LOCUS       NM_201421               2844 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus FGFR1 oncogene partner 2 (Fgfr1op2), mRNA.
ACCESSION   NM_201421 XM_342786
VERSION     NM_201421.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2844)
  AUTHORS   Lin,A., Hokugo,A., Choi,J. and Nishimura,I.
  TITLE     Small cytoskeleton-associated molecule, fibroblast growth factor
            receptor 1 oncogene partner 2/wound inducible transcript-3.0
            (FGFR1OP2/wit3.0), facilitates fibroblast-driven wound closure
  JOURNAL   Am J Pathol 176 (1), 108-121 (2010)
   PUBMED   19959814
  REMARK    GeneRIF: FGFR1OP2/wit3.0 may regulate cell motility and stimulate
            wound closure.
REFERENCE   2  (bases 1 to 2844)
  AUTHORS   Sukotjo,C., Lin,A., Song,K., Ogawa,T., Wu,B. and Nishimura,I.
  TITLE     Oral fibroblast expression of wound-inducible transcript 3.0
            (wit3.0) accelerates the collagen gel contraction in vitro
  JOURNAL   J Biol Chem 278 (51), 51527-51534 (2003)
   PUBMED   14527947
REFERENCE   3  (bases 1 to 2844)
  AUTHORS   Sukotjo,C., Abanmy,A.A., Ogawa,T. and Nishimura,I.
  TITLE     Molecular cloning of wound inducible transcript (wit 3.0)
            differentially expressed in edentulous oral mucosa undergoing tooth
            extraction wound-healing
  JOURNAL   J Dent Res 81 (4), 229-235 (2002)
   PUBMED   12097305
  REMARK    GeneRIF: expressed by the fibroblasts associated with tooth
            extraction wound-healing (wit 3.0)
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_201421.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY426740.1, SRR26643293.26057.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-317               JAXUCZ010000004.1  181222298-181222614
            318-454             JAXUCZ010000004.1  181230064-181230200
            455-572             JAXUCZ010000004.1  181232822-181232939
            573-715             JAXUCZ010000004.1  181234057-181234199
            716-829             JAXUCZ010000004.1  181236744-181236857
            830-943             JAXUCZ010000004.1  181239382-181239495
            944-2844            JAXUCZ010000004.1  181241337-181243237
FEATURES             Location/Qualifiers
     source          1..2844
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..2844
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /note="FGFR1 oncogene partner 2"
                     /db_xref="GeneID:362463"
                     /db_xref="RGD:1303233"
     exon            1..317
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     exon            318..454
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     CDS             320..1081
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /note="wound inducible transcript 3.0 protein;
                     Wit3.0_beta; Wit3.0_alpha"
                     /codon_start=1
                     /product="FGFR1 oncogene partner 2 homolog"
                     /protein_id="NP_958824.2"
                     /db_xref="GeneID:362463"
                     /db_xref="RGD:1303233"
                     /translation="MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALSKRVEAMK
                     QYQEEIQELNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMS
                     KYREQMFRLLMASKKDDPGIIMKLKEQHSKIDMVHRNSCEGFFLDASRHILEAPQHGL
                     ERRHLEANQNELQAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREIL
                     QITRESFLNLRKDDASESTSLSALVTNSDLSLRKS"
     exon            455..572
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     exon            573..715
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     exon            716..829
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     exon            830..943
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
     exon            944..2844
                     /gene="Fgfr1op2"
                     /gene_synonym="Wit3.0"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcggaggga agtctcgcga ggcttgtcgc tgtgtggctg ccagtagcgg aggttctggt
       61 ccgcccggga tggagccgag gcaagcgggc tgccggatcc tccctgccgc tgtgtgagca
      121 gggctgtgtg tccgctcgct gagcaggcgc agcgaggccg cggagagcac tctctgggcg
      181 cctccatctc gcgggtggtg gtcgccgtct ctgacggctg agggggactg aagctgagtg
      241 gaaaaacacg agtgggtgaa cctctgagcc gggctccctg tctccgtgct ctcactgagc
      301 tcctgccggg aacagagaaa tgagctgcac cattgagaag gcacttgctg atgctaaggc
      361 ccttgttgaa cggttgagag accatgatga tgcagcagag tctctcatcg aacagaccac
      421 tgccctcagc aagcgagtgg aagccatgaa acagtatcag gaagaaatcc aagaacttaa
      481 tgaagtagca agacatcggc cacgatccac actagttatg ggaatccagc aagaaaacag
      541 acaaatcaga gaattacaac aagagaacaa agaactgcgc acatccttgg aagagcacca
      601 gtctgccttg gaactgataa tgagcaagta tcgagagcag atgttcagat tgctaatggc
      661 cagcaagaag gacgacccgg gcataataat gaagttaaag gagcagcact caaagattga
      721 catggtacat cgtaacagct gcgaaggatt cttcctggat gcatctcggc acatccttga
      781 agcacctcag cacggactgg agaggaggca cttggaagca aatcagaatg agttgcaagc
      841 acatgttgac cagatcaccg agatggcagc agtaatgaga aaagctattg aaattgacga
      901 acagcagggt tgcaaggaac aggagcgcat atttcaactt gaacaagaaa acaaaggctt
      961 gagagagatc cttcagataa ctcgagaatc ctttttgaac cttcggaagg atgatgcgtc
     1021 agagagtaca tctctgtccg ccttagtgac taacagtgac ctgagtctga ggaagagctg
     1081 agtggttggc tgtggtcact aagacgggcc caggagtgag tggatggatg aacataaacc
     1141 caacttcagt cagcctcttt cctctagtat gtcaggggca ctggcgaaga gacagtagca
     1201 ggatgtatag ccagtggtca taaactagat cccagtcaca gctcgacagg aaaacctggg
     1261 ccacagagtg aacattgagt ctccaaggtg ctgctgagga ctgcaatttg agaagtgctg
     1321 ttggcctctt ggatgagata tggatcaccc tgaatgctcc taataaacgt cggaaagcct
     1381 aaattatcac aactccaaaa gaaggttggt gtggtgttct ggatggaaga ctttgttctg
     1441 agtcctgtcc ttctgttcag tgtcagagtc agcatagctt atgtatgtac cgcttctgtc
     1501 tcggtgctcc catccccctg cccatctgtt catcgccggc agttcacatt tacaggctat
     1561 aggaatatgt cactcgcatc acaaactgaa gaaaggaata tacttgcacc tagttcccat
     1621 aactcttagc tagcagttat tcgtgacttg cttgagtata tgtacctcag gaaggaagga
     1681 aagacaagaa tatactttct aagaaagaca gccatatata gacacattta gtaggttaaa
     1741 ctactttgag agactatgtt tggttctctg ttaacaatga gcctggctct tcctcctctc
     1801 tacatgatgt ttaaggatac aggacagagg ggttggggat ttagctcagt ggtagagcgc
     1861 ttgcctagca accgcaaggc cctgggttcg gtccccagct cctaaaaaaa gggaaaaaaa
     1921 aaaggataca ggatagctca ctagtacaca gagttggcat atttaatgta ataagatagg
     1981 tatggtcatt tccaagtaaa tttggaattc ctttgttatt taagaaatca ctcttcaaac
     2041 atataagtag aagcaggttc caaaatcaaa gttctgggac tgagtctaaa ccctgtttag
     2101 ttcttataac ctgtgagttt tccctacaac ctgtgactca gaaactggca gtgaagtgtg
     2161 ggcccacagg cattgtgctt tgcactttaa aaaaaaaaaa agcttaagac cacaagatag
     2221 agaagtgtgc tttaatacca ttgcaaccta aactcttctg tagtgatcag aataaaagaa
     2281 taaaagattg tgaaatacgg caaaaaatat acaatacttg tatgtgaagt tagcacagat
     2341 aaaaagtaaa tcatttgtaa gtacatatta ctttgcagtg taattttatg tgtaatttca
     2401 tgtattggca aaattcatag gacttttact tgagaacctt tcattctgaa gtttgaggtg
     2461 agtggggtca taggtcaggt aggaaagggc cagtacccca ggtgataaac cgttgtcatg
     2521 cagaggcctt aatattttat attataggtg aatttatttc taagactttt ctattggttc
     2581 ttggagagtg tcccttagtt tagtggtcat tctttcatgt agtttggtcc caggccagaa
     2641 tcttagaaga aaggctacac agttgagatg aggcagaatc aaggagtgag tagttctatt
     2701 gtgaaatgtt atttcagaag taattatttt tataaaaaaa ttatttatcc tttgtcttct
     2761 tggatataag tttaaggttg tgaatattga aagacatttg cattgttctt agcaagtttt
     2821 ccatccctcc tatcaccccc cccc
//
