LOCUS       NM_001013248            2377 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus forkhead box B1 (Foxb1), mRNA.
ACCESSION   NM_001013248 XM_345949
VERSION     NM_001013248.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2377)
  AUTHORS   Zhao,T., Szabo,N., Ma,J., Luo,L., Zhou,X. and Alvarez-Bolado,G.
  TITLE     Genetic mapping of Foxb1-cell lineage shows migration from caudal
            diencephalon to telencephalon and lateral hypothalamus
  JOURNAL   Eur J Neurosci 28 (10), 1941-1955 (2008)
   PUBMED   19046377
REFERENCE   2  (bases 1 to 2377)
  AUTHORS   Zhao,T., Zhou,X., Szabo,N., Leitges,M. and Alvarez-Bolado,G.
  TITLE     Foxb1-driven Cre expression in somites and the neuroepithelium of
            diencephalon, brainstem, and spinal cord
  JOURNAL   Genesis 45 (12), 781-787 (2007)
   PUBMED   18064677
REFERENCE   3  (bases 1 to 2377)
  AUTHORS   Radyushkin,K., Anokhin,K., Meyer,B.I., Jiang,Q., Alvarez-Bolado,G.
            and Gruss,P.
  TITLE     Genetic ablation of the mammillary bodies in the Foxb1 mutant mouse
            leads to selective deficit of spatial working memory
  JOURNAL   Eur J Neurosci 21 (1), 219-229 (2005)
   PUBMED   15654859
REFERENCE   4  (bases 1 to 2377)
  AUTHORS   Kloetzli,J.M., Fontaine-Glover,I.A., Brown,E.R., Kuo,M. and
            Labosky,P.A.
  TITLE     The winged helix gene, Foxb1, controls development of mammary
            glands and regions of the CNS that regulate the milk-ejection
            reflex
  JOURNAL   Genesis 29 (2), 60-71 (2001)
   PUBMED   11170346
REFERENCE   5  (bases 1 to 2377)
  AUTHORS   Alvarez-Bolado,G., Zhou,X., Voss,A.K., Thomas,T. and Gruss,P.
  TITLE     Winged helix transcription factor Foxb1 is essential for access of
            mammillothalamic axons to the thalamus
  JOURNAL   Development 127 (5), 1029-1038 (2000)
   PUBMED   10662642
REFERENCE   6  (bases 1 to 2377)
  AUTHORS   Ang,S.L., Wierda,A., Wong,D., Stevens,K.A., Cascio,S., Rossant,J.
            and Zaret,K.S.
  TITLE     The formation and maintenance of the definitive endoderm lineage in
            the mouse: involvement of HNF3/forkhead proteins
  JOURNAL   Development 119 (4), 1301-1315 (1993)
   PUBMED   8306889
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jun 3, 2021 this sequence version replaced NM_001013248.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1522754.1,
                                           SRR26360194.1304655.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840117, SAMN12840121
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-380               JAXUCZ010000008.1  79290402-79290781   c
            381-2377            JAXUCZ010000008.1  79288161-79290157   c
FEATURES             Location/Qualifiers
     source          1..2377
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2377
                     /gene="Foxb1"
                     /note="forkhead box B1"
                     /db_xref="GeneID:367106"
                     /db_xref="RGD:1305217"
     exon            1..380
                     /gene="Foxb1"
                     /inference="alignment:Splign:2.1.0"
     exon            381..2377
                     /gene="Foxb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             435..1412
                     /gene="Foxb1"
                     /codon_start=1
                     /product="forkhead box protein B1"
                     /protein_id="NP_001013266.2"
                     /db_xref="GeneID:367106"
                     /db_xref="RGD:1305217"
                     /translation="MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIM
                     DRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSF
                     LRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMPAAAYNLGGV
                     AQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHV
                     YGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPAL
                     PAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH"
ORIGIN      
        1 cattaatgaa gcgccgctac aggggtcttt tctgctcctg tcaccgctta aaactatcag
       61 atggttcgag ggtggacatg gaggcagcca cctagctcag cggaaccacg aacgccacag
      121 cagcgtcttc tggatccccg aggcggcgtc tgccactgtc cccacccgca ctccacagct
      181 gagttcggcc tcccagcagg acgcaggacc caggagcgcc gcggagcccg cggagaggag
      241 ctctaccggg ctgagtccaa gccgggctgg cagcgagtct cactggtccc cgactctgcg
      301 ctcctatcgc gcgcagggag ggactcggcc accagccacg ccatcccgga tgcggaccag
      361 taacttggaa caactttaag atccgaccag tcctccgggc cctgcggacc ctgagcaagt
      421 ggccaagcaa gaagatgcct cggccgggcc gcaacacgta cagcgaccag aagccgccct
      481 actcctacat ctcgctgacc gccatggcca tccagagctc tccggagaag atgctgccgc
      541 tcagcgaaat ctacaagttc atcatggacc gcttccccta ctaccgggag aacacgcagc
      601 gctggcagaa cagcctgcgc cacaatctct ccttcaacga ttgcttcatt aagatcccgc
      661 ggcggccaga ccagccgggc aagggcagct tctgggcgct gcatcccagc tgcggggaca
      721 tgttcgagaa cgggagcttc ctgcggcgcc gcaagcgctt caaggtgctc aagtcagacc
      781 acctggcgcc cagcaagccg gcggacgccg cgcagtacct ccagcagcag gctaagctgc
      841 ggctcagcgc gctggccgcc tcgggcacgc atctgccaca gatgccggcc gctgcgtaca
      901 acctgggcgg tgtggcgcag ccctccggct tcaagcatcc ctttgccatc gagaatatca
      961 tcgcgaggga gtacaagatg cctgggggac tggccttctc tgccatgcag ccggttccgg
     1021 ctgcctaccc gctccctaac cagttaacta ccatgggcag ctctctaggc accggctggc
     1081 cccacgtgta cggttccgca ggtatgatcg actcagccac cccaatctcc atggccagtg
     1141 gcgactacag cgcctatgga gtgccgctga agccgctatg ccacgccgca ggccagacgt
     1201 tgcccgccat cccagtgccc atcaagccca ctccggccgc agtgcccgcg ctgccagcgc
     1261 tgccggcacc cattcctacc ctgctctcga actcgccgcc ttctctcagc cccacctcct
     1321 cgcagacagc cactagccaa agcagccctg ccacccctag cgagacactc accagcccgg
     1381 cctccgcctt gcactcggtg gccgtgcact gacccacaga agctggggct ccgtcttagt
     1441 ctcatccaca ccatccctct caacacttcc ccggctccgg gtccagccct ctgcgacctg
     1501 aaaccgccac ccggacttgc ccattctacc ttcttcagtc ctcgctctta ggagaacttt
     1561 tgattttgga cccagaagac aaaccacaaa cttgccagaa ggcgtgtgaa agttgtctgc
     1621 gtccctctag ggcagcagag aaaacagggg ctaacccaag ccaagcggtc cctccagggt
     1681 ccctgaaatg cactctcatc caacaggcag aacaccctga ctccctcctg ctcggagaaa
     1741 acagaaacaa aacaaaacaa aatacgcatc ttctgagctt ggataggcag ggctctggac
     1801 tcagcacaat ttcaagacca gagacactgc ccgagagcag aagcctgccg aggctgcagc
     1861 cacaacgtga aggccggatc ttcttaggtc ctgaaaatct gtggccacag gacccactaa
     1921 tcatccacca gattcgcctc cgcccatcag gccgggatgg gcggaccgct gctttcctcg
     1981 gctgcagccc tgcctccccg gcttctaaag attttttttc cccttctgag ttttgtttcc
     2041 ggccagaggc tcccttagct gggagtgagg agagaggctg ctaaacttcg gaggatgctt
     2101 gtcctactca caagcaaaac acagctaaaa gtcaccgtta ttgtttacaa agcgcgcggt
     2161 ttaaaaaaaa tgtaaacagt gaacttgaga atctgcctgg ctaggggcga gggggtagag
     2221 tcctctttac aattacctgt tgtaatgtga atgtttactc ttctggccag ctttgggggt
     2281 gggaaggagg tagggggaat gggggaagtt aatcgggatg ttaactttct tactagttag
     2341 agaccttttt agctatttat tttgatgaaa gagaaaa
//
