LOCUS       NM_172334               1209 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus FGF1 intracellular binding protein (Fibp), mRNA.
ACCESSION   NM_172334
VERSION     NM_172334.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1209)
  AUTHORS   Frobel,J., Cadeddu,R.P., Hartwig,S., Bruns,I., Wilk,C.M.,
            Kundgen,A., Fischer,J.C., Schroeder,T., Steidl,U.G., Germing,U.,
            Lehr,S., Haas,R. and Czibere,A.
  TITLE     Platelet proteome analysis reveals integrin-dependent aggregation
            defects in patients with myelodysplastic syndromes
  JOURNAL   Mol Cell Proteomics 12 (5), 1272-1280 (2013)
   PUBMED   23382103
REFERENCE   2  (bases 1 to 1209)
  AUTHORS   Kuo,H.S., Tsai,M.J., Huang,M.C., Huang,W.C., Lee,M.J., Kuo,W.C.,
            You,L.H., Szeto,K.C., Tsai,I.L., Chang,W.C., Chiu,C.W., Ma,H.,
            Chak,K.F. and Cheng,H.
  TITLE     The combination of peripheral nerve grafts and acidic fibroblast
            growth factor enhances arginase I and polyamine spermine expression
            in transected rat spinal cords
  JOURNAL   Biochem Biophys Res Commun 357 (1), 1-7 (2007)
   PUBMED   17418108
  REMARK    GeneRIF: Thus, in addition to enhancing the expression of Arg I and
            spermine in repaired spinal cords, our treatment may recruit
            activated macrophages and create a more favorable environment for
            axonal regrowth.
REFERENCE   3  (bases 1 to 1209)
  AUTHORS   Kolpakova,E., Wiedlocha,A., Stenmark,H., Klingenberg,O.,
            Falnes,P.O. and Olsnes,S.
  TITLE     Cloning of an intracellular protein that binds selectively to
            mitogenic acidic fibroblast growth factor
  JOURNAL   Biochem J 336 (Pt 1) (Pt 1), 213-222 (1998)
   PUBMED   9806903
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Mar 8, 2021 this sequence version replaced NM_172334.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ228181.1, FQ234564.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               JAXUCZ010000001.1  212197412-212197573
            163-361             JAXUCZ010000001.1  212197746-212197944
            362-488             JAXUCZ010000001.1  212198147-212198273
            489-589             JAXUCZ010000001.1  212199169-212199269
            590-723             JAXUCZ010000001.1  212199919-212200052
            724-832             JAXUCZ010000001.1  212200367-212200475
            833-896             JAXUCZ010000001.1  212200551-212200614
            897-983             JAXUCZ010000001.1  212200897-212200983
            984-1081            JAXUCZ010000001.1  212201074-212201171
            1082-1209           JAXUCZ010000001.1  212201605-212201732
FEATURES             Location/Qualifiers
     source          1..1209
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1209
                     /gene="Fibp"
                     /note="FGF1 intracellular binding protein"
                     /db_xref="GeneID:282837"
                     /db_xref="RGD:628715"
     exon            1..162
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1151
                     /gene="Fibp"
                     /note="FGF intracellular binding protein; fibroblast
                     growth factor (acidic) intracellular binding protein"
                     /codon_start=1
                     /product="acidic fibroblast growth factor
                     intracellular-binding protein"
                     /protein_id="NP_758837.2"
                     /db_xref="GeneID:282837"
                     /db_xref="RGD:628715"
                     /translation="MTSELDIFVGNTTLIDEDVYRLWLDGYSVNDAVALRVRSGILEQ
                     TGATTGVLQSDTMDHYRTFHMLERLLHAPPKLLHQLIFQIPPSRQALLIERYYTFDEA
                     FVREVLGKKLSKGTKKDLDDISTKTGITLKSCRRQFDNFKRVFKVVEEMRGSLVDNIQ
                     QHFLLSDRLARDYAAIVFFANNRFETGKKKLQYLSFGDFAFCAELMIQNWTLGAVDSQ
                     MDDMDVDLDKEFLQDLKELKVLVADKDLLDLHKSLVCTALRGKLGVFSEMETNFKNLS
                     RGLVNVAAKLTHNKDVRDLFVDLVEKFVEPCRSDHWPLSDVRLFLNQYSASVHSLDGF
                     RHQALWDRYMGTLRGCLLRLYHD"
     exon            163..361
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            362..488
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            489..589
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            590..723
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            724..832
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            833..896
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            897..983
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1081
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1209
                     /gene="Fibp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagtggctct gcggctacta gcccggcccc cggccgtgca agctccagct tcgggcgaac
       61 ccggcccggg catcgtcatg actagcgaac tagacatttt cgtgggcaac acgaccctta
      121 tagatgaaga cgtgtatcgc ctctggctgg atggttactc agtgaacgat gcagtggctc
      181 tgcgagtacg ctccggaatc ctggagcaga cgggagccac cacaggagta ctgcagagcg
      241 acaccatgga ccactaccgc acctttcaca tgcttgagcg tctgcttcac gcgccgccga
      301 agctgctgca ccagctcatc ttccagattc ctccctcccg acaggcactc ctcatcgaga
      361 ggtactacac ctttgacgag gcctttgttc gggaggtctt gggcaagaag ctgtccaagg
      421 gtaccaagaa agaccttgat gacatcagca ccaaaaccgg aattactctc aagagctgcc
      481 ggaggcagtt tgacaacttc aagcgagtct tcaaggtggt ggaagaaatg cggggctccc
      541 tggtggataa catccagcaa cactttctcc tctctgaccg attagccaga gactatgcag
      601 ccatcgtctt ctttgccaac aaccggtttg aaacaggcaa gaaaaagctg cagtatctga
      661 gctttggcga ctttgccttc tgtgctgagc ttatgatcca gaactggacc cttggagccg
      721 tcgactctca gatggatgac atggatgtgg acttagataa ggagtttctc caagacttga
      781 aggagctcaa ggttctagta gctgacaagg accttctaga cttgcacaag agcctggtgt
      841 gtactgccct ccgggggaag ctgggtgtct tctctgagat ggaaaccaac ttcaagaatc
      901 tgtcccgggg gctggtgaac gtggctgcca agctgaccca caataaggat gtcagagacc
      961 tgtttgtgga ccttgtggag aagtttgtgg aaccctgccg ctctgaccac tggccactga
     1021 gtgacgtgag gctcttcctc aaccagtatt cagcgtctgt ccactccttg gatggcttcc
     1081 ggcaccaggc cctctgggac cgctacatgg gcaccctccg tggctgcctt ctgcgccttt
     1141 atcatgatta aagccccttt ccttcctccc tccgacatac cccgagaata aagttgccat
     1201 aagtttgca
//
