LOCUS       NM_145682               4338 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus filamin A interacting protein 1 (Filip1), mRNA.
ACCESSION   NM_145682 XM_346831
VERSION     NM_145682.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Yagi,H., Nagano,T., Xie,M.J., Ikeda,H., Kuroda,K., Komada,M.,
            Iguchi,T., Tariqur,R.M., Morikubo,S., Noguchi,K., Murase,K.,
            Okabe,M. and Sato,M.
  TITLE     Filamin A-interacting protein (FILIP) is a region-specific
            modulator of myosin 2b and controls spine morphology and NMDA
            receptor accumulation
  JOURNAL   Sci Rep 4, 6353 (2014)
   PUBMED   25220605
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  AUTHORS   Sato,M. and Nagano,T.
  TITLE     Involvement of filamin A and filamin A-interacting protein (FILIP)
            in controlling the start and cell shape of radially migrating
            cortical neurons
  JOURNAL   Anat Sci Int 80 (1), 19-29 (2005)
   PUBMED   15794127
  REMARK    Review article
REFERENCE   3  (bases 1 to 4338)
  AUTHORS   Nagano,T., Morikubo,S. and Sato,M.
  TITLE     Filamin A and FILIP (Filamin A-Interacting Protein) regulate cell
            polarity and motility in neocortical subventricular and
            intermediate zones during radial migration
  JOURNAL   J Neurosci 24 (43), 9648-9657 (2004)
   PUBMED   15509752
  REMARK    GeneRIF: Results suggest that the amount of Filamin A helps
            migrating neurons determine their mode of migration, multipolar or
            bipolar, before entering the cortical plate and that FILIP is
            responsible, at least in part, for Filamin A content.
REFERENCE   4  (bases 1 to 4338)
  AUTHORS   Nagano,T., Yoneda,T., Hatanaka,Y., Kubota,C., Murakami,F. and
            Sato,M.
  TITLE     Filamin A-interacting protein (FILIP) regulates cortical cell
            migration out of the ventricular zone
  JOURNAL   Nat Cell Biol 4 (7), 495-501 (2002)
   PUBMED   12055638
  REMARK    GeneRIF: FILIP interacts with Filamin A, an indispensable
            actin-binding protein that is required for cell motility (filamin
            A)
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_145682.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB055759.1, SRR26360194.539149.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676786 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                JAXUCZ010000008.1  89802704-89802771   c
            69-347              JAXUCZ010000008.1  89739264-89739542   c
            348-521             JAXUCZ010000008.1  89699019-89699192   c
            522-700             JAXUCZ010000008.1  89685253-89685431   c
            701-3506            JAXUCZ010000008.1  89658003-89660808   c
            3507-4338           JAXUCZ010000008.1  89655699-89656530   c
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..4338
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /note="filamin A interacting protein 1"
                     /db_xref="GeneID:246776"
                     /db_xref="RGD:628597"
     exon            1..68
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
     exon            69..347
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..3713
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /note="filamin-interacting protein L-Filip;
                     filamin-interacting protein S-Filip"
                     /codon_start=1
                     /product="filamin-A-interacting protein 1"
                     /protein_id="NP_663715.2"
                     /db_xref="GeneID:246776"
                     /db_xref="RGD:628597"
                     /translation="MRSRNQGGESSSNGHVSCPKSSIISSDGGKGPSEDAKKNKANRK
                     EEDVMASGTIKRHLKPSGESEKKTKKSVELSKEDLIQLLSIMEGELQAREDVIHMLRT
                     EKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKET
                     YRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEK
                     AYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLRE
                     EEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKL
                     VGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGK
                     DEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQ
                     LHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLV
                     DERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYS
                     LTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPE
                     DNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE
                     IKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQL
                     SQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSKRYSRALRPSGNGRRMVDVP
                     VASTGVQTEAVCGDAAEEETPAVFIRKSFQEENHIMSNLRQVGLKKPMERSSVLDRYP
                     PAANELTMRKSWIPWMRKRENGPSTPQEKGPRPNQGAGHPGELVLAPKQGQPLHIRVT
                     PDHENSTATLEITSPTSEEFFSSTTVIPTLGNQKPRITIIPSPNVMSQKPKSADPTLG
                     PERAMSPVTITTISREKSPEGGRSAFADRPASPIQIMTVSTSAAPTEIAVSPESQEVP
                     MGRTILKVTPEKQTVPAPVRKYNSNANIITTEDNKIHIHLGSQFKRSPGPAAEGVSPV
                     ITVRPVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSVSG
                     QDGSSQRPTPTRIPMSKGMKAGKPVVAASGAGNLTKFQPRAETQSMKIELKKSAASST
                     ASLGGGKG"
     exon            348..521
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
     exon            522..700
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
     exon            701..3506
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
     exon            3507..4338
                     /gene="Filip1"
                     /gene_synonym="Filip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccactgggtt cttcaaggga taaaccagcg gcgaaagaac acaccattgg ttaaggagtc
       61 gacaacaggt gggaatgaga tcacgaaatc aaggtggaga aagttcatct aacgggcatg
      121 tctcctgccc caagtcctcc atcatcagca gtgatggtgg taagggcccc tcagaagatg
      181 caaaaaagaa caaggccaat cggaaggagg aggatgtcat ggcttccgga actatcaaaa
      241 ggcacctcaa accatctgga gaaagtgaga aaaagactaa gaagtctgtg gagttatcca
      301 aggaggacct catccagctc ctgagtatca tggaagggga gttgcaggct cgagaagatg
      361 tcatccacat gctgaggaca gagaaaacca agcccgaggt tctggaggca cactatggat
      421 ctgcagaacc tgagaaagtg cttcgggtcc tgcaccgaga tgccatcctt gctcaagaga
      481 agtccatagg agaagacgtc tatgagaaac ctatctcaga gctggacaga ctggaggaaa
      541 agcagaagga gacgtaccgc cgcatgctag agcagctgct gctggctgag aagtgtcaca
      601 ggcgcaccgt gtacgagctg gagaacgaga agcacaagca cactgactac atgaacaaga
      661 gcgacgactt caccaacctg ctggagcagg agcgagagag gttgaaaaag ctccttgaac
      721 aagaaaaagc ttaccaagcc cgcaaagaaa aggaaaacgc taagcggctc aacaaacttc
      781 gagatgagct tgtgaagctc aagtccttcg ccctcatgtt ggtggacgag aggcagatgc
      841 acatcgagca actgggcctg cagagtcaga aagtccagga cctcactcag aagctgaggg
      901 aggaggaaga aaaactcaaa gcggtcactt acaaatccaa ggaagaccgc cagaagctgc
      961 tcaagttaga agtggacttc gaacacaagg cctcgaggtt ttcccaggag cacgaagaga
     1021 tgaacgccaa attggcgaat caagaatctc acaaccggca acttcgactc aaactggttg
     1081 gcttatcgca aaggattgag gagctggaag agaccaataa aagccttcag aaggcagagg
     1141 aagagctcca ggagctgaga gagaaaattg ccaaagggga atgtggaaac tccagtctca
     1201 tggcggaagt ggagagtctg cgcaagcgcg tgcttgagat ggagggcaag gatgaagaga
     1261 tcacgaagac tgaggcccag tgccgggagc tgaagaagaa gctccaagag gaagaacacc
     1321 acagcaagga acttagacta gaagtggaga agctgcagaa gaggatgtct gagctggaga
     1381 agctggagga agcgttcagc cggagtaagt cggaatgcac ccagctccat ctgaacctgg
     1441 agaaggagaa gaacctaacc aaagacctgc tgaacgagct ggaggtggtc aagagtcgag
     1501 ttaaagaact cgaatgctcc gagagtagac tggagaaggc cgagttaagc ctcaaagatg
     1561 accttacaaa gctgaagtcc ttcactgtga tgctggtgga tgagaggaaa aatatgatgg
     1621 agaaaataaa gcaagaagag aggaaagtgg atgggttgaa taaaaacttt aaggtggagc
     1681 agggaaaagt catggatgtg acggaaaagc taatcgagga aagcaagaag cttttaaaac
     1741 tcaaatctga aatggaggaa aaggtgtaca gtctgacaaa ggagagggat gagctgatgg
     1801 gtaaactgag gagcgaagaa gaaaggtcct gtgaactgag ctgcagtgta gacttactaa
     1861 agaagcggct tgatggcata gaggaggtag aaagggaaat aaaccgaggt aggtcgtgca
     1921 aggggtctga gttcacctgc ccggaagaca ataagatcag agaactaacg cttgaaatcg
     1981 agagactgaa gaaacggctc cagcagttgg aggtggtgga gggggacttg atgaagaccg
     2041 aggacgaata tgaccagttg gagcagaagt tcagaaccga gcaggataag gcaaacttcc
     2101 tctcccagca gctcgaggaa atcaaacacc aaatggccaa gcacaaagcc atagagaaag
     2161 gggaggccgt gagccaggaa gccgaactgc gacacaggtt tcggctggag gaggctaaaa
     2221 gtcgtgattt acaggccgag gtgcaggctc tcaaggagaa gatccacgag ctgatgaaca
     2281 aggaagacca gctgtctcag ctccaagtcg actattcggt ccttcagcaa agatttatgg
     2341 aagaagaaac taagaacaag aacatgggga gggaggtcct caatctgacc aaggagctag
     2401 agctttccaa gcgctacagc cgagctctca ggccgagtgg gaacggccga aggatggtgg
     2461 acgtgcctgt ggcctccact ggggtgcaga ccgaggcggt gtgcggggat gctgcggagg
     2521 aggagacccc ggctgtgttc attcgcaaat ccttccagga ggaaaatcac atcatgagta
     2581 atcttcgaca ggtaggcctg aagaaaccca tggaacggtc ctcggtcctc gacaggtatc
     2641 ccccagcagc gaatgagctc accatgagga agtcttggat tccttggatg agaaaaagag
     2701 aaaacggtcc ttccactccg caggagaaag ggcccaggcc aaaccagggt gcagggcacc
     2761 ccggggagct ggtcctagca ccaaagcagg gccagcccct acacatccgt gtgacaccag
     2821 atcatgagaa cagcactgcc accctggaga tcacaagccc cacatctgaa gagtttttct
     2881 ctagtaccac cgtcattcct accttaggca accagaaacc aagaataacc attattccat
     2941 cacccaatgt catgtcgcaa aagcccaaaa gtgcagatcc tactctcggc ccagaacgag
     3001 ccatgtcccc tgtcacgatt actactattt ccagagagaa gagcccggaa ggtggaagga
     3061 gcgcctttgc cgacaggcct gcatccccca tccaaatcat gacggtgtca acatctgcag
     3121 ctcccactga aatcgctgtc tctcctgaat ctcaggaagt gcctatggga aggactatcc
     3181 tcaaagtcac cccggaaaaa caaactgttc cagcccccgt gcggaagtac aactccaatg
     3241 ctaatatcat caccacggaa gacaataaaa ttcacattca cctgggttct cagtttaagc
     3301 gatctcctgg gcctgccgct gaaggcgtga gcccagttat caccgtccgg cctgtcaacg
     3361 tgacagcgga gaaggaggtt tctacaggca cagtccttcg ctctcccagg aaccacctct
     3421 cttcaagacc cggtgctagc aaagtgacca gcactataac tataaccccg gtcacaacgt
     3481 catccacacg aggaacccaa tcagtgtcag gacaagatgg gtcatctcag cggcctaccc
     3541 ccacccgcat tcctatgtca aaaggtatga aagctggaaa gccagtagtg gcagcctcag
     3601 gagcaggaaa tctgaccaaa ttccagcctc gagctgagac tcagtctatg aaaatagagc
     3661 tgaagaaatc tgcagccagc agcactgcct ctcttggagg ggggaagggc tgagggcagt
     3721 ggctaagggg gtatgttgta aggatgctac tgctgcagtg gaaacaaacc ttcctctgtg
     3781 ccaacccttt ccttgtacta ctaatttaag ttttaaatat cttgtttata aaataaccat
     3841 ttaatagcca tgcacccccc tcccattttg tgcatctgtt tcaatgcagg ggaatagaat
     3901 taattagcag aatttctgtt tgctgaatgt tctgttgaag atgttggtcc agttcagttt
     3961 tacttctagc atgtggcccc attcaaggta gctcacgagt tgtgaagccc tcaatatcgt
     4021 caccggagag atttgaggac cacattacat atgctcccaa aggctggctc ccaattttcc
     4081 taattgtaag ccaactttaa tagactcagt tctgtgattt ttttttccaa aaaaaaatat
     4141 tttgaaatag gacagagttt aacagttgtc attttgcact atcaagccat gagtttgata
     4201 tatgggttat aagaaaagaa tactttcaga gctatcacag ggtctctaaa cttttggaaa
     4261 aacaaaagcc cctaatatga cctcaggaaa caatttgaac atgaaataaa atggaaatga
     4321 actgtggaat cttaaaaa
//
