LOCUS       NM_001109160            5461 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus fibronectin leucine rich transmembrane protein 1
            (Flrt1), mRNA.
ACCESSION   NM_001109160 XM_001076478 XM_574608
VERSION     NM_001109160.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5461)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
REFERENCE   2  (bases 1 to 5461)
  AUTHORS   Yamagishi,S., Hampel,F., Hata,K., Del Toro,D., Schwark,M.,
            Kvachnina,E., Bastmeyer,M., Yamashita,T., Tarabykin,V., Klein,R.
            and Egea,J.
  TITLE     FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive
            neurons
  JOURNAL   EMBO J 30 (14), 2920-2933 (2011)
   PUBMED   21673655
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5461)
  AUTHORS   Wheldon,L.M., Haines,B.P., Rajappa,R., Mason,I., Rigby,P.W. and
            Heath,J.K.
  TITLE     Critical role of FLRT1 phosphorylation in the interdependent
            regulation of FLRT1 function and FGF receptor signalling
  JOURNAL   PLoS One 5 (4), e10264 (2010)
   PUBMED   20421966
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5461)
  AUTHORS   Haines,B.P., Wheldon,L.M., Summerbell,D., Heath,J.K. and Rigby,P.W.
  TITLE     Regulated expression of FLRT genes implies a functional role in the
            regulation of FGF signalling during mouse development
  JOURNAL   Dev Biol 297 (1), 14-25 (2006)
   PUBMED   16872596
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_574608.2, XM_001076478.1.
FEATURES             Location/Qualifiers
     source          1..5461
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..5461
                     /gene="Flrt1"
                     /gene_synonym="RGD1565152"
                     /note="fibronectin leucine rich transmembrane protein 1"
                     /db_xref="GeneID:499308"
                     /db_xref="RGD:1565152"
     exon            1..5461
                     /gene="Flrt1"
                     /gene_synonym="RGD1565152"
                     /inference="alignment:Splign:2.1.0"
     CDS             1..2025
                     /gene="Flrt1"
                     /gene_synonym="RGD1565152"
                     /note="fibronectin leucine rich transmembrane protein 3"
                     /codon_start=1
                     /product="leucine-rich repeat transmembrane protein FLRT1"
                     /protein_id="NP_001102630.1"
                     /db_xref="GeneID:499308"
                     /db_xref="RGD:1565152"
                     /translation="MVVAHPAATATTTPAATVTATVVMTTATMDLRDWLFLCYGLIAF
                     LTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDL
                     KTKVKVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDD
                     NSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAF
                     KGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLY
                     LQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGC
                     NLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGSQGSAANAAA
                     KTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLVIQVKPLTADS
                     IRITWKAMLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMV
                     TMETGNTYVADETPVCAKAETADSYGPTTTLNQEQNAGPMAGLPLAGIIGGAVALVFL
                     FLVLGAICWYVHRAGELLTRERVYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPI
                     NPYRSKEEYVVHTIFPSNGSSLCKGAHTIGYGTTRGYREGGIPDVDYSYT"
ORIGIN      
        1 atggtggtgg cacaccctgc tgccaccgct accaccacac ctgctgccac tgtcacagcc
       61 actgtcgtga tgaccacagc caccatggac ctgcgggact ggctgtttct ctgctatggg
      121 cttattgcct tcctcacgga ggtcatcgac agcaccacct gcccatcagt gtgccgctgt
      181 gacaatggct tcatctactg caatgaccgg gggctcacat ccatcccctc agacatccct
      241 gatgacgcca ccaccctcta cttacagaac aaccagatca acaatgcagg catccctcag
      301 gacctcaaga ccaaggtcaa ggtgcaggtc atctacctat atgagaatga cctggatgag
      361 ttccctatca atctcccccg ctccctgcga gagctgcatc tgcaggacaa caatgtgcgc
      421 accattgcca gggactcctt ggctcgcatc ccgctgctgg agaagctgca cctggatgac
      481 aactccgtgt ccactgtgag catcgaggag gacgctttcg ctgacagcaa gcagctcaag
      541 ctgcttttcc tgagccgcaa ccacctgagc agcattccat cggggctgcc gcacaccctg
      601 gaggaactga ggctcgatga caaccgcatt tctaccatcc ccctgcacgc attcaagggg
      661 ctcaacagcc tgcgacgcct cgttctggat ggcaacttgc tggccaacca gcgcatcgct
      721 gatgacacct tcagccgcct gcagaacctc acagagctgt cgctagtacg caactcgctg
      781 gccgccccgc cccttaacct gcccagtgcc cacctgcaga agctctacct gcaggacaat
      841 gccatcagtc acattcccta caacacactg gccaagatgc gggagctgga gaggctggac
      901 ctgtccaaca acaacctcac cacgctgcct cgaggcctgt ttgatgacct ggggaacctg
      961 gcacagctgc tcctcaggaa caacccctgg ttctgtggct gtaacctcat gtggctgcgg
     1021 gactgggtga aggcacgggc cgcagtggtc aatgtgcggg gcctcatgtg ccagggccct
     1081 gagaaggtcc ggggcatggc catcaaagat atcaccagtg agatggatga gtgctttgag
     1141 gcagggtcac agggcagtgc agctaatgca gctgccaaga ccacagccag caaccatgct
     1201 tctgccacca caccccaggg ctctctgttt accctcaagg ccaagaggcc aggactgcgc
     1261 ctccctgact ccaacattga ctaccccatg gccactggag atggcgccaa gacattggtc
     1321 atccaggtga agccactgac agcagactct atccgaatca cgtggaaggc tatgctacct
     1381 gcctcttctt ttcggctcag ttggctgcgc ctgggccata gcccggctgt gggctctatc
     1441 acagagacac tggtgcaggg ggacaagaca gaatacttgc tgacagccct ggagcccaag
     1501 tccacctaca tcatctgtat ggtcaccatg gagactggca acacctatgt ggctgatgag
     1561 acacctgtgt gtgccaaagc agagacagct gatagctatg gccctaccac cacactcaat
     1621 caggaacaga atgctggccc tatggcgggg ctgcccctgg ctggcattat tggtggtgcc
     1681 gtggctcttg tatttctctt cctggtcctg ggagccattt gctggtatgt gcaccgggcc
     1741 ggtgagctgc tgacccgaga gagggtctac aacaggggca gcaggaaaaa ggatgactac
     1801 atggaatcgg ggaccaagaa ggataactcc atcctagaaa tccgaggccc aggactgcag
     1861 atgctcccca tcaacccgta ccgctccaaa gaggagtacg tggtacacac catatttccc
     1921 tccaatggca gcagcctctg caagggagcc cacactattg gctatggcac cacacgaggc
     1981 taccgggaag gtggcatccc tgatgtggac tactcctaca catgaagcta gccgcccccg
     2041 gtgtgatcac gtggctctgt ctagccccct gctacaccag gagccaggaa gaggaactcc
     2101 accgtgactt tccaagtaga aagcaaagtt tggggagggt tggtgatttt gcagaacaca
     2161 acagtgcggt ttaaaaaaaa attaaataca tagaaggcag gagggggatt cagcattgtt
     2221 ggagatgtaa tttataccag atcatgagag ttaaagacta aaaataatct tgcaggaagg
     2281 gttgggttgg attgggattt tttttttcct gaaccagatt gatactatac tacctgtaca
     2341 acatttgtat acacctcgag ctccattcag ggctgtcaga gagaagcaga agccacggag
     2401 cgcccccctc ccccaagcag ccgtccttct ggctgctcac gggtgacaac tcaatgaaag
     2461 gttttcagct tcctcacaaa agagccaggg gaggaaaaga ctttttgcta tggagacagt
     2521 gtcctgaaat ctcttccctg gtcttttcca tgctgttcct ttccagatat atggcgttct
     2581 ccgggatagt ctctcaacaa taccatagtc agttaaaaga gaaaaagtcc agcttttcct
     2641 tccgatgctg agcactgcgg ccccactcac ggagcttctt agaagctctg aggaaagctg
     2701 tggtttccgt gccacgtgga ggtgcatctg tctgcccacc tacggccgag tcctgtgtct
     2761 cagtacggat gggtagatag agctgcgtgt ctgtcagcac ttcttggctc agtccgtgac
     2821 atttgctcag acaatagaat tgcaaaaatc ttgctttctc ctagaaatca ttgaataagt
     2881 aagtagaccg tgtgtaggtg gaggggaggt gcctcagtcc agtggtagga gatcctatgt
     2941 cggctagcac agagccaggc caggccattc ccctctctga tatcgagaaa agcttccctt
     3001 gatgaccagt gccctcatct gtccctcccc caatagatgt catgcttaca atagtgttta
     3061 ctctttctcc tgggacaggt aatttataaa cagggactct ttataaatat atgtgtgcac
     3121 acacacatca gctggctaga cctattgggt ttccatggct gcccaaacaa agcccagaaa
     3181 aaaatttcag aaaatcgctg ggaaacatca gcgtacacac acacacacac acacacacac
     3241 acacacacac acacacacac acacacacac acacagaatc tcagccatgt tcacaccagg
     3301 ggctctgttc tcaagaggaa aaaaatcaga tttctttgtt aaaaaaaaaa aatcagcctc
     3361 ccaaagggta ctgaccaggg ccctcaagag agctaggatt ttattccccc ctgtggaatc
     3421 aatgtcgtta tcatttatca actgacacca cagtgtggtg agccatgaga ttaaaacgat
     3481 gataaaataa tgacagcaga tccggaaagg agggaagagc ggtgcctggg gttctgatgt
     3541 ctgcttcgtc ctgtactcgg ggagcccggg tcaccatctg tcattgcatc gctttgcctt
     3601 gcactggggg aaaaaaaaat catcaaaggg aagatgctgg tctgagggca gctggatgag
     3661 aaggggtcca gctcctgaca ctgatgtttt caaaagacct ctgccactcc atccaaagaa
     3721 aaggcagaaa gaagaggcca ggcagctgcc caaagtgtac ctggtggggc atccacctgc
     3781 tggacattaa agagccaact agcccttcag tgaagagatg aggtagaaag aaacagaccc
     3841 ggcaggtgcc tcagaagagt ggaaagaggc acgagctcct gatcatagcc caagggatca
     3901 tcacaccaaa cggagacccc aacccaccag ccccagggag tggtcaaggg gccatggatc
     3961 actccaaagg agacctttct tcctcttcat cccaagtcat tttccccaca taatgaggtc
     4021 aagagagaaa tgttcctgag cctcaaattc aggtctgtat aaacatgcgc cctggtcccc
     4081 agtgacacta atggtaccct agtcctggca ggctcagagg agaccatctg taagggacag
     4141 gtatgttgag ggcgtgttat cacccctacc ttgacctata acttgccctg taccatagac
     4201 ttactcatgg ccccttccct agttcctacc ccaggaaggg tttggtggtc aagatgacat
     4261 ttaggaacag caggtggcct agggcctggg aggccctttc tggagattca ggagcctgtg
     4321 ggccaaatgc ttgaaacacc agggccatgg taaattcctt tccccaccac acagtaagcc
     4381 tgacccccag gagcctgggc agtcacaggc agaatgtcaa agattgagga ccaaatctgc
     4441 ctcctgctct aaggggctcg ctccatatta tacccagttg gagagcccaa ggctggcact
     4501 gtcccttaaa gagcactaaa tgctgatcag agtgaacact gcccagccat ggccctccaa
     4561 gagtccttcc tgtgtccttt tacctcttct catcttaaca ttttcccagt accctatatt
     4621 ctgtgtgtgt tggggatgga ggaatactgg agactaaatc cagggtctac tgtgcaaggt
     4681 aaacacccca acaccatgct atgttcccag caccacattt gggcgcgtcc tttcagaaag
     4741 cccccaagtg tgacctttgt cccagttctc caaaggagac aggagaacct ggctcttggc
     4801 ctcacataca gtggaaggag ttcaggggac ccagcctcct ctaccctcag aagtgaggga
     4861 agccaggttg acactggaag gccaatggga tcctctctgt gtgcagctga catttccata
     4921 gggagtccgt ggccggctag cctgaccctc acggtttcta accagccaga acaacctccg
     4981 tggcctcagc tccagggagt gtattttgtg gcatttaagg caagtttaaa ctaaaaaaga
     5041 aagccagtga cacttctttg gttaagtggt ttacccttcg tggtaattag acgcagcgat
     5101 tggaatctct ttttctatta catggcaatt ttactttaaa tttcctcttt aaaaaaaaaa
     5161 agggaagaaa aggcaaggaa ggagagaggc atcagggccg gggcatttgc attttgcgaa
     5221 tgaagcctct ggtagactca gctcaggcgt gcggcccaac gtatggaatg cttaagagat
     5281 tactaagaat aaaatctatt aattagtcat actcaattcc gcagacatga cgtgaatcaa
     5341 aagctccctt tcttccctca tctgcatcct cttcctgagg aagcctccat cttccctgaa
     5401 aggctgcctc ctggcctgcc tcctcctccg tggagctcag ccctggccct gtgttgggga
     5461 t
//
