LOCUS       NM_001017382            2173 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus fibroblast growth factor receptor substrate 3
            (Frs3), mRNA.
ACCESSION   NM_001017382 XM_006244436 XM_236921
VERSION     NM_001017382.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2173)
  AUTHORS   Grossmann,A., Benlasfer,N., Birth,P., Hegele,A., Wachsmuth,F.,
            Apelt,L. and Stelzl,U.
  TITLE     Phospho-tyrosine dependent protein-protein interaction network
  JOURNAL   Mol Syst Biol 11 (3), 794 (2015)
   PUBMED   25814554
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2173)
  AUTHORS   Cotton,L., Gibbs,G.M., Sanchez-Partida,L.G., Morrison,J.R., de
            Kretser,D.M. and O'Bryan,M.K.
  TITLE     FGFR-1 [corrected] signaling is involved in spermiogenesis and
            sperm capacitation
  JOURNAL   J Cell Sci 119 (Pt 1), 75-84 (2006)
   PUBMED   16352663
  REMARK    Erratum:[J Cell Sci. 2006 Feb 1;119(Pt 3):604]
REFERENCE   3  (bases 1 to 2173)
  AUTHORS   Xu,H., Lee,K.W. and Goldfarb,M.
  TITLE     Novel recognition motif on fibroblast growth factor receptor
            mediates direct association and activation of SNT adapter proteins
  JOURNAL   J Biol Chem 273 (29), 17987-17990 (1998)
   PUBMED   9660748
REFERENCE   4  (bases 1 to 2173)
  AUTHORS   York,R.D., Yao,H., Dillon,T., Ellig,C.L., Eckert,S.P.,
            McCleskey,E.W. and Stork,P.J.
  TITLE     Rap1 mediates sustained MAP kinase activation induced by nerve
            growth factor
  JOURNAL   Nature 392 (6676), 622-626 (1998)
   PUBMED   9560161
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Dec 7, 2020 this sequence version replaced
            XM_006244436.3, NM_001017382.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.47768.1,
                                           SRR26643429.33024.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                JAXUCZ010000009.1  20794729-20794822   c
            95-237              JAXUCZ010000009.1  20792874-20793016   c
            238-326             JAXUCZ010000009.1  20791574-20791662   c
            327-513             JAXUCZ010000009.1  20790609-20790795   c
            514-675             JAXUCZ010000009.1  20788625-20788786   c
            676-830             JAXUCZ010000009.1  20787658-20787812   c
            831-2173            JAXUCZ010000009.1  20786096-20787438   c
FEATURES             Location/Qualifiers
     source          1..2173
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..2173
                     /gene="Frs3"
                     /note="fibroblast growth factor receptor substrate 3"
                     /db_xref="GeneID:316213"
                     /db_xref="RGD:1310226"
     exon            1..94
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     exon            95..237
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     exon            238..326
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1742
                     /gene="Frs3"
                     /note="SNT-2; FGFR substrate 3; FGFR-signaling adaptor
                     SNT2; suc1-associated neurotrophic factor target 2"
                     /codon_start=1
                     /product="fibroblast growth factor receptor substrate 3"
                     /protein_id="NP_001017382.2"
                     /db_xref="GeneID:316213"
                     /db_xref="RGD:1310226"
                     /translation="MGSCCSCLDRDSVPHNHPTKFKVTNVDDEGVELGSGVMELTQSE
                     LVLHLHQQEAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQ
                     DLMQCNSINVTEEPVIITRNSHPQELDLPRGSSQPTGYTVSSFSNGFPGCPGEGPRFS
                     SAPRRPSTSSLRHPSPGEESTQTLIASDEQSHTYVNTPTGEEDRRSRHCLQPLPEGRV
                     PFPPQTQVSDQRDPQVFLQPGQVKFVLGPTPARRQVMKCQSLCPSMQDPPLHNNNNEG
                     PSECPAQPKCTYENVSGGLQQGAGWRLSPEERGWSGLAHRRAALLHYENLPPLPPVWE
                     SQVQQLGGEAGDDGDSKDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSSFPVPLT
                     RRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKGWGTAHPKGPQNPSVSGAPGPTPHPA
                     RSSDSYAVIDLKKTVAMSNLQRALPRDDGTVRKTRHNSTDLPL"
     exon            327..513
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     exon            514..675
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     exon            676..830
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
     exon            831..2173
                     /gene="Frs3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcggggct gggaggcctt agctgcgggc gggcggcggc tgctgcagcg ggacccggga
       61 gcggggcccg gcgccgcccg ggccgcgggg cgatgtgagc cccaggtgtg acccccaggg
      121 atccaggtga agtctctgca gacactctgc catgacaccc caccaagaac aaggggaata
      181 aagtgggacc ctttcccatg cccctcccac ggtcagcacc ccgatggcct gggtgagggc
      241 tgataggctg ctctgacacc atggggagct gctgtagctg cctggacaga gacagcgtgc
      301 cacacaacca ccctaccaag ttcaaggtga caaatgtgga tgatgaaggg gtggagttgg
      361 gctcaggggt gatggagctg acccagagcg agctggtgct gcacctgcac cagcaggaag
      421 ctgtccgctg gccctacctc tgcctgcggc gctatggcta cgactccaat ctcttctcct
      481 ttgagagtgg ccgccgctgt cagacaggcc aggggatctt tgcgttcaag tgctcaaggg
      541 cagaggaaat cttcaacctg ctgcaggacc tcatgcagtg taacagcatc aatgtgacag
      601 aagagccggt catcatcaca cggaacagcc acccacaaga gcttgacctc cctcgaggct
      661 cctcccagcc cacgggctac acagtctcca gcttctccaa tggcttccct ggctgccctg
      721 gagaaggccc acggttctcc tctgctccgc gccgaccctc cacaagcagt ctgcgacacc
      781 cgtcgcctgg ggaagagtcc acccagaccc tcattgcctc ggatgagcag tctcacacct
      841 atgtcaacac accaaccggg gaagaggacc gcaggagtcg ccactgcctg cagccactgc
      901 ctgagggcag agtgcccttc ccaccacaga cacaggtctc cgaccagcgg gacccacagg
      961 tgttcctgca gccagggcag gtcaagttcg tgttgggccc cacgcctgct cgacgacagg
     1021 tgatgaagtg ccagagcctc tgccccagca tgcaggaccc tcccctccac aacaacaaca
     1081 acgagggccc ttccgagtgc ccagcccagc ccaaatgcac ctatgagaat gtcagtggag
     1141 gtctgcagca aggggctggc tggagactga gcccagagga gcgagggtgg agtggcctgg
     1201 cccaccgtcg ggctgccctg ctgcactatg aaaacctgcc ccctcttcct cctgtgtggg
     1261 agagccaagt ccaacagctg ggaggggagg ctggggatga tggggactcc aaggatgggc
     1321 ttaccccgtc ctcaaatggc ttccctgatg gtgaggaaga tgaaaccccg ctacagaagc
     1381 ccaccagcac ccgagcctcc gcccgtagtc acagcagctt cccggtccct ctgacccgcc
     1441 gccgaggctc cccaagggtc ttcaactttg atttccgccg gccgggccct gagcccccaa
     1501 ggcagctcaa ctacatccag gtggagctca agggctgggg cacagcccat cccaaggggc
     1561 cccagaaccc ctcggtatct ggagctcctg ggcccacccc acaccctgct cgaagctcag
     1621 actcctatgc cgtgattgac ctcaagaaaa cggtggccat gtccaacctg cagagggctc
     1681 tgccccgaga tgacggcact gtcaggaaga ctcggcacaa cagcaccgac ctgcctctgt
     1741 agacctggtc ctccacctgc ctctgcctgc agcgggcaga ctccacctca cccaccagcc
     1801 caggacacac agctgctttg cagaagacac taccctgcac tgctggggtc cccaaagatg
     1861 tcagccaccg agtgtctggg gagagggggg agaagagggg gagcaggaga ggatggagcc
     1921 acggtgtaaa ctgtgaaggg ttctcaaggt tgcatttcgc acccttccct aatgtctgtc
     1981 tgtctagtct gtcagctgtc cgtgtgtctg tgctttctgt ttccttttcc tttccttttt
     2041 tttttttttc tttttggttg gagttttgag acattttgta cctgttggtt ttatttatca
     2101 gtttattttt ctatttattg ttttaaatgt aacttaacat atttattatt aatataatta
     2161 tttttaaatt ctg
//
