LOCUS       NM_001106484            3388 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus fidgetin, microtubule severing factor (Fign),
            mRNA.
ACCESSION   NM_001106484 XM_001055272 XM_001055328 XM_229979
VERSION     NM_001106484.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Ma C, Wang J, Tu Q, Wu R, Lai X, Lin G, Dong Z, Guan T, Qiang L,
            Liu Y and Liu M.
  TITLE     Fidgetin impacts axonal growth and branching in a local mTOR signal
            dependent manner
  JOURNAL   Exp Neurol 361, 114315 (2023)
   PUBMED   36586551
  REMARK    GeneRIF: Fidgetin impacts axonal growth and branching in a local
            mTOR signal dependent manner.
REFERENCE   2  (bases 1 to 3388)
  AUTHORS   Yang Y, Mahaffey CL, Berube N and Frankel WN.
  TITLE     Interaction between fidgetin and protein kinase A-anchoring protein
            AKAP95 is critical for palatogenesis in the mouse
  JOURNAL   J Biol Chem 281 (31), 22352-22359 (2006)
   PUBMED   16751186
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473949.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001055272.1, XM_001055328.1, XM_229979.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMEA5760400 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3388
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q21"
     gene            1..3388
                     /gene="Fign"
                     /note="fidgetin, microtubule severing factor"
                     /db_xref="GeneID:295649"
                     /db_xref="RGD:1308174"
     exon            1..169
                     /gene="Fign"
                     /inference="alignment:Splign:2.1.0"
     exon            170..339
                     /gene="Fign"
                     /inference="alignment:Splign:2.1.0"
     CDS             315..2594
                     /gene="Fign"
                     /codon_start=1
                     /product="fidgetin"
                     /protein_id="NP_001099954.1"
                     /db_xref="GeneID:295649"
                     /db_xref="RGD:1308174"
                     /translation="MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRG
                     HLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGR
                     KNDSEPWQSSLNSEAVYPMNCVPDVITASKAGVSSALPPVDVSASIGSSPGVASNLTE
                     PSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPTPALPSPHPSPLHSSG
                     LLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLP
                     SGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYG
                     NYSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSLAFKPTKQLMPSEQQRKFS
                     SQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDDHRQLLAHPIQGPGLRAA
                     TSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLR
                     SDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKI
                     IHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQI
                     VVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLV
                     QRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPITYQDFENAFCKIQPSI
                     SQKELDMYVEWNKMFGCSQ"
     exon            340..3388
                     /gene="Fign"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttgggtttg aaattccaac atggcagagg ctgcagtccg tcttcccttc aaaaacttgg
       61 aatgatttca aatcataggc accttcactt aaccctagct tccattcatc agcaaacaca
      121 tcggatcgat gctacgctaa cctatcggga gctcgctctg cgcgtccagg ttaaatgagt
      181 acctgacgaa agggcccacg tttcaaggca gtgacatttg atagctgaga ggaaaagtgg
      241 ctttaatgaa aagcaacctt tggaattcct gcttgtgaga aatccaattc agctttttgt
      301 gctaccagca agaaatgatc agtagcacca gtgtttatgg cttgaagatg cagtggacgc
      361 cggagcatgc ccagtggcca gaacagcact ttgatatcac ctcgactact cggtctcccg
      421 cccacaaagt tgaagcctat agaggtcatt tgcaacgcac ctaccagtat gcctgggcga
      481 atgatgacat atctgctctg actgcatcca accttctgaa aaaatatgca gagaaatatt
      541 ctggcatttt ggaaggtccc gtagaccgac ctgtactcag caattattca gacacaccgt
      601 cgggactagt gaatggtcgg aaaaatgata gcgaaccctg gcagtcttcc ttgaattcag
      661 aagccgttta tcctatgaac tgtgttccgg atgtcatcac cgccagcaaa gctggtgtca
      721 gttcagccct ccctccagta gatgtctcgg caagtatagg aagctcccct ggggtggcca
      781 gcaacctgac agaaccaagt tactcaagta gtacctgtgg aagccacaca gtacctagtc
      841 ttcatgcggg gctcccgtct caggaatatg ctccaggata caacggatcg tatttgcatt
      901 ctacttacag cagccagccc acacctgcac ttccttcgcc tcatccatcc ccgttgcata
      961 gctctgggct cctgcagcca ccaccccctc ctcctcctcc acccgccctg gtcccaggct
     1021 acaatgggac ttccaatctc tccagttaca gctatccctc tgctagctat cctcctcaga
     1081 ctgccgtggg gtctgggtac agccctggtg gagcaccccc tcctccttcc gcctacctgc
     1141 cttcaggaat tcctgcgccc acccctttgc cccccactac tgttcctggc tacacctacc
     1201 aaggtcatgg tttgacaccc atcgcaccct ctgctctgac caacagttcg gcaagttctc
     1261 tcaaaaggaa agctttctat atggcagggc aaggagacat ggactccagt tacggaaatt
     1321 acagctatgg ccaacagaga tcaacgcaga gtcctatgta ccgaatgccc gacaacagca
     1381 tttcaaactc gaatcggggg aatggctttg acagaaatgc tgaaacatca tccttagcat
     1441 ttaagccaac aaagcagctg atgccctctg agcagcaaag gaaattcagc agccagtcca
     1501 gtagggctct gacccctcct tcctatagta ctgctaaaaa ttcattggga tcaagatcga
     1561 gtgaatcctt tgggaagtat acgtcgccag tcatgagtga gcacggggac gaccatcggc
     1621 agctcctcgc tcatccaata caaggtccgg gactccgtgc agctacctca tccaaccact
     1681 ccgtggacga gcaactgaag aatactgaca cgcacctcat tgacctggtc accaatgaga
     1741 tcatcaccca aggacctcct gtggactgga gcgacatagc tggtcttgac ctggtgaagg
     1801 cggttattaa ggaggaggtt ttgtggccag tgttgaggtc agatgcgttc agtgggctga
     1861 cagccttacc taggagcatc cttctctttg gacctcgggg tacaggcaaa acactattgg
     1921 gcagatgcat agccagtcag ctgggggcca cgtttttcaa aattgctggt tccggactcg
     1981 ttgcaaagtg gctaggagaa gcggagaaaa ttatccacgc ctcttttctt gtggccaggt
     2041 gtcgccagcc ctcggtgatt tttgttagtg acattgacat gcttctctcc tctcaagtga
     2101 gtgaggaaca cagtccagtg agtcggatga gaaccgaatt tctgatgcag ctggacactg
     2161 tactgacttc ggctgaggac caaatcgtag tcatttgtgc caccagtaaa ccagaagaaa
     2221 tagacgaatc tctccggagg tacttcatga aaagactttt aatcccactt cctgacagca
     2281 cagcgaggca ccagataata gtacaactgc tctcacagca caattactgt ctcaatgaca
     2341 aggagtttgc actgctcgtc cagcgcacag aaggcttttc tggactagac gtggctcatt
     2401 tgtgccagga agcagcagtg ggtcctctcc atgctatgcc agctacagac ctttcagcca
     2461 ttatgcccag ccagttaagg cccattacat atcaagactt tgaaaatgca ttctgcaaga
     2521 ttcagcctag catatctcaa aaagagcttg atatgtatgt tgaatggaac aaaatgtttg
     2581 gttgcagtca gtgataacat ctttaaaaaa atgtaatgaa tgttggcaca cacataaaac
     2641 ctgctccata gggaatagag cccctttcca gtagtgtttc aatggctaag ggtactgggg
     2701 aagacaacga ttatgttgca tctttagagt caggggtagc tttggaggaa gcaggcctca
     2761 gatgagagcc tgtgatttgg aagccccagc tgacagaaag catatacaat gtggatgctc
     2821 agatcggttc aagctagaca acgctcaccg agaagcaagg tgcaagcgtg ttgatttcag
     2881 aaggacatga acctcgtgtg ttgattccat tctgctgttc tcgagattta gttgctgtca
     2941 agtgcctgga gtggtacttt atttttttgt ttgcctcaca attacattgg tggcatgtgc
     3001 taatataaag agctttaact tcaaacatta ttggactaaa gagatgaacg gttgtgttac
     3061 aacagaaaac cagatttttt tggccatttt aagagcaaca gtattcctca atcctgtctg
     3121 ttctgcagtg ttagctaaga acaggtaaaa cagggtaacg gtaatctgga ccttaatttc
     3181 tgcagttcat ttcttttaat gttcttgtct gcaaaaactc aggaaagtga ttgtgatttg
     3241 tacagtacct caaaggaatg tgttaaaagc actatgtact gctgagagta atagggtagg
     3301 cttcaatgtt actttatatt aaaatgtatg tttacctcaa caattggaga atagcaagga
     3361 aaattacttt gaatgtatcc agaaaaag
//
