LOCUS       NM_001107979            1067 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus four and a half LIM domains 3 (Fhl3), mRNA.
ACCESSION   NM_001107979 XM_001056311 XM_233499
VERSION     NM_001107979.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1067)
  AUTHORS   Kuo JC, Han X, Hsiao CT, Yates JR 3rd and Waterman CM.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   2  (bases 1 to 1067)
  AUTHORS   Coghill ID, Brown S, Cottle DL, McGrath MJ, Robinson PA, Nandurkar
            HH, Dyson JM and Mitchell CA.
  TITLE     FHL3 is an actin-binding protein that regulates
            alpha-actinin-mediated actin bundling: FHL3 localizes to actin
            stress fibers and enhances cell spreading and stress fiber
            disassembly
  JOURNAL   J Biol Chem 278 (26), 24139-24152 (2003)
   PUBMED   12704194
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_233499.4, XM_001056311.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132281,
                              SAMD00132291 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1067
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1067
                     /gene="Fhl3"
                     /note="four and a half LIM domains 3"
                     /db_xref="GeneID:313582"
                     /db_xref="RGD:1307180"
     exon            1..48
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
     exon            49..225
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..936
                     /gene="Fhl3"
                     /codon_start=1
                     /product="four and a half LIM domains protein 3"
                     /protein_id="NP_001101449.1"
                     /db_xref="GeneID:313582"
                     /db_xref="RGD:1307180"
                     /translation="MSEAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQ
                     QLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCS
                     ACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP
                     RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDDDPYCVACFGELFA
                     PKCSSCKRPITGGSGSEGAGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGD
                     QVLCQGCSQAGP"
     exon            226..400
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
     exon            401..570
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
     exon            571..781
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
     exon            782..1067
                     /gene="Fhl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgccccacc cacgccgctc gcgcccaagc tcccgcgccc gcttcgaggg ctcactgggc
       61 accgccacca tgagtgaagc atttgactgt gcaaaatgca atgagtcctt gtacggccgc
      121 aaatacatcc agacagacag cggcccctac tgtgttccct gctacgacaa caccttcgcc
      181 aacacctgtg ccgagtgcca gcagctcatc ggccacgatt caagggaact gttttatgag
      241 gatcgccact tccacgaggg ctgcttccgc tgctgccgct gccagcgctc cctcgccgat
      301 gagcccttca cctgtcagga cagtgagctt ctctgtaatg agtgctactg tacagccttc
      361 tcttcccagt gctctgcctg tggggagacc gtcatgcccg ggtcccggaa gctggagtat
      421 ggaggccaga cgtggcatga acactgcttt ctgtgcagtg gctgtgagca gccactaggc
      481 tcccgctcct tcgtgcctga caagggtgct cactactgcg tgccttgcta tgagaacaaa
      541 tttgctcctc ggtgtgcccg ctgcagcaag acgctgaccc agggcggagt gacatatcgc
      601 gatcagccct ggcatcgaga gtgcctggtc tgcactgggt gccagacgcc cctcgcaggg
      661 cagcagttca catcccggga tgatgatccc tactgtgtgg cctgctttgg agaactcttt
      721 gcacccaagt gcagcagctg caagcgtccc atcacaggtg ggagcggcag cgagggcgca
      781 ggactcggtg gaggcaagta cgtgtccttc gaagaccgac attggcacca cagctgcttt
      841 tcctgtgccc gctgctccac ctccctggtg ggccaaggct ttgtaccaga tggagaccaa
      901 gttctgtgcc agggctgcag ccaagcaggc ccctgagccc aggctcctga ctctcctctt
      961 tcccaaacca agggttcaag actatggctc cttttctgaa ccacttctgg ggcccagccc
     1021 ctccctagaa tgggcctccc cagttcccca ctcatggaga cttcaag
//
