LOCUS       NM_022603               1083 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus fibroblast growth factor binding protein 1
            (Fgfbp1), mRNA.
ACCESSION   NM_022603
VERSION     NM_022603.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1083)
  AUTHORS   Zhu,H.Y., Bai,W.D., Liu,J.Q., Zheng,Z., Guan,H., Zhou,Q., Su,L.L.,
            Xie,S.T., Wang,Y.C., Li,J., Li,N., Zhang,Y.J., Wang,H.T. and
            Hu,D.H.
  TITLE     Up-regulation of FGFBP1 signaling contributes to miR-146a-induced
            angiogenesis in human umbilical vein endothelial cells
  JOURNAL   Sci Rep 6, 25272 (2016)
   PUBMED   27121396
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1083)
  AUTHORS   Yamanaka,Y., Kitano,A., Takao,K., Prasansuklab,A., Mushiroda,T.,
            Yamazaki,K., Kumada,T., Shibata,M., Takaoka,Y., Awaya,T., Kato,T.,
            Abe,T., Iwata,N., Miyakawa,T., Nakamura,Y., Nakahata,T. and
            Heike,T.
  TITLE     Inactivation of fibroblast growth factor binding protein 3 causes
            anxiety-related behaviors
  JOURNAL   Mol Cell Neurosci 46 (1), 200-212 (2011)
   PUBMED   20851768
REFERENCE   3  (bases 1 to 1083)
  AUTHORS   Tassi,E., Walter,S., Aigner,A., Cabal-Manzano,R.H., Ray,R.,
            Reier,P.J. and Wellstein,A.
  TITLE     Effects on neurite outgrowth and cell survival of a secreted
            fibroblast growth factor binding protein upregulated during spinal
            cord injury
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 293 (2), R775-R783 (2007)
   PUBMED   17553847
  REMARK    GeneRIF: FGF-BP is an early response gene after spinal cord injury
            and that its upregulation in regenerating spinal cord tissue may
            provide a molecular mechanism for enhancing the initial
            FGF2-mediated neurotrophic effects occurring after such tissue
            damage
REFERENCE   4  (bases 1 to 1083)
  AUTHORS   Beer,H.D., Bittner,M., Niklaus,G., Munding,C., Max,N., Goppelt,A.
            and Werner,S.
  TITLE     The fibroblast growth factor binding protein is a novel interaction
            partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity:
            implications for epithelial repair
  JOURNAL   Oncogene 24 (34), 5269-5277 (2005)
   PUBMED   15806171
REFERENCE   5  (bases 1 to 1083)
  AUTHORS   West,D.C., Rees,C.G., Duchesne,L., Patey,S.J., Terry,C.J.,
            Turnbull,J.E., Delehedde,M., Heegaard,C.W., Allain,F.,
            Vanpouille,C., Ron,D. and Fernig,D.G.
  TITLE     Interactions of multiple heparin binding growth factors with
            neuropilin-1 and potentiation of the activity of fibroblast growth
            factor-2
  JOURNAL   J Biol Chem 280 (14), 13457-13464 (2005)
   PUBMED   15695515
REFERENCE   6  (bases 1 to 1083)
  AUTHORS   Aigner,A., Malerczyk,C., Houghtling,R. and Wellstein,A.
  TITLE     Tissue distribution and retinoid-mediated downregulation of an
            FGF-binding protein (FGF-BP) in the rat
  JOURNAL   Growth Factors 18 (1), 51-62 (2000)
   PUBMED   10831072
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Nov 26, 2020 this sequence version replaced NM_022603.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF142758.1, SRR22582416.13165.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1083              JAXUCZ010000014.1  71318883-71319965
FEATURES             Location/Qualifiers
     source          1..1083
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1083
                     /gene="Fgfbp1"
                     /note="fibroblast growth factor binding protein 1"
                     /db_xref="GeneID:64535"
                     /db_xref="RGD:621211"
     exon            1..1083
                     /gene="Fgfbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..726
                     /gene="Fgfbp1"
                     /note="FGF-BP; FGF-BP1; FGFBP-1; FGF-binding protein 1;
                     growth factor-binding protein 1"
                     /codon_start=1
                     /product="fibroblast growth factor-binding protein 1
                     precursor"
                     /protein_id="NP_072125.2"
                     /db_xref="GeneID:64535"
                     /db_xref="RGD:621211"
                     /translation="MRIHSLILLSFLLLAAQVLSEKVRKTAKNVPDSTTEEDMSPSLG
                     KARNKQRSRTSKSMTHGKFVTKDQATCRWAVTEEELGINLKVQCTRADQEFSCVFAGD
                     PTGCLKYDKDQTYWKQVARTLRKQKNICENSKSVLKTRVCRKKFPESNLKVVNPRKEK
                     AEVSPREHNKVQEAVSMEPNKVKVDITTSPAATVAVKDSECLEDPDVLTQRKTALEFC
                     GESWSSFCTFFLNMLQATSC"
ORIGIN      
        1 gctgtcgcca tgagaatcca cagcctcatc ctgctctctt tccttctcct ggctgctcag
       61 gtactctcgg aaaaggtcag aaagacagcc aagaatgtac cagacagcac aacggaggag
      121 gatatgtctc cctctttggg gaaggcacgg aataagcaga ggagcaggac atccaaatct
      181 atgacccatg gcaagtttgt caccaaagac caagccacat gcagatgggc tgtgactgag
      241 gaggagctgg gcatcaacct gaaggtccag tgcacacgag ccgatcagga gttttcttgt
      301 gttttcgctg gtgatccaac cggctgcctt aaatacgaca aagaccagac ctactggaaa
      361 caagtcgccc gcacactgcg caaacagaag aatatctgtg agaactccaa gagtgtcttg
      421 aagaccagag tgtgcagaaa gaaatttcca gagtctaacc tcaaggtggt aaaccccagg
      481 aaggagaaag cagaggtctc cccaagggag cacaacaagg tccaagaagc tgtctccatg
      541 gagccaaaca aggtcaaagt ggacatcacc accagcccag ctgcgaccgt ggctgtcaaa
      601 gattcagagt gtctagagga cccagatgtc ctcacccaga ggaagaccgc cctggagttc
      661 tgtggggaat cttggagctc cttctgcaca ttcttcctca acatgttaca ggccacatca
      721 tgctaacgaa gtcagagaga gagcagccta agacatgtgg tatcagagcc ccactgtttg
      781 ctggaaactc cccgggttcc cactaagaca caaacatttc caatacggga acaaagtgaa
      841 gtatttaaac agattttgta aattttgttt tttgtgtctt agaatttgct ttattttgtt
      901 tttttacatt cttagatgtg cttttcagag actgtttacc tcagcgtaat cttccatgga
      961 ctacaaacct aggttcatat aagcagtgga tatatacatc caagtgataa tgtccatgca
     1021 aggaattgtt ggctgtattt accaagataa taaagttctg ggcattctca gaaatgccac
     1081 caa
//
