LOCUS       NM_001037180            1679 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus FKBP prolyl isomerase 8 (Fkbp8), mRNA.
ACCESSION   NM_001037180 XM_214316
VERSION     NM_001037180.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1679)
  AUTHORS   Mali,G.R., Yeyati,P.L., Mizuno,S., Dodd,D.O., Tennant,P.A.,
            Keighren,M.A., Zur Lage,P., Shoemark,A., Garcia-Munoz,A.,
            Shimada,A., Takeda,H., Edlich,F., Takahashi,S., von Kreigsheim,A.,
            Jarman,A.P. and Mill,P.
  TITLE     ZMYND10 functions in a chaperone relay during axonemal dynein
            assembly
  JOURNAL   Elife 7, e34389 (2018)
   PUBMED   29916806
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1679)
  AUTHORS   Li,H., Zhang,C., Cui,H., Guo,K., Wang,F., Zhao,T., Liang,W., Lv,Q.
            and Zhang,Y.
  TITLE     FKBP8 interact with classical swine fever virus NS5A protein and
            promote virus RNA replication
  JOURNAL   Virus Genes 52 (1), 99-106 (2016)
   PUBMED   26748656
REFERENCE   3  (bases 1 to 1679)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 1679)
  AUTHORS   Cho,A., Ko,H.W. and Eggenschwiler,J.T.
  TITLE     FKBP8 cell-autonomously controls neural tube patterning through a
            Gli2- and Kif3a-dependent mechanism
  JOURNAL   Dev Biol 321 (1), 27-39 (2008)
   PUBMED   18590716
REFERENCE   5  (bases 1 to 1679)
  AUTHORS   Wong,R.L., Wlodarczyk,B.J., Min,K.S., Scott,M.L., Kartiko,S.,
            Yu,W., Merriweather,M.Y., Vogel,P., Zambrowicz,B.P. and
            Finnell,R.H.
  TITLE     Mouse Fkbp8 activity is required to inhibit cell death and
            establish dorso-ventral patterning in the posterior neural tube
  JOURNAL   Hum Mol Genet 17 (4), 587-601 (2008)
   PUBMED   18003640
REFERENCE   6  (bases 1 to 1679)
  AUTHORS   Okamoto,T., Nishimura,Y., Ichimura,T., Suzuki,K., Miyamura,T.,
            Suzuki,T., Moriishi,K. and Matsuura,Y.
  TITLE     Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
  JOURNAL   EMBO J 25 (20), 5015-5025 (2006)
   PUBMED   17024179
  REMARK    Erratum:[EMBO J. 2006 Nov 29;25(23):5634]
REFERENCE   7  (bases 1 to 1679)
  AUTHORS   Kang,C.B., Tai,J., Chia,J. and Yoon,H.S.
  TITLE     The flexible loop of Bcl-2 is required for molecular interaction
            with immunosuppressant FK-506 binding protein 38 (FKBP38)
  JOURNAL   FEBS Lett 579 (6), 1469-1476 (2005)
   PUBMED   15733859
REFERENCE   8  (bases 1 to 1679)
  AUTHORS   Bulgakov,O.V., Eggenschwiler,J.T., Hong,D.H., Anderson,K.V. and
            Li,T.
  TITLE     FKBP8 is a negative regulator of mouse sonic hedgehog signaling in
            neural tissues
  JOURNAL   Development 131 (9), 2149-2159 (2004)
   PUBMED   15105374
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107454.1.
            
            On Nov 18, 2005 this sequence version replaced XM_214316.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107454.1, SRR8487227.303595.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1679
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1679
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /note="FKBP prolyl isomerase 8"
                     /db_xref="GeneID:290652"
                     /db_xref="RGD:1308670"
     exon            1..52
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            53..339
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1289
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /EC_number="5.2.1.8"
                     /note="rotamase; PPIase FKBP8; FK506-binding protein 8;
                     FK506 binding protein 8, 38kDa"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase FKBP8"
                     /protein_id="NP_001032257.1"
                     /db_xref="GeneID:290652"
                     /db_xref="RGD:1308670"
                     /translation="MASWAEPSEPAAQLLCGAPLLEGFEVLDGVDDAEEEDDLSGLPP
                     LEDMGQPTVEEAEQPGALAREFLAATEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPT
                     GSSRPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDCDVIQALDLSVPLMHVGETAM
                     VTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQERVALANRKREC
                     GNAHYQRADFVLAANSYDLAIKAITSNAKVDMTCEEEEELLQLKVKCLNNLAASQLKL
                     DHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIH
                     AELSKLVKKRAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGG
                     VALSVVIAARN"
     exon            340..509
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            510..598
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            599..819
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            820..992
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1070
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1202
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1666
                     /gene="Fkbp8"
                     /gene_synonym="FKBP-8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgggggtgg ggaggggggc acaggacccc aagcggggtc cccaagccgc agggccagtt
       61 cctgatcccc cagcagcatg gcgtcttggg ccgagccctc tgagcctgct gcccagctac
      121 tttgtggggc cccactcctg gagggctttg aggtgcttga tggggttgat gatgcagagg
      181 aggaagatga cctaagtggg ttgccaccac tagaggatat gggacagcct acggtggagg
      241 aggctgagca gcctggagcc ctagctcggg agttcctggc agccacagag cctgagccag
      301 ccccagcccc cgccccggaa gagtggctgg acattctggg gaacggattg ctgcgtaaga
      361 agacactggt cccaggccca acaggctcta gccgcccact caagggccag gtggtgaccg
      421 tacacctgca gatgtccctg gagaatggca cccgtgtgca agaggagccc gaactggctt
      481 tcacgcttgg agactgcgat gttatccagg ccctggacct cagcgtcccg ctcatgcatg
      541 tgggcgagac agcaatggtc accgctgact ccaagtactg ctacggtccc cagggcagca
      601 ggagcccata catccccccc catgcagccc tgtgcctgga agtcaccctg aagacagcag
      661 aggatggacc tgacctggag atgctgagtg ggcaggagcg cgtggccctg gccaaccgca
      721 agcgggagtg tggcaatgcc cactaccagc gtgctgactt tgtgctggct gccaactcct
      781 atgacctggc catcaaggcc atcacctcca acgccaaagt ggacatgact tgtgaggagg
      841 aggaggagct gctacagctg aaggtcaagt gtctgaacaa ccttgcggca tcgcagctaa
      901 agctggacca ctaccgagca gcactgcgct cctgtagcca ggtgctggag caccagccag
      961 acaacatcaa ggcactgttc cgcaagggca aggtgctggc tcagcagggt gaatacagtg
     1021 aggccatccc catcctgagg gcggccctga agctggagcc ttccaacaag acgatccatg
     1081 cggagctctc aaagctggta aagaagcgtg ctgcacagcg gagcacagag actgccctgt
     1141 accgaaagat gctaggcaac cccagccggc tgcctgccaa gtgtccgggc aagggtgcct
     1201 ggtccatccc gtggaaatgg ctgtttgggg caactgccgt ggccctgggg ggcgtggctc
     1261 tctctgtggt cattgctgcc aggaactgac tgtccccctg catacctgga ccccaacctg
     1321 tgctccccaa ctcccccagg ctccctgtcc actgccctcc ctggccgaga cacctcctat
     1381 gggttggggg agcaaggatt gagggtcgca caccccaaca agcaggaaag actgagaccc
     1441 tgaaaggggg catggggtac agcccagagg gaggggccct gttcctccag acccagttgt
     1501 ctctctccca caaccctgtt gtcctctggg gtcaggcctc agctggggca gcctcagttt
     1561 tccctcagta ggcctggggg cagcactacc attccttcct gcccgcctgc accctctgtc
     1621 caggcttccc cacagtgatt taaataaagc ctcaccccac accctaaaaa aaaaaaaaa
//
