LOCUS       XM_039097564            1847 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus FTO, alpha-ketoglutarate dependent
            dioxygenase (Fto), transcript variant X1, mRNA.
ACCESSION   XM_039097564
VERSION     XM_039097564.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051354.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039097564.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1847
                     /gene="Fto"
                     /gene_synonym="RGD1305121"
                     /note="FTO, alpha-ketoglutarate dependent dioxygenase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 22 ESTs, 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 60 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:291905"
                     /db_xref="RGD:1305121"
     CDS             87..1592
                     /gene="Fto"
                     /gene_synonym="RGD1305121"
                     /codon_start=1
                     /product="alpha-ketoglutarate-dependent dioxygenase FTO
                     isoform X1"
                     /protein_id="XP_038953492.1"
                     /db_xref="GeneID:291905"
                     /db_xref="RGD:1305121"
                     /translation="MKRVQTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQL
                     KYPKLVFREAGSIPEELHKEVPEAFLTLHKHGCLFRDLVRIQGKDVLTPVSRILIGDP
                     GCTYKYLNTRLFTVPWPVKGCTINYTEAEIAAACQTFLKLNDYLQVETIQALEELAIK
                     EKANEDAVPLCMAEFPRAGVGPSCDDEVDLKSRAAYNVTLLNFMDPQKMPYLKEEPYF
                     GMGKMAVSWHHDENLVDRSAVAVYSYSCEGSEDESDDESSFEGRDPDTWHVGFKISWD
                     IETPGLTIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQR
                     CQLALQNVLNDSDNGDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYKICTDW
                     WCEPMTQLEGLWKKMESVTNAVLREVKREGLSVEQRSEILSAVLIPLTMRQNLRKEWH
                     ARCGKRHAPETGSLSSFRKKKNVIVRNEDVTHSSEPAFLFILCFPESYLLS"
ORIGIN      
        1 gtcgttgaaa gaactacaca caggaggcgg ggtccagggc gagggcggac acggcccacg
       61 gtggcgaagg cggctttaga agcagcatga agcgcgtcca gaccgcggag gaacgggagc
      121 gggaagctaa gaaactgagg ctcctcgagg agcttgaaga cacttggctt ccttacctga
      181 cccccaaaga tgacgagttc tatcagcagt ggcagctgaa atatcctaaa ctggttttcc
      241 gagaggctgg cagcataccc gaggagctgc acaaagaggt ccccgaggcc tttctcacac
      301 tgcacaagca tggctgcttg tttcgggacc tggtgaggat ccaaggcaaa gacgtgctca
      361 ccccggtgtc tcgcatcctc attggggacc ccggctgcac ctacaagtac ttgaacacca
      421 ggctcttcac cgtgccctgg ccagtgaagg gctgcaccat caattacaca gaggccgaga
      481 ttgccgccgc atgtcagacc ttcctcaagc tcaatgacta cctacaggtc gagaccatcc
      541 aggccttgga agaactggct atcaaagaga aggccaatga agacgctgtg ccgttgtgca
      601 tggcagagtt ccccagggct ggcgtgggac cgtcctgcga tgatgaagtg gaccttaaga
      661 gcagagcagc ctacaacgtg actttgctaa acttcatgga tcctcagaaa atgccgtact
      721 tgaaagagga gccctatttc ggcatgggga agatggcggt gagctggcac catgacgaga
      781 acttggtgga caggtcagcc gtggcggtgt acagctatag ctgtgaaggc tccgaggatg
      841 aaagcgatga cgagtccagc ttcgaaggca gagatcccga tacgtggcat gttggtttta
      901 agatctcatg ggacatcgag acgccaggct tgacaattcc tcttcaccag ggagactgct
      961 atttcatgct ggatgacctc aatgccaccc accagcactg tgttttggct ggctcacagc
     1021 ctcggtttag ctccacccac cgcgtggcag agtgctcaac aggcaccttg gattatatct
     1081 tacaacgctg ccagttggca ctgcagaatg ttctcaatga ctcggacaat ggcgacgtct
     1141 cgctgaagtc cttcgagcct gcagttctga aacaaggaga agagatccac aacgaggtcg
     1201 agtttgagtg gctgaggcag ttctggtttc aaggaaatcg atacaaaatt tgcactgatt
     1261 ggtggtgtga gcccatgact cagctggagg ggctgtggaa gaagatggag agtgtgacaa
     1321 atgccgtgct tcgtgaagtt aagagagagg ggctctccgt ggaacaaagg agtgaaattc
     1381 tgtctgccgt cctgatccca ctcaccatgc gccagaatct gaggaaagaa tggcacgcca
     1441 ggtgtggaaa aaggcacgcc cccgagacag gctctctcag ctctttcagg aagaagaaaa
     1501 atgtcattgt gcggaatgaa gacgtaacac attcatcaga gcccgccttc ctttttattt
     1561 tgtgcttccc tgaaagctat ctgctctcct aagcccgaga ccatcttctc cgcacaagtg
     1621 atatcttgat tgacacgtct ccaaataagc ttgtgaatag cttgccgtat taacctcgga
     1681 ataattcaga tgtcaaatta cagctcgcag actctctgac tcctcgcgga ggccccggaa
     1741 tgaatttttt ttaaatattt gggagaaaaa atattaaatt ttgttcaggt tgggtcaaag
     1801 ttcatatcat ttggtaataa agagccacag agggtgtttg cccagag
//
