LOCUS       NM_001271163            6454 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus folliculin interacting protein 1 (Fnip1), mRNA.
ACCESSION   NM_001271163 XM_002727710 XM_003752329 XM_003752330
VERSION     NM_001271163.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6454)
  AUTHORS   Sager,R.A., Woodford,M.R., Backe,S.J., Makedon,A.M.,
            Baker-Williams,A.J., DiGregorio,B.T., Loiselle,D.R., Haystead,T.A.,
            Zachara,N.E., Prodromou,C., Bourboulia,D., Schmidt,L.S.,
            Linehan,W.M., Bratslavsky,G. and Mollapour,M.
  TITLE     Post-translational Regulation of FNIP1 Creates a Rheostat for the
            Molecular Chaperone Hsp90
  JOURNAL   Cell Rep 26 (5), 1344-1356 (2019)
   PUBMED   30699359
REFERENCE   2  (bases 1 to 6454)
  AUTHORS   Meng,J. and Ferguson,S.M.
  TITLE     GATOR1-dependent recruitment of FLCN-FNIP to lysosomes coordinates
            Rag GTPase heterodimer nucleotide status in response to amino acids
  JOURNAL   J Cell Biol 217 (8), 2765-2776 (2018)
   PUBMED   29848618
REFERENCE   3  (bases 1 to 6454)
  AUTHORS   Woodford,M.R., Dunn,D.M., Blanden,A.R., Capriotti,D., Loiselle,D.,
            Prodromou,C., Panaretou,B., Hughes,P.F., Smith,A., Ackerman,W.,
            Haystead,T.A., Loh,S.N., Bourboulia,D., Schmidt,L.S., Marston
            Linehan,W., Bratslavsky,G. and Mollapour,M.
  TITLE     The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and
            enhance drug binding
  JOURNAL   Nat Commun 7, 12037 (2016)
   PUBMED   27353360
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6454)
  AUTHORS   Goberdhan,D.C., Wilson,C. and Harris,A.L.
  TITLE     Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the
            Spot
  JOURNAL   Cell Metab 23 (4), 580-589 (2016)
   PUBMED   27076075
  REMARK    Review article
REFERENCE   5  (bases 1 to 6454)
  AUTHORS   Hasumi,H., Baba,M., Hasumi,Y., Lang,M., Huang,Y., Oh,H.F.,
            Matsuo,M., Merino,M.J., Yao,M., Ito,Y., Furuya,M., Iribe,Y.,
            Kodama,T., Southon,E., Tessarollo,L., Nagashima,K., Haines,D.C.,
            Linehan,W.M. and Schmidt,L.S.
  TITLE     Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles
            in kidney tumor suppression in cooperation with Flcn
  JOURNAL   Proc Natl Acad Sci U S A 112 (13), E1624-E1631 (2015)
   PUBMED   25775561
REFERENCE   6  (bases 1 to 6454)
  AUTHORS   Park,H., Staehling,K., Tsang,M., Appleby,M.W., Brunkow,M.E.,
            Margineantu,D., Hockenbery,D.M., Habib,T., Liggitt,H.D., Carlson,G.
            and Iritani,B.M.
  TITLE     Disruption of Fnip1 reveals a metabolic checkpoint controlling B
            lymphocyte development
  JOURNAL   Immunity 36 (5), 769-781 (2012)
   PUBMED   22608497
REFERENCE   7  (bases 1 to 6454)
  AUTHORS   Hong,S.B., Oh,H., Valera,V.A., Baba,M., Schmidt,L.S. and
            Linehan,W.M.
  TITLE     Inactivation of the FLCN tumor suppressor gene induces TFE3
            transcriptional activity by increasing its nuclear localization
  JOURNAL   PLoS One 5 (12), e15793 (2010)
   PUBMED   21209915
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6454)
  AUTHORS   Wang,L., Kobayashi,T., Piao,X., Shiono,M., Takagi,Y., Mineki,R.,
            Taka,H., Zhang,D., Abe,M., Sun,G., Hagiwara,Y., Okimoto,K.,
            Matsumoto,I., Kouchi,M. and Hino,O.
  TITLE     Serine 62 is a phosphorylation site in folliculin, the
            Birt-Hogg-Dube gene product
  JOURNAL   FEBS Lett 584 (1), 39-43 (2010)
   PUBMED   19914239
REFERENCE   9  (bases 1 to 6454)
  AUTHORS   Takagi,Y., Kobayashi,T., Shiono,M., Wang,L., Piao,X., Sun,G.,
            Zhang,D., Abe,M., Hagiwara,Y., Takahashi,K. and Hino,O.
  TITLE     Interaction of folliculin (Birt-Hogg-Dube gene product) with a
            novel Fnip1-like (FnipL/Fnip2) protein
  JOURNAL   Oncogene 27 (40), 5339-5347 (2008)
   PUBMED   18663353
REFERENCE   10 (bases 1 to 6454)
  AUTHORS   Baba,M., Hong,S.B., Sharma,N., Warren,M.B., Nickerson,M.L.,
            Iwamatsu,A., Esposito,D., Gillette,W.K., Hopkins,R.F. 3rd,
            Hartley,J.L., Furihata,M., Oishi,S., Zhen,W., Burke,T.R. Jr.,
            Linehan,W.M., Schmidt,L.S. and Zbar,B.
  TITLE     Folliculin encoded by the BHD gene interacts with a binding
            protein, FNIP1, and AMPK, and is involved in AMPK and mTOR
            signaling
  JOURNAL   Proc Natl Acad Sci U S A 103 (42), 15552-15557 (2006)
   PUBMED   17028174
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Feb 11, 2021 this sequence version replaced NM_001271163.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.25913.1,
                                           SRR26643297.34044.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               JAXUCZ010000010.1  39068464-39068664
            202-328             JAXUCZ010000010.1  39095117-39095243
            329-463             JAXUCZ010000010.1  39104394-39104528
            464-564             JAXUCZ010000010.1  39113455-39113555
            565-639             JAXUCZ010000010.1  39113815-39113889
            640-731             JAXUCZ010000010.1  39115488-39115579
            732-815             JAXUCZ010000010.1  39120358-39120441
            816-887             JAXUCZ010000010.1  39121913-39121984
            888-1023            JAXUCZ010000010.1  39124017-39124152
            1024-1225           JAXUCZ010000010.1  39126423-39126624
            1226-1311           JAXUCZ010000010.1  39128840-39128925
            1312-1458           JAXUCZ010000010.1  39132748-39132894
            1459-1628           JAXUCZ010000010.1  39133835-39134004
            1629-3045           JAXUCZ010000010.1  39135368-39136784
            3046-3214           JAXUCZ010000010.1  39137737-39137905
            3215-3412           JAXUCZ010000010.1  39143312-39143509
            3413-3528           JAXUCZ010000010.1  39146481-39146596
            3529-6454           JAXUCZ010000010.1  39148627-39151552
FEATURES             Location/Qualifiers
     source          1..6454
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..6454
                     /gene="Fnip1"
                     /note="folliculin interacting protein 1"
                     /db_xref="GeneID:100362347"
                     /db_xref="RGD:2318339"
     exon            1..201
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..3607
                     /gene="Fnip1"
                     /codon_start=1
                     /product="folliculin-interacting protein 1"
                     /protein_id="NP_001258092.2"
                     /db_xref="GeneID:100362347"
                     /db_xref="RGD:2318339"
                     /translation="MAPTLFQKLFSKRSGLGASGRDARDPDCAFSWPLPEFDPSQIRL
                     IVYQDCERRGRNVLFDSSVKRKNEDTSVSKLCNDAQVKVFGKCCQLKPGGDSSSSLDS
                     SITLSSDGKDQCPKYQGSRCSSDANMLGEMMFGSVAMSYKGSTLKIHQIRSPPQLMLS
                     KVFTARTGSSICGSLNTLQDSLEFINQDSNTLKADSSTVINGLLGNIGLSQFCSPRRA
                     FSEQGPLRLIRSASFFAVHSNPMDMPGRELSEDRDSGIARSASLSSLLITPFPSPNSS
                     LTRSCASSYQRRWRRSQTTSLENGVFPRWSIEESFNLSDESCGPNPGIVRKKKIAIGV
                     IFSLSKDEDENNKFNEFFFSHFPLFESHMNKLKSAIEQAMKMSRRSADAGQRSLAYNR
                     IVDALTEFRTTICNLYTMPRIGEPVWLTMMSGTPEKNQLCHRFMKEFTFLMENASKNQ
                     FLPALITAVLTNHLAWVPTVMPNGQPPIKIFLEKHSSQSVGMLAKTHPYNPLWAQLGD
                     LYGAIGSPVRLARTVVVGKRQDLVQRLLYFLTYFIRCSELQETHLLENGEDEAIVMPG
                     TVITTTLEKGEVEESEYVLITVHRNKSSLLFKESEETGTSNCNCKYCSHPLLGQNTEN
                     VSQLEREDIQDNSKELLGISDECQKIPPPDCQEENATDVQRYRDKLRARLDTKLETIV
                     CTGSAPADKCVLSETGLEPTEESWQSKELLDSDNQTGTAMRPTGIVVEKKPPDKTVPS
                     AFSCELTQTKVTFLIGDSMSPDSDTELRSQAVVDQINRHHSKPLKEDRGVTEKHQENK
                     ITKDQSGGSGTHNMVSGESCELPCWSHSDPESMSLFDEYFNDDSIETRTIDDVPVKTS
                     TDSKEYCCMLEYPKRLYTKDNKQQNELCKCIETVHQDSCNACFPQQDQRDALSILVPH
                     GDKESSDKKIAVGTEWDIPRNESSDSALGDSESEDTGPDIRRQVGSYCGGDQEDWAEE
                     DEIPFPGSKLIEVSAVQPNIANFGRSLLGGYCSSYVPDFVLQGIGSDERLRQCLASDL
                     SHAVQHPVLDEPIAEAVCIIADMDKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHS
                     TLQLYKHNLSPNFCVMHLEDRLQELYFKSKMLAEYLRGQMRVHVKELGVVLGIESSDL
                     PLLAAVASTHSPYVAQILL"
     exon            202..328
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            329..463
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            464..564
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            565..639
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            640..731
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            732..815
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            816..887
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1023
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1024..1225
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1311
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1458
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1459..1628
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..3045
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            3046..3214
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            3215..3412
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            3413..3528
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
     exon            3529..6454
                     /gene="Fnip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttctgtca tatgactgag gcgcccatgg gggtggcggg gcggcggtag gagcgggggg
       61 cctccggcga gctcccagcc gagcgacccc cggtctggag gcggccagca tggcccccac
      121 cttgttccag aagcttttca gcaagcggag cgggttaggc gcgtcgggac gagacgcccg
      181 cgacccggac tgcgcgttca gttggccctt gccagaattt gacccaagcc agattcgact
      241 gattgtatat caagactgtg aaagacgagg gagaaatgta ttgtttgact ccagtgttaa
      301 gagaaaaaat gaggacacat cagtatcgaa gctgtgtaat gatgctcaag tcaaggtctt
      361 tgggaagtgc tgccagctga agccaggggg agacagttct tcctctttgg atagctctat
      421 cactttatct tctgatggaa aagaccagtg tcccaaatac cagggttctc ggtgttcttc
      481 tgatgccaat atgcttggag agatgatgtt tggctcagta gcaatgagct acaaaggatc
      541 caccttaaaa attcatcaga tccgctctcc tccccagctc atgcttagca aagttttcac
      601 tgcacggact ggcagcagta tctgtggaag tctcaataca ctgcaagaca gtcttgaatt
      661 catcaatcag gacagtaata cattaaaggc tgatagcagc acagttatta atgggctgct
      721 tggaaatata ggtctttcac agttctgcag ccccaggcgg gcattctctg agcagggtcc
      781 gctccgcctg atcaggagcg cctctttctt tgcagttcac agcaacccaa tggacatgcc
      841 aggaagagaa ctgagtgagg acagagacag cggcatagca cgctctgcat ctctgagcag
      901 cctgctcatc accccatttc cctccccaaa ctcctcactc acccgaagct gtgccagcag
      961 ctaccagcga cgttggcgac gtagccaaac aacaagtttg gaaaatgggg tatttcctag
     1021 atggtctata gaagaaagct ttaatctgtc agatgaaagt tgtggcccta acccaggaat
     1081 tgtgaggaaa aagaagattg caattggggt aatcttttca ttatccaaag atgaagatga
     1141 aaataacaaa ttcaatgaat tctttttttc acattttcct ctctttgaaa gccacatgaa
     1201 caaattaaag agtgcaatag aacaggctat gaaaatgagc cggagatcag ctgatgctgg
     1261 ccagagaagt ttagcataca atcgaatagt tgatgccttg actgaattca gaacaacaat
     1321 ttgtaatctt tacacaatgc caagaattgg ggaacctgtg tggcttacaa tgatgtcagg
     1381 gactccagaa aagaaccagc tttgccatcg tttcatgaag gaattcactt ttctaatgga
     1441 aaatgcttcc aaaaatcaat tcttgccagc tctcattact gcagttttga ccaatcatct
     1501 tgcctgggtt ccaacagtca tgccaaatgg acagccacct ataaaaatat ttttagaaaa
     1561 acattcctct cagagtgtgg gcatgttggc aaagactcat ccatataacc ctctttgggc
     1621 acaacttgga gatttgtatg gcgctattgg gtctccagta cggttagcaa gaactgtagt
     1681 agttggcaaa cgacaagacc tggtccagag actgctttat tttcttactt actttatcag
     1741 atgctctgaa cttcaagaaa cccatctttt agaaaatgga gaagacgaag ccattgttat
     1801 gccaggcaca gtgattacta ccactttaga aaagggggaa gtagaggaat ctgagtatgt
     1861 gctgatcaca gtgcatagga acaaaagcag cttgctcttt aaagagtcag aagagacagg
     1921 aacttccaac tgtaactgta aatattgcag ccatccactc cttgggcaaa atacagagaa
     1981 tgtgtctcaa ctagagagag aagatattca agacaactct aaggaattgc tgggaatttc
     2041 agatgaatgc caaaagattc ctcctcctga ctgccaagaa gaaaatgcta ctgatgttca
     2101 gcggtacaga gataaattaa gagctcgtct tgacaccaag ttagagacaa ttgtttgtac
     2161 agggtctgct ccagcagaca aatgtgtgtt gtcagagaca ggcttggagc caacagaaga
     2221 atcctggcag agtaaggaat tgctggattc agataatcaa acaggcacag cgatgagacc
     2281 tacagggata gttgtagaaa agaaacctcc agataagact gtgcccagtg cattttcctg
     2341 tgagttaact cagacaaagg ttactttctt gattggagat tctatgtcac ctgattcaga
     2401 tactgaactt cggagtcagg ctgtggtgga tcagattaac agacatcata gcaaaccact
     2461 gaaggaagac agaggagtga ctgagaagca tcaagaaaat aaaatcacta aggaccaatc
     2521 tggaggctct ggcacacata acatggtttc tggagagtcc tgtgagcttc cttgttggag
     2581 tcattcagat ccagaaagca tgagcctctt tgatgaatat tttaatgatg attcgattga
     2641 aaccaggact attgatgatg ttccagttaa aacaagtaca gatagtaaag agtattgctg
     2701 tatgttggag tatccaaaaa gattgtatac aaaagataac aaacagcaaa atgaactttg
     2761 taaatgtata gaaacagttc atcaagattc gtgtaatgcc tgctttcctc agcaggacca
     2821 gagagatgcc ctctctattc ttgtccccca tggggataaa gagagttcag acaaaaaaat
     2881 tgctgtagga actgaatggg acattccaag aaatgaaagt tcagatagtg cccttggaga
     2941 tagtgagagt gaagacacag gtcctgacat aagaagacaa gttggcagtt actgtggagg
     3001 ggatcaggaa gattgggcag aagaggatga gatacctttc cctgggtcaa agttgattga
     3061 agtgagtgct gttcagccca acattgccaa ctttggaaga tccttgctgg gtggctactg
     3121 ctcatcttat gttcctgact ttgttcttca aggaattggg agtgatgaga ggctccgtca
     3181 gtgcctggca tcagatttgt cccatgctgt gcagcatcca gtgttagatg agccaatagc
     3241 agaagctgtc tgtattatag ctgatatgga taaatggact gttcaagtgg ccagcagtca
     3301 gagacgggtg acagataata aattgggaaa ggaggtgttg gtttccagtc ttgtttccaa
     3361 cctgcttcat tctactcttc agctttataa acataacttg tctccaaact tttgtgtaat
     3421 gcaccttgaa gaccggctac aggagttata cttcaagagc aaaatgctgg ctgagtacct
     3481 gaggggacag atgcgtgttc atgtcaagga gctaggagta gttcttggga tcgaatccag
     3541 tgaccttccc cttctggctg ctgtagcaag cacccactct ccatatgtcg ctcagatact
     3601 cctttaacat gtccagagga gaacatggtt caaagttgaa tagaaaccaa ggagataggc
     3661 acagtgtgta tctgtggagt tgttgctgtt ctgttttgta tttgtccatt ctgcttctgg
     3721 gtgaatgtgt caccccatgc ttgttgcatt gcagtgtgta tagaccagat gactttttat
     3781 ttctaactgc acatctgggt agtggtagat tttcaaccaa gtaaaactaa atcaaaataa
     3841 ttggggagat gtggaggggt ggaatttgca aaagccaaag tgtaacttag aatttctgtg
     3901 aatatccaga aatttcatgc aaactctaaa atgttgtcac aactcatgaa tagcaatagt
     3961 tgtctcatga tcaaatgtca gaaatcttca ttcactgatt tttaattttt atttctatgg
     4021 tacagaaatc tataagacct tgatttgttt gttgttttgc aattcagatc aactaatttc
     4081 tagttattta agtatttttt ttaaaaaaac ctgttaatta tgagaaactc agaatgagtg
     4141 acgatgtcat gtgctcatct gaagtgtaca tatgtatcta ttttttttaa aaaagcaggg
     4201 gtggaaatac aatattgata aacatgcctt tttaaaaaat attttttcat ctagtattgt
     4261 atataatgtt gaaatactac cttctgatga tttttttctg tttcacacat tctaaaatat
     4321 atttaaagcc aatctttcag aggctaaaag ttgtagattc cctaagaata ctacttttta
     4381 ccatttgttt tctaagaata agctaattct taatgatatt tgcatattaa tttaataaat
     4441 aaaaattaag attaaaaagt gcaccaaagc aatggcaaaa atactgtatt ttttaaatat
     4501 gctcaggtgg ccacaaacca gtatcaacca ttataaaccc atgtgagcag aatatttcct
     4561 aacaattttc aatttacact agtagaagta ataactttaa aattattctt tctttaagtg
     4621 ttcctttaaa atattgattg cttttcaaag ctttccattt atcctttgtc atcctctttg
     4681 tatataatgt agattgttgc tgtaagaaag gctaataagg aaccaaactc ttgtaagtaa
     4741 tgtaaatagg aaggtgggta gatcatgttt tcagtatact ctactacctc agtttacttg
     4801 aatactgaat tatagcttac tctctgcttg tgtgggctag aattaaagtt ggtttctgtt
     4861 ttcatttact aattctaaat tgtttagctc aaaaaaaaaa agatagaaaa caacataaaa
     4921 ctcccaaaac aaccctaccc acgtgtttgg ttactgaata cttttattat aacacatcca
     4981 ttcttgctat ttaaaatttt cagtaattaa taaaaatttc tgtggtttat agtctttaga
     5041 atcttgaatt tatgtgtctg gttacattta tcttgctctt tatgtgagtt caagagaatt
     5101 ccaactagaa aagaataaat aggacgtttt aatggaacat aaacccaaaa ttagggtatc
     5161 tgcagttggc ccttgttctg ttggttggtt ccagttagta cctgggtctc ccatggatga
     5221 cttggtgcca aagagttttt tatagatgtg gggttttggt cttttgttgt tttttttttt
     5281 ttttttttga tgtccttgta acccatttgt tagtggaatt gctctgttgt attctgttga
     5341 aattcagtga gtagatttgt gttagaattt agaatctcag aaagtttcct atgggccatt
     5401 gtacattatt tttgattgtg gctcagaata tatgtagcag gtagaaatgt ctgggatgtt
     5461 ttcttaaact tggagctttt catagttcta tctgaaatct ctcattacta cttagtaatt
     5521 ctagtcttta ataagtgaat ggcttgtgca cctaatattc tcaaacctca gctttgctgg
     5581 aaaggcctgt agtttcttaa aaactctcta gtccttgtaa gattccctga ttttataatg
     5641 ctttgatcat catattcttt acttactcag agcccaagga atgagctgct acttctttac
     5701 agtgtggctg tgataaatgt gaagagagtt ttggcctgtt taataatttt tcaactactt
     5761 aatggtacag ataaatatgt gctacatgtt aaaaatacct gttcattgtt acaggaaatt
     5821 aaaaagggat cttttatatt ataggattaa aactaatttt ctgtatatgt taactaattg
     5881 atttgatttt aaatatcttg catttattaa tatgtcttaa tattgaattt gaaactatta
     5941 agtgcaataa acattactac agatttcatt ttgttgcagt tggcacacag tgcagatgat
     6001 cactaaaaat aatttgcata atgcctacat ccagtagctg tcttatgaga atgttctgct
     6061 ttctcttaag ttatttagat gatgactata taaaatgtac atacttgttt gttgttctga
     6121 atacatttct caaatgtaca cctgtattat aataacctcc cagttctagg ggaaatttgt
     6181 gcaataaaca ctcatgtcaa tttgatgggt aatgtttgtg tttctttcat atgttaatga
     6241 ggcatatatt actattttgg actctgaata tcagacaacc taggttgatg aacatgtgac
     6301 ctttctatat tgataaaatc tgttaatact tcattagatt gtgagagttg agtaaaataa
     6361 tgattgttaa gaatgtaact aaatgccaag actttttgcc aggtaaccgg aatagttgcc
     6421 atataatgtt catagaattt ttaatatatg cttt
//
