LOCUS       NM_001415086           15779 bp    mRNA    linear   ROD 27-JUN-2023
DEFINITION  Rattus norvegicus Fraser extracellular matrix complex subunit 1
            (Fras1), mRNA.
ACCESSION   NM_001415086 XM_039091668
VERSION     NM_001415086.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 15779)
  AUTHORS   Wang F, Yang Y, Lin X, Wang JQ, Wu YS, Xie W, Wang D, Zhu S, Liao
            YQ, Sun Q, Yang YG, Luo HR, Guo C, Han C and Tang TS.
  TITLE     Genome-wide loss of 5-hmC is a novel epigenetic feature of
            Huntington's disease
  JOURNAL   Hum Mol Genet 22 (18), 3641-3653 (2013)
   PUBMED   23669348
REFERENCE   2  (bases 1 to 15779)
  AUTHORS   Caruana G, Farlie PG, Hart AH, Bagheri-Fam S, Wallace MJ, Dobbie
            MS, Gordon CT, Miller KA, Whittle B, Abud HE, Arkell RM, Cole TJ,
            Harley VR, Smyth IM and Bertram JF.
  TITLE     Genome-wide ENU mutagenesis in combination with high density SNP
            analysis and exome sequencing provides rapid identification of
            novel mouse models of developmental disease
  JOURNAL   PLoS One 8 (3), e55429 (2013)
   PUBMED   23469164
REFERENCE   3  (bases 1 to 15779)
  AUTHORS   Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C,
            Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D,
            Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N,
            Kimata K, Hayashizaki Y and Sekiguchi K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   4  (bases 1 to 15779)
  AUTHORS   Petrou P, Pavlakis E, Dalezios Y and Chalepakis G.
  TITLE     Basement membrane localization of Frem3 is independent of the
            Fras1/Frem1/Frem2 protein complex within the sublamina densa
  JOURNAL   Matrix Biol 26 (8), 652-658 (2007)
   PUBMED   17596926
REFERENCE   5  (bases 1 to 15779)
  AUTHORS   Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C and
            Chalepakis G.
  TITLE     Spatiotemporal distribution of Fras1/Frem proteins during mouse
            embryonic development
  JOURNAL   Gene Expr Patterns 7 (4), 381-388 (2007)
   PUBMED   17251066
REFERENCE   6  (bases 1 to 15779)
  AUTHORS   Kiyozumi D, Sugimoto N and Sekiguchi K.
  TITLE     Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1,
            and Frem2 at the basement membrane provokes Fraser syndrome-like
            defects
  JOURNAL   Proc Natl Acad Sci U S A 103 (32), 11981-11986 (2006)
   PUBMED   16880404
REFERENCE   7  (bases 1 to 15779)
  AUTHORS   Jadeja S, Smyth I, Pitera JE, Taylor MS, van Haelst M, Bentley E,
            McGregor L, Hopkins J, Chalepakis G, Philip N, Perez Aytes A, Watt
            FM, Darling SM, Jackson I, Woolf AS and Scambler PJ.
  TITLE     Identification of a new gene mutated in Fraser syndrome and mouse
            myelencephalic blebs
  JOURNAL   Nat Genet 37 (5), 520-525 (2005)
   PUBMED   15838507
REFERENCE   8  (bases 1 to 15779)
  AUTHORS   Petrou P, Pavlakis E, Dalezios Y, Galanopoulos VK and Chalepakis G.
  TITLE     Basement membrane distortions impair lung lobation and capillary
            organization in the mouse model for fraser syndrome
  JOURNAL   J Biol Chem 280 (11), 10350-10356 (2005)
   PUBMED   15623520
REFERENCE   9  (bases 1 to 15779)
  AUTHORS   Smyth I, Du X, Taylor MS, Justice MJ, Beutler B and Jackson IJ.
  TITLE     The extracellular matrix gene Frem1 is essential for the normal
            adhesion of the embryonic epidermis
  JOURNAL   Proc Natl Acad Sci U S A 101 (37), 13560-13565 (2004)
   PUBMED   15345741
REFERENCE   10 (bases 1 to 15779)
  AUTHORS   McGregor L, Makela V, Darling SM, Vrontou S, Chalepakis G, Roberts
            C, Smart N, Rutland P, Prescott N, Hopkins J, Bentley E, Shaw A,
            Roberts E, Mueller R, Jadeja S, Philip N, Nelson J, Francannet C,
            Perez-Aytes A, Megarbane A, Kerr B, Wainwright B, Woolf AS, Winter
            RM and Scambler PJ.
  TITLE     Fraser syndrome and mouse blebbed phenotype caused by mutations in
            FRAS1/Fras1 encoding a putative extracellular matrix protein
  JOURNAL   Nat Genet 34 (2), 203-208 (2003)
   PUBMED   12766769
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JACYVU010000248.1.
            
            [WARNING] On Mar 31, 2024 this sequence was replaced by
            NM_001415086.2.
            
            On Dec 21, 2022 this sequence version replaced XM_039091668.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132296, SAMEA5756307
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-928               JACYVU010000248.1  8661935-8662862     c
            929-960             JACYVU010000248.1  8651509-8651540     c
            961-1068            JACYVU010000248.1  8508734-8508841     c
            1069-1161           JACYVU010000248.1  8501681-8501773     c
            1162-1321           JACYVU010000248.1  8493667-8493826     c
            1322-1455           JACYVU010000248.1  8491999-8492132     c
            1456-1539           JACYVU010000248.1  8484840-8484923     c
            1540-1641           JACYVU010000248.1  8482750-8482851     c
            1642-1833           JACYVU010000248.1  8482261-8482452     c
            1834-1923           JACYVU010000248.1  8477841-8477930     c
            1924-1959           JACYVU010000248.1  8475335-8475370     c
            1960-2107           JACYVU010000248.1  8473790-8473937     c
            2108-2251           JACYVU010000248.1  8472293-8472436     c
            2252-2386           JACYVU010000248.1  8470655-8470789     c
            2387-2530           JACYVU010000248.1  8456714-8456857     c
            2531-2671           JACYVU010000248.1  8449492-8449632     c
            2672-2812           JACYVU010000248.1  8446918-8447058     c
            2813-2989           JACYVU010000248.1  8445140-8445316     c
            2990-3130           JACYVU010000248.1  8431678-8431818     c
            3131-3274           JACYVU010000248.1  8427809-8427952     c
            3275-3427           JACYVU010000248.1  8406871-8407023     c
            3428-3574           JACYVU010000248.1  8406236-8406382     c
            3575-3721           JACYVU010000248.1  8397764-8397910     c
            3722-3862           JACYVU010000248.1  8395225-8395365     c
            3863-4003           JACYVU010000248.1  8394463-8394603     c
            4004-4144           JACYVU010000248.1  8393083-8393223     c
            4145-4415           JACYVU010000248.1  8390003-8390273     c
            4416-4500           JACYVU010000248.1  8385579-8385663     c
            4501-4827           JACYVU010000248.1  8381979-8382305     c
            4828-4981           JACYVU010000248.1  8372064-8372217     c
            4982-5169           JACYVU010000248.1  8366350-8366537     c
            5170-5286           JACYVU010000248.1  8362490-8362606     c
            5287-5401           JACYVU010000248.1  8357102-8357216     c
            5402-5539           JACYVU010000248.1  8355147-8355284     c
            5540-5572           JACYVU010000248.1  8352982-8353014     c
            5573-5704           JACYVU010000248.1  8348701-8348832     c
            5705-5830           JACYVU010000248.1  8347541-8347666     c
            5831-6078           JACYVU010000248.1  8344937-8345184     c
            6079-6227           JACYVU010000248.1  8339825-8339973     c
            6228-6390           JACYVU010000248.1  8339489-8339651     c
            6391-6526           JACYVU010000248.1  8337774-8337909     c
            6527-6717           JACYVU010000248.1  8332741-8332931     c
            6718-6871           JACYVU010000248.1  8331569-8331722     c
            6872-7135           JACYVU010000248.1  8330162-8330425     c
            7136-7324           JACYVU010000248.1  8327890-8328078     c
            7325-7444           JACYVU010000248.1  8326396-8326515     c
            7445-7624           JACYVU010000248.1  8325967-8326146     c
            7625-7749           JACYVU010000248.1  8315679-8315803     c
            7750-7890           JACYVU010000248.1  8315301-8315441     c
            7891-8118           JACYVU010000248.1  8314058-8314285     c
            8119-8232           JACYVU010000248.1  8311169-8311282     c
            8233-8383           JACYVU010000248.1  8308786-8308936     c
            8384-8543           JACYVU010000248.1  8307603-8307762     c
            8544-8712           JACYVU010000248.1  8305788-8305956     c
            8713-8959           JACYVU010000248.1  8303447-8303693     c
            8960-9304           JACYVU010000248.1  8301856-8302200     c
            9305-9465           JACYVU010000248.1  8299803-8299963     c
            9466-9613           JACYVU010000248.1  8298286-8298433     c
            9614-9819           JACYVU010000248.1  8292982-8293187     c
            9820-9976           JACYVU010000248.1  8289384-8289540     c
            9977-10177          JACYVU010000248.1  8286824-8287024     c
            10178-10365         JACYVU010000248.1  8284057-8284244     c
            10366-10641         JACYVU010000248.1  8282747-8283022     c
            10642-10874         JACYVU010000248.1  8277203-8277435     c
            10875-11035         JACYVU010000248.1  8275006-8275166     c
            11036-11250         JACYVU010000248.1  8271460-8271674     c
            11251-11401         JACYVU010000248.1  8268993-8269143     c
            11402-11509         JACYVU010000248.1  8267671-8267778     c
            11510-11669         JACYVU010000248.1  8266595-8266754     c
            11670-11786         JACYVU010000248.1  8265723-8265839     c
            11787-11953         JACYVU010000248.1  8261675-8261841     c
            11954-12159         JACYVU010000248.1  8260239-8260444     c
            12160-12306         JACYVU010000248.1  8258033-8258179     c
            12307-15779         JACYVU010000248.1  8253543-8257015     c
FEATURES             Location/Qualifiers
     source          1..15779
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..15779
                     /gene="Fras1"
                     /note="Fraser extracellular matrix complex subunit 1"
                     /db_xref="GeneID:289486"
                     /db_xref="RGD:1306516"
     exon            1..928
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     CDS             856..12900
                     /gene="Fras1"
                     /note="extracellular matrix protein FRAS1; Fraser syndrome
                     1; extracellular matrix protein FRAS1-like; extracellular
                     matrix organizing protein FRAS1"
                     /codon_start=1
                     /product="extracellular matrix organizing protein FRAS1
                     precursor"
                     /protein_id="NP_001402015.1"
                     /db_xref="GeneID:289486"
                     /db_xref="RGD:1306516"
                     /translation="MGVFKAWLGVALALAEFAVLPHCEGACLYRGSLLADATIWKPDS
                     CQNCRCHGDIVICKPVVCKNPRCAFEKGEVLWIAPNQCCPQCAPRTPGSCHHEGKIRE
                     HGTEWASGPCTLCSCTYGEVRCSHQQCTPLSCGPQELEFLAEGHCCPICVGTGKPCSD
                     DGHVFQDGEDWPLSHCAKCVCRNGLTQCFTAQCQPLFCNQDEIVVRVPGKCCSQCSSR
                     SCSTAGQVYEHGEQWKEDACTLCMCDQGQVRCHKQACPPLRCAKGQSKARHHGQCCEE
                     CVSPVRSCSSGGVLRYQDEMWKGSACEFCVCDQGQVTCQTGECAKVACAPGEELVHLE
                     GKCCPECISRNDYCVYEEKAEIMSSNSSEIKHVPEGKKWEEGPCKLCECREAQVTCYE
                     PSCPPCPVATLAMAVKGQCCPDCTPVHCHPDCLTCSHSPEHCDLCQDPTKLLQNGRCV
                     PSCGLGFYQAGSLCLACQPQCSTCTSSLECSSCLPPLLMQQGQCVSTCGDGFYQDHHS
                     CAVCHESCAGCWGPTEKHCVACRDPLLVLRDGSCENTCGNGFYNRQGTCVACDQSCKS
                     CGPSSPRCLTCAEKTVLYDGTCISECPRGYYADATGRCKVCHVSCASCSGPAAAHCTA
                     CVHPQVLRQGHCLPSCGGGFYPDHGICGACHGSCHTCVGPEPTHCTQCKKPEAGLQVE
                     QHSGENVPYGKCVSQCGAHFYLESTGLCEACHPSCLLCEGKSPRNCTGCGPAHVLLAG
                     RCLSQCPETHFNQEGTCTECHPSCRQCHGPLESDCVSCHPHLTLSSGRCKASCKDEQF
                     LNLVGYCADCHPLCQHCVANLQDTGSVCLKCQHARHLLLGDHCVPDCPPGHYKERGTC
                     KRCHPSCRSCQNGGPFSCSSCNTGLVLTHIGACSSTCFPGHYLDDNQACQPCNRHCRS
                     CDSQGSCTSCRDPSKVLLFGECQYESCAPQYYLDISTKTCKECDWSCNACTGPLRTDC
                     LQCMDGYVLQDGVCVEQCSPQHYRDSGSCKRCDSHCLQCQGPHECTRCEGPFLLFRAQ
                     CVQECAKGYFADHAEHKCTACPQGCLQCSHKDRCHLCDHGFFLKSGFCMPTCVPGFSG
                     HSSNETCTDKVYTPSLHVNGSLTLGIGSMKPLDFSLLNIQHQDGRVEDLLFHIVSTPT
                     NGQLLLSRNGKEVQLEKAGHFSWKDVNGKKVRFVHSKEKLRKGYFSLKISDQQFFSEP
                     QLINIQAFSTQAPYVLRNEVLHISKGERAAITTQLLDIRDDDNPQDVVLNVLDPPRHG
                     QLLRTPPAPAASVYQFHVDELSRGLLLYAHDGSDSTSDIIVFQANDGHSFQNILFRVK
                     NVPKNDRALRLVTNSMVWVPEGGMLKITNRILRAQAPGVRADDIIYKITHDHPQFGEV
                     VLLMNLPADSPAGPAEEGHHLPDGRMTTPVSTFSQQDIDDGIVWYRHSGATAQSDSFH
                     FQVSTATNAQEHPQSHMFNIAILPQALEAPKLSLGTSLHMTAREDGLSVIHPQSLSFG
                     KAESPSGKIIYNITVPLHPNQGVIEHRGRPNSPIRYFTQEEINQGQIMYRPPAAPPHL
                     QEFMAFSFAGLPESVRFYFTVSDGQHTSPEMALTIHLLHSDRQPPAFQIKAPLLEVSP
                     GGRTPLGLQLVVRDAEVVPEELFFQLQKPPQHGMLMKYTAKSSVTMSAGDTFTYDEVE
                     RNVLQYVHDGSPAWEDNMEISVTDGLTVTTSEVKVEVSPSENREPRLAPGSSLSMTVA
                     SQHTAIITRSHLAYVDDSSPDSEIWIQLSSLPLYGVLLKTSGPDMEELSGDSNFTMED
                     INSKNIRYSAVFETEGQSVTDGFHFSVSDMDNNRVDNQVFTITVTPAENPPHIIAFAD
                     LITVDEGGRAPLSLHHFFATEDQDNLQGDAVIKLSALPKYGCIENTGTGDRFGPGANS
                     ELEASFPIQDVLENYIYYFQSVHESIEPTHDVFSFYVSDGSGRSEIHSINITIERKND
                     EPPRMTLRPLGVRLSSGVAISNSSLSLQDLDTPNNELIFVLMKKPDHGYLLLRPTASD
                     PLENGTVLDQGSSFTYQDILAGLVGYLPGDIYMAVDEFRFSLTDGLHVDTGRMEIYIE
                     LPTSNIPHLAINRGLQLSAGSVARITEQHLRATDTDSEAGQLVYIVKEDPGAGHLQMT
                     KADKLEQISVRGPIRSFTQADVSQGQIEYSHGPGEAGGSFAFKFDVVNGEGNKLADQS
                     FSINVLEDKSPPVIITNKGLVLDENSVEKITTAQLLATDQDSKPTELIYRITSQPQLG
                     HLEHVASPGIQISSFTQADLTSRNVQYVHSSGTGKLSDAFSFVLSDGLHEVTQTFSIT
                     IHPVDDSLPLVQNRGMRVQEGVRKTITEFELKAVDVDTEAESITFTIVQPPRHGTIER
                     TARGQRYQLTSSFTMEDIYQNRVSYSHDGSNSLKDRFTFTVSDGTNPFFIIEEGGEEI
                     MTAAPQQFLVDILPVDDGTPRIVTNLGLQWLEYMDGKATNLITKKELLTVDPDTEDSQ
                     LTYEVTTGPMHGYVENKLQPGRVAATFTQEHVNLGLIRYVLYEEKIQKMMDSFQFLVK
                     DSKPNVVSDNIFYIHWSLISFKYTSYNVSEKAGSVSVMVQRTGNLNQYAIVLCRTEQG
                     TASSSSRVSSHPGQQDYVEYAGQVQFDEREDTKSCTIVINDDDVFENIESFTVELSMP
                     AYALLGEFTQAKVIINDTEDEPTLEFDKKTYRVNESAGFLFAPIKRQGDPSSAVSAIC
                     YTVPKSAMGSSLYALESGSDFKSRGRSVESRVLLGPGVTTSTCDVMVIDDSEYEEEEE
                     FEIALADASNNARIGRLAVAKVLISGPNDASTVSLGNTAFTISEDAGTVKVPVIRHGT
                     DLSTFTSVWCATRPSDPASATPGVDYVPSSRKVEFGPGVTEQYCTLTILDDTQYPVIE
                     GLETFVVFLSSAQGAELTKPSQAVIAINDTFQDVPSMQFSKDLLLVKEKEGVLHIPII
                     RSGDLSYESSVRCYTQSHSAQVMEDFEERRNADSSRITFLKGEKAKNCTVYIHDDSMF
                     EPEEQFRVYLGHPLGNHWSGARIGKNSMATVTISNDEDAPTIEFEEAAHQVREPAGPD
                     ATAVLSVKVIRRGDQNRTSKIRCSTRDGSAQSGVDYYPKSRVLKFSPGVDHIFFKVEI
                     LSNEDREWHESFSLVLGPDDPVEAVLGDVTTATVTILDQEAAGSLILPAPPIVVTLAD
                     YDHVEELSKEGVKKAPSPGYPLVCVTPCDPHYPRYAVMKERCSEAGINQTSVQFSWEV
                     AAPTDGNGARSPFETITDSTPFTSVNHKVLDSIYFSRRFHVRCVAKAVDKVGHVGTPL
                     RSNVVTIGTDSAICHTPVVAGTARGFQAQSFIATLKYLDVKHKEHPNRIHISVQIPHQ
                     DGMLPLISTMPLHNLHFLLSESIYRQQHVCSNLVTARDLRGLSEAGFLDDAGLHSTAL
                     GPGYDRPFQFDPSVREPKTIQLYRHLNLKSCVWTFDAYYDMTELIDVCGGSVTADFQV
                     RDSAQSFLTVHVPLYVSYIYVTAPRGWASLEHHTEMEFSFFYDTVLWRTGIQTDSVLS
                     ARLQILRIYIREDGRLVIEFKTHAKFRGQFVIEHHTLPDVKSFILTPDHLGGIQFDLQ
                     LLWSAQTFDSPHQLWRATSSYNRKDYSGEYTIYLIPCTVQPTQPWVDPGEKSLACTAH
                     APERFLIPIAFQQTNRPVPVVYSLNTEFQLCNNEKVFLMDPNTSDMSLAEMDYKGAFS
                     KGQILYGRVLWNPEQNLHSAYKLQLEKVYLCTGKDGYVPFFDPTGTIYNEGPQYGCIQ
                     PNKHLKHRFLLLDRSQPEVTDKYFHDVPFEAHFASELPDFQVVSSMPGVDGFTLKVDA
                     LYKVEAGHQWYLQVIYIISPDSISRPRVQRSLTASLRRHQRDLVDPSGWLSLDDSLIY
                     DNEGDQVKNGTNMKSLNLELQEPVIAASLSQSGASIGSALAALMLLLLLFLVACFITR
                     KCQKQKKKQPPEDTLEEYPLNTKVDVAKKNTDKGEKNANRQYCTVRNVNILSDSEGYY
                     TFKGAKVKKLNLEVRVHNNLQDGTEV"
     exon            929..960
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1068
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1161
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1321
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1455
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1539
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..1641
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1642..1833
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..1923
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..1959
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2107
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2251
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2252..2386
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2387..2530
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2531..2671
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2672..2812
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2813..2989
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            2990..3130
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3131..3274
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3275..3427
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3428..3574
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3575..3721
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3722..3862
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            3863..4003
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4004..4144
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4145..4415
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4416..4500
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4501..4827
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4828..4981
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            4982..5169
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5170..5286
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5287..5401
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5402..5539
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5540..5572
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5573..5704
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5705..5830
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            5831..6078
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6079..6227
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6228..6390
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6391..6526
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6527..6717
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6718..6871
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            6872..7135
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7136..7324
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7325..7444
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7445..7624
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7625..7749
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7750..7890
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            7891..8118
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8119..8232
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8233..8383
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8384..8543
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8544..8712
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8713..8959
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            8960..9304
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            9305..9465
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            9466..9613
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            9614..9819
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            9820..9976
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            9977..10177
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            10178..10365
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            10366..10641
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            10642..10874
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            10875..11035
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11036..11250
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11251..11401
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11402..11509
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11510..11669
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11670..11786
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11787..11953
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            11954..12159
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            12160..12306
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
     exon            12307..15779
                     /gene="Fras1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgagttcg gaggcgtctt ttctaacccc tctctttcct cggtgcatct acaattatgg
       61 ctccacctcc acttgggtaa tcgcacctcc gccctgcagc gcagctcggg ggtgcacggt
      121 gcggggaggt gggcgtcggt gtggagcaag ccgcgcccct cagcactcct cctctcggct
      181 aggggcgggg gctagaaagt ggcagcagcg ccccccgcgc cacctttcgc gtggagctct
      241 ggaagcgcct gcagcagccg ggcggcgtgg tgcggtgcgg ctgcagcgcc ccggagtccc
      301 ggagctcctg cagggccgca caaagtttgc agccagcggc cctgcacggc cgagctccct
      361 gagcgctgct gtggcccggc cccgtgtgtt cgcggcgacc gccctcggcc gatgctacac
      421 cgacagacgg gggcgtgccg agagaacttt gaaaagctgt cgagaaggaa cctgcgcctg
      481 cagctcgcca gttggggacc tcgggaggaa ctggtctaac ccgaggcaat gctgcgggat
      541 cccagcagcc actgacctgc aactttcctg cttagactta gcggcggttt aagctttgcc
      601 tcctcctcgc aggctcggct caccttggtg gccgctctgc gggagagcag agtgagcctc
      661 ccggctgact gagggttgca gtcggcggca tccttctccg gtccacccgg ccaacctcgg
      721 ctcccggccg agcagacccg cgcttcccca ctatctgcgg gtcccggctc ccggcgccgc
      781 agcctggggt ttggaggaga gcaggttctt ggatgctgaa ggctgggctc ctcctgcgag
      841 agtgtcgcgg cggcgatggg tgtcttcaaa gcgtggctcg gggtggccct agcgctggcg
      901 gaatttgcag tattgcctca ttgcgaaggt gcttgcctgt atcggggctc cttgcttgcg
      961 gatgccacaa tttggaagcc tgattcatgc cagaactgcc gttgccatgg tgatattgtg
     1021 atctgcaaac ctgttgtttg caaaaaccct cggtgtgcct ttgagaaggg agaagtgctg
     1081 tggatcgccc ccaaccagtg ctgcccacag tgtgcaccca ggactcccgg ctcttgtcac
     1141 catgagggaa aaatccgtga gcatggcaca gagtgggcct caggtccatg tactttgtgc
     1201 tcttgcacct atggagaggt gagatgctcg caccaacaat gcaccccatt atcatgtgga
     1261 ccacaggagc tagaattcct tgctgaagga cactgctgcc ctatctgtgt gggcactggg
     1321 aaaccctgtt ccgatgatgg ccacgtgttt caagatggag aggattggcc actgagccac
     1381 tgtgccaagt gtgtatgcag aaatgggctc actcagtgct ttacagccca gtgtcaacct
     1441 ctattttgta accaggatga aatcgtcgtc cgggtccctg gaaaatgctg ctctcagtgc
     1501 tcctcgcggt cctgctcgac agctggccaa gtgtacgagc atggcgaaca gtggaaagaa
     1561 gatgcctgca ccctgtgtat gtgtgaccag ggacaggtca ggtgccacaa acaggcctgc
     1621 ccgccactga gatgtgcaaa gggtcagagc aaagcccggc atcacgggca gtgctgtgag
     1681 gaatgtgtgt ctcctgtcag aagttgctca tccggtgggg tcctgcggta ccaggatgaa
     1741 atgtggaagg gctcggcctg tgagttctgc gtgtgtgacc agggccaagt gacctgccag
     1801 acaggagagt gtgccaaggt ggcctgtgcc ccgggtgaag aattagttca cttagaggga
     1861 aaatgctgcc cagaatgcat ttcgaggaat gattattgtg tttatgaaga gaaggcagag
     1921 attatgtctt caaattcgag tgaaattaag catgttccag aggggaagaa gtgggaagaa
     1981 ggcccttgta aactgtgtga atgccgggag gctcaagtta cttgctatga gccatcttgc
     2041 ccaccgtgtc cagtggctac cttagccatg gcggtgaagg gacaatgctg tcccgactgc
     2101 acaccagttc actgccaccc agactgcttg acctgctctc actctccaga gcattgtgac
     2161 ctctgccagg atcccacgaa gctgctgcag aatgggcgat gtgtgcctag ctgtggtctg
     2221 ggcttttacc aagcaggcag cctttgttta gcctgccagc cccagtgctc cacatgcacc
     2281 agcagcctgg agtgttcatc ttgcctgcct cccctgctga tgcagcaggg acagtgtgtg
     2341 tctacctgcg gggatggttt ctaccaagat caccactctt gtgcagtctg tcatgagtcc
     2401 tgtgcaggtt gctggggtcc cacagagaag cactgtgtgg cctgcagaga cccactgctg
     2461 gtgctgagag acggcagctg tgagaacacc tgtggcaatg gcttctacaa caggcagggg
     2521 acctgcgttg cttgtgacca atcctgtaag agctgtggcc ccagtagtcc cagatgtctt
     2581 acctgtgctg agaagacagt gttatatgat gggacgtgca tttctgaatg ccctcgtggc
     2641 tactatgctg atgccactgg aagatgcaaa gtttgtcacg tgtcctgtgc cagctgctct
     2701 gggccagcag ctgctcactg tacggcctgc gtccatcccc aggttcttcg tcaaggccac
     2761 tgtctgccaa gctgtggagg aggcttctac cctgaccatg ggatctgtgg agcctgccat
     2821 ggctcctgcc acacgtgtgt gggtcccgag cccactcatt gtacccagtg taagaagcca
     2881 gaggcaggac tccaggtgga gcagcactca ggggaaaatg tcccctatgg caagtgtgtt
     2941 tctcagtgtg gagcccactt ttacttggag agcactggac tatgtgaagc ttgccaccca
     3001 tcctgcctcc tgtgtgaagg gaagagccct cgcaactgca caggctgtgg gcctgcccac
     3061 gtgctgctgg ctgggcgctg cctctcccag tgtccagaga cccactttaa ccaggaaggt
     3121 acttgtacag agtgccaccc atcatgcagg cagtgccatg ggcctctgga atcggactgt
     3181 gtatcctgcc accctcacct tactctctcc agtgggcgct gtaaggccag ctgcaaggat
     3241 gagcaattcc tgaaccttgt cgggtattgt gctgactgcc atcctctgtg ccagcactgt
     3301 gtggccaatc tccaagacac tggtagcgtg tgcctaaagt gccagcatgc ccgccacctg
     3361 ctgcttggag atcactgcgt tccagactgc cctcctggac actataaaga gagaggcact
     3421 tgtaaaagat gccatccctc ctgcagaagc tgccagaatg gagggccttt ctcctgctcc
     3481 tcttgcaaca ctggtctggt tctgacccac attggtgcct gcagctccac ctgcttccct
     3541 gggcattatc tggatgataa ccaagcttgc cagccatgca acaggcattg tagaagctgt
     3601 gattcacagg gcagctgcac ctcctgccga gacccaagca aggtcctgct atttggggaa
     3661 tgccagtatg agagctgcgc cccccagtac taccttgaca tctccaccaa gacttgcaaa
     3721 gagtgtgatt ggagttgcaa cgcctgtacc gggcctctcc gaacagactg cctgcaatgc
     3781 atggacggct atgtcctcca ggatggtgtg tgcgtggagc agtgttcacc acagcactac
     3841 cgggactccg gctcctgtaa gcgctgtgac agccactgtc tccagtgcca gggcccccac
     3901 gagtgcacac gctgcgaagg gccatttctt ctcttcagag cccagtgtgt tcaggaatgt
     3961 gcaaaaggat actttgcaga ccacgccgaa cacaaatgca cagcctgccc tcagggatgc
     4021 ttgcagtgca gccacaaaga tcggtgccac ttatgcgacc acggtttctt cctgaagagt
     4081 ggcttctgca tgcccacctg tgtccctggt ttctctggcc actcatctaa tgaaacctgc
     4141 actgacaaag tgtacactcc aagtcttcat gtgaatggct ccttgaccct tggaatcggt
     4201 tcaatgaagc cactggactt ttctctcctg aacatccaac accaagacgg cagagtggaa
     4261 gatctcctgt tccacattgt aagcacgccc accaatggtc agctcctgct ctcaagaaat
     4321 ggcaaagagg tccagctgga gaaggctggc cactttagct ggaaagatgt gaatgggaag
     4381 aaagtgcgct ttgtgcacag caaagagaag ctcaggaaag gctacttttc cttgaaaatt
     4441 agtgaccagc aattcttctc tgagccacag ctgatcaaca tacaagcatt ttcaacacag
     4501 gccccgtatg tgctgagaaa tgaggttctg cacatcagca aaggagagcg ggcagccatc
     4561 accacccagc tgcttgacat ccgggacgat gacaaccccc aggatgtggt cctgaatgtc
     4621 ctcgatcctc cccgtcatgg gcaattgctc cgaacgcctc cagcccctgc ggcctctgtt
     4681 tatcagttcc atgtggatga actctccagg ggcctcctcc tctatgctca tgatggctca
     4741 gacagcacat ctgatattat agtctttcag gccaatgacg gacactcctt ccaaaatata
     4801 ctgtttcgtg tgaagaatgt gcccaagaat gacagagctc tgcggcttgt gactaactca
     4861 atggtgtggg ttccggaagg ggggatgctg aagatcacca accgaatctt gcgggctcaa
     4921 gctccaggtg tcagagccga tgacatcatc tacaagatca cacacgacca cccccagttc
     4981 ggggaggtgg tcctcctgat gaatctgcct gcagacagtc cagccggtcc tgccgaggaa
     5041 gggcatcacc tgcctgatgg aaggatgacg acccccgtca gtaccttcag ccagcaggac
     5101 atcgatgatg gcattgtgtg gtacagacac tcgggagcca cggctcagag tgactccttc
     5161 cacttccagg tgtccactgc caccaatgcc caggaacacc cgcaaagcca catgttcaac
     5221 attgcaatct tacctcaggc actggaggca cctaaactct ccctgggaac atctctccat
     5281 atgactgctc gtgaagatgg actaagtgtc attcaccctc agtccttatc ctttgggaag
     5341 gcagagagtc ccagtggaaa gataatatac aacatcaccg tacctctgca tccaaaccaa
     5401 ggtgtcattg aacacagagg ccggcctaac tctcccatcc ggtatttcac tcaggaagag
     5461 ataaaccaag gccaaatcat gtaccgccct cccgcagcac ctccccacct ccaggagttc
     5521 atggccttct catttgctgg tctcccagaa tcagttagat tttacttcac agtttcggat
     5581 ggacagcaca cgagtccaga gatggccctc accattcact tactgcactc tgatcggcaa
     5641 ccaccagcct ttcagatcaa ggctcccctg ctggaagtta gccctggagg ccgtacccct
     5701 ttaggcctgc agttggtagt gagagatgct gaggtggtgc ctgaagaact cttcttccag
     5761 cttcagaaac ctccacagca tggcatgctc atgaagtaca cagcaaagtc ctcagtgacc
     5821 atgtctgcag gtgacacttt cacctatgat gaagttgaga gaaacgttct gcagtacgta
     5881 cacgatggct cccctgcctg ggaggacaac atggagatct cagtcacaga tggcctgacg
     5941 gtgacaacct cagaagtaaa agtggaggtg tccccgtcgg agaaccgaga gcccaggctg
     6001 gcccccggct cctccctgag catgactgtt gctagtcaac acacagccat aatcaccagg
     6061 tcacaccttg cgtatgtgga tgactcttcc cctgactcag agatctggat tcagttaagt
     6121 tctctgccat tgtacggtgt gctcttaaag acctcaggac ctgacatgga ggagctctca
     6181 ggggattcca atttcaccat ggaggacatc aacagtaaga acattaggta ctctgctgtg
     6241 tttgagacgg aagggcaatc ggttacagat ggcttccact tctctgtctc agacatggac
     6301 aacaaccgtg tggacaacca ggtctttacc atcacggtca ctcctgccga gaaccctcct
     6361 cacatcattg cctttgctga ccttatcacg gtcgatgagg gagggagagc accactctcc
     6421 ctccaccact tctttgccac tgaagatcag gacaaccttc agggggacgc tgtcattaag
     6481 ctaagtgctc tgcccaagta tggctgcatt gagaacacag gaacaggaga ccgctttggc
     6541 ccaggagcaa acagtgagct ggaggcgtca ttccctattc aagacgtcct ggaaaactac
     6601 atttactatt ttcagagtgt tcacgaaagc atcgagccca cccatgacgt gtttagcttt
     6661 tatgtgagcg acggaagcgg tcgctctgaa attcacagca ttaatatcac catcgagagg
     6721 aagaatgacg agcctcccag gatgacccta cgacccctgg gagtacggct aagctcggga
     6781 gtggcgataa gcaattcttc cttgagccta caagatctgg acaccccaaa taacgagctg
     6841 atttttgtat tgatgaaaaa gcctgaccac ggttacctac tcctgaggcc tactgcctct
     6901 gaccctctag aaaatgggac ggttttagac caaggctcct ccttcaccta tcaggatatc
     6961 ctggccgggc tggtcgggta cttacccggt gatatctaca tggcagtaga tgagttccgg
     7021 ttctcgctca cggatggcct ccatgtagac acagggagga tggagatcta catagaactg
     7081 cccacaagca acattcccca tttggcaata aaccgaggac ttcagctctc agcagggtct
     7141 gtagcacgca tcacagagca gcacttgaga gcgacagaca ctgactcgga ggctggccag
     7201 cttgtgtaca tcgtgaagga agaccctgga gcagggcatc tacagatgac taaggctgac
     7261 aaactggagc agatctctgt tagaggcccc atccggagct tcacccaggc agacgttagc
     7321 caagggcaga tagaatacag ccacggacca ggagaagctg gtgggagctt tgcttttaaa
     7381 ttcgacgtgg ttaatgggga aggcaataag ttggctgacc aatcattttc catcaatgtt
     7441 ttagaagaca aatccccacc agtcatcatc accaataaag ggctggtctt ggacgagaac
     7501 tctgtggaga aaatcacgac tgcacagctg ttggccaccg accaggacag caagcctacg
     7561 gaactcatct acagaatcac cagccagccc cagttgggcc acctggaaca tgtggcctcc
     7621 ccaggcatcc agattagttc ctttactcaa gctgacctga cttcacgaaa tgttcaatat
     7681 gtccattcta gtgggaccgg gaaactatca gatgccttca gcttcgtgct gtccgatggc
     7741 ttgcatgagg tgacacagac cttctccatc acaattcacc ctgtggatga ttcactgccc
     7801 cttgtgcaga accgaggcat gcgtgtgcaa gagggtgtga ggaagaccat cacagagttt
     7861 gagctgaagg cagtggatgt ggacacagag gctgagtcta tcaccttcac cattgtgcag
     7921 cccccacgcc atggcaccat tgagagaact gccaggggcc agcgctacca gctcacgtcc
     7981 tccttcacta tggaagacat ctaccagaac cgtgtcagct atagccatga cggcagcaac
     8041 tccctcaaag accgatttac cttcaccgtt tctgatggga ccaacccctt ctttatcatt
     8101 gaggaaggag gagaagagat catgacagca gccccgcagc agttccttgt ggacatcctc
     8161 ccggtggatg acggcacccc tagaattgtc accaacctgg ggctccagtg gctggagtat
     8221 atggatggca aggcaaccaa cctgatcacc aagaaggaac tgctgaccgt ggacccagac
     8281 accgaggact cacagcttac ctatgaggtc acgacaggcc ccatgcatgg ttacgtggag
     8341 aacaagctgc agccgggcag agttgcggcc accttcaccc aggagcatgt gaacttgggg
     8401 ttgattcgtt atgtgttata tgaggagaag atccagaaaa tgatggacag ttttcagttc
     8461 ctggtgaagg acagtaagcc caatgtggtc agcgacaaca tcttctatat ccactggtct
     8521 ctcatcagct ttaaatatac cagctataat gtcagcgaga aggcgggctc cgtcagtgtc
     8581 atggtgcaga ggactggaaa cctgaaccag tatgccatcg tcctgtgtcg aacggaacaa
     8641 ggcacagcca gctccagctc cagggtcagc tctcatcccg gacagcagga ctacgtggag
     8701 tatgctggcc aggtgcagtt tgacgaacga gaggacacaa agtcctgcac cattgtcatc
     8761 aacgatgatg acgtatttga gaatattgaa agtttcaccg tggagctcag catgccagcc
     8821 tatgccctgc tgggagagtt cacccaggcg aaggtcatta tcaatgacac tgaggatgag
     8881 cccacattag agttcgataa gaagacctac cgggtcaacg agagcgctgg atttctgttt
     8941 gcacccatca agagacaagg agacccaagc agcgcggtgt ctgccatttg ctacacggtt
     9001 ccaaagtcag ccatgggaag cagcctctat gctctggagt caggatccga cttcaagtcc
     9061 agagggaggt ctgttgagag tcgtgtgcta ctgggacccg gtgtcaccac gtccacatgt
     9121 gatgtgatgg ttatcgatga cagcgagtat gaggaggaag aggagtttga gatagccctg
     9181 gctgatgctt ctaacaatgc ccgcattgga aggctggcag tggccaaggt cctcattagt
     9241 ggtcccaacg atgcctcaac tgtctccctg ggcaacacag ctttcaccat cagtgaggat
     9301 gcaggcacag tgaaggtccc agtcatccgc catggcactg acctttctac cttcacatct
     9361 gtctggtgtg ccacacggcc ctcagaccca gcgtctgcca ctccaggagt cgactatgtc
     9421 cccagctcaa ggaaggtgga atttgggcca ggtgtcaccg agcagtactg cactttgact
     9481 atcttggacg acacacaata cccagtaatc gaaggactgg agacatttgt ggttttcctc
     9541 agctcagcac aaggagccga actgaccaaa ccctcccagg ctgtcattgc aattaatgac
     9601 acattccagg atgttcccag catgcagttt tccaaggatt tgcttctagt gaaggaaaag
     9661 gagggtgtcc tgcacattcc catcatccgg agcggggacc tgagctacga gtcctcagtg
     9721 aggtgttaca ctcaaagcca ctccgctcag gtcatggagg acttcgaaga gagaagaaac
     9781 gcagactctt cacggattac gtttctgaaa ggggagaagg caaagaactg cacagtctac
     9841 atccatgatg actccatgtt tgagcctgag gagcagttcc gggtctacct tggccaccct
     9901 cttggaaacc actggagtgg agcaagaatt gggaagaata gcatggccac tgtcaccata
     9961 tccaatgatg aagacgcccc caccatcgag tttgaagaag ctgcacacca agtccgggaa
    10021 cctgcagggc cggatgccac tgcagttctg agcgtcaagg tcatccgcag aggcgatcaa
    10081 aacaggacct ctaagatccg atgcagcact cgagatggct ctgcccagtc tggtgtggat
    10141 tattacccca agagcagagt cctgaaattc agtcccggcg tggatcacat cttcttcaaa
    10201 gtcgagatcc tgtccaatga ggatcgagaa tggcacgaat ccttttctct agtccttggc
    10261 ccggacgatc cagtggaagc agtgcttggg gatgtgacta ctgctacagt gacaattcta
    10321 gaccaagagg cagcagggag tctcatattg ccggcaccac ccatcgtagt cactcttgct
    10381 gactacgatc atgtggaaga gctgtcaaag gaaggcgtca agaaagcccc atccccaggc
    10441 tacccgctag tttgtgtcac gccctgtgac ccccactacc ccaggtatgc tgtcatgaag
    10501 gagcgatgca gcgaggctgg tattaaccaa acgtctgtgc agttcagctg ggaggtggct
    10561 gcgcccaccg acggcaatgg ggctcggtct ccctttgaga ccatcacgga cagcacacca
    10621 ttcaccagcg tcaaccacaa ggtcctagac agcatttact tcagccggag gttccatgtg
    10681 cgatgtgtgg ccaaggctgt ggacaaggtg ggccatgtag ggaccccgtt gaggagcaat
    10741 gttgttacca ttggaaccga cagtgctatc tgccacaccc cagtagtggc tgggacagct
    10801 cgaggcttcc aggcacagtc cttcatcgcg accttgaagt acttggacgt caaacacaaa
    10861 gaacatccga acagaatcca catctccgtg cagatccctc accaggatgg gatgctgccc
    10921 ctaatctcga ccatgcccct acacaacctg cacttcctgt tgtcggaatc catttacaga
    10981 cagcagcacg tctgttccaa cctagtcacc gcccgggacc tgcgaggcct ctcagaggca
    11041 gggttcctgg atgacgcagg tctccatagt actgccctgg gccctggcta tgaccgtccc
    11101 ttccagtttg acccaagtgt acgggagccc aaaaccatcc agctgtacag acacctgaac
    11161 ctgaagagct gcgtgtggac ctttgatgca tactacgaca tgacagagct catcgatgtg
    11221 tgtgggggct ccgtgactgc tgacttccag gtgagagact ctgctcagtc gttcttgaca
    11281 gtgcacgtgc ctctctacgt gtcctacatc tacgtgacag cccccagggg ctgggcctcc
    11341 ttagagcacc acactgagat ggaattctct ttcttctatg acacagttct ctggagaaca
    11401 ggcatccaga cagacagtgt gctctctgca agacttcaga tactaagaat ctacattaga
    11461 gaggatggcc gtctcgtcat cgagttcaag acccatgcca aattcagagg acagtttgtg
    11521 atagaacacc acaccctccc agacgtgaag tctttcatat tgactccaga ccacctagga
    11581 ggaattcagt ttgacctgca gctcctgtgg agtgctcaga catttgattc tccacatcaa
    11641 ctctggcgag ccacgagctc ttacaacaga aaggactact caggggagta caccatctac
    11701 ctgatccctt gcaccgtgca gcccacacag ccatgggtgg acccaggaga gaagtctttg
    11761 gcctgcactg ctcatgcccc agaaaggttc ctgataccca tcgcgttcca acagaccaac
    11821 cgccctgtgc cggttgtgta ttcgctcaat actgagtttc agctctgcaa taacgagaag
    11881 gtattcttga tggatcccaa cacgtctgat atgtcgctgg cagaaatgga ttacaaagga
    11941 gctttttcca aaggtcagat cctttacggc cgagtccttt ggaatccaga gcaaaacctt
    12001 cattctgctt acaaactgca gctggagaaa gtctatcttt gtacgggcaa ggatggctac
    12061 gtgcctttct ttgaccctac ggggacaatc tacaatgaag ggccacagta cggatgcatt
    12121 cagccaaata aacacctgaa gcacagattc ctgctgctgg accgcagcca gccagaggtc
    12181 actgacaagt atttccatga tgtgcctttc gaggcccatt tcgcttctga gttgcctgat
    12241 ttccaggtgg tcagcagcat gccgggtgtg gatggattta ccctcaaagt agatgccctc
    12301 tataaggtgg aagcaggaca tcagtggtat ctccaagtga tctacatcat cagccctgac
    12361 agcatctcga ggcctcgggt ccagcgctct ctcactgcct ctctgaggcg ccaccaaagg
    12421 gacctggtgg atcccagcgg ctggctgtct ctcgatgact ccctcatcta cgacaacgaa
    12481 ggagaccagg tcaagaacgg caccaacatg aagtccctga acctggaact gcaggagccc
    12541 gtgatagctg cttccctgtc acaatccgga gcctctatcg gcagtgccct ggctgctctc
    12601 atgcttctcc tgctgctgtt tctggtggcc tgtttcatca ccaggaagtg ccagaagcaa
    12661 aagaagaaac agcctccgga ggacactctg gaggaatacc ccctgaatac caaggtggat
    12721 gtagccaaga aaaacacaga caagggggag aagaatgcca acagacagta ctgtaccgtg
    12781 cgcaacgtca acatactgag tgacagtgag gggtattata cgttcaaagg tgctaaagta
    12841 aaaaaactga acctggaagt cagagtccac aacaatttac aagatgggac ggaagtttaa
    12901 tgcgaagacc cgaggcgtat tttctttttt tttttttttc taaaatcctt tttataaaac
    12961 ggggagaaat actggtattt ttataatctt tcaagttaaa aaaaaaaaca aaacaaaaag
    13021 ggaacactag ctttgagcgg tggacagcac acatagcatg catcgactca caactgagct
    13081 acctcacgaa acagaaccac tgaggcacgt ccccctcccc cagagtgtca gagtagggtt
    13141 atgcctgcag gtccctgtaa cggtctcagt ggccacacag ggcgaccctg tgaggctgac
    13201 tgcagaagcg ttttagaact aggacagata ctggacaatt agcttcgctg atcagatcga
    13261 gaaagctcca tgggcagcag ttatctgaga gtacaaagcc tttgcttcct tcccctgccc
    13321 aactttcttc tctgtgggct tttctggact tctagacaca gaatacagaa ggctgacaca
    13381 cagactccat taacgattct aatcagcaca gcttagacaa tctgtgcact gtttccactt
    13441 actgtcctgt gcgccctggc cacctctgag tgcatttggc ttttctagag ccctttttga
    13501 acggggatcg caacatgctt taccctggag tgcttggagc gatgaggagt gctgcaaagt
    13561 accacagcct ttgcatgcca gagataccca cttcccccgg ctttctgtgg tttatcaatg
    13621 caatgggagc ttgtgtgttt ggggttttta attttgttaa tttttttttt tgtagagtaa
    13681 gtgaatcatt tgagtaagca aatttcctag aggtcggaat gaagccagag ttagcagata
    13741 cacatggggc ctctttgctg tgtgtcacac agcagataga ggtaccgtcc ctggtgtgat
    13801 attcagggga cttctctctg ggggttcttt tctggtagct caggcactta atttctccca
    13861 catcagtaca cgacaaccca catcacgtgt ggcttttaca tagcatagtg ttcagatatc
    13921 gacttgaata ttctgtgtgg tgtgcacaca acttgccttt gttttctttt tgtttctacc
    13981 ttattggtaa aatctgacgc gtgcacgtac actgtgtttt tacccagagg cacaattccg
    14041 ttagccagaa gcaaatgtta gtccagtgca tggcacgtcc tatcagtgag taaatcacag
    14101 agcatcctcc ttgtgtagta tcggtgtgga aatgacccaa actctttgag aacattccag
    14161 actcgtacta aaatctagaa agaatgaacc gtgaaaactt tacaggcaac tctgcagacc
    14221 cggagctcga gagcagagcc tgtgtgaacc acagctcttc attctacagc agtgccttgc
    14281 acattacaag catgccagaa gtgtttgttg agtgaatgcg tggacggcgt gccgagtgaa
    14341 tgacagggag taaactgaga aagaagaggt gagactgtgt gctatgactt aacagggcgt
    14401 gtagaaacgg ccgctgttgt agtatttgga ttgtgaaata gtccttcaac tgagggaagg
    14461 gggggggggg gaagcacact tttaggtggg tatgactgga ggtgtttctg aggagtcagg
    14521 aacagaaatg attgtagtaa tgcatgagct gcatattggc gtccagaatg ggagatttgg
    14581 tgggaatccg gtttcacatt tcgagagtaa tgcggtgtct tcaggacagg agaggtcagt
    14641 tgagcccaga aattcctggc tggtcaggtg ctacttcaga ccagctagca taattcaagg
    14701 cagaaattgt ggaatcgctt caagaatcta gaatcgatac ccatcccgtg cagcagagct
    14761 catgttgccc tgaatctcca ggacaacaga gagggctaga gcacagacag ggagccaatc
    14821 atttgtagag cagcttccca ttggcccatt cctggtcaca cctcccgctg ccaggatgtt
    14881 cacacattag agcgcgggct ttcggtggcc tccacagaga cacaccttgc atacctgtga
    14941 agaggtggca gagcctggtg agggaaggga ggctgaatcc agaggccttt gtgtacaggg
    15001 tgggcagtga aaagacacga gcctgtgcgg aactggtcat ggtgaactct tggccaaaga
    15061 acagcccctg aaatagccct gcctcccagc ctcgccccta cagacacttt attagaaggc
    15121 agcctcctct cgtggatgcc cacttctgaa gcaggaagcg ttaggagacg tagtgctgag
    15181 atttgccttt tgagcgattt cgaattgttc atttcattta cattttgtac ttcctctttg
    15241 ggattggata attttggtga ctagtgtgga ttctatgtcc gtgaaagctt tgctttcggt
    15301 gtttcttact tctccactaa tgccttgtgt gtgtttttgc taacctttta gatcatacct
    15361 tcaggtgaga agaacagaaa aaccctcagc ggggttgctc cttgctgcca ggtgctggct
    15421 gtgaaggtca aaagaaataa ttgtctgcac cggccttgcc tgtaccaagg tctttggaaa
    15481 acccctgcgg gttcctattg ttggatggga aattgtgtgg aaaaatgttt ccacaatctt
    15541 aacaataagc gttctcggtc tcctgtaggt ttttgttatt cctggttctc acctgctcag
    15601 actgaggaaa acatttgtgg tgctgtcaac ctgtgttctt gaccctcaga tgattttttt
    15661 ttttgtattt tcagtatgaa tttgtgtgtt acaaatttct gatttcgcca atagcatatg
    15721 ccactatata aatttgtatc aataataaat gacagcctgg ttgtcgtttg tttgcttga
//
