LOCUS       NM_001419933            3897 bp    mRNA    linear   ROD 13-JUN-2023
DEFINITION  Rattus norvegicus FAD-dependent oxidoreductase domain containing 1
            (Foxred1), mRNA.
ACCESSION   NM_001419933 XR_086322
VERSION     NM_001419933.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3897)
  AUTHORS   Formosa LE, Mimaki M, Frazier AE, McKenzie M, Stait TL, Thorburn
            DR, Stroud DA and Ryan MT.
  TITLE     Characterization of mitochondrial FOXRED1 in the assembly of
            respiratory chain complex I
  JOURNAL   Hum Mol Genet 24 (10), 2952-2965 (2015)
   PUBMED   25678554
REFERENCE   2  (bases 1 to 3897)
  AUTHORS   Fassone E, Duncan AJ, Taanman JW, Pagnamenta AT, Sadowski MI,
            Holand T, Qasim W, Rutland P, Calvo SE, Mootha VK, Bitner-Glindzicz
            M and Rahman S.
  TITLE     FOXRED1, encoding an FAD-dependent oxidoreductase
            complex-I-specific molecular chaperone, is mutated in
            infantile-onset mitochondrial encephalopathy
  JOURNAL   Hum Mol Genet 19 (24), 4837-4847 (2010)
   PUBMED   20858599
  REMARK    Erratum:[Hum Mol Genet. 2015 Jul 15;24(14):4183. PMID: 26022995]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000190.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001419933.2.
            
            On Apr 21, 2023 this sequence version replaced XR_086322.6.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            inferred exon combination          :: based on alignments, homology
            RefSeq Select criteria             :: based on expression, longest
                                                  protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               JACYVU010000190.1  18364196-18364337   c
            143-363             JACYVU010000190.1  18363223-18363443   c
            364-477             JACYVU010000190.1  18362308-18362421   c
            478-596             JACYVU010000190.1  18361928-18362046   c
            597-691             JACYVU010000190.1  18360838-18360932   c
            692-793             JACYVU010000190.1  18360440-18360541   c
            794-870             JACYVU010000190.1  18358967-18359043   c
            871-1031            JACYVU010000190.1  18358611-18358771   c
            1032-1161           JACYVU010000190.1  18358339-18358468   c
            1162-1266           JACYVU010000190.1  18358050-18358154   c
            1267-3897           JACYVU010000190.1  18355201-18357831   c
FEATURES             Location/Qualifiers
     source          1..3897
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q21"
     gene            1..3897
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /note="FAD-dependent oxidoreductase domain containing 1"
                     /db_xref="GeneID:315547"
                     /db_xref="RGD:1311785"
     exon            1..142
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..1521
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /codon_start=1
                     /product="FAD-dependent oxidoreductase domain-containing
                     protein 1"
                     /protein_id="NP_001406862.1"
                     /db_xref="GeneID:315547"
                     /db_xref="RGD:1311785"
                     /translation="MFRKVLRLGLCPGLPTRGLRTRTGGFTLDWDTKVSDFKKKIESI
                     LPGKQCEMVYDTSHLPPEQSDVVIIGGGILGLSVAFWLKKLESRRGAMQVLVVEQDHT
                     YSRASSTGPSVGGIWQQFSVPENVQLSLFSINFLRNINEYLAVVDAPPVELRFNPSGC
                     LLLASEKDAATLESNVRMQRQEGAKVCLMSPEQMQNKFPWMNAEGVALASYGLENEGW
                     FDAWSLLQGLRRKVQSMGVFFCQGEVTRFITSSNQMETPTGEQVVLRRINNVHVKMDK
                     SLEYQPVECAVVVNAAGAWSGQIAELAGIGKGLPGTLQGTKLPVEPRKRYVHLWHCPQ
                     GPGLETPLVADISGVYFRREGLGSNYLGGCSPTEEEEPDPTNLEVDHDFFQNKVWPHL
                     VQRVPSFKTLKVQSAWAGYYDYNTFDQNGVVGPHPLVVNMYFATGFSGRGLQHAPGIG
                     RAVAEMILEGHFKTIDMSPFLFTRFYLGEKLQEHNIL"
     exon            143..363
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            364..477
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            478..596
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            597..691
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            692..793
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            794..870
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1031
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1161
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1266
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..3897
                     /gene="Foxred1"
                     /gene_synonym="RGD1311785"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagtcggcc tgagcggcag gcacctcaag ctggaagaag ccgggctctg taaggccatg
       61 tttcgcaaag tgctgcgtct tggcctgtgc ccgggcctcc ctacccgggg gctacgcaca
      121 cgcacaggag gctttactct ggactgggat acaaaggtgt ctgactttaa gaagaagatt
      181 gagtctatcc tgccgggaaa gcaatgtgaa atggtgtatg acaccagcca cctgccccca
      241 gaacagtcgg atgtggtcat catcggcggt gggattcttg gtctgtctgt ggccttttgg
      301 ctgaagaagc tggagagtag acgaggtgcc atgcaggtgc tggttgtgga acaggaccac
      361 acgtattcac gggcttcctc cacagggcct tctgtgggcg ggatttggca gcagttttct
      421 gttcccgaga atgtccaact ctcactcttt tcaatcaact ttctacggaa cataaatgag
      481 tacctagctg tggtggacgc ccctcctgtg gaacttcggt tcaacccctc aggctgtctc
      541 ttgctagctt cagaaaagga tgctgccacc ttggaaagca atgtgagaat gcaaaggcag
      601 gaaggagcca aggtctgtct gatgtctcct gagcagatgc agaacaagtt tccctggatg
      661 aacgcagagg gagtggctct ggcatcttat gggttggaga atgaaggttg gtttgatgcc
      721 tggtctttgc tccagggtct tcgtcgaaag gtccagtcaa tgggagtctt tttctgtcag
      781 ggagaggtga cacgtttcat cacttcatct aaccaaatgg agactccaac tggggaacag
      841 gtagtcttga gaaggatcaa caatgtccac gtgaaaatgg acaagagcct ggagtatcag
      901 ccagtggaat gtgctgtagt ggtcaatgcc gcaggagcct ggtctggaca aattgcagag
      961 ttggctggta ttggaaaggg acttcctggc accctccagg gcaccaagct acctgtggag
     1021 ccaaggaaaa ggtatgtgca cttatggcac tgcccgcagg gaccaggtct ggagacaccg
     1081 ttggttgcag acatcagtgg agtgtatttc cgacgggaag gattgggcag caactaccta
     1141 gggggctgta gccctactga ggaagaagaa ccagacccaa caaatctgga agtggaccat
     1201 gacttcttcc agaacaaagt gtggccccat ttggtccaga gggtgccatc ttttaagact
     1261 ctgaaggtac agagtgcctg ggctggctat tatgactaca atacttttga ccagaatggc
     1321 gtggtgggcc cccacccact agttgtcaac atgtactttg ctacgggctt cagtggtcgt
     1381 ggacttcagc atgcacctgg catcggtcga gctgtggcag aaatgatact agagggtcac
     1441 tttaagacca tcgatatgag ccccttcctc ttcacccgct tttacttagg agagaagtta
     1501 caggagcaca atattctctg aatgtgaaac tcttctctgg gccttgcctt gtctcatgtt
     1561 ggctttggtc actgcccaag tctccccaga actgtgccag gaatacatcc ctttcctcac
     1621 cgtcctttaa accaggcctc ttcccagtgt ctctgaaatg gaataaacaa aggcacagag
     1681 accaggccaa tggaaagtaa cacagtggga ccctagggct gattgtagcc taggctgatt
     1741 cactacccaa acagttcagc tggcatcctg ggcatggtgc ccaggactgg cctccttcct
     1801 ggtgctgata cagagaaatc tgaccagagc caaggcacag agcattccag gatagcctga
     1861 cccaaattta ttgacttgtc taataactta ttcttcaatc aacatatgta tatgattaac
     1921 cccttctctc tggccttata ttcttcccac ttttcttctc atagtagaag catttgaagt
     1981 attgtgccat taaaaaggca gctttagggc tgaagagatg gttaagaacc ctgactgctc
     2041 ttccagaggc cctgagttca attcctagca agcacatggt ggctcacaac catctgtaat
     2101 gggatctgat gccctcatct agtctgtctg aagacagtac aatactcatg tatttaaaaa
     2161 aaaaaaaaaa aaaaaaaaga caacctcatc ctcttgagag tatttcttaa attctctgtg
     2221 ggagacatct tgtttgcaag cttgtatcct gttacctgag ttctacggca accatggttc
     2281 tagcgaatga aatggagtca ttcatctagt caacttctat aaagctccag cttctggcta
     2341 ctgacattca gtctatagca ggattcaaag tggctttctg agtggatcat ggagctttgt
     2401 ggggaaaaag tagccagcat ctgaagagcc acactgagaa gcttggattt catctcagca
     2461 gagacccagc agaagatttt taaagatgga agcaatatga tcagatcttc cttttaggcg
     2521 gcagattgct tgcttagcat gtggatggcc ccgggtttga tactcagcac caacagcaga
     2581 gaggatctgg gggaagtcac tggcttcctt gtagagaata gagtcagaga gcaaagcagg
     2641 aaagcaggct ctagataaag actgtttcag tctacttagc agtcatggtg ggaaacacat
     2701 ggaatgatgt gacaatgcca atgtgacatg gagtcagtat ttcccggctt tctggctaaa
     2761 cagctaaaca agtaccatgc ttcttaccaa aatgacagag ggaacagcaa aatgagtagt
     2821 ctgatgtggg acaaactgaa aggaaagtgc ctgtgggagg tgtgatgggt gattgcacta
     2881 gttgggtgga caggtgacag aacagcatca ccaaaggaga gcaaaatgta gggacaacta
     2941 aaaagctgga gtatccactg acatttagag aaaacagatg aacgctgaag gactgaccca
     3001 tgaggcagga gaaaatccag tgatacggaa tcatgaagac caagaagtag gcaccagaat
     3061 gaaatgtccc atgccagctg ggctcagcac ctagcactca ctggtgacca gggaatgcaa
     3121 tctaaggcac atagtagagt agaaaatctt gggaaaatgg ctccttcatc agaagtcctt
     3181 tggagtaaat aaaaagtaaa agaggtagat atcatatagg ggaggggaca ggagaagaga
     3241 tgggccagct gggagtataa agcctgtgtg gtttgaagag cgccaggaat gaggcagtaa
     3301 gcaaaagaaa agtcaccaga agataatgct gaaatatcat gtcaggaaca gcgtggacag
     3361 gctttaggtt aaagaggaaa aatcagagac ttggattata aattagccct ggattataga
     3421 ggtgccctgt agcagaattt taacagaatg tttgtatctg ccatgaatct ggagtaatgg
     3481 cacctaagct ttgaagtagc ttttgtcagt gattgttatc tgagattttt atggggttat
     3541 tcctttgaag gttttttcag cctttgcata tcatagtcag gagataggtc tggcaaaccg
     3601 ggacatctcc catggttgag aattgcttag gtgattgtag gatgatgtca tacaggtgaa
     3661 ggcaggtaca agatagaatg aggcctgtca ttggacgaga aggaaggatg ggcgggagaa
     3721 aagttttaga gagaggagac tggaaccaga ggagagaagc agctaggaga aaatggaggt
     3781 ggatgttaag atccctctct gtacacttac aggttgttat gaatattctt aagggatgta
     3841 tatgtccagg gctttgtatg tttaggtggg caattatatc ttatcaattg gatcaga
//
