LOCUS       NM_199494               3439 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus fucose-1-phosphate guanylyltransferase (Fpgt),
            transcript variant 1, mRNA.
ACCESSION   NM_199494 XM_227789
VERSION     NM_199494.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3439)
  AUTHORS   Pastuszak,I., Ketchum,C., Hermanson,G., Sjoberg,E.J., Drake,R. and
            Elbein,A.D.
  TITLE     GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and
            properties of the enzyme
  JOURNAL   J Biol Chem 273 (46), 30165-30174 (1998)
   PUBMED   9804772
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 1, 2020 this sequence version replaced NM_199494.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168244.1, SRR26643296.8022.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                JAXUCZ010000002.1  246778766-246778848 c
            84-251              JAXUCZ010000002.1  246776555-246776722 c
            252-344             JAXUCZ010000002.1  246775321-246775413 c
            345-3439            JAXUCZ010000002.1  246770167-246773261 c
FEATURES             Location/Qualifiers
     source          1..3439
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..3439
                     /gene="Fpgt"
                     /note="fucose-1-phosphate guanylyltransferase"
                     /db_xref="GeneID:310935"
                     /db_xref="RGD:735121"
     exon            1..83
                     /gene="Fpgt"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1798
                     /gene="Fpgt"
                     /EC_number="2.7.7.30"
                     /note="isoform 1 is encoded by transcript variant 1;
                     gdp-L-fucose pyrophosphorylase"
                     /codon_start=1
                     /product="fucose-1-phosphate guanylyltransferase isoform
                     1"
                     /protein_id="NP_955788.2"
                     /db_xref="GeneID:310935"
                     /db_xref="RGD:735121"
                     /translation="METLREATLRKLRRFSELRGKPVAAGEFWDVVAITAADEKQELA
                     YKQQLSEKLRRKELPLGVQYHVFPDPAGTKIGNGGSTLCSLQCLESLYGDEWNSFKVL
                     LIHSGGYSQRLPNASALGKIFTALPLGEPIYQMLELKLAMYVDFPSHMKPGVLVTCAD
                     DIELYSVGDCQYIAFDQPGFTALAHPSSLAVGTTHGVFVLHSASSLQHGDLEYRQCHR
                     FLHKPTIENMHQFNAVQRQGSFAQQDFPGGDTACLPLHTEYVYTDSLFYMDHKSAKKL
                     LDFYKSVDQLNCEIDAYGDFLQALGPGATAEYTRNTSHVTKEDSQLLDMRQKIFHLLK
                     GTPLNVVVLNNSRFYHIGTTQEYLLHFTSDSTLRSELGLQSIAFSVSPSVPESSNETA
                     CIIHSILDSGCCVAPGSVVEYSRLGPEVSIGENCIVSSSVLANTAVPAYSFVCSLSVR
                     TNGLLEYSTMVFSVQDNLKGSVKTLEDIKALQFFGVCFLSCLDIWNLKATEKLFSGSK
                     RNLSLWTARIFPVCPSLSESVTASLGMLSAVRSHSPFSLSNFKLMSIQEMLVYKDVQD
                     MLAYREQIFLEINSNKKQSDLEKS"
     exon            84..251
                     /gene="Fpgt"
                     /inference="alignment:Splign:2.1.0"
     exon            252..344
                     /gene="Fpgt"
                     /inference="alignment:Splign:2.1.0"
     exon            345..3439
                     /gene="Fpgt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctaagtgggc tcccggaagt cggccatgga gactctccgg gaagccaccc tgcggaaact
       61 gcgcagattt tcggagctga gaggcaaacc tgtggcagct ggagaattct gggatgtggt
      121 tgcaataaca gcagccgatg aaaagcagga gctcgcttac aagcagcagt tgtcagagaa
      181 gctgagaaga aaggaattgc ctcttggagt tcaataccat gtttttcctg atcctgctgg
      241 gaccaaaatt ggaaatggag gatcgacact ttgttccctt cagtgcctag aaagcctcta
      301 tggagatgaa tggaattctt tcaaggtcct gttaattcac tccggtggct acagtcaacg
      361 ccttcccaat gcaagtgctt taggaaagat cttcacagcc ttaccacttg gtgaacccat
      421 ctatcagatg ttggagttaa aactagccat gtacgtggat ttcccctcac acatgaagcc
      481 tggagtcttg gtcacctgtg cagatgacat tgaactgtac agtgttgggg actgtcagta
      541 cattgccttt gaccagcctg gctttactgc cttagcccat ccttccagtc tggctgtagg
      601 caccacacac ggagtatttg tcttgcactc tgccagttcc ttacaacatg gtgaccttga
      661 gtacagacaa tgccaccgtt tcctccacaa gcccaccatt gaaaacatgc atcagtttaa
      721 tgctgtgcaa agacaaggaa gctttgctca acaggacttc cctggaggtg acaccgcgtg
      781 tcttccattg cacactgagt atgtctacac agatagcctg ttttacatgg accacaaatc
      841 ggccaaaaag ttacttgatt tctataaaag tgtagaccaa ctgaactgtg aaatagatgc
      901 ctatggtgac tttctgcagg cactggggcc tggagcaact gcagagtata ccaggaacac
      961 atcacatgtc actaaagaag actcccagtt gttggacatg aggcagaaaa tattccacct
     1021 cctcaagggg acaccactga atgttgttgt tcttaataac tccagatttt atcacattgg
     1081 aacaacacaa gaatatctgc ttcatttcac gtctgatagt acgttaaggt cagagctagg
     1141 cttacagtcc atagctttca gtgtctctcc aagtgtccct gaatcctcca atgaaacagc
     1201 ctgtatcatt cacagtatac tggattcagg atgctgtgtg gcccctggct cagttgtaga
     1261 gtattctaga ctggggcctg aggtgtccat tggggaaaac tgcattgtca gcagctctgt
     1321 cctagcaaac actgctgtac cggcatattc ttttgtgtgt tctctaagtg tgaggacaaa
     1381 tggactcttg gaatattcta ccatggtgtt tagtgtgcag gacaacttga aaggcagtgt
     1441 taaaaccctg gaagatataa aggcacttca gttctttgga gtctgtttct tgtcttgttt
     1501 agacatctgg aaccttaaag ctacagagaa actgttctct ggaagtaaga ggaacctgag
     1561 cctgtggact gcacggattt tccctgtctg tccttctctg agtgagtcag ttacagcatc
     1621 ccttgggatg ttaagtgctg taaggagcca ttcaccattc agcctaagca actttaagct
     1681 gatgtccatc caggaaatgc ttgtctacaa agatgtacaa gacatgctag cttataggga
     1741 gcaaattttt ctagaaatta attcaaataa aaaacaatct gatttagaga aatcttaaat
     1801 tgaacatatt ttgtctgtaa acaaaattga aaatgcagat atttttctat agacctctga
     1861 ctttttgttt agtaaatcaa tataataaaa gttatattaa taaaaagcgt tgtagcttgg
     1921 taatgaataa ggtatggctg agcacttcag ctggaaggac attctgggac taaagtcagg
     1981 aaagcgatgc tgtttcagat gtttgcatca tcttaatttt gctttttggg tgaaggtcca
     2041 tttacgggca ctgtttggtt cacagaataa atacttctga tctatgggat gattttctaa
     2101 acataccttt acagttttcc tatcttcttt tggaatttgg accaataaag ttctaggtga
     2161 tattgatgat tatattactt tacttctcac agtgagacac atctaacaat acattgttag
     2221 aaattcctaa aagaaatatc attatttgag gttttctttc aagatttttt tctagtttta
     2281 tgtgtacgag tgctttactt gcatgtatgt ttgtgcaccg catgcttgct ctgcccatag
     2341 aagctaaaac agctgttctc aacctgtggg tggtgacctt tttggggatg aaacaatctt
     2401 ttgaggggta acctaagacc actggaaaat aaaatattcg cattgcgatt tataacagga
     2461 aaattacagt taagaagtag caacaaaagt aattttacag tttgggtcac cacagcctta
     2521 ggaactgttt ttaaaggatg gcagcatcag gaaggttgag aaccactggt ctagaagaag
     2581 gcattggatc tgttggaatc agttatagat ggttacaacc tccatattgt ttagtctgca
     2641 agtcaacttt agtcctatga aagtgctata aaatgatgtt tgtgcctcac tgatcttgcc
     2701 aaaatgagat taaaatgtac gtgtgtgtta ttcttataca cttgaacatg gggtgccata
     2761 ttttataaac tacatcactg atctattgca ctggaaaatg catacacaca gtatgcggtt
     2821 gtctgctcag gaggtggtag gaatagttga gagccagtgc tcactcagcg tggacattac
     2881 tttatcctct cctaattaat ccttcaacaa gtctcttgac aatgagcatt tgccttacat
     2941 cgttttgtgt ccatagtggt agtgatgctg tggacaagca attggcccaa agacaggaaa
     3001 ttccaatagg aaatctgagg taatactcag atcataacag gtagaattcc tggttatatg
     3061 catctatttt gaaataaaca cattagtgga atgtctttag gttgaacttg aatcgaggcg
     3121 agacttatac ttaaggaaac tgtaatatct actgtgacat attacttata tgtaagtttt
     3181 cataaaaata tatgataaac aagatatcta tcaaacccct ctttattatt tataatgaat
     3241 atgtatttaa ccttttgagg ttctagacaa taaagcaaag tatacgtgat gatatttgac
     3301 agtgattgat ttacagggat ttcaaaggat gttgaatgct attaaatgtt caaaactaaa
     3361 gtcccatcaa gtattagaat tatgattgca tgttccaaaa aaatctatta ttaataaaga
     3421 ataccatcac ttccttgca
//
