LOCUS       NM_001170398           10769 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus FRY microtubule binding protein (Fry), mRNA.
ACCESSION   NM_001170398 XR_008372
VERSION     NM_001170398.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10769)
  AUTHORS   Nagai,T., Ikeda,M., Chiba,S., Kanno,S. and Mizuno,K.
  TITLE     Furry promotes acetylation of microtubules in the mitotic spindle
            by inhibition of SIRT2 tubulin deacetylase
  JOURNAL   J Cell Sci 126 (Pt 19), 4369-4380 (2013)
   PUBMED   23886946
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001170398.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU563850.1, EU563851.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-575               JAXUCZ010000012.1  9772817-9773391     c
            576-775             JAXUCZ010000012.1  9722687-9722886     c
            776-829             JAXUCZ010000012.1  9700633-9700686     c
            830-969             JAXUCZ010000012.1  9686121-9686260     c
            970-1060            JAXUCZ010000012.1  9681066-9681156     c
            1061-1140           JAXUCZ010000012.1  9680825-9680904     c
            1141-1221           JAXUCZ010000012.1  9680636-9680716     c
            1222-1390           JAXUCZ010000012.1  9671862-9672030     c
            1391-1483           JAXUCZ010000012.1  9667854-9667946     c
            1484-1582           JAXUCZ010000012.1  9667656-9667754     c
            1583-1684           JAXUCZ010000012.1  9665449-9665550     c
            1685-1788           JAXUCZ010000012.1  9660362-9660465     c
            1789-1897           JAXUCZ010000012.1  9659736-9659844     c
            1898-1984           JAXUCZ010000012.1  9657684-9657770     c
            1985-2156           JAXUCZ010000012.1  9652806-9652977     c
            2157-2289           JAXUCZ010000012.1  9650500-9650632     c
            2290-2397           JAXUCZ010000012.1  9649705-9649812     c
            2398-2653           JAXUCZ010000012.1  9641495-9641750     c
            2654-2836           JAXUCZ010000012.1  9638812-9638994     c
            2837-2923           JAXUCZ010000012.1  9637075-9637161     c
            2924-3183           JAXUCZ010000012.1  9633993-9634252     c
            3184-3373           JAXUCZ010000012.1  9632808-9632997     c
            3374-3498           JAXUCZ010000012.1  9632147-9632271     c
            3499-3556           JAXUCZ010000012.1  9629165-9629222     c
            3557-3648           JAXUCZ010000012.1  9628147-9628238     c
            3649-3821           JAXUCZ010000012.1  9627772-9627944     c
            3822-3982           JAXUCZ010000012.1  9625654-9625814     c
            3983-4093           JAXUCZ010000012.1  9624900-9625010     c
            4094-4248           JAXUCZ010000012.1  9623321-9623475     c
            4249-4348           JAXUCZ010000012.1  9622033-9622132     c
            4349-4520           JAXUCZ010000012.1  9621681-9621852     c
            4521-4777           JAXUCZ010000012.1  9615404-9615660     c
            4778-4924           JAXUCZ010000012.1  9614181-9614327     c
            4925-5093           JAXUCZ010000012.1  9612444-9612612     c
            5094-5184           JAXUCZ010000012.1  9610821-9610911     c
            5185-5267           JAXUCZ010000012.1  9606564-9606646     c
            5268-5418           JAXUCZ010000012.1  9602383-9602533     c
            5419-5522           JAXUCZ010000012.1  9601594-9601697     c
            5523-5708           JAXUCZ010000012.1  9600449-9600634     c
            5709-5907           JAXUCZ010000012.1  9598272-9598470     c
            5908-6029           JAXUCZ010000012.1  9596161-9596282     c
            6030-6217           JAXUCZ010000012.1  9594274-9594461     c
            6218-6312           JAXUCZ010000012.1  9593082-9593176     c
            6313-6920           JAXUCZ010000012.1  9589944-9590551     c
            6921-7018           JAXUCZ010000012.1  9588157-9588254     c
            7019-7189           JAXUCZ010000012.1  9586947-9587117     c
            7190-7330           JAXUCZ010000012.1  9581669-9581809     c
            7331-7510           JAXUCZ010000012.1  9578417-9578596     c
            7511-7672           JAXUCZ010000012.1  9575923-9576084     c
            7673-7747           JAXUCZ010000012.1  9572328-9572402     c
            7748-7918           JAXUCZ010000012.1  9568226-9568396     c
            7919-8116           JAXUCZ010000012.1  9559996-9560193     c
            8117-8278           JAXUCZ010000012.1  9559493-9559654     c
            8279-8445           JAXUCZ010000012.1  9556941-9557107     c
            8446-8635           JAXUCZ010000012.1  9555562-9555751     c
            8636-8785           JAXUCZ010000012.1  9550955-9551104     c
            8786-8884           JAXUCZ010000012.1  9549953-9550051     c
            8885-8968           JAXUCZ010000012.1  9547014-9547097     c
            8969-9079           JAXUCZ010000012.1  9537517-9537627     c
            9080-9282           JAXUCZ010000012.1  9532102-9532304     c
            9283-10769          JAXUCZ010000012.1  9530360-9531846     c
FEATURES             Location/Qualifiers
     source          1..10769
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p12"
     gene            1..10769
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /note="FRY microtubule binding protein"
                     /db_xref="GeneID:304244"
                     /db_xref="RGD:1307034"
     exon            1..575
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     CDS             506..9541
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /note="furry homolog"
                     /codon_start=1
                     /product="protein furry homolog"
                     /protein_id="NP_001163869.2"
                     /db_xref="GeneID:304244"
                     /db_xref="RGD:1307034"
                     /translation="MASQQDSGFFEISIKYLLKSWSNASPVGNGYIKPPVPPASGTHR
                     EKGPPAMLPINVDPDSKPGEYVLKSVFVSFTTQAERKIRIIMAEPLEKPLTKSLQRGE
                     DPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGMEDESHEYRPRTSNKSKSDEQQR
                     DYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDGLVHDIINLAFKHFKYKEGYLGPNT
                     GNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRQKEQSPYVVQSIISLIMGVKF
                     FRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAATVKNEVNV
                     PCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNL
                     KNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDM
                     PLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLRAFLVIADS
                     LQQKDGEPPMPVTGAVLPSGNTLRVKKTYLSKTLTEEEAKMIGMSLYYSQVRKAVGNI
                     LRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDGVSKVE
                     LIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREEVLFGFTNFLLREVNDVHHTLL
                     DSSLKLLLQLLTQWKLVIQTQGRVYEQAKIRNSELIPNGSGHRMQSERGPHCSVLHAV
                     EGFALVLLCSFQMATRKLSVLILKEIRALFLALGQPEDDDRPMIDVMDQLSSSILESF
                     IHVAVSDSATLPPTHNVDLQWLVEWNAVLVNSHYDVKSPSHVWIFAQSVKDPWVLCLF
                     SFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPNSPVNAKKTSTASSGDNYVTLW
                     RNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVSYDNKAIGTPSVGVLLKQLVP
                     LMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRL
                     QLLRIFELLADASVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKD
                     IRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDR
                     NHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEV
                     VMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVTLLNLVL
                     FKASDTNREIYEVSMQLMQILKAKLFLHSKKAAEQRPGSVLYGTHGPLPPLYSVSLAL
                     LSRELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGS
                     SPSSPEDEVKDREGEVTASHGLKGKGWGSPEATSLVLNNLMYMTAKYGDEVPGAEMEN
                     AWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVAIYLCRNNTIQTMEELL
                     FELQQTEPVNPIVQHCDNPPFYRFTASSKATAAASGTTSSSNTVVAGQDSFPDPEESK
                     ILKESDDRFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTGWLLSITEAKQPQPL
                     PMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLH
                     AVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEVKTLTMQPA
                     YQPEYLYTGGFDFLREDQSSPVPDSGLSSSSTSSSISLGGSSGNLPQMTQEVEDVDAA
                     AESDEKANKLIEFLTTRAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSKSG
                     LHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHG
                     DEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSSPDLSSSSKLTASRKSTGQL
                     NVSPGTPSGSTATAERSRHQRSFSVPKKFGVVDRSSDPPRSATLDRIQACTQQGLSSK
                     TRSSSSLKESLTDPSHVNHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAQMP
                     LEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSRVPMV
                     DSSQAIGFPLNVLCLLPQLIQHFENPNQFCKGIAERIAQVCLEEKNPKLSNLAHVMTL
                     YKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYCL
                     LSYMDLSVVPGKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLPSYQHSDL
                     SKIELHRVWTSASKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPRAMAVTRS
                     ASSTSSGSNSNVLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGD
                     LDLPEHQTSLVSSEDGTREQENMDDANSEQQFRVFRDFDFLDVELEDGEGESMDNFNW
                     GVRRRSLDSLDKCDMQTLEERQLSRSTPSLNKMSHEDSDESSEEDLTASQILEHSDLI
                     MNLSPSEEANPMELLTSACDSTPADPHPFNARITNFEASLPDINNLQISEGSKAEVVP
                     EEEDTTVHEDDLSSSINELPATFECSDSFSLDMTEAEEKGNRGLDQYTLASFGEGDRG
                     VSPPPSPFFSAILAAFQPVSCDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNI
                     QKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKL
                     KFSVLELQEYLDTYNNRKEATLSWLANCKATFAGSSRDEVITCQPGDSEEKQLELCQR
                     LYKLHFQLLLLYQSYCKLIGQVHEVSSVPELLNMSRELSDLKRKLKEATAAISTDPLY
                     IEGAWSEPTFTSTEAAIQSMLECLKNNDLGKALRQIKECRSLWPNDIFGSSSDDEVQT
                     LLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIRRAQSSRVLTTFLP
                     DSSVSGTSL"
     exon            576..775
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            776..829
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            830..969
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1060
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1140
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1221
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1390
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..1483
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1484..1582
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1583..1684
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1685..1788
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1897
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..1984
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2156
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2289
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2397
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2398..2653
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..2836
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2837..2923
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3183
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3184..3373
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3374..3498
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3499..3556
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3557..3648
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3649..3821
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3822..3982
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            3983..4093
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4094..4248
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4249..4348
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4349..4520
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4521..4777
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4778..4924
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            4925..5093
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5094..5184
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5185..5267
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5268..5418
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5419..5522
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5523..5708
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5709..5907
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            5908..6029
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            6030..6217
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            6218..6312
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            6313..6920
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            6921..7018
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7019..7189
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7190..7330
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7331..7510
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7511..7672
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7673..7747
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7748..7918
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            7919..8116
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8117..8278
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8279..8445
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8446..8635
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8636..8785
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8786..8884
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8885..8968
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            8969..9079
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            9080..9282
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
     exon            9283..10769
                     /gene="Fry"
                     /gene_synonym="RGD1307034"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtggaggct gggtgggagc tcaggttgag aaaggcaggg actgggggcg gggcttcagg
       61 ccatccctca gtagggggct gcagggtggg cagccaggag gcccagacat ccgtccaccc
      121 cggggcagca gctcacggtg caggtgggga ctcggctacc atacctggct gtggctgagt
      181 atgtgggcgg ccgcaggcag taggcaggca ttgctgctta tgtcagctct gaaatgaaag
      241 cagctgaggc ctctgcctct gaaggcttgc aagggagatc agcacccagc aaataagaag
      301 ccagccctgg ccccggagga ggaggaggag gaggaggagg agaggttaag catccctctc
      361 ccggtgtcct ttaaatgtgg agcgtggccg tctgcttctg accctcgctt acatcactaa
      421 cctgtgacca gcgcatctcc acgcccggta cctgctcctc caacagcagc ttccagtcct
      481 aggagcctct ttgtatgcgg cagacatggc cagccagcag gattccggct tctttgaaat
      541 cagtatcaaa tatttactga aatcctggag taacgcttct ccagttggca acggttacat
      601 caagcctcca gtcccacctg cttcaggcac gcacagggag aaaggaccac cggccatgtt
      661 gccgatcaat gtggacccag acagcaagcc aggagagtat gtcctcaaga gtgtatttgt
      721 gagcttcacc actcaggctg agcgtaagat tcgaatcatc atggcagagc ctttggaaaa
      781 gccattgaca aaatccctgc agcgtggaga agacccccag ttcgaccagg tcatcagctc
      841 catgagttcc ctctctgagt actgcctgcc ctccatcctg cgaacactgt ttgactggta
      901 caaaaggcag aacggcatgg aggacgaatc gcacgagtac agaccacgaa cgagcaataa
      961 gtccaaaagt gacgagcagc agcgagacta tttgatggag agacgggacc tcgccatcga
     1021 ctttatcttc tctttagtgt taatagaggt cttgaagcag atcccccttc atcctgtaat
     1081 agacggctta gtacacgata ttattaactt ggctttcaag cactttaagt acaaagaagg
     1141 gtacctgggt cccaacaccg gcaacatgca cattgtagca gatctgtacg cagaggtcat
     1201 cggagtgctg gcccaagcca agttccctgc tgtcaagaag aagttcatgg cagagctgaa
     1261 ggagctacgg cagaaagagc agagccccta tgtggtgcaa agtatcatca gcttaataat
     1321 gggggtaaaa ttcttccgaa ttaagatgta cccagtggag gacttcgagg cgtccctcca
     1381 gttcatgcag gaatgtgcac attattttct ggaggtcaaa gacaaagaca tcaagcacgc
     1441 cttagcaggg ctctttgtag aaatcctcgt ccccgtggct gccactgtca aaaatgaagt
     1501 caacgtcccc tgcctcagga actttgtgga gagcctgtac gacacaacgt tggaactctc
     1561 ctctcggaaa aagcattcct tggccttata cccgctggtg acctgcctcc tctgtgtcag
     1621 tcagaagcag ctgttcctta acagatggca cgttttcctc aacaactgcc tgtccaacct
     1681 taagaataaa gaccccaaga tggctcgcgt cgccttggag tctctctaca gattactgtg
     1741 ggtttacatg attcgaatca aatgtgaaag caacacggcc actcagagcc gactcataac
     1801 catcaccacc acgcttttcc ccaaagggtc ccgcggcgtg gtgcccaggg atatgcctct
     1861 gaacatcttc gtgaagatta tccagttcat cgcccaggaa cgtctggact ttgcaatgaa
     1921 ggaaattatt tttgactttc tttgtgtggg aaaaccggcg aaagctttca gtctcaaccc
     1981 agagagaatg aacattggtt tgcgggcgtt cctggtgatt gccgatagct tacaacaaaa
     2041 ggacggtgag cctcccatgc cggtgactgg agccgtgctc ccttcaggaa acaccctgag
     2101 agtgaagaaa acgtatttga gtaagacact aactgaagag gaagccaaaa tgataggaat
     2161 gtccttgtat tactctcaag tccgcaaggc ggtaggcaac atcttaagac accttgataa
     2221 agaagtgggg cggtgcatga tgctgaccaa tgtccagatg ctaaacaaag agccggaaga
     2281 catgatcacg ggtgagagaa agcccaaaat cgatctcttc cggacctgtg ttgcggcaat
     2341 ccctcgcctg ctacctgatg gagtgtccaa agttgaactg atcgacttgc tggccaggct
     2401 ctccattcac atggacgatg aactgcgtca catcgcacag aactctcttc agggactgct
     2461 ggtcgacttc tccgactgga gggaagaagt cctgttcggc ttcaccaact tcctgctccg
     2521 ggaagtcaat gatgtgcatc acaccctcct ggactcctcc ctgaagttgc ttctgcaatt
     2581 gctcacccag tggaaactgg tcatacagac acagggaaga gtctatgaac aggccaagat
     2641 cagaaactca gagctcattc ccaacggctc cggccacagg atgcagtcag aacgaggccc
     2701 gcactgcagt gtcctccacg ccgtggaagg cttcgccctc gtcttgctct gcagcttcca
     2761 gatggccaca cgcaaactgt ccgtgttgat cctcaaggag attcgagccc tcttccttgc
     2821 cctgggtcag cccgaggacg atgacaggcc aatgattgat gtcatggatc agctgagttc
     2881 ttccattctt gaaagtttca ttcatgtggc tgtgtcggat tcggcaacgt tacctccgac
     2941 ccacaatgtg gacctccagt ggctggtgga gtggaacgcg gtcctggtca acagccacta
     3001 cgacgtgaag agcccttccc acgtctggat cttcgcgcag tctgtcaaag acccctgggt
     3061 cctctgcctc ttcagcttcc tccggcagga aaacctgcca aagcactgcc ccacagccct
     3121 cagctatgcc tggccgtacg ccttcacccg gctgcagtcc gtgatgccgc tggtagatcc
     3181 taacagccca gtcaacgcca agaaaaccag cacagcaagc agtggagaca actatgttac
     3241 cttgtggaga aattacctca ttctctgttt tggagttgcc aaacccagta ttatgagccc
     3301 aggacacctt cgagcatcca ctccagagat aatggcaaca actcccgatg gtacagtgag
     3361 ctacgataac aaggccattg gcacgccgtc agtgggcgtc ctgctgaagc agttggtgcc
     3421 tttgatgagg ctggagagca tcgaaatcac agagtccctt gttttagggt tcggaaggac
     3481 aaattccctt gttttcagag aattggttga agaactccat ccattaatga aggaggctct
     3541 agagaggaga ccagagaaca agaagcgccg agaacggaga gatttgctga ggctgcagct
     3601 gcttcggata ttcgagctcc tggcagacgc tagtgtgata agtgacagca caaatggagc
     3661 tttagaacga gacaccttag cgcttggagc gttgttcttg gaatacgtgg acttgacccg
     3721 catgctccta gaagctgaaa atgacaaaga agtcgaaatc cttaaagaca ttcgagcaca
     3781 ttttagcgcc atggttgcca acttgattca gtgtgttcca gttcaccaca gaagatttct
     3841 cttcccccag caaagcctgc ggcaccatct cttcatcttg ttcagccagt gggccggccc
     3901 cttcagtatc atgtttaccc ctctggatcg gtacagtgac cgaaaccacc agatcacaag
     3961 ataccagtac tgtgctctga aggcaatgtc agcggtgctg tgctgcggcc ctgttttcga
     4021 caatgtcggc ctctctccgg atggctatct gtataagtgg cttgacaata ttctggcttg
     4081 tcaagattta cgggttcatc agcttggctg tgaggtcgtc atgttgctac tggagcttaa
     4141 tcctgaccaa ataaaccttt tcaattgggc catcgaccgc tgttacacag gttcctacca
     4201 gcttgcttcc ggctgcttca aagccattgc aaccgtgtgc ggaaacagga actacccctt
     4261 cgacatagtg acactgctga acctcgtcct cttcaaggcc tcggacacca acagagagat
     4321 ttacgaagtc tccatgcagc tcatgcagat cctcaaagcg aagctcttcc tgcactccaa
     4381 gaaggccgca gaacagcgac cgggcagtgt tctgtatgga acgcacgggc cattgccgcc
     4441 tctctacagt gtgtcgctag ccctgctgtc ccgagaactg gcccggatgt acccggagct
     4501 cacacttccc ctcttctcag aggtgagcca gcgattcccc acgacacacc caaatggacg
     4561 gcagatcatg ctcacctacc tgttgccatg gctacacaat attgaactgg tggacagcag
     4621 actcctcctc ccgggctcaa gtcccagcag ccccgaggat gaagtcaagg accgggaagg
     4681 agaagtgact gcctctcacg ggctaaaagg gaagggctgg ggctctccgg aagccacctc
     4741 tctggtcctg aataacctca tgtacatgac agccaagtac ggagatgaag tcccaggagc
     4801 agaaatggaa aatgcttgga acgcactggc caacaacgag aaatggagta acaacctgag
     4861 ggtcacactg cagttcctca tcagcctgtg cggggtcagc agcgacacca tccttctgcc
     4921 ctacattaaa aaggtggcaa tttacttgtg tcggaataat accatccaga ccatggaaga
     4981 gctcctcttc gagctgcagc agacagagcc ggtgaacccc attgtccagc actgtgacaa
     5041 cccacccttc tatcggttca cagccagcag caaagccaca gcggctgctt caggaaccac
     5101 ttcgagcagt aacactgtgg ttgccggcca ggacagcttc ccagaccctg aggagagcaa
     5161 gatactgaaa gaatctgatg acaggtttag caacgtgatc cgagcccaca ctcgcctaga
     5221 gtcaagatac agcaacagct ccggagggtc ttatgatgag gataaaaatg atcccatctc
     5281 tccctacacg ggctggttgt taagtattac ggaggccaag cagccacagc ctttacccat
     5341 gccgtgcact ggaggatgct gggcaccctt ggtcgactac ctcccagaga ccatcactcc
     5401 gcggggcccg ctgcacaggt gtaacattgc tgtgattttt atgaccgaga tggtggtgga
     5461 tcacagtgtg agagaagact gggctcttca cctcccactg ttacttcatg ctgtcttctt
     5521 aggtttggac cattatcggc cggaagtctt cgagcacagc aaaaagctgc tccttcacct
     5581 cctcatcgca ctctcttgta atagcaactt ccacgccatt gcctccgtac tcctgcagac
     5641 ccgtgagatg ggggaagtga agacgctgac catgcagcca gcctaccagc cagagtatct
     5701 ctacacgggt ggctttgact tcctgagaga ggatcagtcg tcgccagtgc ccgactccgg
     5761 cctgagctca agctccactt cctccagcat cagtctgggg ggcagcagtg ggaacctccc
     5821 acagatgacc caggaggtgg aagatgtcga cgcggccgct gagtcggacg agaaggccaa
     5881 caagctcatt gagtttctga ccaccagggc attcgggcca ctttggtgcc acgaggacat
     5941 cacacccaaa aaccagaact ccaagagcgc tgagcagctt tctaatttcc tacgtcacgt
     6001 tgtgtctgta tttaaggatt ccaagtcagg tctccatctg gagcagcacc tgagcgaggt
     6061 tgccctgcag actgccctcg caagctcttc caggcactac gcaggccgat ctttccagat
     6121 cttccgggcc ctcaaacaac ccctgtcggc gcatgccctg tctgacctcc tgtccagatt
     6181 ggtggaggtg atcggagagc atggtgatga gattcaggga tacgtgatgg aagcactctt
     6241 gaccttggaa gccgcagtgg acaacttgtc ggattgcttg aagaacagtg acctcttcac
     6301 agtgttatct cgttcttcct caccagatct aagctctagc agtaaactga cagcaagcag
     6361 gaaaagtacc ggacagctga acgtcagccc cgggactccc agcggcagca ccgcgaccgc
     6421 agagcgcagc cggcaccaaa gaagcttctc cgtgcccaag aagtttggtg tcgttgaccg
     6481 atcctcggac ccgcctcgaa gcgctaccct ggataggatt caggcttgca ctcagcaagg
     6541 cctttcctca aaaaccagaa gcagctcctc cctgaaggag agcctcacag acccttccca
     6601 cgtaaaccat cccaccaacc tgctggccac catcttctgg gtcacggtgg ccctgatgga
     6661 gtctgacttt gagtttgaat acctgatggc cttgaggctc ctgaaccgac tgctggcaca
     6721 gatgccactg gagaaagccg agaaccgaga gaagctcgag aaactccagg cgcagctcaa
     6781 gtgggcagac ttcccggggc tgcagcagct gctgctgaag ggcttcacct ctctcaccac
     6841 cacggacctg accctgcagc ttttcagctt gctgacacca gtgtccagag tgcccatggt
     6901 ggactcgtcc caagctatcg gatttccgct gaatgtcctg tgtctcctgc ctcagctgat
     6961 ccagcatttt gaaaatccca atcagttctg taagggcatc gccgaaagga ttgctcaggt
     7021 ttgcttggaa gaaaagaatc ctaaactttc aaatctggcc cacgtcatga ccctttacaa
     7081 aacacacagc tacacaaggg actgcgccac gtgggtcaac gtcgtctgcc gctaccttca
     7141 cgaagcctat gctgacatca ccctgaacat ggtcacctac ctggcagagt tgttggagaa
     7201 aggccttccc agcatgcaac agccactcct ccaggtcatc tactgtctgc tgagctacat
     7261 ggacctctct gtagttcctg gcaagcagtt taacatggaa gtcctgaaga ccattgagaa
     7321 atacgtacag agcattcact ggagggaagc gttgaacatc ttgaagctgg tcgtttctcg
     7381 gtcagccagc ctggtattgc cttcctacca gcacagtgac ctctccaaga tagaactcca
     7441 ccgggtgtgg accagcgcct cgaaggaact gccgggcaag accctggatt tccactttga
     7501 catctcagag actccgatca ttgggagacg gtatgatgaa ctccagaatt cctccggacg
     7561 ggatgggaaa cctagggcca tggctgtcac ccggagtgca tcctccacct cctcaggctc
     7621 taactccaat gtccttgttc ctgtgagctg gaaaagaccc cagtattctc agaaaagaac
     7681 aaaagagaag ctggtgcacg tcctctctct gtgcggccag gaagtcggac taagcaaaaa
     7741 cccgtctgtg attttttcct cgtgtggaga cctggatctg ccggagcatc agacgagcct
     7801 ggtgtcgtcc gaggacggca cccgggagca ggagaacatg gatgacgcca acagcgagca
     7861 gcagttcaga gtcttcaggg acttcgactt cctggacgtg gaactggagg acggggaggg
     7921 ggagagtatg gacaacttca actggggagt gcgcaggcgc tccctggaca gcctggacaa
     7981 gtgcgacatg cagaccctgg aggagcgcca gctctctaga agcactccca gcctaaacaa
     8041 gatgagccac gaggattcag atgagtcatc ggaggaggac ctcaccgcca gccagatcct
     8101 ggaacattca gaccttatca tgaatctctc cccctccgag gaggccaatc ctatggagct
     8161 gctgaccagc gcctgtgact ccaccccggc agaccctcat cccttcaatg ccaggataac
     8221 aaacttcgag gcctctttgc ctgatatcaa taatctgcag atttcggagg ggtcaaaggc
     8281 tgaggtagtc ccggaagagg aagacaccac cgtgcatgaa gacgatcttt caagctccat
     8341 caatgagctc ccagcaacgt ttgaatgcag tgacagcttc agcctggata tgacggaggc
     8401 ggaggaaaaa ggcaatcggg gcctggacca gtacactctc gccagctttg gagaaggtga
     8461 cagaggcgtg tctccccctc cctcgccctt cttctcggcc atccttgcgg ccttccagcc
     8521 ggtctcctgt gatgacgctg aggaagcctg gcgcagccac attaaccagc tcatgtgtga
     8581 ctcagacggc tcctgtgctg tgtacacatt tcatgtgttc tcctctctgt ttaagaatat
     8641 tcaaaagagg ttctgcttcc taacctgtga tgcagccagt taccttggcg ataacctccg
     8701 gggaatcggg tccaaatttg tcagctcttc ccagatgctt acctcctgct ctgagtgccc
     8761 tacactgttc gtggacgcag agactctcct ttcctgtggg ctcctggaca agctgaagtt
     8821 cagcgtgttg gaactgcaag agtatttgga cacatacaac aacaggaagg aggccacgct
     8881 ctcgtggctt gccaactgta aggcaacatt tgcaggcagc tccagggatg aggtgattac
     8941 ctgccagccc ggggactcgg aagaaaagca actggagctg tgtcagagac tgtacaagct
     9001 gcactttcag ctgctcctgc tctaccaatc ctactgcaag ctcattggcc aggtgcacga
     9061 agtgagctca gtgcccgagc tgctgaacat gtccagagaa ctgagtgatc tgaagaggaa
     9121 gctgaaagaa gccactgcag ccatctccac ggacccactg tacatcgagg gggcgtggtc
     9181 agaaccaacc ttcacatcca ctgaggcagc catccagtcc atgctggagt gcctgaagaa
     9241 caatgacctt ggcaaagcac tgcgacagat caaggagtgc agaagcctgt ggcccaatga
     9301 catctttgga agcagctctg atgatgaggt ccagacactc ctgaatattt atttccgtca
     9361 ccaaacattg ggacagacgg gtacttatgc cctggtgggg tctaaccata gcctgactga
     9421 aatctgcacc aagctcatgg agctgaacat ggagatccga gacatgatcc gcagggccca
     9481 gagctcccgg gtcctcacaa cctttctccc agactccagt gtttccggca ctagtctctg
     9541 acaggaggct cctgtccccc atggtttcta agcttgcaat gctgccatgc tggggcgacg
     9601 tcattcaatg tcttctcggc cttcgcaaag cttggacaga gcattctcct cttgttccct
     9661 gtaggacttt ttctaaagaa gatgactcaa cttccaatgt gcacaatact ctccaaacca
     9721 aggcagccta ggatctgctg acacagactc tacccatcct gatgtgtggc tactattcac
     9781 caagcaaagg caaccaacta cgggaggcag gacttccatt gctttaccaa agctgagcac
     9841 actgaacgac cccatccttt ctagagacac tttaggattg gcagaagtgc aatgtttttc
     9901 ttcacaggaa agcaaatttt tattctgaac gttgtacatt cattcccttc cttccaccta
     9961 ttttgcttcc tttgaatttc ctttctttct ttctttttgt gtggaatgtg tttctttgtt
    10021 tctttgagtt gcaaaagggg gcaggcagaa tgaagctggc cacggaaaac ctgtaagatg
    10081 gtcaaaagct gacagcctgt gtgcctgaaa agggaattgt aaatgagtta caatttgatg
    10141 tacactgtat ctaaatgagg ctgctatgaa gtaattttct taagttgcta ggctgccgtt
    10201 tctgaaaacc ctggatctct ctgtgccagg aaagatcccg atggaatcat tttcaggatc
    10261 atggctgctt tttacacaca ggttgcttta ataggcatcg gttataccac agaagacgag
    10321 tgtctgtttg cattaccttt accatcttgt agaaaagcaa gttattcaca aaaaccacaa
    10381 ttcgttttat ctgtctgcat gcattcttta gtagctattt ggagagccac aagtagagtc
    10441 atacatcaaa gatctaagtt gccacttaaa aaagatgtcc tattttattt gtaatatatg
    10501 tgtaaagtgt ctttcttaaa agctccttcc ttaaacccag cactgtggag tgttagatgt
    10561 gggcatgtga tctgttgctc atccaaaaca tattcagact tggtctatgt aacttattca
    10621 ctgtgtaaat acatttaaag tttttgtgat gtgaccttgg ttgataattc tgttcagaat
    10681 tgcctttaga ttacaaaaga gaaaaaaaag acaagagaca tgttgatcat ggattttatt
    10741 tctagtcaaa ttaaaatatt tgcctttga
//
