LOCUS       NM_001037219            2487 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus forkhead box K1 (Foxk1), mRNA.
ACCESSION   NM_001037219 XM_221936
VERSION     NM_001037219.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2487)
  AUTHORS   Sukonina,V., Ma,H., Zhang,W., Bartesaghi,S., Subhash,S.,
            Heglind,M., Foyn,H., Betz,M.J., Nilsson,D., Lidell,M.E.,
            Naumann,J., Haufs-Brusberg,S., Palmgren,H., Mondal,T., Beg,M.,
            Jedrychowski,M.P., Tasken,K., Pfeifer,A., Peng,X.R., Kanduri,C. and
            Enerback,S.
  TITLE     FOXK1 and FOXK2 regulate aerobic glycolysis
  JOURNAL   Nature 566 (7743), 279-283 (2019)
   PUBMED   30700909
REFERENCE   2  (bases 1 to 2487)
  AUTHORS   He,L., Gomes,A.P., Wang,X., Yoon,S.O., Lee,G., Nagiec,M.J., Cho,S.,
            Chavez,A., Islam,T., Yu,Y., Asara,J.M., Kim,B.Y. and Blenis,J.
  TITLE     mTORC1 Promotes Metabolic Reprogramming by the Suppression of
            GSK3-Dependent Foxk1 Phosphorylation
  JOURNAL   Mol Cell 70 (5), 949-960 (2018)
   PUBMED   29861159
REFERENCE   3  (bases 1 to 2487)
  AUTHORS   Bowman,C.J., Ayer,D.E. and Dynlacht,B.D.
  TITLE     Foxk proteins repress the initiation of starvation-induced atrophy
            and autophagy programs
  JOURNAL   Nat Cell Biol 16 (12), 1202-1214 (2014)
   PUBMED   25402684
REFERENCE   4  (bases 1 to 2487)
  AUTHORS   Freddie,C.T., Ji,Z., Marais,A. and Sharrocks,A.D.
  TITLE     Functional interactions between the Forkhead transcription factor
            FOXK1 and the MADS-box protein SRF
  JOURNAL   Nucleic Acids Res 35 (15), 5203-5212 (2007)
   PUBMED   17670796
REFERENCE   5  (bases 1 to 2487)
  AUTHORS   Yang,Q., Kong,Y., Rothermel,B., Garry,D.J., Bassel-Duby,R. and
            Williams,R.S.
  TITLE     The winged-helix/forkhead protein myocyte nuclear factor beta
            (MNF-beta) forms a co-repressor complex with mammalian sin3B
  JOURNAL   Biochem J 345 Pt 2 (Pt 2), 335-343 (2000)
   PUBMED   10620510
REFERENCE   6  (bases 1 to 2487)
  AUTHORS   Yang,Q., Bassel-Duby,R. and Williams,R.S.
  TITLE     Transient expression of a winged-helix protein, MNF-beta, during
            myogenesis
  JOURNAL   Mol Cell Biol 17 (9), 5236-5243 (1997)
   PUBMED   9271401
REFERENCE   7  (bases 1 to 2487)
  AUTHORS   Bassel-Duby,R., Hernandez,M.D., Yang,Q., Rochelle,J.M., Seldin,M.F.
            and Williams,R.S.
  TITLE     Myocyte nuclear factor, a novel winged-helix transcription factor
            under both developmental and neural regulation in striated myocytes
  JOURNAL   Mol Cell Biol 14 (7), 4596-4605 (1994)
   PUBMED   8007964
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Feb 16, 2008 this sequence version replaced NM_001037219.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.83935.1,
                                           SRR21887622.1368512.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-545               JAXUCZ010000012.1  17288020-17288564   c
            546-731             JAXUCZ010000012.1  17251621-17251806   c
            732-888             JAXUCZ010000012.1  17238431-17238587   c
            889-1035            JAXUCZ010000012.1  17236898-17237044   c
            1036-1229           JAXUCZ010000012.1  17235174-17235367   c
            1230-1396           JAXUCZ010000012.1  17232831-17232997   c
            1397-1681           JAXUCZ010000012.1  17232463-17232747   c
            1682-1906           JAXUCZ010000012.1  17230941-17231165   c
            1907-2487           JAXUCZ010000012.1  17229430-17230010   c
FEATURES             Location/Qualifiers
     source          1..2487
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2487
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /note="forkhead box K1"
                     /db_xref="GeneID:304298"
                     /db_xref="RGD:1309643"
     exon            1..545
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..2187
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /codon_start=1
                     /product="forkhead box protein K1"
                     /protein_id="NP_001032296.2"
                     /db_xref="GeneID:304298"
                     /db_xref="RGD:1309643"
                     /translation="MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPATASPPPPA
                     QPPPGPPALPAVPGPEPVPSTAATATATAPALVAAAAASVRQSPGPALARLEGREFEF
                     LMRQPSVTIGRNSSQGSVDLNMGLSSFISRRHLQLSFQEPHFYLRCLGKNGVFVDGAF
                     QRRGAPALQLPQQCTFRFPSTAIKIQFTSLYHKEEAPASPLRPLYPQISPLKIHIPEP
                     DLRSLVSPIPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQ
                     QADTSGGDSPKDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKG
                     WQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFR
                     TPFGPLSSRSAPASPTHPGLMSPRSSGLQTPECLSREGSPIPHDPDLGSKLASVPEYR
                     YSQSAPGSPVSAQPVIMAVPPRPSNLVAKPVAYMPASIVTSQQPSGHAIHVVQQAPTV
                     TMVRVVTTSANSANGYILASQGSTATSHDTAGTAVLDLGNEARGLEEKPTIAFATIPA
                     ASRVIQTVASQMAPGVPGHTVTILQPATPVTIGQHHLPVRAVTQNGKHAVPTNNLTGN
                     AYALTSPLQLLAAQASSSTPVVITRVCEVGPEEPTAAVSVAASAAPTPAISTTTSASS
                     SGEPELKRSRVEEPSGTATTQPTAMAATGPQGPGTGE"
     exon            546..731
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            732..888
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            889..1035
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1229
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1396
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1681
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1906
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2487
                     /gene="Foxk1"
                     /gene_synonym="RGD1309643"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accggagccg ctcggagctg cgcgaacatg gccgaagtcg gcgaggacag cggcgcccgc
       61 gccctgctgg cgctgcgctc ggctccctgc agccccgtgc tatgtgccgc ggccgcggcc
      121 gccgccttcc cggccacagc gtccccgccg ccgccggcgc aacctccgcc cgggccgccc
      181 gcgctgcccg ccgtgccggg ccccgagccg gtgccctcca ccgccgccac tgccaccgcc
      241 accgcgcccg ccctggtggc cgccgccgct gcctccgtgc gccagagccc cgggccggct
      301 ctggcgcgcc tggagggtcg ggagttcgag tttctgatgc ggcagcccag cgtcaccatc
      361 ggccgcaatt cgtctcaggg ctcggtggac ctgaacatgg gcctgtcgag cttcatttcc
      421 cggcgccacc tgcagctcag cttccaggag cctcacttct atcttcgctg tctcggcaag
      481 aacggcgtct tcgtggacgg ggccttccag aggcgcggag cgcccgccct gcagctgccc
      541 caacaatgca ccttccggtt cccgagcacg gccatcaaga tccagttcac atccctgtac
      601 cataaggagg aggccccagc atcccccctg cggccactct acccgcagat ctccccactg
      661 aagatccaca ttccggagcc ggatctccgg agccttgtca gccccatccc ttcccctacc
      721 ggcaccatca gtgtccccaa ctcctgtcca gcaagtcctc gaggggctgg gtcgtccagt
      781 taccgcttcg tccagaatgt gacctctgac cttcagctgg ccgcagagtt cgccgcgaag
      841 gcagcctccg agcagcaggc agacacgtct ggtggggaca gccccaagga cgagtcgaag
      901 ccaccgtact cctatgcaca gctgatcgtg caagccatct cctcggccca ggacaggcag
      961 ctaacactaa gtggcatcta cgcccacatc accaaacatt acccttacta caggactgcc
     1021 gacaagggct ggcagaactc tatccgacac aacctctctc ttaaccgcta cttcatcaaa
     1081 gtccctcggt cccaggagga gcctgggaag ggctcctttt ggcgaataga ccctgcctcc
     1141 gaagccaagc tcgtggaaca agcgttccga aagcggaggc agagaggcgt ctcctgcttc
     1201 cgcaccccct ttgggcctct gtcctcacgg agtgctccag cttcacccac ccaccctgga
     1261 ctgatgtccc ctcgttccag tggcctgcag accccagagt gcctgtctcg agagggctcc
     1321 cccattccac atgatcccga cttggggtca aagttagcct ctgttccaga gtaccgctat
     1381 tcccagagtg ccccaggctc ccctgtcagc gcccagccgg tgattatggc tgtccctccc
     1441 cgaccttcca acttagtggc taagcctgtt gcctacatgc cagcttccat agtgacctca
     1501 cagcagccct caggccacgc catccacgtg gtccagcagg ctcccaccgt caccatggtg
     1561 agggtggtta ccacctctgc caactcagcc aacgggtaca tcctggcgag ccagggctcg
     1621 accgcgacct cccacgacac cgcaggcaca gccgtgctgg acctgggcaa tgaggctaga
     1681 ggtttggaag agaagcccac catagcattt gccacaatcc ctgcagctag ccgagttatc
     1741 cagacggtcg ccagccagat ggccccagga gtccctggac acacagtcac catccttcag
     1801 ccggctacac cagtgactat cgggcagcac caccttccag tccgggctgt cactcagaat
     1861 gggaagcatg ctgtacccac gaataacttg actggcaatg cttatgccct caccagcccc
     1921 ttgcagctcc tggcagccca ggcgagttca tccacgccag tggtcatcac ccgggtgtgc
     1981 gaggtagggc ctgaggagcc aacagcagcc gtctccgtgg cagctagtgc tgcgccgacc
     2041 ccagccatct ccactaccac atctgcctct tccagcgggg agcccgagct caagaggtcc
     2101 cgggtagagg agcccagtgg gacagccacc acacagccca cagctatggc agccaccggc
     2161 cctcagggcc cagggaccgg cgagtgaatg tcacctacag gaaagtggag tgaaactccc
     2221 gccgcaggag ccctagtggc cagcagctgc attcaaggac cgagtcgaaa agctcacaac
     2281 tgcctgcagc ccccgtgcag gtggccgccg cactcggaca atttcctttt tatctctgtc
     2341 ctcccatggt ttgaaacaaa cacataaacg agttcagaca acttgattgt atgaatctgg
     2401 gggttctgtg tgtttattta cccctctctc atgccatcac ctctccccag ctcttggggg
     2461 agaaggtcta gcccacctcc tcaggaa
//
