LOCUS       NM_012560               2815 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus forkhead box G1 (Foxg1), mRNA.
ACCESSION   NM_012560
VERSION     NM_012560.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2815)
  AUTHORS   He,Z.H., Zou,S.Y., Li,M., Liao,F.L., Wu,X., Sun,H.Y., Zhao,X.Y.,
            Hu,Y.J., Li,D., Xu,X.X., Chen,S., Sun,Y., Chai,R.J. and Kong,W.J.
  TITLE     The nuclear transcription factor FoxG1 affects the sensitivity of
            mimetic aging hair cells to inflammation by regulating autophagy
            pathways
  JOURNAL   Redox Biol 28, 101364 (2020)
   PUBMED   31731101
  REMARK    GeneRIF: The nuclear transcription factor FoxG1 affects the
            sensitivity of mimetic aging hair cells to inflammation by
            regulating autophagy pathways.
REFERENCE   2  (bases 1 to 2815)
  AUTHORS   Jolma,A., Yan,J., Whitington,T., Toivonen,J., Nitta,K.R.,
            Rastas,P., Morgunova,E., Enge,M., Taipale,M., Wei,G., Palin,K.,
            Vaquerizas,J.M., Vincentelli,R., Luscombe,N.M., Hughes,T.R.,
            Lemaire,P., Ukkonen,E., Kivioja,T. and Taipale,J.
  TITLE     DNA-binding specificities of human transcription factors
  JOURNAL   Cell 152 (1-2), 327-339 (2013)
   PUBMED   23332764
REFERENCE   3  (bases 1 to 2815)
  AUTHORS   Miyoshi,G. and Fishell,G.
  TITLE     Dynamic FoxG1 expression coordinates the integration of multipolar
            pyramidal neuron precursors into the cortical plate
  JOURNAL   Neuron 74 (6), 1045-1058 (2012)
   PUBMED   22726835
REFERENCE   4  (bases 1 to 2815)
  AUTHORS   Dastidar,S.G., Narayanan,S., Stifani,S. and D'Mello,S.R.
  TITLE     Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead
            box protein G1 (FoxG1) to promote neuronal survival
  JOURNAL   J Biol Chem 287 (18), 14749-14759 (2012)
   PUBMED   22354967
  REMARK    GeneRIF: TLE1 cooperates with FoxG1 to promote neuronal survival in
            a CK2- and PI3K-Akt-dependent manner.
REFERENCE   5  (bases 1 to 2815)
  AUTHORS   Yip,D.J., Corcoran,C.P., Alvarez-Saavedra,M., DeMaria,A.,
            Rennick,S., Mears,A.J., Rudnicki,M.A., Messier,C. and Picketts,D.J.
  TITLE     Snf2l regulates Foxg1-dependent progenitor cell expansion in the
            developing brain
  JOURNAL   Dev Cell 22 (4), 871-878 (2012)
   PUBMED   22516202
REFERENCE   6  (bases 1 to 2815)
  AUTHORS   Vyas,A., Saha,B., Lai,E. and Tole,S.
  TITLE     Paleocortex is specified in mice in which dorsal telencephalic
            patterning is severely disrupted
  JOURNAL   J Comp Neurol 466 (4), 545-553 (2003)
   PUBMED   14566948
REFERENCE   7  (bases 1 to 2815)
  AUTHORS   Tan,K., Shaw,A.L., Madsen,B., Jensen,K., Taylor-Papadimitriou,J.
            and Freemont,P.S.
  TITLE     Human PLU-1 Has transcriptional repression properties and interacts
            with the developmental transcription factors BF-1 and PAX9
  JOURNAL   J Biol Chem 278 (23), 20507-20513 (2003)
   PUBMED   12657635
REFERENCE   8  (bases 1 to 2815)
  AUTHORS   Hanashima,C., Shen,L., Li,S.C. and Lai,E.
  TITLE     Brain factor-1 controls the proliferation and differentiation of
            neocortical progenitor cells through independent mechanisms
  JOURNAL   J Neurosci 22 (15), 6526-6536 (2002)
   PUBMED   12151532
REFERENCE   9  (bases 1 to 2815)
  AUTHORS   Xuan,S., Baptista,C.A., Balas,G., Tao,W., Soares,V.C. and Lai,E.
  TITLE     Winged helix transcription factor BF-1 is essential for the
            development of the cerebral hemispheres
  JOURNAL   Neuron 14 (6), 1141-1152 (1995)
   PUBMED   7605629
REFERENCE   10 (bases 1 to 2815)
  AUTHORS   Tao,W. and Lai,E.
  TITLE     Telencephalon-restricted expression of BF-1, a new member of the
            HNF-3/fork head gene family, in the developing rat brain
  JOURNAL   Neuron 8 (5), 957-966 (1992)
   PUBMED   1350202
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000164.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by NM_012560.4.
            
            On Feb 10, 2021 this sequence version replaced NM_012560.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: M87634.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2815              JACYVU010000164.1  42962960-42965774
FEATURES             Location/Qualifiers
     source          1..2815
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q22"
     gene            1..2815
                     /gene="Foxg1"
                     /gene_synonym="BF1A; Fkhl1; RATBF1A"
                     /note="forkhead box G1"
                     /db_xref="GeneID:24370"
                     /db_xref="RGD:2619"
     exon            1..2815
                     /gene="Foxg1"
                     /gene_synonym="BF1A; Fkhl1; RATBF1A"
                     /inference="alignment:Splign:2.1.0"
     CDS             446..1888
                     /gene="Foxg1"
                     /gene_synonym="BF1A; Fkhl1; RATBF1A"
                     /note="forkhead-like transcription factor BF-1; BF1; brain
                     factor 1; forkhead-related protein FKHL1"
                     /codon_start=1
                     /product="forkhead box protein G1"
                     /protein_id="NP_036692.1"
                     /db_xref="GeneID:24370"
                     /db_xref="RGD:2619"
                     /translation="MLDMGDRKEVKMIPKSSFSINSLVPEAVQNDNHHASHGHHNSHH
                     PQHHHHHHHHHHPPPPAPQPPPPPPQQQQQPPPAPQPPQARGAPAADDDKGPQPLLLP
                     PSAALDGAKADALGAKGEPGGGPAELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGG
                     KEGDKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQN
                     SIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLA
                     FKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSS
                     VLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYS
                     LNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARAASSSTSPQAPSTLPCESLRPS
                     LPSFTTGLSGGLSDYFTHQNQGSSSNPLIH"
ORIGIN      
        1 gcggccgctc cgggacgcgc ccgcccgctg cccggctctc ccccccttcg ggctgccgct
       61 gctgctgctg tgactgctgc ggcgcgagga ggaggaggca gcgggggagg gggaggccgg
      121 gcgcggaacg gagcggggcg ctgcaccccg ggcgacgggt tgcttctgcc tctagcttct
      181 ctctctctct ctctctctct ctctctctct ctctctctct ctctctctct ctctctctct
      241 ctctaattct tgaggggtgg ttgcagcttt tgctacatgc cttgccagcg ccggagcctg
      301 cggtccaact gcgctgctgc cggagcgctc agtgccgccg ccgctgcccg ctccccccgc
      361 tccccactcc gaacccgccg gtcgctcgcc gcgctgctgc tcggctcctg cgccgccgcc
      421 gtcgccgccc cccgacgcct gggtgatgct ggacatggga gataggaaag aggtgaaaat
      481 gattcccaag tcctcgttca gcatcaacag cctggtccct gaggccgtcc agaacgacaa
      541 ccaccacgcg agccacggtc accacaacag ccaccacccc cagcatcacc atcatcatca
      601 ccaccaccac cacccgccgc cgcccgcgcc tcagccgccg ccaccgccgc cccagcagca
      661 gcagcagccg cccccggccc cgcagccccc gcaggcgcgc ggcgccccag cagcggacga
      721 cgacaagggc ccccagccgc ttctgctccc gccgtccgcc gccctggacg gggccaaggc
      781 tgacgcactt ggagccaaag gcgagccagg cggcgggcct gcggagctgg cgcccgtcgg
      841 gccggacgag aaggagaagg gcgcgggcgc tgggggggag gagaagaagg gggcgggcga
      901 gggcggcaag gacggggagg ggggcaagga gggcgacaag aagaacggca agtacgagaa
      961 gccgccgttc agctacaacg cgctcatcat gatggccatc aggcagagtc ccgagaagcg
     1021 cctgacgctc aacggcatct acgagttcat catgaagaac ttcccttact accgcgagaa
     1081 caagcagggc tggcagaact ccatccgcca caacctgtcc ctcaacaagt gcttcgtgaa
     1141 ggtaccgcgc cactacgacg acccgggcaa gggcaactac tggatgctgg acccgtcgag
     1201 cgacgacgtg ttcatcggcg gcacgaccgg caagctgcgg cgccgctcca ccacgtctcg
     1261 ggccaagcta gcctttaagc gcggggcacg gctcacctcc accggcctca ccttcatgga
     1321 ccgcgccggc tccctctact ggcccatgtc gcccttcctg tccctgcacc accctcgcgc
     1381 cagcagcact ttgagttaca acgggaccac gtcggcctac cccagccacc ccatgcccta
     1441 cagctccgtg ttgactcaaa actcgctggg caacaaccac tccttctcca ccgccaacgg
     1501 gctgagcgtg gaccggctgg tcaacgggga gatcccgtac gccacgcacc acctcacggc
     1561 cgctgcgctc gccgcctccg tgccctgcgg cctgtcggtg ccctgctccg ggacctactc
     1621 cctcaacccc tgctccgtca acctgctcgc gggccagacc agttactttt tcccccacgt
     1681 cccgcacccg tcaatgactt cgcagaccag cacgtccatg agcgcccggg ccgcgtcctc
     1741 ctctacgtcg ccgcaggccc cctcgaccct gccctgtgag tctttaagac cctctttgcc
     1801 aagttttacg acaggactgt ccgggggact gtctgattat ttcacacatc aaaatcaggg
     1861 gtcttcttcc aaccctttaa tacattaaca tcccggggac cagactgtaa gtgaacgttt
     1921 tacacacatt tgcattgtaa atgataatta aaaaataagt ccaggtattt tttattaagc
     1981 ccttcccccc atttctgtac gtttgttcag tctttagggt tgtttactat tctaacacgg
     2041 tgtggagtgt cagcgaggtg caatgtggga gaatacattg tagaatataa ggtttggacg
     2101 tcaaattata gtagaatgtg tatctaaata gtgactgctt tgccatttca ttcaaacctg
     2161 acaagtctat ctctaaaggc tgccagattt ccatgtgtgc agtattataa gttatcatgg
     2221 atctatctgg tggacgcagg ccttgaagaa caacctaaat tatgaagaga gttttaaaat
     2281 gttaaactgt aatttgtatt taagaatttg tagtaaaggt gcccaagaaa ttatattggc
     2341 catttattgt tttgtccttt tctttaaaga actgtttttt tcttttgttt acttttagac
     2401 caaagattgg attctagcaa atgcacttgg tatactaagt attaaaacaa gcaaacaaac
     2461 aaacaaaaaa ggaaggttgt ttagtttggc aacactgccc attcaattga atccgaagga
     2521 gacaaaatta aggattgcct tcagtttgtg ttgtgtatat ttcgatgtat gtggtcacta
     2581 acaggtcact tttatttttt ctaaatgtag tgaaatgtta atacctattg tacttatagg
     2641 taaaccttgc aaatatgtaa cctgtgttgc gcaaatgccg catcaatttg agtgattgtt
     2701 aatgttgtct taaaatttct tgattgtgat actgtggtca tatgcccgtg tttgtcactt
     2761 acaaaaatgt ttactatgaa cacacagaaa taaaaaatag gctaaattca tatat
//
