LOCUS       NM_001110138            2879 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus flavin adenine dinucleotide synthetase 1 (Flad1),
            mRNA.
ACCESSION   NM_001110138
VERSION     NM_001110138.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2879)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2879)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107653.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107653.1, SRR8487231.11172.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2879              BC107653.1         1-2879
FEATURES             Location/Qualifiers
     source          1..2879
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2879
                     /gene="Flad1"
                     /note="flavin adenine dinucleotide synthetase 1"
                     /db_xref="GeneID:751787"
                     /db_xref="RGD:1593292"
     exon            1..58
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            59..289
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..1681
                     /gene="Flad1"
                     /EC_number="2.7.7.2"
                     /note="FAD-synthetase"
                     /codon_start=1
                     /product="FAD synthase"
                     /protein_id="NP_001103608.1"
                     /db_xref="GeneID:751787"
                     /db_xref="RGD:1593292"
                     /translation="MASRASELPPGRSVTAGIIIVGDEILKGHTQDTNTYFLCRTLRS
                     LGVQVCRVSVVPDEVATIASEVTSFSRRFTHVLTAGGIGPTHDDVTFEAVALAFGEEL
                     KPHPELQAAIKTLGGEGWEKLSMVPSSARLHYGTDPGTGHPFRFPLVSVRNVYLFPGI
                     PELLRRVLEGLKGLFQNTAVQFHLKELYVAASEGSIAPILSEAQAHFGRRLNLGSYPD
                     WSSNYYQVKLILDSEEKEPLEECLAYLTARLPQGSLIPYLPDAVEKASEAVYKLAESG
                     SCLGKKVAGALQTIETALAQYHLSQICVGFNGGKDCTALLHLFHAAVQRKFPDVPKPL
                     QILYIRSISPFPELEQFLQDTIKRYNLQMLEAEGNMKQALGELQGKHPQLEAVLMGTR
                     RTDPYSCSLHHFSPTDPGWPSFMRINPLLDWTYRNIWEFLRQLFVPYCILYDRGYTSL
                     GSRENTKQNPALKCLSPGGHPVYRPAYLLENEDEERNSRM"
     exon            290..1034
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1182
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1281
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1471
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1545
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..2859
                     /gene="Flad1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctgtgaag ggggcaaaat agaggtggaa tgatacaaga tcagcgatct gaagcttggc
       61 tccctcaacc ccggactgag tactcagggt atggcctcca gtatcctgta gacctgtaga
      121 cctggcggcc tctcagtact tacgacccca atttggggtt ctgagtggct acttgaaagc
      181 cttgcaaaaa agcagagaga gcaggaccat ggcatctagg gcctctgaac tgcccccagg
      241 acgcagcgtg acagcgggca tcatcattgt tggagatgag atccttaagg gacacacgca
      301 agataccaac acttactttc tttgccggac gctgcgctcc ctgggggtcc aggtgtgccg
      361 agtctctgtt gtacctgatg aagtagccac cattgcatcc gaggtcacct cattctccag
      421 gcgcttcact cacgtcctca ccgcgggggg cattggtccc actcatgacg atgtgacctt
      481 tgaggcagtg gcactggctt ttggggagga gctcaaacca caccctgagc tccaagcagc
      541 catcaaaacc ctaggagggg agggttggga gaagctgtcg atggtgccct cctctgcccg
      601 ccttcattac ggtacagatc ccggaactgg ccaccccttc agattcccgc tggtctctgt
      661 ccgaaatgtc tacctcttcc caggaattcc ggagctgctg cgacgagtgt tggagggatt
      721 gaaagggctg ttccaaaaca cagccgtgca attccacctg aaggagttgt atgtggctgc
      781 atcagagggc tctatcgccc ccatcctgtc tgaggcgcag gcccactttg ggcgtaggct
      841 taacctgggt tcctatcctg actggagcag caactactac caggtgaagc tgattctaga
      901 ctccgaggaa aaggagccct tggaggaatg cctggcctat ctgactgcac gtctgcccca
      961 aggatcactc atcccctacc tacccgatgc tgttgagaag gccagtgagg ctgtttacaa
     1021 actcgctgag tcagggtctt gtctggggaa aaaggtagca ggtgccctac agaccattga
     1081 gactgccctg gctcaatacc acctctccca gatctgtgtg ggcttcaatg ggggcaagga
     1141 ctgcaccgcc ctcctgcacc tcttccatgc agctgtgcag agaaaatttc ctgatgttcc
     1201 aaaacctctc cagatcctgt acattcgcag catctcgccc ttccctgagt tggaacagtt
     1261 tctgcaggac accatcaaga ggtataacct acagatgtta gaagctgagg gtaacatgaa
     1321 gcaggccctg ggtgagctcc agggaaagca cccccagctg gaggctgtcc tgatgggcac
     1381 tcgacggact gacccctact cctgtagcct ccaccatttc agccccaccg accctggctg
     1441 gccttcattc atgcgcatca acccgctgct ggactggacc tacagaaaca tctgggaatt
     1501 tctgcggcag ctgtttgtcc catactgcat cctgtatgac agagggtaca catcactggg
     1561 gagtcgggaa aacacaaagc agaatccggc cctgaagtgc ctgagcccag gagggcaccc
     1621 tgtctaccgc ccagcatacc tcctggagaa tgaggatgag gaaaggaact cccgaatgtg
     1681 atctcacaca agcttgggac aagacagagg gaagggggct ggcctggggt aacctgtcat
     1741 gtcagtaaat tgtacctcat gtaccactgt tggtgcctgt tgctctgact gtgccttcct
     1801 gctctgaggt caagggaggc tgccagctcc cgaactggca gtactcactc aggagggggg
     1861 agggggctgg aggaaaggta gaacatacta gaaaggagct tctaggaatg agcctcaatg
     1921 tcaaccaaag gagaggaggc aaccaggaag agcactgcct gctcgcaagg gaagctgggc
     1981 tttcctggct gtggaggata aaggatgggg tggccaagcc ctcccttcta accaccgtcc
     2041 ccatctgaaa ggctgactca gcctgctccg aggccccaga accttctttt gctagaccct
     2101 agagcctttg tttttagtca tgaggcctga gggggtgggg acagtggata aaaggtccca
     2161 aaggcagcgt ccacacccct ctgccgagct gctgtccaca tgaagccacc gatgcagccc
     2221 ctgacccagg ccctgccctt ctctctgaga gatgcccttc aaggcactgg tctccgcgtg
     2281 cctgtcatta agatgggcac agggtgggag ggcatgtatc gaaccctgaa ggaagtcgcc
     2341 tacatccttc tttgttgctg gtgtatcaag gaactgctgg attaatggtg gcggggaaca
     2401 cctcctgtca tccctgacac caagacctgc atcactcagg tggggagggg aggggagagt
     2461 gtcaggaggt gtggctgcag cttctgggct ggaacctgca gctcagctct cccctctttt
     2521 ctatagccct aagactcctg gagcctgccg gccttcacca aggatggagc gcaaacaact
     2581 gagagggaac catgaacctt gctttgagcc gtttatgcgt ctgacctgcc tcatcctggg
     2641 gcatgtatcc tgggctcctg tctctggtgt ggttctggta ctcatgagct tggcttgccg
     2701 cctaagactc cagtgagact acagcaggat ctaatattct ccaaaattgg tacagtgacc
     2761 ccaccaaccc acacacttga agaaccagga atggactgcc cctaagatac ctggtaatca
     2821 ctcaactata taataaatag gccttgaggc caaaagctca aaaaaaaaaa aaaaaaaaa
//
