LOCUS       NM_001105846            3659 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus formin-like 1 (Fmnl1), mRNA.
ACCESSION   NM_001105846 XM_001081542 XM_213487
VERSION     NM_001105846.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3659)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3659)
  AUTHORS   Mason,F.M., Heimsath,E.G., Higgs,H.N. and Soderling,S.H.
  TITLE     Bi-modal regulation of a formin by srGAP2
  JOURNAL   J Biol Chem 286 (8), 6577-6586 (2011)
   PUBMED   21148482
REFERENCE   3  (bases 1 to 3659)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 3659)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 3659)
  AUTHORS   Yayoshi-Yamamoto,S., Taniuchi,I. and Watanabe,T.
  TITLE     FRL, a novel formin-related protein, binds to Rac and regulates
            cell motility and survival of macrophages
  JOURNAL   Mol Cell Biol 20 (18), 6872-6881 (2000)
   PUBMED   10958683
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001081542.1, XM_213487.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680431,
                              SAMN06680451 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3659
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..3659
                     /gene="Fmnl1"
                     /note="formin-like 1"
                     /db_xref="GeneID:287746"
                     /db_xref="RGD:1311042"
     exon            1..281
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..3257
                     /gene="Fmnl1"
                     /codon_start=1
                     /product="formin-like protein 1"
                     /protein_id="NP_001099316.1"
                     /db_xref="GeneID:287746"
                     /db_xref="RGD:1311042"
                     /translation="MGNAAGSAEQPAGPTASPPKQPAVPKQPMPAAGELEERFTRVLN
                     CMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKSYLDTGGVSRKVAT
                     DWMSNLGFKRRVQESTQVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCS
                     VAYDMESTENVASGTEKNKPLEQSVEDLSKAPPSSVPKSRLTIKLTPAHSRKALRNSR
                     IVSQKDDVHVCIMCLRAIMNYQVCGEQHRFEKLMEYFRNEDSNIDFMVACMQFINIVV
                     HSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETE
                     TKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQLSQARKELETLRERFSES
                     TPMVTSRRIPEPEKVPAPTVVRPSALELKVEELEEKGLIRILRGPGDVVSIEILPGAA
                     ATPSGDDAPAPRVSTDSPSTAESVPEAASPTPPPPPPPPPPLPNLQSQQEALPSAPPL
                     APPLPGCAAPPPAPPLPGDLPPPPPPPPLGTDGPVPPPPPPPPGGPPDILGGQDPEIG
                     PGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEQFKTKS
                     QGPSLDISALKGKTAHKAPTKATLIEANRAKNLAITLRKGNLGADRICEAIETYDLQT
                     LSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTL
                     TFLGNFPDTAQLLMPQLNAIIAASISIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGF
                     RLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLG
                     DVRSLQRGLELTQREFVRQDDCLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFG
                     ENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAADTSGREEPPAPKSPPKARRQ
                     QMDLISELKRKQLKEPLIYESDRDGAIEDIITVLKTVPFTARTGKRTSRLLCEASLGE
                     EMTL"
     exon            282..365
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            366..479
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            480..553
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            554..637
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            638..763
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..872
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            873..947
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1058
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1208
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1310
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1563
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1854
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..1979
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..2182
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2417
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2418..2486
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2487..2567
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2568..2697
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2861
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..2963
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            2964..3044
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3165
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3166..3264
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
     exon            3265..3659
                     /gene="Fmnl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgcacgcc gctgagctga gagcagccta gcccagcccc gccatccagt gctgcccttc
       61 gcccccctgg ctcccgaagc ctagtccgcg acccccaggg aaaactggat ctccgaggct
      121 ggagacgctt ggccggctgg gtggggacca ccatgggcaa cgcggctggc agcgctgagc
      181 agcccgcggg ccccaccgca tcgcccccga agcagccagc cgtccccaag caaccgatgc
      241 cggcggccgg ggagctggag gagaggttca cgcgagtctt gaactgtatg aacttgcctc
      301 ccgacaaagt ccagctgctg agccagtatg acaatgagaa gaaatgggag ctcatctgtg
      361 accaggagcg gtttcaagtc aagaatcccc ctgcagccta cattcagaag ctgaagagct
      421 acttagatac cggtggggtc agccgaaagg tagcaactga ttggatgtcc aacctggggt
      481 ttaagaggcg agttcaggag tctactcagg tgctgcggga gctggagacc tccctgagga
      541 caaaccacat tgggtgggtg caggagttcc tcaatgaaga gaaccgaggt ctggatgtcc
      601 tgcttgagta cctggccttt gcccagtgct ctgttgcgta tgacatggaa agcacagaaa
      661 atgtggcctc aggcacagag aagaacaagc ccttggaaca gtccgtggaa gacctcagca
      721 aggcgccacc ctcatctgtg cccaaaagtc gcctgaccat caagctgacc cccgcccaca
      781 gcaggaaggc actgaggaat tcccggattg tcagccagaa ggacgacgtc cacgtgtgca
      841 tcatgtgtct gagagccatc atgaactacc aggtgtgcgg ggagcagcac agatttgaaa
      901 agctaatgga gtatttccgg aatgaagaca gcaacattga cttcatggtg gcttgcatgc
      961 agttcatcaa catcgtggta cactcggtgg agaacatgaa cttccgtgtc ttcttgcaat
     1021 atgagttcac tcacttgggt ctggacctgt acttggagag gctccggctc accgagagtg
     1081 acaagctgca ggtgcagatc caggcatacc tggataacgt ttttgacgtg ggaacactgt
     1141 tggaggagac cgagactaag aatgcagtgc tggagcacat ggaggagctg caggagcagg
     1201 tggcaacgct gacagagcgg cttcgggaca cagagaacga ctccatggcc aagatcgctg
     1261 aactggagaa gcagctaagc caggctcgca aggaattgga gaccctgagg gagcgcttca
     1321 gcgagtcgac ccccatggtc acttccagac gaatccctga acctgagaaa gtgcctgctc
     1381 ctaccgtggt gcgaccctca gctcttgagc tgaaggtgga agagcttgaa gaaaaggggt
     1441 taatccgtat cctgcgggga ccgggggatg tcgtctccat cgagatcctc cccggcgctg
     1501 cggcgacacc aagcggtgac gacgcaccag ctccgagggt gtccactgat tcccctagca
     1561 cagcagagtc agttcccgaa gcagcatcac caacgcctcc gccacctccg ccacctccac
     1621 ctccactacc taacctccag tcccagcagg aagcccttcc ctctgcaccc ccgctggccc
     1681 cgcccctccc aggctgcgca gcgccgccac ctgcaccacc gttgcctgga gacctgcctc
     1741 ccccacctcc accaccccca cttggaactg atggaccggt gccaccgcca ccgccaccac
     1801 ctccaggagg gccccctgat atccttggag gacaagaccc agagataggc ccaggggtga
     1861 aagccaagaa acccatccag accaagttcc ggatgccatt gcttaactgg gtggcgctga
     1921 aacccagcca gatcacaggc accgtcttta ctgagctcaa tgatgagaag gtgctgcagg
     1981 agttagacat gaatgacttt gaggagcagt ttaagaccaa atcccaaggc cccagcctgg
     2041 acatcagcgc tctgaagggg aagacagccc acaaagcccc aactaaggca accctcattg
     2101 aagccaacag ggccaagaat ttggccatca ccctgcgcaa gggcaaccta ggagctgaca
     2161 gaatctgcga ggccattgag acgtatgacc tccagactct cagcctggat ttcttggagc
     2221 tgttgacccg cttcctgccc acagactacg agcgtagcct catagcccga tttgagaagg
     2281 agcagcggcc aatggaagag ctgtcagagg aggaccgctt catgctgcgc ttcagtcgca
     2341 tccagaggct tccagagcga atgaatacac tcaccttcct gggcaacttt ccagacacgg
     2401 cccagctgct catgccgcaa ctgaacgcca tcattgcagc ctctatatcc atcaagtcct
     2461 ctgacaagct tcgccagatc ctagagatcg tcctggcttt tggcaactac atgaacagta
     2521 gtaagcgtgg ggcagcctat ggtttccgac ttcagagtct ggatgcgttg ttggagatga
     2581 agtcgactga ccggaaacag acgttgctgc attacttggt gaaggtcatt gctgagaagt
     2641 acccacagct cacgggcttt catagcgacc tgcacttctt ggataaagca ggctcagtgt
     2701 ccctggacag tgtgctggga gacgtgcgct ccttgcagcg aggtctggag ttgacacaaa
     2761 gagagtttgt gcggcaagat gactgcctgg tgctcaaaga attcctgagg gctaactctc
     2821 ccaccatgga caagctactg gcagacagca agacagccca ggaggcctac gagtccgtgg
     2881 tggagtactt tggagaaaat cccaagacca catccccctc catgtttttt tccctcttca
     2941 gtcgcttcac caaggcctac aagaaagcag agcaggaggt ggaacaatgg aagaaggaag
     3001 cagccgcgga cacctcaggc agggaagagc ctccagcacc caagtctcct cccaaggcca
     3061 ggcgacaaca gatggacctc atctctgagc taaaacggaa gcagctgaaa gaaccactca
     3121 tctatgagag tgaccgagat ggggccattg aagacatcat cacagtgctc aagacagtgc
     3181 ccttcactgc ccgtactggc aagcggacat cccggctcct ctgtgaggcc agcctgggag
     3241 aggagatgac cctctagctc ccagatcttc ggaaccagcc ctacatccgt gcagacacag
     3301 gacgccgaag tgctcgccgg cgcccccctg gacccccact gccggtcact gctgacctct
     3361 cgctgtagcc actgtttctg ctggtggatt ctatagggcc ataggcaggt tggagctcaa
     3421 aggtggtggt ccttagctcg gctggatcgg gcatctgctc cttctagact actagccttg
     3481 aagacccccc cccccccaaa aaaagctggt cccagcaccc tctccctcca atagccataa
     3541 ttagcctgag cgggatcctg gcctgtaact tataaagtgc acctcgccgc cgccctaact
     3601 cggaggactc tccttggacc ttatttttat acaagattaa taaagatgtt tgcaaaaga
//
