LOCUS       NP_001005538             989 aa            linear   ROD 02-JUN-2024
DEFINITION  FHF complex subunit HOOK-interacting protein 1B [Rattus
            norvegicus].
ACCESSION   NP_001005538 XP_215030
VERSION     NP_001005538.2
DBSOURCE    REFSEQ: accession NM_001005538.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 989)
  AUTHORS   Xu,L., Sowa,M.E., Chen,J., Li,X., Gygi,S.P. and Harper,J.W.
  TITLE     An FTS/Hook/p107(FHIP) complex interacts with and promotes
            endosomal clustering by the homotypic vacuolar protein sorting
            complex
  JOURNAL   Mol Biol Cell 19 (12), 5059-5071 (2008)
   PUBMED   18799622
REFERENCE   2  (residues 1 to 989)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CV112456.1, BC082011.1, CA339001.1 and BP493980.1.
            
            On Jun 22, 2007 this sequence version replaced NP_001005538.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..989
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     Protein         1..989
                     /product="FHF complex subunit HOOK-interacting protein 1B"
                     /note="FTS and Hook-interacting protein; family with
                     sequence similarity 160, member A2"
                     /calculated_mol_wt=107753
     Region          97..426
                     /region_name="RAI16-like"
                     /note="Retinoic acid induced 16-like protein; pfam10257"
                     /db_xref="CDD:370927"
     Region          465..510
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q66H54.1)"
     Site            467
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8N612; propagated from
                     UniProtKB/Swiss-Prot (Q66H54.1)"
     Region          524..556
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q66H54.1)"
     Site            524
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3U2I3; propagated from
                     UniProtKB/Swiss-Prot (Q66H54.1)"
     Site            537
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q3U2I3; propagated from
                     UniProtKB/Swiss-Prot (Q66H54.1)"
     Site            543
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q66H54.1)"
     Site            547
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q66H54.1)"
     Region          756..849
                     /region_name="DUF5917"
                     /note="Family of unknown function (DUF5917); pfam19314"
                     /db_xref="CDD:466037"
     Region          936..967
                     /region_name="KELAA"
                     /note="KELAA motif; pfam19311"
                     /db_xref="CDD:466035"
     CDS             1..989
                     /gene="Fhip1b"
                     /gene_synonym="Fam160a2; FHIP"
                     /coded_by="NM_001005538.2:314..3283"
                     /db_xref="GeneID:293343"
                     /db_xref="RGD:1359585"
ORIGIN      
        1 mekmnwlsrl asrvpghrvp qgaslqtpvm adpetclmvf knhwsqvvri lerqgsraaa
       61 ggaddlsavr nhtyqmltll aedravpsap sgpgpllefa lredllsrvl twqlqwdefg
      121 dgveerraeq lklfemlvse arqpllrhgp vreallalld acgrpvpssp aldeglvlll
      181 sqlcvcvare psllefflqp ppepgaaprl llfsrlvpfv hregtlgqqa rdallllmal
      241 sdgsptvgry iadhsyfcpv latglsalys slprkievpg ddwhclrred wigvpalalf
      301 msslefcnav iqvahplvqk qlvdyihngf lvpvmgpalh ktsveemias taylelflrs
      361 isepallrtf lrflllhrhd thtildtlva rigsnsrlcm vslslfrtll nlscedvllq
      421 lvlrylvpcn hvmlsqkpav rdvdlygraa dkflsliprc crhhapsppr pehaswargg
      481 psrepgrred itgpgspsvd sssvvtvprp stpsrlalfl rqqslggses pgpaprspgl
      541 tasptsspgr rpspaeepge lednyleylr earrgvdrcv racrtwsapy dgerpppepn
      601 plgsrtkkrs llpeedrdnv regeeenlgs rglavgvgdt pgylpppqln gvpgpwpega
      661 kkvrlvprlv sqegvrelle gtsegmagle sfgqelqele valsnggags epplepplpp
      721 eeeeayesft cppeppgpfl ssplrtlhql psqpftgpfm avlfaklenm lqnsvyvnfl
      781 ltglvaqlac hpqpllrsfl lntnmvfqps vksllqvlgs vknkiesfaa sqedfpalls
      841 kakkyliarg kldwaegpta gptprrsdsl vrsrrpslge lllrhahspt rarqavqvlq
      901 pgrdgtglgl gggspgastp vllprggase rqgealrvkn avycavifpe flkelaaisq
      961 ahavtspfll dtseevsvpp isgfgplnp
//
