LOCUS       XM_039110824            4623 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus FGR proto-oncogene, Src family
            tyrosine kinase (Fgr), transcript variant X1, mRNA.
ACCESSION   XM_039110824
VERSION     XM_039110824.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039110824.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4623
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4623
                     /gene="Fgr"
                     /gene_synonym="p55-Fgr"
                     /note="FGR proto-oncogene, Src family tyrosine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 9 ESTs, 50 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 77 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:79113"
                     /db_xref="RGD:621319"
     CDS             154..1707
                     /gene="Fgr"
                     /gene_synonym="p55-Fgr"
                     /codon_start=1
                     /product="tyrosine-protein kinase Fgr isoform X1"
                     /protein_id="XP_038966752.1"
                     /db_xref="GeneID:79113"
                     /db_xref="RGD:621319"
                     /translation="MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSI
                     SPQPISPAFLNVGNIRSVSGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDW
                     WEARSLSSGRTGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSDGNPQGAFLIRE
                     SETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVN
                     DGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTKV
                     AVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFL
                     KDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLA
                     RLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGM
                     NNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTE
                     PQYQPGDQT"
ORIGIN      
        1 ttcttgtgga gttgctcaca gaacagagct gctggggaaa gtttggctac ttcccagatc
       61 tcttcaagag actatagtgg ccccagcttc tccctaaccc tggtctgtag gagactgtca
      121 ctttcatcct ggcacaagag caggacacct ggaatgggct gtgtgttctg caagaagtta
      181 gagcctgcac ccaaggagga tgttggcctg gaaggggact tccggagcca aggcgctgaa
      241 gaacgctatt accctgaccc tactcaaggc cggtcttcgt ccatctcgcc tcagcccatc
      301 agccctgctt tccttaatgt tggcaacata agaagcgtct ctgggacggg agtgaccata
      361 ttcgtcgccc tgtatgacta tgaggccagg acaggggatg acctcacctt caccaaaggc
      421 gagaagttcc acatcctgaa caatacggag tatgactggt gggaggctag gtccctgagc
      481 tccggacgca cgggctatgt tcccagcaac tatgtggctc ccgtggattc catccaggct
      541 gaagagtggt acttcggaaa gatcagcaga aaggatgcag agaggcagct tctctccgat
      601 ggcaaccctc aaggggcctt tctcattcgg gaaagcgaga ccaccaaagg tgcctactcc
      661 ctgtccatcc gtgactggga ccagaacaga ggcgaccaca taaagcatta caagatccga
      721 aagctggaca tgggtggcta ctacatcacc acgcgggccc agttcgaatc cgtgcaggac
      781 ctggtgcggc actacatgga agtgaatgac ggtctatgct acttgctcac ggcaccctgt
      841 atggtcatga agccccagac tctaggcctg gctaaggatg cctgggagat cgaccgtaac
      901 tccatagcac ttgaccgcag gctgggcacc ggctgctttg gagacgtgtg gctgggcacg
      961 tggaactgta gcacaaaggt ggcagtgaaa acgctgaagc caggcaccat gtcgccgaag
     1021 gccttcctgg aggaggcaca gatcatgaaa ctgctgaggc acgacaagct ggtgcagctg
     1081 tacgcggtgg tgtcagagga acccatttat attgtgacag agttcatgtg ctatggtagc
     1141 ttgctggatt tcctaaagga tcgaaagggt cacaacttga tgctgcccaa tctagtggac
     1201 atggctgccc aggtagcaga gggcatggcc tacatggagc gcatgaacta tatccaccga
     1261 gacctgagag cagccaacat cctggtgggg gaacatctaa tatgcaagat cgctgacttt
     1321 gggttggcac gcctcatagt ggatgatgag tacaaccccc aacaaggaac caagtttccc
     1381 atcaagtgga cagccccaga ggctgctctc tttggcagat tcactgtcaa atcagacgtg
     1441 tggtcctttg ggattctgct cactgaactg atcaccaagg gcagagttcc atacccaggt
     1501 atgaacaacc gggaagtgtt ggaacaggta gagcacggct accacatgcc atgccctccg
     1561 ggatgcccag tatccctgta tgaggtcatg gagcagacct ggcgtctgga tccagaggag
     1621 aggcccacct ttgagtacct gcagtctttc ctggaagact atttcacctc cacagaacca
     1681 cagtatcagc ccggagacca gacatagcct gactgggtat cagtgaccct ctgagactat
     1741 gtactaaccc ttgccaatcc ccagggcact ctggtcccag tgccccgaga cttggaaccc
     1801 tgtggaatcc tagcacgtcg gaaaaagtcc gaagctctga agccatttta tagagggtgc
     1861 aaatggagac tagaaattca tctcttacct tcgctggccc caagcactct ttcttccctt
     1921 cccacccatg ccccatgcaa aaatctaggg cacccagtca tttcacagac ggagtaaatg
     1981 gatgctcaga gttcatctct cgtacactct gaccccagta ccatttttcc tgtcccatta
     2041 ggctcctacg taccgttagt ccccccccca tctcctaaaa atactcatac attgtgtagt
     2101 tatttataaa attgtatttc tcttcttcca cttacctctt atccctgctt tctaacctcc
     2161 tgtcagcccg ctccagccca gaccttaaga gtttaattct gaggttctct tgggtttctc
     2221 tacgttacaa aggcagggga cgtctctgct tgattccccg tcttcagact ggatgctgtg
     2281 gtccaggccc aggtctgaag gagagagcca ttgaaggctc accatctctc tgagtggtct
     2341 gaatgtgttt attcgttata aacgaacagt gatgatcgag ctgtgacaac tgccggagcc
     2401 atctttgggg cggagtggtg gtccgcagga ggcgaacagg atagctttgg ctatttgtgg
     2461 ggcggggggg ggcagtgtgg gggtgtcgag cagttccctc ttacctacta agtacaaggt
     2521 acccagtgta tggagtttca ggataccccc gtgtcccaca cgtcagtttg ccatgagtcg
     2581 agaggcgcgc aaagcaggtg actggaaata gacacatgtg gttttgaatc tggatacagc
     2641 taattcctca cctgcttaga gctgacttcc cagccgtcac aggaacactc gcacagttag
     2701 gcctctacag ctgtcaggct ccccagaaca gagcaagagg agggtgaagg ggaaaggcct
     2761 agctcatagg acctcactgg ggagtggggt gggttcttcc ccaccccagg gagctttcgg
     2821 agaccttagg aagtattttt ttttcttttt ttttggagct ggggaccgaa cccagggcct
     2881 tgcgcttgct aggcaagcgc tctaccgctg agctaaatcc ccaaccccag gaagtatttt
     2941 tattatagtg actgggagca cttactagct gggaccaggg atgatagatg atctttgatg
     3001 tacttcttgg gtcctccgtg gagaaactga ccgctggcag gcctctgttt ggaaaccagg
     3061 gaagtaggaa atgtggatct ccacctctcc tgtcaggaag tctttattgg cttatgatgg
     3121 gaaagacgag aggagtctgg gagctgggag tcgctgaagc actaggcaat tactaagaat
     3181 tgactctgat gcactcttca ctgtgcagga ccctgggcat aaaaaaatga gggagaaggg
     3241 gctggggatt tagctcagtg gtagagcgct tgcctagcaa gagcaaggcc ctgggttcgg
     3301 ttcccagctc cggaaagaaa aaaaaggaaa aaaaaatgag ggagagctgc tcttgctctg
     3361 gaggcttgcc cttgggtgaa gaaataatga atgaatgaat gaatgaatga atgaatgaac
     3421 aaatacttac cttttaagaa aaaaaatgag gtatggactc atagaaccca ggatgacctc
     3481 gaactcccaa tcctcctgcc tccagcttcc aaatgctggg attacagttg tgtcccacca
     3541 tgcccagttt aatctattaa gctgactgga acatggcggc acacaccttt agtcccagca
     3601 ctggggaggc ggaagcaagc agatgggcag tgtttgaagc cagcatagtc tatgcagtga
     3661 gttccaggac agctagggat aaaggtgaga ccctgtctca aacaaaagca aacaagcatt
     3721 cccgctgact gtcagatatt tttgcggcct ttctgcccca tgtaatcaaa tgccgagact
     3781 gtttcctatg attagttcct ctgaataaga aaaccaaggg tcaggggtta cctgatatgc
     3841 ctggattact cagatgcaca tagtagagct gatctacaca gagcccatgg tctcttcact
     3901 agacttcatt atctctgggt tttggaaaag ggtggggtgt gtgtgtgtgt gtgtgtgtgt
     3961 gtgtgtgtgt gtgtgtgtgt gtgctctcta cttaacagca aaaagatgcc ctagaaccct
     4021 ccgccaaact gaggaatcta aaggaaaggg gcagggtgac atctactgag agttccctct
     4081 gaccaggttt gtgttgaatg gaaacaaaat atggagtgaa ggtgatggag agatggctca
     4141 gtggttaggg gccctgactg ctctcttcca gaggacttgg gttcaattcc cagcaaccac
     4201 atggccgctc acaactgtct gtactccaag atctgacact ctcgcacagg cagaacacca
     4261 atgcacgcaa aataaaaata aacaaattaa agattaaaat aaaatttaga tggagagaat
     4321 ccaggcaaac actcaggtac caaagcatct tcaggccata ggggtcctag ccagccaaat
     4381 tcactagaac ctgatatgca agccagaagg tagtgttgtt tctctcttcc tgccctgggg
     4441 ttaaatagta agagcacagc tctgtagccg tttcccactg tgaaccctgc cactgtgaac
     4501 cctgccactg tgaatcctgc ttctaccact tgctggctct gtggttctat gcgagtgttt
     4561 aatttcgcca agctccagtt ttgctcaact gtgaagtagc attaaatgtt ttaatacacg
     4621 tca
//
