LOCUS       XM_006239082            1777 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus FGR proto-oncogene, Src family
            tyrosine kinase (Fgr), transcript variant X6, mRNA.
ACCESSION   XM_006239082
VERSION     XM_006239082.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006239082.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006239082.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1777
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1777
                     /gene="Fgr"
                     /gene_synonym="p55-Fgr"
                     /note="FGR proto-oncogene, Src family tyrosine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 ESTs, 50 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 106 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:79113"
                     /db_xref="RGD:621319"
     CDS             224..1777
                     /gene="Fgr"
                     /gene_synonym="p55-Fgr"
                     /codon_start=1
                     /product="tyrosine-protein kinase Fgr isoform X1"
                     /protein_id="XP_006239144.1"
                     /db_xref="GeneID:79113"
                     /db_xref="RGD:621319"
                     /translation="MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSI
                     SPQPISPAFLNVGNIRSVSGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDW
                     WEARSLSSGRTGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSDGNPQGAFLIRE
                     SETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVN
                     DGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTKV
                     AVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFL
                     KDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLA
                     RLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGM
                     NNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTE
                     PQYQPGDQT"
ORIGIN      
        1 ccctgcccag agtaggtagt agggacaggg gcgggtagca cttcactttc ccctcacatc
       61 gttcctgaaa attagggttg gctcgcccca gatcgggtca ccagcagctg gctcccttga
      121 gaccaggtag gcggccaaac caggaggagg ctgacccggc aggtgtcgcc ccgcccctgt
      181 ccgtcctcgc cctggaagga agatttagag caggacacct ggaatgggct gtgtgttctg
      241 caagaagtta gagcctgcac ccaaggagga tgttggcctg gaaggggact tccggagcca
      301 aggcgctgaa gaacgctatt accctgaccc tactcaaggc cggtcttcgt ccatctcgcc
      361 tcagcccatc agccctgctt tccttaatgt tggcaacata agaagcgtct ctgggacggg
      421 agtgaccata ttcgtcgccc tgtatgacta tgaggccagg acaggggatg acctcacctt
      481 caccaaaggc gagaagttcc acatcctgaa caatacggag tatgactggt gggaggctag
      541 gtccctgagc tccggacgca cgggctatgt tcccagcaac tatgtggctc ccgtggattc
      601 catccaggct gaagagtggt acttcggaaa gatcagcaga aaggatgcag agaggcagct
      661 tctctccgat ggcaaccctc aaggggcctt tctcattcgg gaaagcgaga ccaccaaagg
      721 tgcctactcc ctgtccatcc gtgactggga ccagaacaga ggcgaccaca taaagcatta
      781 caagatccga aagctggaca tgggtggcta ctacatcacc acgcgggccc agttcgaatc
      841 cgtgcaggac ctggtgcggc actacatgga agtgaatgac ggtctatgct acttgctcac
      901 ggcaccctgt atggtcatga agccccagac tctaggcctg gctaaggatg cctgggagat
      961 cgaccgtaac tccatagcac ttgaccgcag gctgggcacc ggctgctttg gagacgtgtg
     1021 gctgggcacg tggaactgta gcacaaaggt ggcagtgaaa acgctgaagc caggcaccat
     1081 gtcgccgaag gccttcctgg aggaggcaca gatcatgaaa ctgctgaggc acgacaagct
     1141 ggtgcagctg tacgcggtgg tgtcagagga acccatttat attgtgacag agttcatgtg
     1201 ctatggtagc ttgctggatt tcctaaagga tcgaaagggt cacaacttga tgctgcccaa
     1261 tctagtggac atggctgccc aggtagcaga gggcatggcc tacatggagc gcatgaacta
     1321 tatccaccga gacctgagag cagccaacat cctggtgggg gaacatctaa tatgcaagat
     1381 cgctgacttt gggttggcac gcctcatagt ggatgatgag tacaaccccc aacaaggaac
     1441 caagtttccc atcaagtgga cagccccaga ggctgctctc tttggcagat tcactgtcaa
     1501 atcagacgtg tggtcctttg ggattctgct cactgaactg atcaccaagg gcagagttcc
     1561 atacccaggt atgaacaacc gggaagtgtt ggaacaggta gagcacggct accacatgcc
     1621 atgccctccg ggatgcccag tatccctgta tgaggtcatg gagcagacct ggcgtctgga
     1681 tccagaggag aggcccacct ttgagtacct gcagtctttc ctggaagact atttcacctc
     1741 cacagaacca cagtatcagc ccggagacca gacatag
//
