LOCUS       NM_199109               3401 bp    mRNA    linear   ROD 20-OCT-2024
DEFINITION  Rattus norvegicus FLVCR choline and putative heme transporter 2
            (Flvcr2), mRNA.
ACCESSION   NM_199109 XM_234424
VERSION     NM_199109.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3401)
  AUTHORS   Duffy,S.P., Shing,J., Saraon,P., Berger,L.C., Eiden,M.V., Wilde,A.
            and Tailor,C.S.
  TITLE     The Fowler syndrome-associated protein FLVCR2 is an importer of
            heme
  JOURNAL   Mol Cell Biol 30 (22), 5318-5324 (2010)
   PUBMED   20823265
REFERENCE   2  (bases 1 to 3401)
  AUTHORS   Brasier,G., Tikellis,C., Xuereb,L., Craigie,J., Casley,D.,
            Kovacs,C.S., Fudge,N.J., Kalnins,R., Cooper,M.E. and Wookey,P.J.
  TITLE     Novel hexad repeats conserved in a putative transporter with
            restricted expression in cell types associated with growth, calcium
            exchange and homeostasis
  JOURNAL   Exp Cell Res 293 (1), 31-42 (2004)
   PUBMED   14729055
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Nov 27, 2020 this sequence version replaced NM_199109.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101899.1, SRR26643429.24695.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1015              JAXUCZ010000006.1  111139352-111140366
            1016-1157           JAXUCZ010000006.1  111177076-111177217
            1158-1298           JAXUCZ010000006.1  111179930-111180070
            1299-1366           JAXUCZ010000006.1  111188689-111188756
            1367-1470           JAXUCZ010000006.1  111190736-111190839
            1471-1581           JAXUCZ010000006.1  111194611-111194721
            1582-1687           JAXUCZ010000006.1  111195821-111195926
            1688-1799           JAXUCZ010000006.1  111196049-111196160
            1800-1855           JAXUCZ010000006.1  111196765-111196820
            1856-3401           JAXUCZ010000006.1  111201800-111203345
FEATURES             Location/Qualifiers
     source          1..3401
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..3401
                     /gene="Flvcr2"
                     /note="FLVCR choline and putative heme transporter 2"
                     /db_xref="GeneID:314323"
                     /db_xref="RGD:735098"
     exon            1..1015
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..1936
                     /gene="Flvcr2"
                     /note="feline leukemia virus subgroup C receptor-related
                     protein 2; CCT; calcium-chelate transporter; feline
                     leukemia virus subgroup C cellular receptor family, member
                     2; heme transporter FLVCR2; FLVCR heme transporter 2"
                     /codon_start=1
                     /product="choline/ethanolamine transporter FLVCR2"
                     /protein_id="NP_954540.3"
                     /db_xref="GeneID:314323"
                     /db_xref="RGD:735098"
                     /translation="MVNESLNQEESNDRPVPESEFQADTSYSTQPSVSIHPSVSGHPS
                     VSIHPSVSGHPSVSIDPSVSVHPSSSAHPSTLAQPSGLTHPNELVKEDSVIKVSKRRW
                     AVVLVFSCYSLCNAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAW
                     MLEKFGLRTIAITGSALNCLGAWVKLGSLEPHLFPVTMVGQVICSVAQVFILGMPSRI
                     ASVWFGANEVSTACSMAVFGNQLGIAIGFLVPPVLVPNIKDQEKLAYHISIMFYIIGG
                     VATLLFILVIIVFKEKPKYPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITY
                     GLNAGAFYALSTLLNRMVIMHFPGQEVNAGRIGLTIVIAGMFGAMISGIWLDKSKTYK
                     ETTLVVYIMTLVGMVVYTFTLNLNHLWIVFITAGSLGFFMTGYLPLGFEFAVELTYPE
                     SEGVSSGLLNVSAQVFGIIFTISQGQIIDNYGSVPGNIFLCVFLALGSALTAFIKSDL
                     RRQRANKDAPETKVQEEEEEEEESNTSKVPTVLSEAHL"
     exon            1016..1157
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1298
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1366
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1470
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1581
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1687
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1688..1799
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1855
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..3401
                     /gene="Flvcr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actttttcca ggacagtcaa cgcttcatcg ggacagcctg gagcgcgtga caaggcgtct
       61 gtggccgact tgggggacaa cagtttgaga ggagggaaac aaaggatccc aaggaccagt
      121 gagatagttt gggaaagcga agtgtaggaa gctgagatct caatttctcc gccaacagag
      181 gtgcgctccg ggacaagtgt ttcctcagct ctagggggac aggctttaaa aggctgctga
      241 cccataagac tgtaggagtc agtacgtgcc tggggttcag gagctcgctg tggtcatggt
      301 gaatgaaagt ctcaaccagg aggagagcaa tgacagacct gtgccagagt ccgaattcca
      361 ggcggacacc agctactcca cccagcccag cgtctccatc caccccagcg tctcaggcca
      421 ccccagtgtc tccatccatc ctagtgtttc gggacacccc agcgtctcca tcgaccccag
      481 cgtctctgtc catcccagca gttcagcaca ccccagtacc ttggctcaac ccagtggttt
      541 gacccatcct aatgaattag ttaaagaaga cagcgtgatc aaggtgagca agcgtcgttg
      601 ggccgtggtc ctggtgttca gttgctactc cttgtgcaac gccttccagt ggatccagta
      661 tggctcgatc aataacatct tcatgaactt ctacggtgtc agcgcgtttg ccatcgactg
      721 gctgtccatg tgctacatgc tgacctacat ccctctgctc ctgccggtgg cctggatgct
      781 ggagaagttt ggtcttcgaa ccatcgctat caccggctcg gctctcaatt gcctgggagc
      841 ctgggtaaag ctaggcagcc tagagcctca cctcttcccg gtcacaatgg tgggtcaggt
      901 catctgctct gtggcacagg tcttcatcct gggcatgccc tcacgaattg cttccgtctg
      961 gttcggggct aatgaggtct caacagcctg ctccatggct gtgtttggca atcagcttgg
     1021 aattgcaatt gggtttttgg tccctcctgt tctggtaccc aacatcaaag accaggaaaa
     1081 gcttgcctac cacatcagca tcatgttcta cataatagga ggtgtggcca ctctcctctt
     1141 catccttgtc atcatcgtat tcaaggagaa gcccaagtac cctcccagca gggcccagtc
     1201 cttgagctac gccttggcga ccactgatgc ttcgtactta agttccattg tccggctctt
     1261 caaaaacctc aactttgtgc tgctggtcat cacctatggt ctgaatgctg gtgctttcta
     1321 tgccttatcc actctgctga atcgcatggt gatcatgcac tttccggggc aagaagtgaa
     1381 tgctggaaga attggtctga ccattgtcat cgcggggatg tttggagcta tgatctcggg
     1441 catctggctg gataaatcca aaacctacaa ggagacaacc ctggtagtgt atatcatgac
     1501 tctggtgggc atggtggtat atacattcac cttgaacctg aaccatttgt ggatagtatt
     1561 catcactgct ggctcactag gcttcttcat gactggctat ctgcccttgg gctttgagtt
     1621 tgctgtggag ctcacatacc ccgagtctga aggtgtgtcg tctggcctcc tcaacgtgtc
     1681 agcacaggta ttcgggatca tcttcaccat ctcccaaggc cagattattg acaactatgg
     1741 atccgtgcct gggaacatct tcctgtgtgt gttccttgcc ctcggatcag ctctaacagc
     1801 tttcattaag tcagatcttc ggaggcagag ggcgaacaag gatgctcctg agaccaaagt
     1861 ccaggaggag gaagaggagg aggaagagag caataccagc aaggtaccca ccgtcctgtc
     1921 ggaggctcat ctctgagaga gatagcagag actcaggaac acagacactc actcacctca
     1981 tggttccagt tagctgttac tgccagcact tagattttca cggagaaact tttggaagcc
     2041 actggaagat gtgtgcatgc cttgcatggc agtgcctaag cctactggac tctacctgag
     2101 aacctggatg gtttactcag ggaaaacctc acctctcttc agatgcagac tggattctgg
     2161 tccccagtcc ctgttaggtc ttgggctagt gttgggagag gctgtggagg gtgttggagt
     2221 ccatccttgc ttggtctctc accttctctc atccctttct tcactcatgg agaatgcttg
     2281 caaaattatc ctaagaaagc ttattcagga tattaacttt ttctaatgtc ttatggccac
     2341 ttcttatgag aatggggagc tgctctgcct gagggtcgtg agaggaagcg ccagagcagg
     2401 cccatcatcc caacccttgg ccttggccct tccccctagc tctgcagcat ttcttcagat
     2461 cctctttcct gagagtcaag gagactaaac accaataaac cagacacaac cttcgtggcc
     2521 ccaaaggaga aaccgattag agggttctct gcctagatgt gagagggcta ggggctactg
     2581 tgtgtgtgga gctctgcact gggatgaagg tgtttcctac aaaggtggtg ctcgctcagg
     2641 gccttctgtg tcccaggcca ctcagaatat ctttcttgga tattgcactg ggaaatgcag
     2701 ccatcagggg ctcatggctc taacctttat taaaagtttc tctcactcac tctactctga
     2761 cacataaggc tatctctgag gaaagaggta gaaggtggct cttaaaatag acatgtctgt
     2821 ttcagttaaa cacgatccta tgtatgctga ggactatatt cgaacccttt ccctgcccct
     2881 gctagcagga atctttgtca ggtgttttac gtttaaaagg attccattta aaccaattcc
     2941 agttgacctt tttccccacc actaacaggc tttcgtggtg tcttccccaa agagaaactg
     3001 gcagctaatt gctcctgtgc cttgagcagc tctggtcatg gatcttagtg tgtctggcct
     3061 tagcatacca gatcgcccag tttgcctgca gtactgggat actgggccag agggtatgtg
     3121 attgcgtgta cacacatgcg ttttgtgtgt gtgtgtgtgt atatgtgtgt gtacgtgtat
     3181 agacctgagc agtggatagg agggagggaa gcagccgtct ggtggaggga gtgttaggga
     3241 tggatcagag agaagcctta ctttctgtca agagaaaggt gtttttttct tcaactgttc
     3301 aaagtggaca tgtttactca atccatttat ttaaaaaaac ataatttgta tttcctgttt
     3361 gtaacagaag atattttaag gcaataaaga ttttcaaagt g
//
