LOCUS       NM_001005538            3470 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus FHF complex subunit HOOK interacting protein 1B
            (Fhip1b), mRNA.
ACCESSION   NM_001005538 XM_215030
VERSION     NM_001005538.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3470)
  AUTHORS   Xu,L., Sowa,M.E., Chen,J., Li,X., Gygi,S.P. and Harper,J.W.
  TITLE     An FTS/Hook/p107(FHIP) complex interacts with and promotes
            endosomal clustering by the homotypic vacuolar protein sorting
            complex
  JOURNAL   Mol Biol Cell 19 (12), 5059-5071 (2008)
   PUBMED   18799622
REFERENCE   2  (bases 1 to 3470)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CV112456.1, BC082011.1, CA339001.1 and BP493980.1.
            
            On Jun 22, 2007 this sequence version replaced NM_001005538.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-246               CV112456.1         1-246
            247-1988            BC082011.1         233-1974
            1989-2379           CA339001.1         265-655
            2380-2491           BP493980.1         122-233             c
            2492-2611           BP493980.1         1-120               c
            2612-3470           BC082011.1         2004-2862
FEATURES             Location/Qualifiers
     source          1..3470
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..3470
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /note="FHF complex subunit HOOK interacting protein 1B"
                     /db_xref="GeneID:293343"
                     /db_xref="RGD:1359585"
     exon            1..119
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            120..451
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     CDS             314..3283
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /note="FTS and Hook-interacting protein; family with
                     sequence similarity 160, member A2"
                     /codon_start=1
                     /product="FHF complex subunit HOOK-interacting protein 1B"
                     /protein_id="NP_001005538.2"
                     /db_xref="GeneID:293343"
                     /db_xref="RGD:1359585"
                     /translation="MEKMNWLSRLASRVPGHRVPQGASLQTPVMADPETCLMVFKNHW
                     SQVVRILERQGSRAAAGGADDLSAVRNHTYQMLTLLAEDRAVPSAPSGPGPLLEFALR
                     EDLLSRVLTWQLQWDEFGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLALLD
                     ACGRPVPSSPALDEGLVLLLSQLCVCVAREPSLLEFFLQPPPEPGAAPRLLLFSRLVP
                     FVHREGTLGQQARDALLLLMALSDGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKI
                     EVPGDDWHCLRREDWIGVPALALFMSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPV
                     MGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARI
                     GSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAA
                     DKFLSLIPRCCRHHAPSPPRPEHASWARGGPSREPGRREDITGPGSPSVDSSSVVTVP
                     RPSTPSRLALFLRQQSLGGSESPGPAPRSPGLTASPTSSPGRRPSPAEEPGELEDNYL
                     EYLREARRGVDRCVRACRTWSAPYDGERPPPEPNPLGSRTKKRSLLPEEDRDNVREGE
                     EENLGSRGLAVGVGDTPGYLPPPQLNGVPGPWPEGAKKVRLVPRLVSQEGVRELLEGT
                     SEGMAGLESFGQELQELEVALSNGGAGSEPPLEPPLPPEEEEAYESFTCPPEPPGPFL
                     SSPLRTLHQLPSQPFTGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRS
                     FLLNTNMVFQPSVKSLLQVLGSVKNKIESFAASQEDFPALLSKAKKYLIARGKLDWAE
                     GPTAGPTPRRSDSLVRSRRPSLGELLLRHAHSPTRARQAVQVLQPGRDGTGLGLGGGS
                     PGASTPVLLPRGGASERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLDT
                     SEEVSVPPISGFGPLNP"
     exon            452..1090
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1249
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1336
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1504
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1584
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1790
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..2582
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            2583..2761
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..2924
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     exon            2925..3444
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3444
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
ORIGIN      
        1 gcctgaggag cgatggcggc ggcctgaact cacctagccc ggccgccgac aggcccgggc
       61 agggcggcgc ggtgcaagcg aaagagacgc gtgggccgca gcgcgcgcag acgcgcaaga
      121 tttgcaacac tggactggac agtgaactct ggccttgcta ctactctagt ttggtgtaat
      181 ctgtggctct gtggccagct actggctcct acagaccgga tgaagcagat tggagacaga
      241 agtggagaaa acctccagct ggtacattct cagagtgtag tcctctggct gctggccctg
      301 tccagcctgc ctcatggaga agatgaactg gctgagcagg ctggcctccc gggttcctgg
      361 tcaccgtgta cctcaagggg ccagtctaca gacccctgtc atggctgacc ctgagacatg
      421 cctcatggtc ttcaagaatc actggtccca ggtggtgcga atcctggagc ggcaaggctc
      481 tcgggcagct gctggaggtg cagatgatct cagtgctgtg agaaaccaca cgtaccaaat
      541 gctaacattg ctggcagagg atcgagcagt tccttcagcc ccctcaggcc ctgggcccct
      601 gctagagttt gctctgcgtg aggatctgct gagccgagta ttgacatggc agctgcaatg
      661 ggatgagttt ggggatgggg tcgaagaacg gcgggctgaa cagctgaaac tatttgagat
      721 gctagtgagc gaagctcggc agcctctgtt gcggcacggg ccagttcgtg aggctctgct
      781 tgccctgctt gatgcctgtg gccgccctgt gcccagtagc ccagcactgg atgaaggcct
      841 ggtgctactt ctcagccagt tgtgtgtgtg tgttgctcgg gagccttcat tgctcgagtt
      901 cttcttgcag ccacccccag agcctggagc tgctccacgt cttctcctct tttctcgcct
      961 tgtccccttt gtccatcgag aaggcaccct gggtcagcag gcccgtgatg ctctacttct
     1021 gctcatggct ctgtcagatg ggagccccac tgtgggccgc tacatcgcag atcactctta
     1081 cttctgcccg gtgctggcca cagggctgag tgccctgtac tcctcactgc ctcgaaagat
     1141 tgaggttcca ggggatgatt ggcactgctt gcgccgggaa gactggatag gagtgcctgc
     1201 cctcgcactc ttcatgagtt ccctagagtt ctgcaatgca gtcattcagg tagctcaccc
     1261 cctggtgcag aagcagctgg ttgactatat ccataatggt ttcctggtgc ctgtcatggg
     1321 ccctgccctg cacaagacct ctgtggagga gatgatcgcg agtaccgcct atctggaact
     1381 tttcctgcgg agcatctcag agcctgcctt gctccgtacc ttcctgcgat tcctgttgtt
     1441 acatcggcat gatacccaca ccatccttga caccctcgtt gcccgtattg gcagcaactc
     1501 ccggctctgc atggtctctc tgagtctctt caggaccctt ctgaacctca gctgtgagga
     1561 tgttctgctg cagctggttc tcaggtatct tgtcccatgt aaccatgtga tgctgagcca
     1621 gaagccagct gtgcgtgatg tggatcttta tggacgggca gccgacaagt ttctctccct
     1681 aatcccacgc tgctgtcgac accatgcccc tagcccacct cgtcctgagc atgcctcgtg
     1741 ggcacgaggt gggcctagca gagagccagg gagaagggag gacatcacgg gccctggaag
     1801 ccccagtgtt gattcttcat ccgtggtaac agtgccccgg ccctccacac catctcgtct
     1861 ggctttgttt ctccgtcagc agagcctagg tggctctgag tccccaggtc cagctcctcg
     1921 atccccaggg cttactgcat caccaacctc cagccctggt cgaagaccca gtcctgcaga
     1981 ggagcctggt gagctagaag acaattacct ggagtatctg cgtgaggcac gccgtggtgt
     2041 agaccgctgt gtccgagcct gccgaacctg gtctgcccct tatgatggcg agcgtccccc
     2101 acctgagcct aaccctcttg gctcccggac taagaaacgc agcctactgc cagaggaaga
     2161 cagggacaat gtgagggaag gagaggagga aaacctaggg agtcgggggc tagctgtggg
     2221 tgtaggggat actcctggct acctaccccc accccagctc aatggggtac cagggccatg
     2281 gccagaagga gccaagaagg ttcgtctggt gccacgattg gtgtcacagg aaggagttag
     2341 ggaattgtta gagggtacct ctgagggcat ggcaggacta gagagctttg ggcaagagct
     2401 ccaggagctg gaggtggcat tgagcaatgg tggagctggc tcagagcctc ccttagagcc
     2461 tccactacct cctgaggagg aggaggccta cgagagcttc acctgccctc ctgagccccc
     2521 tggccccttc ctcagcagcc ctttgcggac tctccaccag ctgcccagcc agcccttcac
     2581 cggccccttc atggctgtgc tctttgccaa actcgagaac atgctgcaga actccgtcta
     2641 tgtcaacttc ctgctgacgg ggctggtggc ccagctggcc tgtcaccccc agcccctgct
     2701 ccgctctttc ctgctcaaca ccaacatggt cttccagccc agtgtcaagt ccctgctgca
     2761 ggtgctgggc tctgtgaaga ataagattga gagctttgcg gcctcccagg aggacttccc
     2821 tgccctgcta tccaaagcca agaagtacct cattgcccgt gggaagctgg actgggctga
     2881 aggtcctaca gcaggaccta ccccccgccg ctctgattcc ctagtgagga gccggaggcc
     2941 atccttgggg gaattactcc tgcggcatgc acacagccca accagggccc gacaggcggt
     3001 acaggttctt caacctgggc gagatggaac aggacttgga ctaggtgggg gctctccagg
     3061 ggcttcaact ccagttctgc tcccccgggg tggggcttct gagcgccaag gtgaggctct
     3121 tcgagtcaag aatgctgtct actgtgcagt cattttccct gagtttctca aggagttggc
     3181 tgccatctcc caggcccatg ctgtcacctc gcctttcttg ttggatactt cagaggaggt
     3241 atctgttcct cccatctcag gctttgggcc cctcaatcct taattttctt ccatggacaa
     3301 tcagggcctt ctgtgttctg ggctgaaatc caggacacgg gctccttttt atgtttggag
     3361 gcagtggcaa atggactttt taatttattt cagatgaatg ttttatgaga acttgttgca
     3421 atatgtataa aagggaaatc tctaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
