LOCUS       NM_001002818            1300 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus FKBP prolyl isomerase like (Fkbpl), mRNA.
ACCESSION   NM_001002818
VERSION     NM_001002818.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Yakkundi,A., Bennett,R., Hernandez-Negrete,I., Delalande,J.M.,
            Hanna,M., Lyubomska,O., Arthur,K., Short,A., McKeen,H., Nelson,L.,
            McCrudden,C.M., McNally,R., McClements,L., McCarthy,H.O.,
            Burns,A.J., Bicknell,R., Kissenpfennig,A. and Robson,T.
  TITLE     FKBPL is a critical antiangiogenic regulator of developmental and
            pathological angiogenesis
  JOURNAL   Arterioscler Thromb Vasc Biol 35 (4), 845-854 (2015)
   PUBMED   25767277
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC086532.1.
            
            On Nov 22, 2004 this sequence version replaced NM_001002818.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086532.1, FQ231484.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1300
                     /gene="Fkbpl"
                     /note="FKBP prolyl isomerase like"
                     /db_xref="GeneID:406168"
                     /db_xref="RGD:1303227"
     exon            1..113
                     /gene="Fkbpl"
                     /inference="alignment:Splign:2.1.0"
     exon            114..1272
                     /gene="Fkbpl"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1247
                     /gene="Fkbpl"
                     /EC_number="5.2.1.8"
                     /note="WISp39; WAF-1/CIP1 stabilizing protein 39; FK506
                     binding protein-like"
                     /codon_start=1
                     /product="FK506-binding protein-like"
                     /protein_id="NP_001002818.1"
                     /db_xref="GeneID:406168"
                     /db_xref="RGD:1303227"
                     /translation="METSLISPMKENNTAQPQQREENTQQNLNAAVPIKQQSPGLLPE
                     ALEVGVKPDPASQILATQEIENPVAGFEGDSDKFHISTDEMAEHLQASDLWYCPDGSF
                     VKKIIVHGHGLDKPKLGSKCRVLALGFPFGSGMPEGWTELTIGTGQWREKTWGELTEK
                     CLESMRQGEEAKIHLPGSSTPLAKLRLDSFTNGRDSWELEAVEKEALAKEEHRRGTEL
                     FRAGNPQGAARCYGRALRLLLTLPPPGPPERTILHANLAACQLLLGHPQLAAQSCDRV
                     LEREPGHLKALYRRGVAQAALGDLDKATADLKKVLAVDPKNRAAKEELGKVVIQGKIQ
                     DAGLARGLRKMFS"
ORIGIN      
        1 gagggctgat tgagacgctc agctgctccc aggctgctcc tccaggcgcc aacaccgtac
       61 tcaatgcaag aattgtgact tgggtcatcc tgccatgccc cctggcctct caggtctgaa
      121 ctacaattga cccgtcgtca ctttgcagac taaactgttc cttcctttat ctcatctact
      181 gtggaaggga tcaggagatc caaatggaga cctcacttat cagcccaatg aaagagaaca
      241 acaccgcaca accgcagcag cgggaagaga acacccagca aaacctaaat gcagccgttc
      301 cgattaagca gcagtcccca ggtcttctcc ctgaagccct ggaggtggga gtgaaaccag
      361 atccagccag tcaaatttta gcgactcaag agattgaaaa tcccgtagct ggatttgaag
      421 gtgactctga taaatttcac atctccaccg atgagatggc agagcacctt caagcttctg
      481 atctttggta ctgccctgat gggagttttg taaagaagat catagttcat ggccacggct
      541 tagacaaacc caagctaggc tccaaatgcc gagtgttggc tttggggttt ccttttggat
      601 ctgggatgcc agagggctgg acagaactaa ccataggcac agggcaatgg agggaaaaaa
      661 catgggggga actcacagaa aaatgcctgg agtcgatgcg tcaaggtgag gaagccaaga
      721 ttcaccttcc tggatcctct acacctcttg ctaagctcag actggattcc ttcaccaatg
      781 gccgggactc ctgggagttg gaggctgtgg agaaggaggc tctggccaaa gaagaacaca
      841 gaaggggcac cgaattgttt cgagctggga accctcaagg ggctgcccga tgctacggac
      901 gggctctccg gctgctgctg acgttgcccc cacccggccc acctgaacga actattcttc
      961 atgccaatct ggcagcctgt cagttgctgc taggacaccc ccagttggca gcccagagct
     1021 gtgaccgagt gctggagcgg gagccgggcc atttaaaggc gttataccga agaggggttg
     1081 ctcaggctgc cctcggggac ttggataaag caactgctga tctcaagaaa gttctagcag
     1141 tagatcccaa aaaccgtgcc gcgaaagagg agctggggaa ggtggtcatt cagggaaaga
     1201 tacaggatgc agggctggct cgggggctgc gcaagatgtt tagctgatta aaaagttaaa
     1261 ttttaaaaga gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
