21 (1), 61-74 (2015)
   PUBMED   25404562
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000021.1.
            
            On Feb 3, 2022 this sequence version replaced XM_039100464.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399489.1364593.1,
                                           SRR26643294.62059.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-414               JAXUCZ010000021.1  16916033-16916446
            415-570             JAXUCZ010000021.1  16917075-16917230
            571-640             JAXUCZ010000021.1  16917475-16917544
            641-731             JAXUCZ010000021.1  16917631-16917721
            732-810             JAXUCZ010000021.1  16918891-16918969
            811-863             JAXUCZ010000021.1  16920769-16920821
            864-917             JAXUCZ010000021.1  16920910-16920963
            918-1020            JAXUCZ010000021.1  16921070-16921172
            1021-1104           JAXUCZ010000021.1  16921281-16921364
            1105-1202           JAXUCZ010000021.1  16921886-16921983
            1203-1391           JAXUCZ010000021.1  16922062-16922250
            1392-1433           JAXUCZ010000021.1  16922427-16922468
            1434-1856           JAXUCZ010000021.1  16923586-16924008
FEATURES             Location/Qualifiers
     source          1..1856
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..1856
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /note="FtsJ RNA 2'-O-methyltransferase 1"
                     /db_xref="GeneID:363450"
                     /db_xref="RGD:1561061"
     exon            1..414
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            415..570
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     CDS             450..1424
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /note="Ftsj homolog 1; putative tRNA
                     (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; FtsJ
                     RNA methyltransferase homolog 1"
                     /codon_start=1
                     /product="tRNA
                     (cytidine(32)/guanosine(34)-2'-O)-methyltransferase"
                     /protein_id="NP_001388095.1"
                     /db_xref="GeneID:363450"
                     /db_xref="RGD:1561061"
                     /translation="MGRTSKDKRDVYYRLAKEKGWRARSAFKLLQLDEEFQLFKGVKR
                     AVDLCAAPGSWSQVLSQKVGGQSSGQVVAVDLQAMAPLPGVIQIQGDITQLSTAKEII
                     QHFEGCPADLVVCDGAPDVTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRG
                     RDVTLLYSQLRIFFSSVLCAKPKSSRNSSIEAFAVCQGYDPPEGFIPDLTRPLMNHSY
                     DFNQLHGPARVIVPFVTCGDLSAYDSDRTYSLDLDNGSEYKYTPPTQPPIAPPYQEAC
                     RLKKNGQLAKEFLPQECSIDRVDKLSQPLAIHTLLAPKVEDNEINCSS"
     exon            571..640
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            641..731
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            732..810
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            811..863
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            864..917
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1020
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1104
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1202
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1391
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1433
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1856
                     /gene="Ftsj1"
                     /gene_synonym="RGD1561061"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcttacgtt gtgctctgat ctgaacctcc ttggaactca actatttcac aaagcaaact
       61 ttaccacgtt gtgacagcct ctaggcgtgt gcaataggcc ttcgggtcaa ctccgaacac
      121 caactatata gtcctacctt taaccatcag tttgcacact cttctttcag ccaccctctg
      181 tatccaagag gtgaggtagg tggtggggca ccgagaactt gaactgggac cgagactgaa
      241 ggcatgcctg ccctgtcccc aactcgggat aagggattca ctcggtgctg cagctgcgta
      301 gttcaatcaa gccctgggaa gcttgcccag agaactagaa tgctgggtga attcgagagg
      361 ggtacagcat ggagctacac aactgatctg ctatctactg ggccaccttg aagggacagc
      421 gtcagctccc tacctaccag caaactgaga tgggacggac atctaaggat aaacgggatg
      481 tctactaccg cctggccaag gagaagggct ggcgggcccg aagtgctttc aagctacttc
      541 aacttgatga ggaattccaa ctcttcaaag gtgtgaagcg agcagttgac ttgtgtgcag
      601 ccccaggcag ctggagccag gtgctgagcc aaaaggttgg gggccagagt tctggtcagg
      661 tggtggctgt ggacttgcag gctatggctc cactccccgg tgtgatacag atacagggtg
      721 acatcactca gctctccact gccaaggaga tcatccagca ctttgagggc tgccctgccg
      781 acctagtagt gtgtgacggg gctcctgatg tcactggcct ccatgatgta gatgagtaca
      841 tgcaggccca gcttctgctt gccgccctta acattgctac tcatgtcttg aagccagggg
      901 gctgctttgt ggccaagatc ttccgaggcc gggatgtgac gctgctctac agccaactac
      961 gcatcttctt ctccagtgtg ctgtgtgcta agcctaagag tagccggaac tccagcattg
     1021 aggcctttgc tgtgtgtcag ggttatgacc ctcctgaggg cttcattcca gatctgacca
     1081 gacccctgat gaaccactca tacgatttca accagctgca tggtcccgcc cgtgttattg
     1141 tgccctttgt gacctgtggg gacctcagcg cctacgattc ggaccgtact tactctctgg
     1201 atctagacaa tggctctgag tacaaatata ctccacccac acagcccccc attgcacctc
     1261 cataccagga ggcctgcagg ttaaagaaga atggacagct agccaaggaa ttcctccccc
     1321 aggaatgctc cattgacaga gtagacaagt tgtcccagcc tctggctatc cataccctgc
     1381 tagcccccaa ggtggaagac aatgaaatta attgttcatc ttaacacatt aagaatggct
     1441 cccgcaaaga agggtggcga gaagaagaag ggccgttctg ccatcaacga ggtggtgacc
     1501 cgagaataca ccatcagcat tcacaagcgc atccatggag tgagttcaag aagcgtgctc
     1561 ctcaggcact caaagaaatt cggaaatttg ccatgaagga gatggggact ccagatgtgc
     1621 gcatagacag caggctcaat aaagccgtct gggccaaagg aataaggaat gttccgtacc
     1681 accacatccg agtatgtttg tccagaaagt gtaatgagga taaggattca ccaaacaagc
     1741 tctacacact ggtaacttac atgcctgtta tcacattcaa aaatctacag acggtcaatg
     1801 tggatgagaa ctaactgctg aatgtcaaat aaagttacag aactgccaaa aaaaaa
//
