LOCUS       NM_001107937            4921 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus FERM and PDZ domain containing 1 (Frmpd1), mRNA.
ACCESSION   NM_001107937 XM_001071316 XM_017593725 XM_017603000 XM_233002
VERSION     NM_001107937.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4921)
  AUTHORS   Yuzawa,S., Kamakura,S., Iwakiri,Y., Hayase,J. and Sumimoto,H.
  TITLE     Structural basis for interaction between the conserved cell
            polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched
            protein (LGN)
  JOURNAL   Proc Natl Acad Sci U S A 108 (48), 19210-19215 (2011)
   PUBMED   22074847
REFERENCE   2  (bases 1 to 4921)
  AUTHORS   An,N., Blumer,J.B., Bernard,M.L. and Lanier,S.M.
  TITLE     The PDZ and band 4.1 containing protein Frmpd1 regulates the
            subcellular location of activator of G-protein signaling 3 and its
            interaction with G-proteins
  JOURNAL   J Biol Chem 283 (36), 24718-24728 (2008)
   PUBMED   18566450
  REMARK    GeneRIF: The PDZ and band 4.1 containing protein Frmpd1 regulates
            the subcellular location of activator of G-protein signaling 3 and
            its interaction with G-proteins.
REFERENCE   3  (bases 1 to 4921)
  AUTHORS   Samuelson,D.J., Hesselson,S.E., Aperavich,B.A., Zan,Y., Haag,J.D.,
            Trentham-Dietz,A., Hampton,J.M., Mau,B., Chen,K.S., Baynes,C.,
            Khaw,K.T., Luben,R., Perkins,B., Shah,M., Pharoah,P.D.,
            Dunning,A.M., Easton,D.F., Ponder,B.A. and Gould,M.N.
  TITLE     Rat Mcs5a is a compound quantitative trait locus with orthologous
            human loci that associate with breast cancer risk
  JOURNAL   Proc Natl Acad Sci U S A 104 (15), 6299-6304 (2007)
   PUBMED   17404222
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and BQ201883.1.
            
            On or before Aug 15, 2019 this sequence version replaced
            XM_017593725.1, XM_017603000.1, NM_001107937.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.18822.1,
                                           SRR26360172.1486266.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               JAXUCZ010000005.1  64238730-64238855
            127-231             JAXUCZ010000005.1  64283186-64283290
            232-389             JAXUCZ010000005.1  64300167-64300324
            390-492             JAXUCZ010000005.1  64301094-64301196
            493-538             JAXUCZ010000005.1  64304758-64304803
            539-646             JAXUCZ010000005.1  64312606-64312713
            647-742             JAXUCZ010000005.1  64317119-64317214
            743-868             JAXUCZ010000005.1  64323456-64323581
            869-988             JAXUCZ010000005.1  64325084-64325203
            989-1125            JAXUCZ010000005.1  64326186-64326322
            1126-1252           JAXUCZ010000005.1  64328112-64328238
            1253-1348           JAXUCZ010000005.1  64328392-64328487
            1349-1531           JAXUCZ010000005.1  64330318-64330500
            1532-1679           JAXUCZ010000005.1  64331280-64331427
            1680-2495           JAXUCZ010000005.1  64334384-64335199
            2496-4902           JAXUCZ010000005.1  64338319-64340725
            4903-4921           BQ201883.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..4921
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..4921
                     /gene="Frmpd1"
                     /note="FERM and PDZ domain containing 1"
                     /db_xref="GeneID:313244"
                     /db_xref="RGD:1305229"
     exon            1..126
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            127..231
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..4780
                     /gene="Frmpd1"
                     /codon_start=1
                     /product="FERM and PDZ domain-containing protein 1"
                     /protein_id="NP_001101407.2"
                     /db_xref="GeneID:313244"
                     /db_xref="RGD:1305229"
                     /translation="MEELEGGLSQTRKAHRIEQMVARWLRRSRDSSARAKVAAADGPP
                     GNPAQALTAVQHTVTLDKDVLLQNYGFHISETLPLTVVAVTAGGSAHGKLFPGDQILQ
                     MNKELAEDLSCERAVDILRETEDALSITVVRCTSGVPKSSFLTEEKRARLKTNPVKVH
                     FAEEVLVSGHSQGNSLLCMPNVLKVYLENGQTKAFKFEANTTVKDIILTVKEKLSIRS
                     IEYFALALEEQYSISRLHLLHEEELIQQVVEREESQDSRCLFRVCFVPKDPLDLLKED
                     PVAFEYLYLQSCSDVLQERFAVEMKCNSALRLAALHIQERIYACAQPQKISLKYIEKD
                     WGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLEPRQKQLISAAQLRLNYLQILGE
                     LKTYGGKIFNATLMLQDRESYIALLVGAKYGISQIINSKLNIMSTLAEFANISRVELT
                     EESEKVSVVKIYLQDVKVLTLLLESSSAKDLTCLIAGYYRLFVDPANPVFLWSGNRQQ
                     THRVSAEEGYESRACSDSEESSEVDCVLEPLSDRCLVKLSLCRPFVREEQRPGDSPTP
                     EVTRRGPSTCGASSMTDSAESEASDSANTESRGCRTSGSSESMDALEEDDLDACSSSG
                     TSFFHFGPPGFSKDLDTNSQEENSRVETSGFLCLLDLAQNATSRCQKIEGPQSLASEA
                     CSWGPELSMGRLDPRLYEGSRTDYYSLCSSVSPGSHLSDSGSESTTSRQGAAPPPWCP
                     QDWMETQSGSMLETLALPALPTLALEDGSSDEEYYDAADKLTPPDTLSGPRAADLSAM
                     RLQSHSRTRGSEESLHPDPEGGEPSRQGGVKKYAKSPRKRRSFLQTDHTSQVSFPMEP
                     SASQENMDDVCYYDREPYLSLTAPSPTVSSLQDMKSEPGLLETKALGLLASLRETKSK
                     NPASRIMEMEPETMETKSVIDSRVSSISAIRLRIDPGNTENLEASPSAVTTDGSSASI
                     PHNPHPSNPGSSSPQAAQVRPLQSISPGQDAGGTTPKGLTAEPQDSTFPLSSADPNPD
                     TPGPHHAPQGDTSELEEVRSEMGSGSVLINHIQEVTPQIAGPLCPSDGPTTSGEHGVT
                     SEEMALDAAEVRQENAPSLFHKGFGKDSGHFKGDGLDNIPQALDDANATTGEIGSSLC
                     SEPPATGLGRISPNSEGENQVAQEQELLAELDLGPNFLLGEQTIQSAVLPELVEAEQL
                     DHVIGEDSVPVDTSQQVCVHTVPPLPKLSPCQEEPRSADSGHGSPAESKGDSPITCLP
                     PERSFLCFAPESQPESSNSLSRVTSFSFAGMNEVVPAGIGIEHCRCQFPYATCFRGLQ
                     PETEEEDGDPQSHPAAPLTSPPSAGSQVTLPWRAARAYSCTTPLPRKSHIWPEYCSRA
                     LRQLKTAPANAPEGFVQLTESLLELQDILEASWGVGNKHPPDKCTWHFSESRSRLCMG
                     SQKLLSSCQHVIRMDQSPEEMQGAVRVTFQHLVQLAGLCFQFTDCSRCSTRHREVAGN
                     LRDVVYTYHQFVEAAKLTCERGYHDLSVKLLARQCTALTAAVFCLTQKFRASTAL"
     exon            232..389
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            390..492
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            493..538
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            539..646
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            647..742
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            743..868
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..988
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1125
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1126..1252
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1348
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1531
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..1679
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..2495
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2496..4903
                     /gene="Frmpd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgagccga gcccgagccg agccgctgcc cgagcctggc ccgctaccgt ggccgccgct
       61 gggcggggcg ccccagctac tgctcccgcc ggctccgcgt gcacgcgggc ggcgcctcct
      121 cctcaggtaa atggaagagc tggagggcgg tttatcccag actcggaaag cacacagaat
      181 agagcagatg gtggcaaggt ggcttcggcg ctcccgggac agctcagctc gggctaaagt
      241 cgctgccgct gatgggccac ccgggaatcc agcccaggcg ctcacggcag tgcagcacac
      301 agtgacacta gacaaagatg tcctcctcca gaactatgga ttccacattt ctgagactct
      361 ccccctcaca gtggtggctg tcacagcagg cggctctgct cacggcaagc ttttccctgg
      421 tgatcagatt ctccaaatga acaaggagct ggctgaagat ctttcgtgcg aacgagcggt
      481 cgatattctt agagaaacgg aagatgctct ttcaattaca gtcgtccgct gcacatcggg
      541 agtccccaag tcgtccttct tgactgagga gaagagggcc cggctgaaga ccaacccggt
      601 gaaggtgcac ttcgctgaag aggtgctggt cagtgggcac agccagggga actctctgct
      661 ttgtatgccc aacgtgctca aggtgtacct ggagaacgga cagaccaaag ctttcaagtt
      721 tgaggcaaac acaactgtga aggacatcat cctcacggtg aaggagaagc tgtccatccg
      781 aagtatcgag tactttgcac tggccctgga agaacagtac agcatctccc gcctacacct
      841 tttgcatgag gaggagctca tccagcaggt ggtggaaagg gaagaatcac aggactcccg
      901 ctgcctcttc agggtgtgct ttgtccccaa ggaccccctg gacctgctca aagaagaccc
      961 tgtggccttt gagtatctct acctacagag ttgcagtgat gtccttcagg agcgctttgc
     1021 cgtggagatg aagtgcaatt ctgccctccg gcttgcagcc ctgcacatcc aggagcggat
     1081 ctatgcctgt gcccagccac agaagatctc tttgaagtac atagagaaag actggggaat
     1141 agagaatttt atatctccaa ctttactccg aaatatgaaa ggcaaagaca tcaagaaagc
     1201 cattagtttc cacatgaaga gaaaccagaa tttgctggaa ccccggcaga agcaacttat
     1261 ttctgctgct cagctacgct taaattatct tcagatcctt ggagaactca agacgtatgg
     1321 cgggaaaatc tttaatgcta ctctgatgct acaggataga gaatcctaca ttgcccttct
     1381 ggtgggggcc aagtatggga ttagccagat catcaatagc aaactcaaca tcatgtccac
     1441 gctggcagag tttgccaaca tcagccgtgt ggagctgacg gaagagtctg agaaagtgag
     1501 cgtggtcaag atctaccttc aggacgtcaa ggttctgact ttgttgctgg aatccagcag
     1561 tgcaaaagac ctgacctgct tgatagctgg gtactacagg ctgtttgtgg acccggccaa
     1621 ccctgttttc ctctggtctg gaaacagaca gcagactcac cgagtgtctg ctgaagaagg
     1681 ctacgagtcc agggcctgca gcgactcaga ggagtcctct gaagtggatt gcgtactgga
     1741 gcccctttct gaccgatgcc tggtgaagct gagcctctgc agaccgttcg tcagagagga
     1801 gcagcggcct ggagacagcc ccacacctga ggtgaccagg agaggcccaa gcacctgcgg
     1861 ggccagcagc atgacagaca gtgctgaatc cgaggcatcg gactcagcca acaccgagag
     1921 ccgaggctgc aggaccagtg ggtctagtga gtccatggac gcccttgaag aggatgactt
     1981 ggatgcatgc tcctccagcg ggaccagctt cttccacttc ggcccaccag gcttctcaaa
     2041 ggaccttgat accaacagcc aagaggaaaa cagcagggtc gagaccagtg gtttcctgtg
     2101 tttgctggat ctggcccaga atgccacttc tcggtgccag aagatagaag gcccccagag
     2161 ccttgcttcg gaggcctgca gctggggacc agaactgagc atgggcaggc tagaccccag
     2221 gttgtatgag ggcagccgga cggactacta tagcctgtgt tccagcgtct ccccaggcag
     2281 ccacctgagt gactcaggct cagagagcac aacctcccgg cagggagctg cacctccacc
     2341 gtggtgccca caggactgga tggagactca atctggctcc atgctggaaa ccctggccct
     2401 gcctgctctg cccacactgg ccttggagga tggcagctct gatgaggaat actatgatgc
     2461 agctgacaag ctcacaccgc cagacacact ctcagggccc agagctgctg atctgagtgc
     2521 catgagattg cagagtcatt ctagaacccg tggctccgag gaaagcctgc atccggaccc
     2581 agagggagga gagccaagca ggcagggagg ggtgaagaag tatgccaagt ccccgaggaa
     2641 aagaaggtct ttcctacaga cagatcacac ctcccaggtc tccttcccca tggagccatc
     2701 cgcctcccaa gagaacatgg atgatgtgtg ctactatgac agagagccct acctgagcct
     2761 cactgccccc tccccaactg tgtcctccct gcaggacatg aaaagtgaac caggcctcct
     2821 ggagaccaaa gccttggggt tgctggcttc cctgagggag acaaagagca aaaatccagc
     2881 ctccaggatc atggagatgg agcctgagac catggaaacc aagtctgtca ttgactctcg
     2941 agtgtcttct atctctgcca ttcgcctccg aattgacccg ggcaacacag agaatcttga
     3001 ggccagtccc tcggctgtca ccaccgatgg ttcctcagca agcatccctc acaaccccca
     3061 tccttccaac ccaggttcct ccagcccaca ggctgctcag gtcaggcccc ttcaaagcat
     3121 atctccaggt caagacgcag ggggtaccac ccccaaaggg ctcactgcag agcctcaaga
     3181 cagcaccttc cccctctcta gtgctgaccc taatccagac accccagggc cgcaccacgc
     3241 cccccaagga gacacctcag agctggaaga agtgcgatca gaaatggggt caggatctgt
     3301 tttaataaac cacatacaag aggttacccc ccaaatcgca gggcccttgt gtcccagcga
     3361 tgggcctact actagtgggg aacacggagt gacttcggaa gagatggcct tggatgcagc
     3421 tgaagttagg caggaaaatg cccccagcct gttccataag gggtttggga aggactcagg
     3481 tcatttcaag ggtgacgggt tagataatat tccacaggcc ctcgacgatg caaatgctac
     3541 aactggtgaa ataggaagct ccctctgctc agagcctcct gcaacaggtc tgggacgaat
     3601 ctctcccaac tctgaagggg aaaaccaagt agcccaggag caggagctgt tggccgaact
     3661 agacttgggc cctaatttct tacttgggga gcagaccatt cagtcagccg tccttccaga
     3721 gctggtcgag gcagagcagc tcgaccacgt gataggagaa gactcggtcc ccgtggacac
     3781 ttctcagcag gtctgtgtcc atacagtacc acccctgcca aagctttccc cgtgtcaaga
     3841 ggagccccgc tcagcagatt caggccatgg ctccccagca gaaagcaaag gtgacagtcc
     3901 tatcacttgc cttccgcctg agaggtcttt cctgtgcttc gccccagaga gccaacctga
     3961 aagctccaac agtctcagta gggtcacctc cttcagtttc gctggcatga atgaagtggt
     4021 gcctgccggg attggcatag aacactgccg atgtcagttc ccctatgcca catgcttccg
     4081 tggtctgcag cctgagacag aggaagaaga cggggaccca cagtcacacc ctgccgcccc
     4141 tcttacctca ccaccctctg caggaagcca ggtgaccctg ccctggaggg cagcccgtgc
     4201 ctacagctgc accacacccc tgcccaggaa aagccacatc tggccagagt actgctccag
     4261 ggctctgagg cagctgaaaa ctgcccctgc aaatgcccct gagggctttg tccaactcac
     4321 agagagcctg ctggagctac aggacatttt agaagcctcc tggggggttg gaaacaaaca
     4381 cccccctgac aagtgcacct ggcatttttc agaaagccgg agccgcctgt gcatgggctc
     4441 acagaagctc ctatccagct gtcagcatgt gatcagaatg gaccagtccc ctgaggagat
     4501 gcagggtgct gtgcgggtca ctttccagca cctggtccag ctggccggcc tctgcttcca
     4561 gttcacagac tgtagccgct gttccacccg gcacagggaa gtggccggga acctgaggga
     4621 cgtggtatat acctaccacc aattcgtgga ggccgcaaaa ctcacctgtg agagaggtta
     4681 ccatgacctc agtgtgaaac tcttggcccg ccagtgcacg gccctcacag ctgctgtatt
     4741 ctgtttgacc cagaagttcc gggcatccac tgctctgtga acaggtcacc gacacagagc
     4801 ctttaccttg cctggaaggt tctccaagga gcctcttcta gttcacccac tcctttaaat
     4861 gtttacgtca tagagtatta aaataaactg ctgcttaatc ttgaaaaaaa aaaaaaaaaa
     4921 a
//
